Whole genomic analysis uncovers high genetic diversity of rifampicin-resistant Mycobacterium tuberculosis strains in Botswana by Tuelo Mogashoa, Tuelo Mogashoa, Johannes Loubser, Ontlametse T. Choga, Ontlametse T. Choga, Justice Tresor Ngom, Wonderful T. Choga, Wonderful T. Choga, Mpaphi B. Mbulawa, Tuduetso Molefi, One Stephen, Topo Makhondo, Kedumetse Seru, Patience Motshosi, Boitumelo Zuze, Joseph Makhema, Rosemary M. Musonda, Dimpho Otukile, Chawangwa Modongo, Botshelo T. Kgwaadira, Keabetswe Fane, Simani Gaseitsiwe, Rob M. Warren, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Sikhulile Moyo, Anzaan Dippenaar, Elizabeth M. Streicher

“…The most frequently observed drug resistance mutations for rifampicin, isoniazid, ethambutol, streptomycin, pyrazinamide, and fluoroquinolones were rpoB S450L (28.6%), katG S315T (60.5%), embA_c.-29_-28delCT, embB Q497R (31.7%), rrs_n.517C>T (47.1%), pncA_c.375_389delCGATGAGGTCGATGT (36.0%) and gyrA A90V (79.4%), respectively. …”
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Wetland degradation monitoring using multi-temporal remote sensing data and watershed land degradation index by I. Ridwan, S. Kadir, N. Nurlina

“…As a consequence of this, some land degradation management measures ought to be created in advance, guaranteeing the protection of this vital region, which is a source of freshwater. …”
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Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma by Metoboroghene O. Mowoe, Metoboroghene O. Mowoe, Hisham Allam, Joshua Nqada, Marc Bernon, Karan Gandhi, Sean Burmeister, Urda Kotze, Miriam Kahn, Christo Kloppers, Suba Dharshanan, Zafirah Azween, Pamela Maimela, Paul Townsend, Eduard Jonas, Jonathan M. Blackburn, Jonathan M. Blackburn

“…Autoantibodies (AAbs) in principle make attractive biomarkers as they arise early in disease, report on disease-associated perturbations in cellular proteomes, and are static in response to other common stimuli, yet are measurable in the periphery, potentially well in advance of the onset of clinical symptoms.MethodsHere, we used high-throughput, custom cancer antigen microarrays to identify a clinically relevant autoantibody biomarker combination able to differentially detect PDAC. …”
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Transcutaneous vagus nerve stimulation as a pain modulator in knee osteoarthritis: a randomized controlled clinical trial by Gehad Gamal Elsehrawy, Maha Emad Ibrahim, Nermeen Hassan A.moneim, Mohamed Ahmed Hefny, Nashwa Kamel El Shaarawy

“…Methods In this 12-week study, we stimulated the auricular branch of the vagus nerve with an auricular electrode connected to a transcutaneous electrical nerve stimulation device once a day for 3 days each week for 12 weeks. …”
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Novel Pythagorean fuzzy score function to optimize fuzzy transportation models by Ritu, Tarun Kumar, Jahnvi, Kapil Kumar, Nitesh Dhiman, M.K. Sharma

“…This paper utilizes an advanced extension of fuzzy sets, known as Interval-Valued Pythagorean Fuzzy Sets (IVPFS) in transportation models. …”
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Determinants of Pelvic Floor Disorders among Women Visiting the Gynecology Outpatient Department in Wolkite University Specialized Center, Wolkite, Ethiopia by Ayana Benti Terefe, Tolesa Gemeda Gudeta, Girma Teferi Mengistu, Seboka Abebe Sori

“…In this study, age at first pregnancy, number of vaginal births, history of episiotomy, and menopause were independently associated with pelvic floor disorder. Therefore, educating women about the year of their first pregnancy, promoting family planning, and advice on the prevention of routine episiotomy by a health professional is recommended.…”
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Providing an Anti-Marketing Model to Prevent Criminal Behaviors in Online and Digital Businesses by Ghasem Zarei, Younes Nikkhah

“…Objective The development of the digital environment in most areas of business has led to an increase in deceptive practices and unconventional behaviors. With the advancement of the digital environment, unconventional channels have emerged, leading to various risks such as life, financial, and behavioral risks affecting individuals and businesses. …”
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Comprehensive assessment of a nationwide simulation-based course for artificial life support. by Mateusz Puslecki, Marek Dabrowski, Marcin Ligowski, Bishoy Zakhary, Ahmed S Said, Kollengode Ramanathan, Elaine Cooley, Lukasz Puslecki, Sebastian Stefaniak, Piotr Ziemak, Ilona Kiel-Puslecka, Agata Dabrowska, Tomasz Klosiewicz, Maciej Sip, Radoslaw Zalewski, Malgorzata Ladzinska, Wojciech Mrowczynski, Piotr Ladzinski, Lidia Szlanga, Konrad Baumgart, Piotr Kupidlowski, Lukasz Szarpak, Marek Jemielity, Bartlomiej Perek

“…The implementation of the education program during COVID-19 pandemic may be helpful in founding specialized Advanced Life Support centers and teams including mobile ones. …”
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Real-World Life Analysis of a Continuous Glucose Monitoring and Smart Insulin Pen System in Type 1 Diabetes: A Cohort Study by Paola Pantanetti, Giovanni Cangelosi, Sara Morales Palomares, Gaetano Ferrara, Federico Biondini, Stefano Mancin, Gabriele Caggianelli, Mauro Parozzi, Marco Sguanci, Fabio Petrelli

“…While Type 2 diabetes (T2D) is more prevalent, Type 1 diabetes (T1D) presents unique therapeutic challenges, particularly in younger individuals. Advances in diabetes management, such as continuous glucose monitoring (CGM), insulin pumps (IP), and, more recently, smart multiple dose injection (MDI) pens, have significantly enhanced glycemic control and improved patients’ quality of life. …”
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The Effect of Cognitive-Motor Dual Tasks on the Risk of Falls in Female Saudi Students: A Cross-Sectional Study by Alatawi SF, Mahmoud HM

“…ROF was measured using the Biodex balancing device for balance alone (no DT) and with DT (motor and two cognitive tasks). …”
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Pan-tumor analysis to investigate the obesity paradox in immune checkpoint blockade by Evan J Lipson, Ludmila Danilova, Elizabeth M Jaffee, Won Jin Ho, Mark Yarchoan, Yasser Ged, Jean Hoffman-Censits, Jennifer Durham, Sanjay Bansal, Chester Kao, Rajat Mohindra, Stephanie L Alden, Tanguy Y Seiwert, Soren Charmsaz, Howard L Li, Kabeer Munjal, Hua-Ling Tsai, Alexei Hernandez, Erin M Coyne, Rachel Garonce-Hediger, Laura Tang, Marina Baretti, Kathryn Howe, G Scott Chandler, Madelena Brancati, Aanika Warner, Ervin Griffin, Mari Nakazawa, Chris Thoburn, Jennifer Gizzi, Nicole E Gross, Elsa Hallab, Sarah S Shin, Aditi Guha

“…To interrogate mechanisms of divergent immune responses in obese and non-obese patients, we examined the relationship among obesity status, clinical responses, and immune profiles from a diverse, pan-tumor cohort of patients treated with ICI-based therapy.Methods From June 2021 to March 2023, we prospectively collected serial peripheral blood samples from patients with advanced or metastatic solid tumors who received ICI as standard of care at Johns Hopkins. …”
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Constitutional identity and national values in the conditions of permanent threats to Ukraine’s stateship by V. Kovalchuk

“…This is crucial both for uniting a multiethnic country into a single people (nation) and for advancing state-building processes. Constitutional identity and national identity should become foundational elements of the political and legal ideology of the modern Ukrainian constitutional state. …”
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Mısır Meselesinin Gölgesinde 1838 Ticaret Antlaşması by Mahmut Akpınar

“…Osmanlı iç karışıklıkların üstesinden gelemezken, valiliğe atadığı Mehmed Ali Paşa’nın verdiği mücadele ve Avrupa’da devam eden Koalisyon Savaşlarının yarattığı baskı nedeniyle İngilizler Mısır’da tutunamadı. …”
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Incidence of opportunistic infections and its predictors among HIV/AIDS patients on antiretroviral therapy in Gondar University Comprehensive and Specialized Hospital, Ethiopia by Mequanente Dagnaw, Haileab Fekadu, Adhanom Gebre Egziabher, Tesfaye Yesfue, Meera Indracanti, Alemu Tebeje

“…In terms of predictors, such as a low CD4 count and an advanced WHO stage (II or III), bedridden functional status was found to be significantly associated with OIs.…”
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The Interaction Mechanisms of Swimming Biomimetic Fish Aligned in Parallel Using the Immersed Boundary Method by Xiaowei Cai, Tonghua Xu, Jun Zhang, Yanmei Jiao, Haiyang Yu

“…Investigating the coupled mechanism of biomimetic fish exhibiting autonomous swimming capabilities advances our understanding of fish schooling phenomena and simultaneously aids in refining the structural and formation configurations of underwater robotic vehicles. …”
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High-performance CT features supporting accurate pre-operative tumor staging in colon cancer by Jianhua Yuan, Cangzheng Jin, Jianrong Si, Baobao Liu, Xiaohan Si, Jianzhi Chen

“…We aimed to pathologically interpret the key CT findings in order to identify reliable markers for pre-treatment staging of colon cancer.Patients and methodsThe following CT features from 136 colon adenocarcinomas were analyzed: colon wall pliability, outline contour, pericolic fat attenuations and vascularity, tumor fusion with adjacent organs, ascites, tumor size, and relevance between tumor and retroperitoneal fascia. …”
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StrideHD: A Binary Hyperdimensional Computing System Utilizing Window Striding for Image Classification by Dehua Liang, Jun Shiomi, Noriyuki Miura, Hiromitsu Awano

“…Hyper-Dimensional (HD) computing is a brain-inspired learning approach for efficient and fast learning on today’s embedded devices. HDC first encodes all data points to high-dimensional vectors called hypervectors and then efficiently performs the classification task using a well-defined set of operations. …”
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What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review by Benedict Hayhoe, Azeem Majeed, Geva Greenfield, Ana Luísa Neves, Henock B Taddese, Kalthum Patail, Hui Hsuan Pai

“…About 40% of the studies described unfavourable aspects related to uploading of excessive information, monitoring device incompatibility, episodic app crashes and telephone handling issues.Conclusion The review supports the favourable view of mobile applications as promising tools in helping patients with diabetes to self-manage. …”
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Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study by Nehad M. Ayoub, Rami J. Yaghan, Nour M. Abdo, Ismail I. Matalka, Laila M. Akhu-Zaheya, Alia H. Al-Mohtaseb

“…Obesity was associated with advanced stage and grade of breast carcinoma at diagnosis. …”
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Implementasi QR Code Berbasis Android pada Sistem Presensi by Afif Priyambodo, Ledya Novamizanti, Koredianto Usman

“…The hardware system consists of an Android device and a student card. The decoder system carries out the QR-Code detection process with the Smart Presence application. …”
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