Cardiovascular risk and mortality in men receiving testosterone replacement therapy for Klinefelter syndrome in Denmark: a retrospective cohort studyResearch in context by Simon Chang, Lars Pedersen, Anne Skakkebæk, Agnethe Berglund, Claus H. Gravholt

“…We similarly identified a comparison cohort of 50,150 men from the background population matched on month and year of birth. Median age at entry for KS-TRT was 31.1 years (interquartile range; 19.9–40.0) and median follow-up time was 12.9 years (interquartile range; 7.5–20.7). …”
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Nasal microbial diversity is associated with survival in piglets infected by a highly virulent PRRSV-1 strain by Pau Obregon-Gutierrez, Martí Cortey, Gerard E. Martín-Valls, Hepzibar Clilverd, Florencia Correa-Fiz, Virginia Aragón, Enric Mateu

“…To deepen the analysis, we added samples taken from piglets before the outbreak as well as from the sows giving birth to piglets under study. Results Piglets that survived the PRRSV-1 outbreak reported a more diverse and different nasal microbiota at three weeks of age compared to piglets dying, which was highly related with the litter of origin and the sow of the piglets. …”
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Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021 by Xi Chen, Xi Chen, Dandan Ma, Hangyu Li, Yilin Liu, Guixing Xu, Xinyu Deng, Qi Li, Junqi Li, Hui Pan

“…The period ratio rate of incidence and mortality declined with the calendar year, and the corrections between birth cohort and the risk of incidence and mortality were negative. …”
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Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database by Aleksandar Radunović, Carol Coupland, Julia Hippisley-Cox, Christopher J McDermott, Tom A Ranger, Judith Burchardt, Xue W Mei

“…The nested case–control data set comprised of 6437 cases of MND diagnosed between January 1998 and December 2019, matched by year of birth, gender, general practice and calendar year to 62 003 controls.Main outcome measures Clinically recognised symptoms and signs of MND prior to diagnosis and symptoms and factors which are relevant in primary care setting.Results This study identified 17 signs and symptoms that were independently associated with MND diagnosis in a multivariable analysis. …”
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Association of sex and aspirin use with postoperative bleeding in patients with lower extremity long bone fractures by Michael Fisher, Kristin Salottolo, David Bar-Or, Matthew Carrick, Kaysie L Banton, Robert Madayag, Chad M Corrigan

“…However, biological sex at birth (M/F) was a significant effect modifier (interaction p=0.04). …”
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The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

“…The intervention started within 72 h following birth and continued for eight weeks postpartum. The intervention group received two daily capsules containing dried basil leaf powder, while the control group received 500 mg of starch. …”
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Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 by Tayfun VURAL, Burak BAYRAKTAR, Suna YILDIRIM KARACA, Ozan ODABAS, Nisel YILMAZ, Pınar SAMLIOGLU, Mehmet OZEREN

“…Both groups are quite similar in terms of maternal [respiratory support, COVID-19-related treatment, and intensive care unit (ICU) admission], perinatal (preterm delivery, preterm premature rupture of membrane, preeclampsia, and mode of delivery), and neonatal outcomes [birth weight, Apgar scores, neonatal ICU (NICU) admission]. …”
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Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Waleed T Batais, Nada O Taher, Abeer K Alhindi, Abdullah A Ghaddaf, Anas Alamoudi, Sarah A Al-Ghamdi, Jumanah J Homsi, Hashem S Almarzouki, Mansour A Qurashi

“…Objective Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in preterm infants with low birth weight. The efficacy and safety of prophylactic agents, including vitamin A, propranolol and lipids, in reducing ROP incidence remain unclear. …”
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Individual and community level maternal factors for zero-dose children in Ethiopia using mini-EDHS 2019: a mixed effects model by Anteneh Kassa Yalew, Werkneh Melkie Tilahun, Meron Asmamaw Alemayehu, Tigabu Kidie Tesfie, Muluken Chanie Agimas, Mekuriaw Nibret Aweke, Worku Necho Asferie, Moges Tadesse Abebe

“…Women with no antenatal care follow-up (adjusted OR (AOR)=1.55, 95% CI 1.02 to 2.35), uneducated women (AOR=1.47, 95% CI 1.11 to 1.95), women who gave birth at home (AOR=1.39, 95% CI 1.04 to 1.86), women who had poor wealth index (AOR=2.15, 95% CI 1.62 to 2.85) and women from low proportions of community media exposure (AOR=1.39, 95% CI 1.13 to 1.71) were the risk factors for zero-dose children in Ethiopia.Conclusion Compared with previous studies, the prevalence of zero-dose children was low in Ethiopia. …”
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Economic and clinical burden associated with respiratory syncytial virus and impact of universal immunization with nirsevimab in Italy by Andrea Marcellusi, Chiara Bini, Barbara Muzii, Samira Soudani, Alexia Kieffer, Matthieu Beuvelet, Elena Bozzola, Fabio Midulla, Eugenio Baraldi, Paolo Bonanni, Sara Boccalini, Luigi Orfeo

“…Objectives: To describe the seasonal respiratory syncytial virus (RSV) burden in Italy considering the current prophylaxis strategy with palivizumab recommended only for high-risk infants (representing only 4.4% of an estimated birth cohort) and to evaluate the potential benefits of a new prophylaxis strategy targeting all infants with nirsevimab. …”
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Trends and factors associated with delays in the first prenatal consultation in Guinea by Tiany Sidibe, Mamadou Dioulde Balde, Sadan Camra, Ramata Diallo, Bienvenu Salim Camara, Karifa Kourouma, Madeleine Toure, Kaba Saran Keita, Fanta Barry, Maimouna Balde

“…The study included women aged 15-49 years who gave birth in the five years prior to the surveys and had at least one ANC visit for their last child. …”
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Pengaruh Pemijatan Perineum pada Primigravida terhadap Kejadian Ruptur Perineum saat Persalinan di Bidan Praktek Mandiri di Kota Bengkulu Tahun 2014 by Wewet Savitri, Ermawati ., Elda Yusefni

“…As many as 85% of women give birth vaginally may experience rupture of the perineum. …”
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Exploring the Role of the Pharmacist in the Prevention and Management of Hypertensive Disorders in Pregnancy in Ashanti Region, Ghana by Pauline Boachie‐Ansah, Berko Panyin Anto, Afia Frimpomaa Asare Marfo, Edward Tieru Dassah, Morrison Asiamah, Ivan Eduku Mozu, Nana Ofori Adomako, Kwaku Gyamfi Oppong

“…ABSTRACT Hypertensive disorders in pregnancy (HDPs) are a leading cause of poor maternal and birth outcomes worldwide. Prompt management of these disorders is usually recommended to optimize outcomes. …”
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Obesity in pregnancy: infant health service utilisation and costs on the NHS by Ronan A Lyons, Ashrafunnesa Khanom, Sinead T Brophy, Kelly L Morgan, Muhammad A Rahman, Rebecca A Hill

“…Costs are calculated as cost of the infant (no maternal costs considered) and are related to health service usage from birth to age 1 year.Results A strong association existed between healthcare usage cost and BMI (p<0.001). …”
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Utilizing machine-learning techniques on MRI radiomics to identify primary tumors in brain metastases by W. L. Yang, W. L. Yang, X. R. Su, S. Li, K. Y. Zhao, Q. Yue

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An Attenuated Cytomegalovirus Vaccine with a Deletion of a Viral Chemokine Gene Is Protective against Congenital CMV Transmission in a Guinea Pig Model by Michael P. Leviton, Juan C. Lacayo, K. Yeon Choi, Nelmary Hernandez-Alvarado, Andrew Wey, Mark R. Schleiss

“…Immunization protected against DNAemia (1/15 in vaccine group versus 12/13 in the control group, P<0.01). Mean birth weights were significantly higher in pups born to vaccinated dams compared to controls (98.7 g versus 71.2 g, P<0.01). …”
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A Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage by Tatsuya Akitomo, Noriko Niizato, Ami Kaneki, Masashi Ogawa, Taku Nishimura, Mariko Kametani, Momoko Usuda, Yuko Iwamoto, Chieko Mitsuhata, Ryota Nomura

“…She started enzyme replacement therapy 6 days after birth, and genetic analysis later confirmed the diagnosis of HPP. …”
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APPRENDERE E INSEGNARE LA LINGUA DEI SEGNI ITALIANA (LIS) COME L2-M2 ALL’UNIVERSITÀ: OSSERVAZIONE E ANALISI DI UN PANORAMA ETEROGENEO by Emilia Terziani

“…This work aims to show an overview of Italian Sign Language learning and teaching in the Italian university context starting from the circumstances that favored the birth of the first LIS courses in some Italian universities, among whom Scuola Superiore di Lingue Moderne per Interpreti e Traduttori (SSLMIT) in Trieste and Università di Teramo. …”
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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques by Joanna Zikos, Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko, Ala M. Shaqra, Celia A. Schiffer, Koen K. A. Van Rompay, Jonah B. Sacha, Diogo M. Magnani

“…Further, a single dose of leronlimab-PLS led to complete CCR5 receptor occupancy in mothers and newborns for almost a month after birth. These findings support the optimization of FcRn interactions in mAb therapies designed for administration during pregnancy.…”
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Essential newborn care practices in selected public health facilities using observation of 2603 normal deliveries in Uttar Pradesh, India by James Blanchard, Marissa L Becker, Ties Boerma, Ravi Prakash, Shajy Isac, Bidyadhar Dehury, Banadakoppa Manjappa Ramesh, Vasanthakumar Namasivayam, John Anthony, Nihal Hasan, Prakash P Javalkar

“…We defined ENBC practice as both cord care and initiation of breastfeeding within 1 hour of birth were practiced in normal deliveries by the staff nurse. …”
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