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5461
Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head necrosis
Published 2025-01-01“…In vitro, SBD inhibited osteoblast apoptosis, promoted PI3K/Akt and VEGF pathway expression, and enhanced osteoblast differentiation and mineralization.ConclusionThis study integrates network pharmacology with experimental validation, showing that SBD protects against SONFH by inhibiting osteoblast apoptosis via PI3K/Akt and VEGFR pathways. …”
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5462
Targeting the NOTCH2/ADAM10/TCF7L2 Axis‐Mediated Transcriptional Regulation of Wnt Pathway Suppresses Tumor Growth and Enhances Chemosensitivity in Colorectal Cancer
Published 2025-01-01“…Furthermore, use of adavivint or blockage of ADAM10/NOTCH2/TCF7L2 signaling enhances the chemosensitivity of CRC cells. Overall, this study provides a promising candidate for the development of small‐molecule inhibitors and reveals a potential therapeutic target for CRC.…”
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5463
‘Photodynamic therapy light’: An enhanced treatment protocol for actinic keratoses with minimal pain and optimal clinical outcome by combining laser-assisted low irradiance PDT with shortened daylight PDT
Published 2025-02-01“…Results: Between March and November 2019, we successfully treated 152 cases using the enhanced ‘PDT light’ procedure, with 137 cases achieving at follow-up 1 (on average after 8.14 months) good-to-excellent clearance rates (CLA and CLB together 90 %) and minimal adverse effects. …”
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5465
Enhancement of Cognitive Benefits and Anti-Anxiety Effects of <i>Phytolacca americana</i> Fruits in a Zebrafish (<i>Danio rerio</i>) Model of Scopolamine-Induced Memory Impairment
Published 2025-01-01“…Our findings suggest that both PEC and PEU possess anxiolytic effects, alleviating SCO-induced anxiety and enhancing cognitive performance in amnesic zebrafish. …”
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5466
Multi-Scale Analysis of Urban Greenspace Exposure and Equality: Insights from a Population-Enhanced Vegetation Index (EVI)-Weighted Model in the West Side Straits Urban Agglomeration
Published 2025-01-01“…Urban greenspaces (UGSs) are pivotal for ecological enhancement and the well-being of urban residents. The accurate quantification of greenspace exposure (GE) and its distributional equality is essential for equitable urban planning and mitigating inequalities in greenspace access. …”
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5467
Enhanced renoprotective effects of combined glucagon‐like peptide‐1 receptor agonists and sodium‐glucose cotransporter 2 inhibitors in type 2 diabetes mellitus: Real‐world evidence
Published 2025-02-01“…Conclusions Dual therapy with GLP‐1 RA and SGLT2i is supported to enhance renal outcomes and address the growing burden of diabetic kidney disease.…”
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Enhanced formula-based method to estimate burnup, initial enrichment, and cooling time using limited gamma-ray source data of reference PWR spent nuclear fuel assemblies
Published 2025-02-01“…The estimation model proposed in this study enhanced IE estimations, maintaining the reliability of BU and CT estimations. …”
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Foliar application of 24-epibrassinolide enhances leaf nicotine content under low temperature conditions during the mature stage of flue-cured tobacco by regulating cold stress tolerance
Published 2025-01-01“…Abstract Background Low temperatures disrupt nitrogen metabolism in tobacco, resulting in lower nicotine content in the leaves. 24-epibrassinolide (EBR) is a widely used plant growth regulator known for its roles in enhancing cold tolerance and nitrogen metabolism. Nevertheless, it remains unclear whether EBR enhances leaf nicotine content under low temperature conditions during the mature stage of flue-cured tobacco. …”
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Men care too: a qualitative study examining women’s perceptions of fathers’ engagement in early childhood development (ECD) during an ECD program for HIV-positive mothers in Malawi
Published 2022-07-01“…Interviews assessed mothers’ perceptions of father buy-in and engagement in the programme and ECD activities. Data were coded using inductive and deductive strategies and analysed using constant comparison methods in Atlas.ti V.1.6.Setting Four health facilities in Malawi where PMTCT services were provided.Participants Study participants were mothers infected with HIV who were enrolled in the PMTCT–ECD programme for >6 months.Interventions The PMTCT–ECD intervention provided ECD education and counselling sessions during routine PMTCT visits for mothers infected with HIV and their infants (infant age 1.5–24 months). …”
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Human Umbilical Cord Mesenchymal Stem Cells Encapsulated with Pluronic F-127 Enhance the Regeneration and Angiogenesis of Thin Endometrium in Rat via Local IL-1β Stimulation
Published 2022-01-01“…Embedding of hUC-MSCs with PF-127 could prolong the hUC-MSCs retaining, which could further enhance endometrium thickness and gland number in the thin endometrium rat model via increasing angiogenesis capacity. …”
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5480
Enhanced Power Conversion Efficiency of P3HT : PC71BM Bulk Heterojunction Polymer Solar Cells by Doping a High-Mobility Small Organic Molecule
Published 2015-01-01“…The device with 0.6 wt% TIPS-pentacene exhibited the enhanced short-circuit current and fill factor by 1.23 mA/cm2 and 7.8%, respectively, resulting in a maximum power conversion efficiency of 4.13%, which is one-third higher than that of the undoped one. …”
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