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Emerging roles of extracellular vesicles in oral and maxillofacial areas
Published 2025-02-01“…Abstract The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body. …”
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Muscle-derived extracellular vesicles mediate crosstalk between skeletal muscle and other organs
Published 2025-01-01“…In this review, we briefly describe the biological characteristics, composition, and uptake mechanisms of EVs, particularly exosomes, comprehensively summarize the regulatory effects of SKM-EVs on the function of, which include myogenesis, muscle repair and regeneration, as well as metabolic regulation. …”
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43
Advances in the research of immunomodulatory mechanism of mesenchymal stromal/stem cells on periodontal tissue regeneration
Published 2025-01-01“…In recent years, due to the good tissue regeneration ability, the research on Mesenchymal stromal/stem cells (MSCs) and MSC-derived exosomes has been gradually deepened, especially its ability to interact with the microenvironment of the body in the complex immunoregulatory network, which has led to many new perspectives on the therapeutic strategies for many diseases. …”
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Mesenchymal stem cell therapy as a game-changer in liver diseases: review of current clinical trials
Published 2025-01-01“…Summary Chronic liver diseases, including cirrhosis and liver failure, remain formidable challenges due to their complex progression and limited therapeutic options. …”
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Data-driven prediction of critical diameter for deterministic lateral displacement devices: an integrated DPD-ML approach
Published 2025-12-01“…This leads to significant economic and time costs, while the complexity of instruments and algorithms further raises the barrier for DLD design and optimization. …”
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The role of ultrasound combined with water bath in the establishment of animal models of rat urethral stricture
Published 2025-01-01“…Urethral stricture presents a complex challenge in urology, often requiring invasive treatment modalities. …”
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Cancer stem cells and tumor-associated macrophages as mates in tumor progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interacti...
Published 2025-02-01“…Here, we aim to elucidate the most recent insights on CSCs biology and their complex interactions with TME immune cells, specifically TAMs, tracing an exhaustive scenario from the primary tumor to metastasis formation.…”
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Potential and development of cellular vesicle vaccines in cancer immunotherapy
Published 2025-01-01“…This vaccine has a unique structure that can integrate antigen and adjuvant carriers to improve the delivery efficiency and immune activation ability, which brings new ideas for cancer vaccine design. Tumor exosomes carry antigens and MHC-peptide complexes, which can provide tumor antigens to antigen-processing cells and increase the chances of recognition of tumor antigens by immune cells. …”
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Enhancing precision in cancer treatment: the role of gene therapy and immune modulation in oncology
Published 2025-01-01“…Advances in non-viral delivery systems, such as lipid nanoparticles (LNPs) and exosomes, are improving the safety and efficacy of gene therapies. …”
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