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    Clinical Features and Prognosis Analysis of Hormone Receptor-Positive, HER2-Negative Breast Cancer with Differential Expression Levels of Estrogen and Progesterone Receptors: A 10-Year Retrospective Study by Jin Liu, Mingyu Gan, Zijing Lin, Qin Deng, Juan Deng, Bin Zeng, Yanling Shi, Jia Ming

    Published 2022-01-01
    “…In the group of ER+/PR+/HER2-patients, there was no significant prognostic difference between ER-low positive and ER-high positive groups, but low PR expression was significantly associated with a worse prognosis. …”
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  6. 2406

    Evaluation of immunohistochemical expression of novel neuroendocrine marker INSM1 and histological tumor growth pattern in well-differentiated neuroendocrine tumors of the appendix: 15-year single tertiary center experience by Ali Koyuncuer, Tolga Canbak, Aylin Acar, Onur Şahin

    Published 2024-04-01
    “…Aims: The aim of this study was to determine the staining expression of INSM1 in A-WDNETs and detail the morphological tumor growth patterns. …”
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    Influence of caffeic acid and Bacillus coagulans supplementation on growth, digestive enzymes, immune response, and antioxidant gene expression in common carp (Cyprinus carpio) and its resistance to Aeromonas hydrophila infection by Seyedeh Shiva Alavinejad, Mehdi Soltani, Seyed saeed Mirzargar, Poulin Shohreh, Ali Taherimirghaed

    Published 2025-03-01
    “…Values of total protein, total immunoglobulin, lysozyme activity, and alternative complement pathway (ACH50) were higher in sera of BC and CA+BC groups than CD (P < 0.05). Additionally, expression of genes related to lysozyme, IL-1β, IL-8, TNF-α, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver tissues of treatment groups were upregulated better than CD (P < 0.05). …”
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    Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production by Michelle A.E. Brouwer, Zara Karami, Samuel T. Keating, Hedwig Vrijmoeth, Heidi L.M. Lemmers, Helga Dijkstra, Frank L. van de Veerdonk, Mihaela Lupse, Hadewych J.M. ter Hofstede, Mihai G. Netea, Leo A.B. Joosten

    Published 2025-01-01
    “…While STAT3 phosphorylation was highly induced in T cells, B cells and NK-(T) cells, STAT1 expression and IL-12p70 production were not or only slightly increased upon B. burgdorferi s.l. exposure. …”
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  11. 2411

    Produção de riscos, consumo, necropolítica e desigualdades: expressividades midiáticas da pandemia no contexto brasileiro / Risk production, consumption, necropolitics and inequalities: media expressiveness of the pandemic in the Brazilian context by Beatriz Lira de Arruda Dias, Érika de Sousa Mendonça, Juliana Catarine Barbosa da Silva

    Published 2021-01-01
    “…Este estudo objetiva analisar informações veiculadas no contexto da pandemia, buscando compreender e explicitar aspectos ancorados nas produções dos discursos, os sentidos produzidos, bem como as materialidades expressas através do comportamento de consumo e acumulação da população, suscitados pela pandemia. …”
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    Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-Associated Kaposi's Sarcoma by Cecilia Sgadari, Giovanni Barillari, Clelia Palladino, Stefania Bellino, Brunella Taddeo, Elena Toschi, Barbara Ensoli

    Published 2011-01-01
    “…Here we show that the development of angioproliferative lesions promoted in mice by combined Tat and FGF-2 associates with an increase in the levels of expression of the antiapoptotic Bcl-2 protein. Upregulation of Bcl-2 expression by combined FGF-2 and Tat occurs also in vitro, and this protects human primary endothelial cells from programmed cell death. …”
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    Increased nuclear expression of DNA damage inducible transcript 4 can serve as a potential prognostic biomarker in patients with gliomas: a study based on data mining and experimental tools by Alireza Sadeghipour, Fahimeh Fattahi, Zahra Madjd, Fatemeh Tajik, Farnoosh Sedaghati, Leili Saeednejad Zanjani

    Published 2025-02-01
    “…Abstract Introduction DNA damage-inducible transcript 4 (DDIT4), induced under cellular stress conditions, has been implicated in malignancies due to its abnormal expression patterns. Materials and methods The expression of DDIT4 at the mRNA level and its potential role as a prognostic biomarker in gliomas were analyzed using the GEPIA tool. …”
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    Chia (<i>Salvia hispanica</i>) Seed Oil Modulates the Haemato-Immunological Response, Antioxidative Status and Cytokine Gene Expression of Tropical Freshwater Teleost, <i>Labeo rohita</i> by Sanjay Kumar Gupta, Rajan Gupta, Akruti Gupta, Md Javed Foysal, Kishore Kumar Krishnani

    Published 2025-01-01
    “…The present investigation attempts to evaluate the impact of the dietary inclusion of chia (<i>Salvia hispanica</i>) seed oil (CSO) on the indices of haemato-immunology, metabolic enzymes, and expression of immune-responsive cytokine genes in <i>Labeo rohita</i> (rohu) fingerlings. …”
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    Lactobacillus reuteri LR1 Improved Expression of Genes of Tight Junction Proteins via the MLCK Pathway in IPEC-1 Cells during Infection with Enterotoxigenic Escherichia coli K88 by Hongbo Yi, Li Wang, Yunxia Xiong, Zhilin Wang, Yueqin Qiu, Xiaolu Wen, Zongyong Jiang, Xuefen Yang, Xianyong Ma

    Published 2018-01-01
    “…In conclusion, L. reuteri LR1 had beneficial effects on epithelial barrier function consistent with increasing ZO-1 and occludin expression via a MLCK-dependent manner in IPEC-1 cells during challenge with ETEC K88.…”
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