The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design by Wei‐Wei Wang, Su‐Yu Ji, Ping Xu, Yan Zhang, Yan Zhang

Get full text

Coplanar Waveguide-Fed Broadband Microwave Devices with (or without) a Thin Dielectric Substrate for Use in Flexible Electronic Systems by Rafal Lech, Wojciech Marynowski, Adam Kusiek, Jerzy Mazur

“…Two examples of microwave devices, fed by a coplanar waveguide and realized on a thin substrate (or without such a substrate), are employed to investigate the influence of devices’ curvatures and the proximity of different materials on their parameters. …”
Get full text

Advancements in functional tetrahedral DNA nanostructures for multi-biomarker biosensing: Applications in disease diagnosis, food safety, and environmental monitoring by Yun Qiu, Yixing Qiu, Wenchao Zhou, Dai Lu, Huizhen Wang, Bin Li, Bin Liu, Wei Wang

“…This review highlights recent advancements in functional tetrahedral DNA nanostructures (FTDN) for various biomarkers monitoring, including nucleic acid, protein, mycotoxin, agent, and metal ion. …”
Get full text

Integrating Explainable Artificial Intelligence With Advanced Deep Learning Model for Crowd Density Estimation in Real-World Surveillance Systems by Sultan Refa Alotaibi, Hanan Abdullah Mengash, Mohammed Maray, Faiz Abdullah Alotaibi, Abdulwhab Alkharashi, Ahmad A. Alzahrani, Moneerah Alotaibi, Mrim M. Alnfiai

“…Crowd Density Detection in Smart Video Surveillance involves advanced computer vision (CV) techniques to improve the efficiency and accuracy of crowd monitoring. …”
Get full text

Treatment Patterns and Outcomes Among Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States by Robert L. Coleman, Jamie Garside, Jean Hurteau, Joehl Nguyen, Monica Kobayashi

“…**Background:** Patients with advanced or recurrent endometrial cancer (EC) typically have limited treatment options and poor long-term survival outcomes following first-line therapy. …”
Get full text

Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review by Chun-Qiao Chen, Hui Huang, Min Pan, Zhe Jia, Jing Zhang, Qiu-Qiu Chen

“…Abstract Background Nasopharyngeal cancer (NPC) is a common head and neck malignant tumor, which is difficult to treat at the advanced NPC due to its occult and high metastatic potential to the cervical lymph nodes and distant organs. …”
Get full text

Advanced Technologies from and Through a Prototype Radio Lesson with Budding Journalists: The Views and Attitudes of Xers, Millennials, and Zoomers by Constantinos Nicolaou

Subjects: Get full text

Prognostic and Predictive Value of CpG Island Methylator Phenotype in Patients with Locally Advanced Nonmetastatic Sporadic Colorectal Cancer by Yuwei Wang, Yadong Long, Ye Xu, Zuqing Guan, Peng Lian, Junjie Peng, Sanjun Cai, Guoxiang Cai

“…Patients with CIMP positive locally advanced sporadic colorectal cancers may not benefit from 5-fluorouracil based adjuvant chemotherapy.…”
Get full text

Gaëlle Aggéri, Inventer les villes-natures de demain... Gestion différenciée, gestion durable des espaces verts by Audrey Marco

Get full text

New Method for Determination of Drain Saturation Voltage in Short Channel MOS Devices Between Liquid Helium to Room Temperature by Y. Amhouche, A. El Abbassi, K. Raïs, E. Bendada, R. Rmaily

“…The method has been tested using main of channel length MOSFET devices and compared with others methods.…”
Get full text

A case study in statistical software development for advanced evidence synthesis: the combined value of analysts and research software engineers by Naomi Bradbury, Tom Morris, Clareece Nevill, Janion Nevill, Ryan Field, Suzanne Freeman, Nicola Cooper, Alex Sutton

Get full text

Assessing the effectiveness of the SOLIO Alfa Cure Plus device in treating low back pain: a randomized controlled study by Hadari Yotam, Pesah Galia, Goor-Aryeh Itay, Ungar Lior

Subjects: Get full text

Overexpression of Delayed Rectifier K+ Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure by Itsuro Kazama, Yoshio Maruyama, Yasuhiro Endo, Hiroaki Toyama, Yutaka Ejima, Mitsunobu Matsubara, Shin Kurosawa

“…In the cortical interstitium of advanced CRF rat kidneys, leukocytes proliferated in situ and overexpressed Kv1.3 channel protein in their cytoplasm. …”
Get full text

Advanced microgrid optimization using price-elastic demand response and greedy rat swarm optimization for economic and environmental efficiency by Arvind R. Singh, Bishwajit Dey, Mohit Bajaj, Sahil Kadiwala, Rangu Seshu Kumar, Soham Dutta, Ievgen Zaitsev

“…Abstract In this paper, a comprehensive energy management framework for microgrids that incorporates price-based demand response programs (DRPs) and leverages an advanced optimization method—Greedy Rat Swarm Optimizer (GRSO) is proposed. …”
Get full text

A phase I study of the CDK4/6 inhibitor ribociclib combined with gemcitabine in patients with advanced solid tumors by Aurora Norman, Mahesh Seetharam, Jacob Allred, Jianping Kong, Mateusz Opyrchal, Wen Wee Ma, Yanyan Lou, Grace K. Dy, Amit Mahipal, S. John Weroha, Andrea E. Wahner Hendrickson, Joel M. Reid, Alex A. Adjei

“…Methods In this single arm multicohort phase I trial, we evaluated the safety and efficacy of ribociclib plus gemcitabine in patients with advanced solid tumors. Patients received gemcitabine intravenously on days 1 and 8 followed by ribociclib days 8–14, with treatment repeated every 3 weeks. …”
Get full text

Design of Stunting Prevention Education Media Package Based on Technology and Local Wisdom by Lia Nurcahyani, Dyah Widiyastuti, Wiwit Estuti, Arief Tarmansyah Iman, Yeni Fitrianingsih, Fahmi Hafid

Subjects: Get full text

Penser éducation au politique et questions environnementales dans la démocratie by Camille Roelens

Subjects: “…Political philosophy of education…”
Get full text

The professional readiness of student-teachers in physical education in Ukraine's war-torn areas by Igor Vypasniak, Lyudmila Shesterova, Iryna Kryventsova

Subjects: Get full text

USAGE OF ARTIFICIAL INTELLIGENCE IN THE PAKISTANI MEDICAL EDUCATION SYSTEM; IS IT REALLY IMPLEMENTABLE AND BENEFICIAL? by Saima Askari

Get full text