Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer by Yen-Han Tseng, Trieu Thi My Tran, Jinghua Tsai Chang, Yu-Tang Huang, Anh Thuc Nguyen, Ian Yi‑Feng Chang, Yi-Tung Chen, Hao-Wen Hsieh, Yue-Li Juang, Peter Mu-Hsin Chang, Tzu-Yi Huang, Ying-Chih Chang, Yuh-Min Chen, Hsuan Liu, Chi-Ying F. Huang

Get full text

Saturated hydraulic conductivity and steady-state infiltration rate database for Brazilian soils by Marta Vasconcelos Ottoni, Wenceslau Geraldes Teixeira, Aline Mari Huf dos Reis, Letícia Guimarães Pimentel, Luciana Rodrigues Souza, Jackson Adriano Albuquerque, Valdinar Ferreira Melo, Karina Maria Vieira Cavalieri-Polizeli, José Miguel Reichert, João Herbert Moreira Viana, Ademir Fontana, Lucas de Castro Medrado, Glenio Guimarães Santos, Luís Gustavo Henriques do Amaral, Lúcia Helena Cunha dos Anjos, José Coelho de Araújo Filho, Silvio Barge Bhering, Gabrielle Fernandes de Brito, Pedro Gomes de Campos do Valle, Pablo Nieto Campos, Adriana Monteiro da Costa, Jean Dalmo de Oliveira Marques, Alba Leonor da Silva Martins, Michele Bruna de Souza do Nascimento, Norberto Cornejo Noronha, Ricardo Duarte de Oliveira, Jeane Cruz Portela, Milson Evaldo Serafim, Marlen Barros e Silva, Sueli Rodrigues, Wilk Sampaio de Almeida, Margareth Lopes de Moraes, Nilton Curi

“…This database was named Ksat-SSIR-DB. One analysis of the Ksat-SSIR-DB aimed to evaluate its coverage in Brazilian territory and in different soil groups. …”
Get full text

Hypertension and Dementia in the Elderly: The Leisure World Cohort Study by Annlia Paganini-Hill

“…Dementia status was determined from in-person evaluations, followup questionnaires, hospital data, and death certificates. …”
Get full text

Providing a model of consumer behavior in creating brand attachment with an emphasis on the packaging component of food industry companies by maziar Ghasemzadeh Sangroudi, karim hamdi, SHADAN VAHABZADEH MUNSHI

“…In this research, thematic analysis method was used to analyze qualitative data. …”
Get full text

Postoperative radiotherapy improves survival in completely resected non-small cell lung cancer with pathologic N2 stage IIIA and positive lymph node count greater than one: a SEER-... by Diyang Zhu, Yuanyuan Xiao, Yuanyuan Xiao, Shancheng He, Shancheng He, Baochang Xie, Baochang Xie, Wenqi Zhao, Wenqi Zhao, Yuhui Xu

“…This study seeks to evaluate the effect of postoperative radiotherapy (PORT) on overall survival (OS) and cancer-specific survival (CSS) in patients with resected pathologic N2 (pN2) stage IIIA NSCLC.MethodsData from the Surveillance, Epidemiology, and End Results Program (SEER) 17 registry (2010–2019) were analyzed. …”
Get full text

B7-H3 CAR-T cell therapy combined with irradiation is effective in targeting bulk and radiation-resistant chordoma cancer cells by Kun Wang, Gianpietro Dotti, Soldano Ferrone, Yufeng Wang, Yin P Hung, Tao Ma, Giulia Cattaneo, Xinhui Wang, David O Osei-Hwedieh, Tara A Walhart, Joseph H Schwab

Get full text

An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study by Guanghao Liu, Shixiang Zheng, Jun He, Zi-Mei Zhang, Ruoqiong Wu, Yingying Yu, Hao Fu, Li Han, Haibo Zhu, Yichang Xu, Huaguo Shao, Haidan Yan, Ting Chen, Xiaopei Shen

“…We developed a simplified risk-stratified early forewarning model for SS based on the weight of evidence and logistic regression, which was compared with multi-feature complex models, and clinical characteristics among risk groups were evaluated. ResultsUsing only vital signs and rapid arterial blood gas test features according to feature importance, we constructed the Septic Shock Risk Predictor (SORP), with an area under the curve (AUC) of 0.9458 in the test set, which is only slightly lower than that of the optimal multi-feature complex model (0.9651). …”
Get full text

Efficacy, safety and cost-effectiveness of obinutuzumab in patients with follicular lymphoma: a rapid review by Chao Wang, Yunzhuo Dong, Peng Men, Ruixia Zhang, Ying Xiao, Yishan Bu, Yinpeng Qin, Xinran Zhang, Qianqian Dou, Yiheng Yang, Huier Gao, Yi Zhang

“…The literature was screened based on predefined inclusion and exclusion criteria, and data were meticulously extracted and synthesized by two authors. …”
Get full text

Leucine-rich alpha-2 glycoprotein in combination with C-reactive protein for predicting endoscopic activity in Crohn’s disease: a single-centre, cross-sectional study by Yoshiaki Takada, Hiroki Kiyohara, Yohei Mikami, Masataka Taguri, Ryoya Sakakibara, Yasuhiro Aoki, Kosaku Nanki, Takaaki Kawaguchi, Yusuke Yoshimatsu, Shinya Sugimoto, Tomohisa Sujino, Kaoru Takabayashi, Naoki Hosoe, Haruhiko Ogata, Motohiko Kato, Yasushi Iwao, Nobuhiro Nakamoto, Takanori Kanai

Get full text

Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion by Zheng Huang, Xialin Li, Weihong Yi, Junfeng Gong, Yue Zhou, Yu Tang

“…Univariate tests (chi-square, Student’s t-test, and analysis of variance) were employed to compare factors between groups. …”
Get full text

Protocol for Home-Based Solution for Remote Atrial Fibrillation Screening to Prevent Recurrence Stroke (HUA-TUO AF Trial): a randomised controlled trial by Jing Tan, Yan Liang, Yong Liu, Wei Jiang, Duo Huang, Ning Tan, Chung-Wah Siu, Jo Jo Hai, Xiaoyu Huang, Jianfeng Ye, Ji-yan Chen, Chun Ka Wong, Mi Zhou, Li-Xue Yin, Ming-Liang Zuo, Kui Kai Lau, Zhen Lei, Yingqing Feng, Bryan P Yan, Wen-Sheng Yue, Wen-Jun Zhang, Yuk-Ming Lau, Hin-Wai LUI, Koon-Ho Chan, Toi Meng Mok, Weng-Chio Tam, Kun-Chong Tam, Xiuhua Feng, Xiaofei Jiang, Guanming Tan, Mario Alberto Evora

“…The objective of the study was to explore the use of long-term home-based ECG monitoring for AF detection and stroke prevention in patients with a history of stroke.Methods and analysis This prospective, randomised, open-label trial with blinded endpoint adjudication aimed to evaluate the efficacy of long-term home-based ECG monitoring for AF detection and stroke prevention in a 24-month period. …”
Get full text

Effect of EGCG–Methacrylate-Functionalized Resin Infiltrant on White Spot Lesions: An In Vitro Study by Karin Landmayer, Bruna de Oliveira Iatarola, Talita Portela Pereira, Raquel Shimizu Mori, Alyssa Teixeira Obeid, Mariele Vertuan, Daniela Alvim Chrisostomo, Ana Carolina Magalhães, Lulwah Alreshaid, Paulo Henrique dos Santos, Anuradha Prakki, Luciana Fávaro Francisconi-dos-Rios

“…The color was determined with a spectrophotometer. Data were statistically evaluated (<i>p</i> = 0.05). …”
Get full text

Analyzing the serum biochemical factors that influence early neurological deterioration in ischemic Stroke patients and developing a nomogram prediction model by Xiaoni Zhan, Yunyun Xu, Rongrong Ma

“…Methods: General clinical data from 220 IS patients treated between December 2022 and November 2023 were collected for observation. …”
Get full text

Influence of sedentary behavior on sleep quality in postmenopausal women in high-altitude regions of China: a cross-sectional study by Rilang Leng, Ailin Guo, Guoping Qian, Sujie Mao

“…Data analysis encompassed descriptive statistics, correlation analysis, multiple linear regression, and subgroup analyses.ResultsAmong the 151 participants (mean age 58.5 years), sedentary behavior was positively correlated with poorer sleep quality (r = 0.36, p &lt; 0.001). …”
Get full text

Low handgrip strength with asymmetry is associated with elevated all-cause mortality risk in older Chinese adults with abdominal obesity. by Ling Wei, Binyou Wang, Yilin Wang

“…Logistic regression analysis was used to evaluate the relationship between AO, abnormal HGS and mortality risk.…”
Get full text

The impact of KRAS mutations on the tumour microenvironment and treatment response in non-small cell lung cancer by Guomin Gu, Chunling Liu, Yan Yang, Yan Zhao, Xiaodan Zhu, Gang Sun

“…DEGs between KRAS mutations and wild type were identified, and enrichment analysis was performed. The differences in immune cell infiltration between the 2 groups were evaluated using ssGSEA, and TIDE scoring, immune checkpoint therapy sensitivity, and drug treatment sensitivity analysis were performed. …”
Get full text

Effects of environmental factors on the phenotypic traits and seed element accumulation of wild Elymus nutans in Tibet by Jianting Long, Xianlei Gao, Yanjun Miao

“…Cluster analysis categorized the 25 samples of Elymus nutans into four distinct groups, each exhibiting significant differences in height and leaf length. …”
Get full text

Socioeconomic and behavioral factors of hypertension among Indian tribal population: Evidence from national family health survey 5. by Bodhi Sri Vidya Vennam, Sai Sushma Kuppli, Jayanta Kumar Bora, Soumya Swaroop Sahoo, Chaitanya Gujjarlapudi, Devi Madhavi Bhimarasetty, Ganga Nagamani Nerusu, Sonu Goel

“…Chi-square test and the Cochran-Armitage trend test were employed to evaluate the association. Complex samples logistic regression analysis was conducted using clusters and sampling weights. …”
Get full text

Comparison of Instrumental Variable Methods With Continuous Exposure and Binary Outcome: A Simulation Study by Shunichiro Orihara, Atsushi Goto

Get full text

Condition of the autonomic nervous system during the 'sit-stand-sit' orthostatic test in university students in areas of military conflict in Ukraine by Igor Vypasniak, Sergii Iermakov, Lyudmila Shesterova

“…The third category had the most heart rate variability, potentially indicating inadequate stress adaptation and possible cardiovascular health risks. Conclusions. Analysis of the data reveals that physical preparedness markedly affects heart and blood vessel system reactions in both genders. …”
Get full text