Assessing the suitability of sites near Pine Island Glacier for subglacial bedrock drilling aimed at detecting Holocene retreat–readvance by J. S. Johnson, J. Woodward, I. Nesbitt, K. Winter, S. Campbell, K. A. Nichols, R. A. Venturelli, S. Braddock, B. M. Goehring, B. Hall, D. H. Rood, G. Balco, G. Balco

“…<p>Unambiguous identification of past episodes of ice sheet thinning below the modern surface and grounding line retreat inboard of present requires recovery and exposure dating of subglacial bedrock. …”
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Acute respiratory tract infections during the first 6 years of life – results from the German birth cohort study LoewenKIDS by Bianca Klee, Sophie Diexer, Susan Langer, Cornelia Gottschick, Carla Hartmann, Nadine Glaser, Johannes Horn, Evelyn Dorendorf, Heike Raupach-Rosin, Lamiaa Hassan, Nicole Rübsamen, Kristin Maria Meyer-Schlinkmann, Carlos A. Guzman, Valerie Heselich, Eva Battin, Thomas Pietschmann, Dietmar H. Pieper, Mathias Pletz, Peggy Riese, Stephanie Trittel, Saskia Thies, Constantin von Kaisenberg, Frank Dressler, Florian Guthmann, Carsten Oberhoff, Ralf L. Schild, Andre Karch, Rafael Mikolajczyk

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Familial Mediterranean fever in Romania: a case report and literature review by Alin Iuhas, Alin Iuhas, Cristian Marinău, Cristian Marinău, Larisa Niulaș, Larisa Niulaș, Zsolt Futaki, Andreea Balmoș, Andreea Balmoș, Kinga Kozma, Kinga Kozma, Mirela Indrieș, Mirela Indrieș, Cristian Sava, Cristian Sava

“…We report a 7-year-old Romanian girl, from a non-classical ethnic background, with recurrent febrile episodes and elevated inflammatory markers. Genetic testing confirmed a homozygous MEFV c.2082G&gt;A (p.Met694Ile) variant. …”
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Molecular Patterns of MEFV Gene Mutations in Egyptian Patients with Familial Mediterranean Fever: A Retrospective Cohort Study by Amal R. Mansour, Ayman El-Shayeb, Nihal El Habachi, Mohamad A. Khodair, Doaa Elwazzan, Nermeen Abdeen, Marwa Said, Riham Ebaid, Noha ElShahawy, Amr Seif, Nadia Zaki

“…The most commonly encountered gene mutations in heterozygous and homozygous groups were E148Q (38.6%), M694I (18.1%), and V726A (15.8%). The most commonly encountered gene mutations in the compound heterozygous groups were E148Q+M694I observed in 20.6% of the patients, followed by M694I+V726A and M6801+V726A found in 18.9% and 11.4 %, respectively. …”
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Assessment of the efficacy of on-demand tegoprazan therapy in gastroesophageal reflux disease through a randomized controlled trial by Sun Hyung Kang, Hee Seok Moon, Jae Kyu Sung, Sun Moon Kim, Ki Bae Kim, Seung Woo Lee, Young Sin Cho, Ki Bae Bang, Kyung Ho Song

“…In the tegoprazan group, 26.2% (182/694) of those with episodes experienced symptom improvement within 30 min, which is a significantly higher proportion compared to 16.1% (104/646) in the esomeprazole group. …”
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A Time-motion Comparison of Itemized Treatment Costs in First and Second In Vitro Fertilization Attempts: A United Kingdom Fertility Centre Experience by Christopher A. Jones, Olivia J. Carpinello, Dev Kumar, Louis G. Keith, Renju S. Raj, E. Scott Sills

“…For second IVF cycles, patients spent significantly less time with staff compared to their first IVF cycle (6.94±2.44 hrs; p<0.05), corresponding to £257.53±90.77 in personnel cost. …”
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The role of the KIBRA and APOE genes in developing spatial abilities in humans by A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, R. N. Mustafin, Z. R. Takhirova, S. B. Malykh, M. M. Lobaskova, T. N. Tikhomirova, E. K. Khusnutdinova

“…The analysis of gene-environment interactions revealed that nicotine smoking (β = 3.74; p = 0.010) and urban/rural residency in childhood (β = –6.94; p = 0.0002) modulated the association of KIBRA rs17070145 and АРОЕ (rs7412, rs429358) gene variants with individual differences in mental rotation, respectively. …”
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