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741
Establishment and Characterization of a Human Small Cell Osteosarcoma Cancer Stem Cell Line: A New Possible In Vitro Model for Discovering Small Cell Osteosarcoma Biology
Published 2016-01-01“…We have proved their in vitro mesenchymal and embryonic stem phenotype. Additionally, we have showed their neoplastic phenotype, since the original tumor bulk is a high grade osteosarcoma. …”
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742
The Critical Role of YAP/BMP/ID1 Axis on Simulated Microgravity‐Induced Neural Tube Defects in Human Brain Organoids
Published 2025-02-01“…Abstract Integrated biochemical and biophysical signals regulate embryonic development. Correct neural tube formation is critical for the development of central nervous system. …”
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743
Older adults’ reasons for applying to a nursing home – a document analysis
Published 2024-12-01“…Background Ageing in place is the social norm in Sweden, yet older adults apply for a nursing home on a daily basis which suggests that ageing in place needs further study as it is not suitable for everyone. Aim: to study descriptions of older adults’ reasons for applying to a nursing home in documents of granted nursing home decisions.Materials and methods One hundred and sixty decisions were analyzed through document analysis with a deductive content analysis using the Canadian Model of Occupational Performance-Engagement (CMOP-E) as a framework.Results Reasons for applying were represented in the three factors of the CMOP-E. …”
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744
Genes related to neural tube defects and glioblastoma
Published 2025-01-01“…Abstract There are many similarities between early embryonic development and tumorigenesis. The occurrence of neural tube defects (NTDs) and glioblastoma (GBM) are both related to the abnormal development of neuroectodermal cells. …”
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745
Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
Published 2015-01-01“…By breaking the continuity of bone tissue, a spread-over-time and complex bone healing process is initiated, considered a recapitulation of embryonic intracartilaginous ossification. This process is a cascade of local and systemic phenomena spread over time, involving whole cell lineages and various cytokines and growth factors. …”
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746
Application of PEI-Modified Magnetic Nanoparticles as Gene Transfer Vector for the Genetic Modification of Animals
Published 2012-01-01“…To evaluate the performance of the magnetic nanoparticles as gene transfer vector for breeding transgenic animals, we investigated a new approach to deliver green fluorescent protein (GFP) gene to porcine kidney 15 (PK-15) and porcine embryonic fibroblast (PEF) cells using PEI-modified magnetic nanoparticles as gene vector. …”
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747
Neurally Derived Tissues in Xenopus laevis Embryos Exhibit a Consistent Bioelectrical Left-Right Asymmetry
Published 2012-01-01“…Consistent left-right asymmetry in organ morphogenesis is a fascinating aspect of bilaterian development. Although embryonic patterning of asymmetric viscera, heart, and brain is beginning to be understood, less is known about possible subtle asymmetries present in anatomically identical paired structures. …”
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748
Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133?
Published 2025-01-01“…Prominin-1+ EVs also mediate intercellular communication during embryonic development and adult homeostasis in healthy individuals, while disseminating biological information during diseases. …”
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749
Novel Action of FSH on Stem Cells in Adult Mammalian Ovary Induces Postnatal Oogenesis and Primordial Follicle Assembly
Published 2016-01-01“…Stem cells comprise two distinct populations including spherical, very small embryonic-like stem cells (VSELs which express nuclear OCT-4 and other pluripotent and primordial germ cells specific markers) and slightly bigger ovarian germ stem cells (OGSCs with cytoplasmic OCT-4 which are equivalent to spermatogonial stem cells in the testes). …”
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750
Dental Mesenchymal Stem/Stromal Cells and Their Exosomes
Published 2018-01-01“…Stem cells derived from human dental pulp tissue (DP-MSC) differ from the other mesenchymal stem cells prepared from bone marrow or adipose tissue due to their embryonic origin from the neural crest and are of special interest because of their neurotropic character. …”
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751
Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease
Published 2025-01-01“…In this study, we utilized preclinical in vitro models—immortalized cell lines and hepatocyte-like cells derived from human embryonic stem cells—exposed to clinically relevant steatotic-inducing agents. …”
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752
Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
Published 2012-01-01“…Exogenous expression of Oct4, Sox2, Klf4, and cMyc forces mammalian somatic cells to adopt molecular and phenotypic characteristics of embryonic stem cells, commencing with the required suppression of lineage-associated genes (e.g., Thy1 in mouse). …”
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753
A Systematic Review of Parental Occupational Pesticide Exposure and Geographical Proximity to Agricultural Fields in Association with Neural Tube Defects
Published 2025-01-01“…The inclusion criteria were epidemiological studies involving pesticides exposure during embryonic development, written in English, Portuguese, or Spanish, and performed in 12 databases. …”
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754
Magnetic Targeted Delivery of Induced Pluripotent Stem Cells Promotes Articular Cartilage Repair
Published 2017-01-01“…The samples were graded according to the histologic grading score for cartilage regeneration. m-iPS cells differentiated into three embryonic germ layers and formed teratomas in the subcutaneous tissue. …”
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755
Conflits, féminité et identités diasporiques. Le pouvoir de la représentation chez Pratibha Parmar et Gurinder Chadha
Published 2010-09-01“…Gurinder Chadha abandoned the documentary format as early as 1993. Meant to make everyone laugh, Bhaji on the Beach, her first mainstream comedy, produced a reconciled, all-inclusive portrait of Britain, as did Bend It Like Beckham (2002) and Bride and Prejudice (2004) years later. …”
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756
« There are kisses for all » : Le defilé des jeunes hommes
Published 2006-12-01“…However, the film director chose to claim his film adaptation as the most faithful rendition on screen of the famous gothic novel. Everyone knows fidelity is not the most appropriate word when one deals with this film, owing to the essential addition made by the screenwriter James V. …”
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757
The effect of culture media and seeding densities on the human malignant testicular germ cell line (NT2/D1) growth pattern
Published 2025-02-01“…The NT2/D1 cell line, a pluripotent embryonal carcinoma, is valuable in cancer and developmental biology research due to its differentiation potential into neurons and glial cells. …”
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758
COMPARATIVE ASSESSMENT OF RATIONAL ANTIBIOTIC USAGE AMONG NON-PHYSICIAN HEALTH PROFESSIONALS AND LAY INDIVIDUALS
Published 2024-05-01“…Considering that demographic characteristics do not have a significant impact on attitudes towards antibiotic use, educational efforts in this area should be accessible and effective for everyone.…”
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759
Dynamic regimes in planetary cores: $\tau $–$\ell $ diagrams
Published 2024-05-01“…A complete toolbox is provided, allowing everyone to construct a $\tau $–$\ell $ diagram of a numerical simulation, a laboratory experiment, a theory, or a natural object.…”
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760
What’s in a Name? On Language, Concept Formation, and the Definition Disputes in the Entrepreneurship Literature
Published 2014-06-01“…When it comes to entrepreneurship, the conceptual framework of economics is disjointed: On the one hand almost everyone agrees that entrepreneurial initiative and creativity are critical for economic progress. …”
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