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Clinical findings of acute necrotizing esophagitis complicated by diabetic ketoacidosis
Published 2024-05-01Get full text
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Enhanced Intrusion Detection in Drone Networks: A Cross-Layer Convolutional Attention Approach for Drone-to-Drone and Drone-to-Base Station Communications
Published 2025-01-01“…CLCAN accurately detects complex cyber threats using multi-scale convolutional processing, hierarchical contextual attention, and dynamic feature fusion. Preprocessing methods like weighted differential scaling and gradient-based adaptive resampling improve data quality and reduce class imbalances. …”
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Self-assembled Human Serum Protein-based Core-shell Nanoparticles to inhibit key oncogenic signalling in Drug-Resistant Leukemia
Published 2024-10-01“…Molecular analysis of approximately 14 refractory CML patients identified resistance to the standard treatment drug, imatinib, attributed to the overex-pression of the STAT5-transferrin pathway alongside the classic BCR-ABL fusion gene. To address this, we developed two dual-drug-loaded core-shell nanoparticles: (a) CS-NP1: Protamine sulfate nanocores carrying BCR-ABL siRNA and an albumin shell loaded with the STAT5 in-hibitor sorafenib, denoted as (PS-siRNA)-(Tf-Soraf) CS-NP; (b) CS-NP2: features a second-generation BCR-ABL inhibitor, dasatinib, in the albumin nanocore, and sorafenib in the transferrin nanoshell, labeled as (nAlb-Dasa)-(Tf-Soraf). …”
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Development of an Enzyme-Linked Immunosorbent Assay Based on a Monoclonal Antibody for the Rapid Detection of Citrinin in Wine
Published 2024-12-01“…A hybridoma cell line (3G5) that secretes anti-CIT monoclonal antibodies (mAbs) was screened via CIT-H-BSA immunisation of mice, cell fusion, and ELISA screening technology. The cell line was injected intraperitoneally to prepare ascites. …”
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Calponin 3 Regulates Myoblast Proliferation and Differentiation Through Actin Cytoskeleton Remodeling and YAP1-Mediated Signaling in Myoblasts
Published 2025-01-01“…Furthermore, CNN3 knockdown impaired myogenic differentiation, as evidenced by reduced levels of MyoD, MyoG, and MyHC, key markers of myogenic commitment and maturation, and immunocytochemistry showed that myotube formation was diminished in CNN3-suppressed cells, which was supported by lower differentiation and fusion indices. These findings reveal that CNN3 is essential for myogenic differentiation, playing a key role in regulating actin remodeling and cellular localization of YAP1 to orchestrate the proliferation and differentiation in myogenic progenitor cells. …”
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De novo biosynthesis of quercetin in Yarrowia Lipolytica through systematic metabolic engineering for enhanced yield
Published 2025-01-01“…We designed a kaempferol biosynthetic pathway by integrating multiple-copy fusion enzyme expression modules, F3H-(GGGGS)2-FLS, into the genome with an optimized linker (GGGGS)2 to enhance kaempferol production from naringenin. …”
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Logical reasoning for human activity recognition based on multisource data from wearable device
Published 2025-01-01“…In order to realize the natural fusion of signal processing and logical reasoning in behavior recognition research, this work designs a lightweight behavior recognition solution using the pertinent theories of ontology reasoning in classical artificial intelligence. …”
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The Inhibitory Effect of Alisol A 24-Acetate from Alisma canaliculatum on Osteoclastogenesis
Published 2015-01-01“…Furthermore, it inhibited the expression of DC-STAMP and cathepsin K, which are related to cell-cell fusion of osteoclasts and bone resorption, respectively. …”
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Implicit link prediction based on extended social graph
Published 2024-12-01“…The algorithm completes user attribute information through a multi-task fusion attribute inference framework built on associative learning. …”
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Decentralized and Asymmetric Multi-Agent Learning in Construction Sites
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Research on integrated 3D geological modeling of vector grid ——taking the core area of Tianfu New Area as an example
Published 2025-12-01“…Existing urban integration is a fusion and integration of 3D models of different spatial locations, but there is little research on the integration of different expression models in the same spatial location, especially in the integration of 3D geological structure model and 3D geological attribute model. …”
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Long-term reconstructed vegetation index dataset in China from fused MODIS and Landsat data
Published 2025-01-01“…This study revised a machine learning spatiotemporal fusion model (InENVI) to produce a high-resolution NDVI dataset with 8-day temporal and 30 m spatial resolution, covering China from 2001 to 2020. …”
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Combination of an E-Nose and an E-Tongue for Adulteration Detection of Minced Mutton Mixed with Pork
Published 2019-01-01“…Good correlations were found between the signals obtained from E-tongue, E-nose, and fusion data of E-nose and E-tongue and proportions of pork in minced mutton with correlation coefficients higher than 0.90 in the calibration and validation data sets. …”
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Identification of fine antigenic epitopes of Tamdy virus glycoprotein Gn fragment and establishment of ELISA detection method
Published 2025-01-01“…Conclusions Eight precise epitopes were identified, and an indirect ELISA method based on fusion multiepitope peptide (r-Gn-MEPX2) was developed and implemented, featuring high sensitivity, accuracy, and specificity. …”
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