Adulthood consequences of spinal deformity surgeries in neurofibromatosis type 1 patients by Arihiko Tsukamoto, Koki Uno, Teppei Suzuki, Masaaki Ito, Keita Nakashima, Kenichiro Kakutani, Yoshiki Takeoka

“…Anterior and posterior fusion were performed in 18 patients, posterior fixation was performed in 20 patients. …”
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The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum by Alexander A. Morano, Wei Xu, Francesca M. Navarro, Neeta Shadija, Jeffrey D. Dvorin, Hangjun Ke

“…ABSTRACT Dynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events. Plasmodium falciparum encodes three dynamin-like proteins whose functions are poorly understood. …”
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Development of highly bioactive long-acting recombinant porcine FSH for batch production management of sows by Jiawei Zhang, Lei Shi, Xiaorong Zhong, Yunhe Bai, Jun Dou, Lu Zhang, Xiaochao Shi, Bingchun Wu, Zemin Tan, Lin Yan, Jinku Yu, Jingru Zhang, Guo Han, Jiansheng Xiong, Hua Zhang, Xingyuan Cao, Haoshu Luo

“…In the current study, we developed a novel long-acting recombinant porcine FSH (rpFSH-pFc) consisting of porcine FSH and porcine fragment crystallizable (Fc) via (G4S)3 linker by using the available protein fusion technology to control the follicular development and maturation. …”
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Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration by Junyi Zhu, Yijia Zhang, Yinuo Sun, Fangzheng Yu, Yang Lu, Qianqian Hu, Jiali Guo, Haijuan Zhang, Tianling Chen, Feifei Lian, Jian Wang, Xiaokun Li, Jian Xiao

“…By combining it with the corresponding scaffold carrier, the fusion of nanomaterials and biotherapy can be achieved, thereby providing a potential avenue for clinical treatment. …”
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Additively manufactured biodegradable Zn metamaterials with tunable Poisson’s ratio and enhanced mechanical properties by Yixuan Shi, Jiaqi Gao, Xuan Li, Zui Tao, Chengcong Huang, Shangyan Zhao, Yuzhi Wu, Youwen Yang, Yabin Yang, Yageng Li, Lu-Ning Wang

“…Using laser powder bed fusion (LPBF), we fabricated these Zn metamaterials and assessed their mechanical properties through simulations and compression tests. …”
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Ribosomal Protein L40e Fused With a Ubiquitin Moiety Is Essential for the Vegetative Growth, Morphological Homeostasis, Cell Cycle Progression, and Pathogenicity of Cryptococcus ne... by Jingyu Zhao, Jingyu Zhao, Yali Yang, Yali Yang, Yibin Fan, Jiu Yi, Chao Zhang, Zhongkai Gu, Weihua Pan, Julin Gu, Wanqing Liao, Wei Fang

“…Herein, we first report the contribution of the ubiquitin fusion protein Ubi1 (a ubiquitin monomer fused with the ribosome protein L40e, Rpl40e) in the growth and pathogenicity of Cryptococcus neoformans. …”
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Caracterización clínica bucodental y sociodemográfica de una comunidad vulnerable by Cerdán Puma S L, Contreras Dacduk L S, Fajardo J, Lattarulo Conti E S, Osorio Angulo L, Rissola C, Ausbruch C, Sánchez L M

“…Se originó a partir de la fusión de las villas 1, 11 y 14 en 1930.Sus habitantes provenían del interior de la Argentina y de países limítrofes. …”
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Clinical and cost-effectiveness of a guided internet-based Acceptance and Commitment Therapy to improve chronic pain–related disability in green professions (PACT-A): study protoco... by Claudia Buntrock, Harald Baumeister, Yannik Terhorst, Lina Braun, Ingrid Titzler, Johanna Freund, Janika Thielecke, David Ebert

“…Psychological flexibility (Chronic Pain Acceptance Questionnaire, Committed Action Questionnaire, Cognitive Fusion Questionnaire) will be evaluated as a potential mediator of the treatment effect. …”
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Plant-Based Antigen Production Strategy for SARS-CoV-2 Nucleoprotein and RBD and Its Application for Detection of Antibody Responses in COVID-19 Patients by Katerina Takova, Valeria Tonova, Ivan Minkov, Eugenia S. Mardanova, Nikolai V. Ravin, Stanislav Kotsev, Maria Pishmisheva, Gergana Zahmanova

“…Our study confirms that N and fusion HEV/RBD proteins, which are transiently expressed in plants, can be used to detect responses to SARS-CoV-2 in human sera reliably. …”
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Application of Machine Learning to Background Rejection in Very-high-energy Gamma-Ray Observation by Jie Li, Hongkui Lv, Yang Liu, Jiajun Huang, Yu Wang, Wenbin Lin

“…Among these methods, XGBoost, CatBoost, and DNN demonstrate stronger classification capabilities than decision trees and random forests, while the fusion model exhibits the best discriminatory ability. …”
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Bisphenol A induces apoptosis and disrupts testosterone synthesis in TM3 cells via reactive oxygen species-mediated mitochondrial pathway and autophagic flux inhibition by Wenzhe Yang, Feilong Pan, Tong Zhao, Fangfang Chen, Wenqi Shao, Jinhao Wang, Shirui Wang, Zichen Zhao, Kexiang Liu, Shuchen Zhao, Lijia Zhao

“…In addition, excessive ROS levels impaired autophagic degradation by inhibiting the fusion of autophagosomes with lysosomes. These abnormalities eventually induced apoptosis and inhibited testosterone synthesis in TM3 cells. …”
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Intratumoral and peritumoral radiomics using multi-phase contrast-enhanced CT for diagnosis of renal oncocytoma and chromophobe renal cell carcinoma: a multicenter retrospective st... by Yongsong Ye, Bei Weng, Yan Guo, Lesheng Huang, Shanghuang Xie, Guimian Zhong, Wenhui Feng, Wenxiang Lin, Zhixuan Song, Huanjun Wang, Tianzhu Liu

“…CMP models (AUC: 0.811–0.900) generally outperformed NP and fusion models (AUC: 0.728–0.756). SVM models (sensitivity: 62.50–88.89%; specificity: 63.16–77.78%; accuracy: 62.96–81.48%) outperformed manual diagnosis (sensitivity: 46.74–70.59%; specificity: 41.67–46.34%; accuracy: 52.27–59.78%). …”
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Spatial mapping of the localized corrosion behavior of a magnesium alloy AZ31B tungsten inert gas weld by Leslie G. (Bland) Miller, Corey M. Efaw, Rebecca F. Schaller, Kari Higginbotham, Steve D. Johns, Paul H. Davis, Elton Graugnard, John R. Scully, Michael F. Hurley

“…The formation of an Al-Zn solidification network in the fusion zone (FZ) at and near the TIG weld epicenter differs from the outer heat-affected zone (HAZ), where intermetallic particles (IMPs) are the notable secondary phase from the magnesium matrix. …”
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UAV Hyperspectral Remote Sensing Image Classification: A Systematic Review by Zhen Zhang, Lehao Huang, Qingwang Wang, Linhuan Jiang, Yemao Qi, Shunyuan Wang, Tao Shen, Bo-Hui Tang, Yanfeng Gu

“…Furthermore, this article delves into cutting-edge research trends, such as lightweight model development, hyperspectral large models, multisource data fusion, and model interpretability, while also highlighting future trends for UAV hyperspectral remote sensing classification technology, particularly in real-time monitoring and intelligent applications.…”
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ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1 by Živa Frangež, Deborah Gérard, Zhaoyue He, Marios Gavriil, Yuniel Fernández-Marrero, Yuniel Fernández-Marrero, S. Morteza Seyed Jafari, Robert E. Hunger, Philippe Lucarelli, Shida Yousefi, Thomas Sauter, Lasse Sinkkonen, Hans-Uwe Simon, Hans-Uwe Simon, Hans-Uwe Simon, Hans-Uwe Simon

“…Autophagy is a highly conserved cellular process in which intracellular proteins and organelles are sequestered and degraded after the fusion of double-membrane vesicles known as autophagosomes with lysosomes. …”
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First-principles calculations for the effect of irradiation-induced point defects on the hydrogen dissolution and diffusion in γ-Al2O3 by Xin-Dong Pan, Xiao-Chun Li, Jing Wang, Rongmei Yu, Chunying Pu, Hai-Shan Zhou, Guang-Nan Luo

“…FeAl/Al2O3 is considered the most promising candidate material for tritium permeation barrier (TPB) due to numerous advantages. γ-Al2O3 phase structure is commonly found in FeAl/Al2O3, and is crucial to its effectiveness. In fusion reactors, high-energy neutrons generate a large number of irradiation-induced defects, significantly affecting the performance of γ-Al2O3. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…By treating pregnant mice with TCDD (40 μg/kg) at the vital craniofacial patterning stages (embryonic day 8.5, 10.5 and 12.5), and scanning and reconstructing the skulls at embryonic day 18.5 using microCT, we found that TCDD exposure at the earlier and later patterning stages induced variable craniofacial malformations, including premature fusion of metopic and coronal sutures, truncated palatal processes of maxillary and palatine bones, as well as opening oriented pterygoid processes. …”
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Nuclear talin-1 provides a bridge between cell adhesion and gene expression by Alejandro J. Da Silva, Hendrik S.E. Hästbacka, Mikael C. Puustinen, Jenny C. Pessa, Jens C. Luoto, Erika Sundström, Benjamin T. Goult, Guillaume Jacquemet, Eva Henriksson, Lea Sistonen

“…To determine the functional impact of nuclear TLN1, we expressed a TLN1 fusion protein containing a nuclear localization signal. …”
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MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder by Yan Chen, Yun Liu, Ming Xiao, Chun Wang, Panpan Hu, Qiuchen Cao, Hu Feng, Jingfan Xu, Weixi Feng, Huaiqing Sun, Huachen Ding, Junying Gao

“…Eight-week-old male C57BL/6 mice had miR-451a overexpression in the medial prefrontal cortex (mPFC) via adeno-associated virus serotype 9 vectors encoding a pri-mmu-miR-451a-GFP fusion protein followed by behavioural and pathological analyses. …”
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Savolitinib Induced Pathological Complete Response in Non-small Cell Lung Cancer with MET Amplification: A Case Report by Meng LU, Ran ZHANG, Baiwei LI, Haidi XU, Yongkuan GUO, Jian YOU, Bingsheng SUN

“…For locally advanced NSCLC patients with positive driver gene mutations such as EGFR, anaplastic lymphoma kinase (ALK) fusion and METex14m, there have been relevant cases reported that neoadjuvant targeted therapy could achieve a good prognosis, but there have been no cases of neoadjuvant targeted therapy for locally advanced NSCLC patients with METamp. …”
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