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2721
Identification and validation of hub gene TNFAIP6 of fibroblast-like synoviocytes in rheumatoid arthritis
Published 2025-02-01“…Methods Four independent synovial tissue microarray transcriptome sequencing datasets and one single cell sequencing dataset were downloaded from the Gene Expression Omnibus (GEO) database, and the hub gene of RA fibroblast-like synovial cells was identified by differential gene analysis, weighted gene co-expression network analysis (WGCNA) and single-cell sequencing data analysis. …”
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2722
Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges
Published 2025-01-01“…Methods To identify the midgut-expressed ABC transporters, the mosquitoes were challenged with a mixture of gram-negative (Escherichia coli) and gram-positive (Micrococcus luteus) bacteria, and the expression of all ABC transporters was analysed with PCR using gene-specific primers. …”
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2723
Plastin Family of Actin-Bundling Proteins: Its Functions in Leukocytes, Neurons, Intestines, and Cancer
Published 2012-01-01“…Three isoforms have been identified in mammals. T-plastin is expressed in cells from solid tissues, such as neurons in the brain. …”
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2724
Insights into the diverse roles of the terminal oxidases in Burkholderia cenocepacia H111
Published 2025-01-01“…In this study, we identified six terminal oxidases of B. cenocepacia H111 and constructed reporter strains to monitor their expression in different environments. While the heme-copper oxidase aa 3 (cta) was constitutively expressed, the bd-1 oxidase (cyd) was induced under oxygen-limited growth conditions. …”
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2725
CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens
Published 2025-02-01“…We thus generated a non-signaling CD32B1 mutant lacking the ITIM motif (termed ITIM-less CD32B1, or ILCD32B1) and successfully expressed it in human T cells which normally do not express this FcR. …”
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2726
A synthetic chronogenetic gene circuit for programmed circadian drug delivery
Published 2025-02-01“…Once implanted in vivo, the constructs expressed circadian rhythms and entrained to daily light cycles, producing daily increases in biologic drug at the peak of Per2 expression. …”
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2727
Toll-Like Receptors in Natural Killer Cells and Their Application for Immunotherapy
Published 2020-01-01“…In this review, we will discuss the expression and cellular function of TLRs in NK cells and also introduce some therapeutic applications of TLR agonists for NK cell-mediated immunotherapy.…”
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2728
Species-Related Differences in the Proteome of Rat and Human Pancreatic Beta Cells
Published 2015-01-01“…Human cells also expressed more heat shock proteins and radical scavenging systems: apart from SOD2, they expressed high levels of H2O2-scavenger peroxiredoxin 3 (PRDX3), confirmed by microarray, Western blotting, and microscopy. …”
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2729
Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity
Published 2012-01-01“…CD44, a hyaluronic acid receptor, is one of the most commonly studied surface markers, which is expressed by almost every tumour cell. CD24, a heat stable antigen, is another surface marker expressed in many tumour types. …”
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2730
Lysosome-related proteins may have changes in the urinary exosomes of patients with acute gout attack
Published 2025-01-01“…Compared with the ID group, the expression of Cathepsin Z (CTSZ) and AP-1 complex subunit beta-1 (AP1B1) was increased, while the expression of Lysosome-associated membrane glycoprotein 2 (LAMP2) was decreased in AD group. …”
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2731
Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment.
Published 2025-01-01“…RT-qPCR analysis confirmed that the high-risk CRLs and CRGs were highly expressed in GBM cells compared to normal astrocytes. …”
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2732
Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.
Published 2025-02-01“…RNAseq analysis and basal, luminal, and epithelial-mesenchymal transition (EMT) marker expression revealed distinct patterns; certain cell lines expressed predominantly basal or luminal markers while others demonstrated mixed expression. …”
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2733
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning
Published 2025-01-01“…Additionally, the application of Weighted Gene Co‐expression Network Analysis (WGCNA) was utilized to differentiate modules consisting of co‐expressed genes and conduct clustering analysis. …”
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2734
GGT5 Is an Independent Prognostic Biomarker in Stomach Adenocarcinoma
Published 2022-01-01“…Gamma-glutamyltransferase 5 (GGT5) is expressed in different cancers and its role in cancers remains unclear. …”
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2735
Unveiling gratitude in Javanese Muslim hajatan traditions: Cultural wisdom and social cohesion in the midst of modernization
Published 2025-01-01“…The hajatan tradition within the Javanese Muslim community is a culturally rich practice imbued with deep social and spiritual meaning, serving as a means to strengthen social bonds, preserve cultural values, and express gratitude to God, nature, and fellow human beings. …”
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2736
Overexpression of Delayed Rectifier K+ Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure
Published 2012-01-01“…Leukocytes, such as lymphocytes and macrophages, predominantly express delayed rectifier K+ channels (Kv1.3), and the channels play crucial roles in the activation and proliferation of the cells. …”
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2737
NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration
Published 2025-01-01“…NIPA-like proteins (NIPAs) are expressed in a variety of cancer types, yet the role of NIPAL1 in cancer remains unclear. …”
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2738
Pengaruh Hormon Androgen terhadap Ekspresi Gen CD52 di Epididimis Mencit (Mus musculus)
Published 2020-08-01“…Androgen has an important role in regulation epididymal sperm maturation Epididymal sperm maturation is occurs via interactions between sperm and proteins secreted by epididymal genes that are specifically expressed in a region-specific manner. Mice CD52 exhibited expression in all regions in epididymis. …”
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2739
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment
Published 2025-03-01“…The correlation between LAMB1 expression and clinical characteristics, prognosis was explored. …”
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2740
LncRNA GAS5 reduces blood glucose levels and alleviates renal fibrosis in diabetic nephropathy by regulating the miR-542-3p/ERBB4 axis
Published 2025-01-01“…Methods db/db mice were injected with lncRNA GAS5 high expression or miR-542-3p low expression related vectors. …”
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