The Alpha-Melanocyte Stimulating Hormone Induces Conversion of Effector T Cells into Treg Cells by Andrew W. Taylor, Darren J. Lee

“…Therefore, we further analyzed the α-MSH-induced Treg cells for expression of effector and regulatory T-cell markers. …”
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Cellular Plasticity in Prostate Cancer Bone Metastasis by Dima Y. Jadaan, Mutaz M. Jadaan, John P. McCabe

“…Overall, most stem cell markers analysed, except for CXCR4, were positively expressed in bone metastasis tissues, while the expression of EMT and MET markers was heterogeneous between and within samples. …”
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The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival by Changjun He, Haiquan Qiao, Hongchi Jiang, Xueying Sun

“…B7-H4 is one of the most recently identified members of B7 superfamily of costimulatory molecules serving as an inhibitory modulator of T-cell response. B7-H4 is broadly expressed in human peripheral tissues and inducibly expressed in immune cells. …”
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The liver’s dilemma: sensing real danger in a sea of PAMPs: the (arterial) sinusoidal segment theory by Andrea Henriques-Pons, Natália Vacani-Martins, Carina de Lima Pereira dos Santos, Marcelo Meuser-Batista

“…Most cells express Fas-L, IL-10, TGF-β, low levels of co-stimulatory molecules, lack of or have low levels of MHC-I and/or MHC-II expression. …”
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Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior by M. Leo, M. Schulte, L.-I. Schmitt, M. Schäfers, C. Kleinschnitz, T. Hagenacker

“…Transient receptor potential vanilloid-1 (TRPV1) is a nonselective cation channel, predominantly expressed in sensory neurons. TRPV1 is known to play an important role in the pathogenesis of inflammatory and neuropathic pain states. …”
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Ly6E on tumor cells impairs anti-tumor T-cell responses: a novel mechanism of tumor-induced immune exclusion by Lan Hailin, Chen Yiting, Wu Yue, Li Lijun, Zhang Renlu, Chen Yunhan, Zhu Yanyang, Zhang Qiuyu

“…Methods TCGA database and Kaplan–Meier plotter database were used to evaluate the correlation between Ly6E expression levels and cancer patient survival. After analyzing Ly6E expression levels in human breast cancer tissues and tumor cell lines, we generated Ly6E knockout (KO) and overexpression (OE) mouse cell lines. …”
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Integrated Single-Cell and RNA Sequencing Analysis Identifies Key Immune Cell and Dendritic Cells Associated Genes Participated in Myocarditis by Qiang Gong, Jianfeng Huang, Qicai Wu

“…The purpose of our study was to investigate the gene and single-cell signature to explore the involvement of immune cells in myocarditis. Gene expressions merged from GSE35182 and GSE35182 datasets were subjected to differential expression gene (DEG) analysis and PPI network construction. …”
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RNA-Binding Proteins and Alternative Splicing Genes Are Coregulated in Human Retinal Endothelial Cells Treated with High Glucose by Hongran Zhao, Hui Kong, Bozhao Wang, Sihui Wu, Tianran Chen, Yan Cui

“…A total of 2320 differentially expressed genes (DEGs) were identified, including 1228 upregulated genes and 1092 downregulated genes. …”
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Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke. by Meimei Xu, Shan Yuan, Xing Luo, Mengsi Xu, Guangze Hu, Zhe He, Xinyuan Yang, Rui Gao

“…Long non-coding RNAs (lncRNAs) are among the most abundant types of non-coding RNAs in the genome and exhibit particularly high expression levels in the brain, where they play crucial roles in various neurophysiological and neuropathological processes. …”
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Concept, Framework, and Data Model for Geographical Soundscapes by Xiu Lu, Guannan Li, Xiaoqing Song, Liangchen Zhou, Guonian Lv

“…The soundscape in the real environment is fully expressed and described. This study provides a new research direction for soundscapes from a geographical perspective and provides guidance for urban planning and landscape design.…”
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<i>Ex Vivo</i> Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study by Arijita Sarkar, Matthew C. Gallo, Jennifer A. Bell, Cory K. Mayfield, Jacob R. Ball, Mina Ayad, Elizabeth Lechtholz-Zey, Stephanie W. Chang, Osamu Sugiyama, Denis Evseenko, Jay R. Lieberman

“…Gene therapy treatment induced a more robust chondrogenic response, as well as a decrease in the proportion of fibroblasts and the expression of profibrotic pathways. Additionally, gene therapy was associated with an anti-inflammatory microenvironment; macrophages expressing canonical anti-inflammatory markers were more common in the gene therapy group. …”
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Isolation, Characterization, and Safety Evaluation of Human Skin-Derived Precursors from an Adherent Monolayer Culture System by Ru Dai, Wei Hua, Wei Chen, Lidan Xiong, Li Li, Yiming Li

“…Methods. tSKPs generated from our adherent monolayer culture system were investigated for protein expression and differentiation capacity. The aggregated cells and the proliferative cells within tSKP spheres were detected by mix-culturing FBs expressing two different fluorescent proteins and BrdU- or EdU-positive cells, respectively. …”
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Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker by Hang Yi, Yiwen Lin, Yutong Li, Yeqi Guo, Ligong Yuan, Yousheng Mao

“…B4GALNT1 is a key enzyme in ganglioside biosynthesis. B4GALNT1 expression is linked to tumorigenesis and the prognosis of tumor patients. …”
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Diagnostic Value of Cytokeratin 17 during Oral Carcinogenesis: An Immunohistochemical Study by Sirima Sanguansin, Theerachai Kosanwat, Rachai Juengsomjit, Sopee Poomsawat

“…CK17 expression in these tissues was compared with those of normal oral mucosa (NOM). …”
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Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway by Lemei Hu, Changqing Zheng, Ying Kong, Zhiqing Luo, Fengzhang Huang, Zhigang Zhu, Quhuan Li, Ming Liang

“…We screened 84 differentially expressed genes (DEGs) and performed the functional enrichment analysis. …”
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Role of Peroxisome Proliferator-Activated Receptor β/δ and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells by Jeffrey D. Coleman, Jerry T. Thompson, Russell W. Smith, Bogdan Prokopczyk, John P. Vanden Heuvel

“…Matrix remodeling proteinases are frequently over-expressed in pancreatic cancer and are involved with metastasis. …”
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Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat by François Brial, Aurélie Le Lay, Claude Rouch, Edouard Henrion, Mathieu Bourgey, Guillaume Bourque, Mark Lathrop, Christophe Magnan, Dominique Gauguier

“…Abstract Brain regions drive multiple physiological functions through specific gene expression patterns that adapt to environmental influences, drug treatments and disease conditions. …”
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Dysregulation of c-Jun (JUN) and FBJ murine osteosarcoma viral oncogene homolog B (FOSB) in obese people and their predictive values for metabolic syndrome by Chenxi Yang, Yi Chen, Guangfeng Tang, Tongtong Shen, Li Li

“…This study aimed to identify new biomarkers for predicting MetS and provide a novel diagnostic approach. Herein, the expression profiles of c-Jun (JUN) and FBJ murine osteosarcoma viral oncogene homolog B (FOSB) in individuals with obesity and patients with MetS from the Gene Expression Omnibus database. …”
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The Efficacy of Fecal Microbiota Transplantation in Experimental Autoimmune Encephalomyelitis: Transcriptome and Gut Microbiota Profiling by Sanwang Wang, Hongliang Chen, Xin Wen, Jingjing Mu, Mingyue Sun, Xiaowen Song, Bin Liu, Jinbo Chen, Xueli Fan

“…Gut microbiota alteration in the gut and differentially expressed genes (DEGs) in the spinal cord were analyzed through 16S rRNA and transcriptome sequencing. …”
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