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MP-LLAVRec: an agricultural product recommendation algorithm based on LLAVA and user modal preference
Published 2025-01-01“…It consisted of three main components: (1) LLAVA data enhancement, which introduced a multimodal macromodel to improve the understanding of node attributes; (2) agricultural product association relationship fusion, which constructed and improved the complex association network structure among products to ensure that the system can better understand the substitution relationship, complementary relationship, and implied consumption logic among products; (3) user modal preference feature extraction block, which deeply mined the interaction data between consumers and products, and advanced the effective user feature information from the correspondence between global user representations and local modal user representations.Results and DiscussionWe conduct experiments on a real dataset from Amazon's large-scale e-commerce platform to verify the effectiveness of MP-LLAVRec. …”
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5802
CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens
Published 2025-02-01“…To broaden the utility of this scaffold, we have also generated a new fusion protein in which the entire Fc binding domain was truncated (tILCD32B1) and replaced with a monomeric streptavidin variant, mSA2, via a CD8 hinge. …”
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5803
Estimating stomatal conductance of citrus orchard based on UAV multi-modal information in Southwest China
Published 2025-02-01“…Additionally, Gs exhibited a strong correlation with 20 cm and 40 cm soil moisture content (SMC20 and SMC40), with R2 of 0.638 and 0.606, respectively (P < 0.05). The fusion of RGB, MS, and TIR multimodal information significantly improved the accuracy of Gs estimation. …”
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5804
Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice
Published 2025-01-01“…The findings from hepatic transcription studies revealed CIDEA as an essential DEG that facilitates lipid droplet (LD) fusion and enhances de novo fatty acid synthesis from scratch in cases of hepatic steatosis, which HLSP has the potential to counteract. …”
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5805
Infectivity in full-term placenta of Zika viruses with different lipid profiles
Published 2025-02-01“…This increased infectivity was linked to enhanced fusion efficiency during the viral uncoating phase in trophoblast cells, as demonstrated using a lipophilic probe. …”
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5806
Post-traumatic pituitary stalk transection syndrome (PSTS) expeditiously manifested after a fall from a height combined with acute traumatic spinal cord injury: a rare case report...
Published 2024-08-01“…She was diagnosed as an acute traumatic spinal cord injury and underwent the operation of elective posterior spinal fusion. On postoperative day 7, the blood tests revealed considerable hyperkalemia, hyponatremia and eosinophilia. …”
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5807
YafN-YafO toxin-antitoxin system contributes to stress resistance and virulence of avian pathogenic Escherichia coli
Published 2025-02-01“…Electrophoretic mobility shift assays (EMSA) and lacZ fusion reporter assays demonstrated that YafN negatively autoregulates its own operon. …”
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5808
Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal
Published 2025-01-01“…For antibody-reactive plasma, paired peripheral blood mononuclear cells were stimulated by fusion proteins and IFN-γ cellular responses were assessed via ELISPOT.ResultsWe observed substantial levels of pre-existing cross-reactive immunity to SARS-CoV-2, stemming from prior exposure to seasonal hCoVs. …”
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5809
Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers
Published 2024-12-01“…While having a pronounced impact on NK cell killing efficacy, the capabilities of triggering antibody-dependent cellular phagocytosis or complement-dependent cytotoxicity were not significantly affected comparing the bivalent IgG-like NKCEs with cetuximab. However, the fusion of sdAbs can have a slight impact on the NK cell release of immunomodulatory cytokines, as well as on the pharmacokinetic profile of the NKCE due to unfavorable spatial orientation within the molecule architecture. …”
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5810
Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors
Published 2025-01-01“…T cell proliferation and function were detected using flow cytometry. Peptide-Fc fusion proteins were used to deplete myeloid-derived suppressor cells (MDSCs). …”
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5811
El nuevo alcance de la protección de las marcas tridimensionales en Colombia
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5812
Influence of Exposure to Different Green Rooftop Spaces on Stress Restoration of College Students
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Utility of Noninvasive Testing Before Invasive Coronary Angiography in the Assessment for Revascularization
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5818
Recommendation for the use of respiratory syncytial virus vaccines
Published 2025-02-01“…RSV is also a significant viral pathogen for adults with respiratory tract infection.Vaccines targeting the pre-fusion protein of RSV, including recombinant and mRNA vaccines, are now available. …”
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5819
Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families
Published 2025-01-01“…Among them, five novel variants, c.1153_1155del in LMNA, c.577 A > G in ACTA1, c.694T > G in MSTO1, c.5938del in LAMA2, and a rare genome fusion ogm[GRCh38] fus(X; X)(p22.31;p21.1) involving DMD, have not been recorded in public databases to the best of our knowledge. …”
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Sarcopenic obesity is attenuated by E-syt1 inhibition via improving skeletal muscle mitochondrial function
Published 2025-02-01“…Mechanistically, E-syt1 overexpression leads to mitochondrial calcium overload and mitochondrial ROS burst, inhibits the fusion of mitophagosomes with lysosomes, and impedes the acidification of lysosomes. …”
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