Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. by Caroline C McGrouther, Aaditya V Rangan, Arianna Di Florio, Jeremy A Elman, Nicholas J Schork, John Kelsoe, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium

“…<h4>Results</h4>In this paper, we leverage recent advances in heterogeneity analysis to look for genetically-driven subgroups (i.e., biclusters) within the broad phenotype of Bipolar Disorder. …”
Get full text

Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration by Lingling E, Rongjian Lu, Jianwei Sun, Hongbo Li, Wen Xu, Helin Xing, Xing Wang, Tao Cheng, Shuo Zhang, Xiaocao Ma, Rong Zhang, Hongchen Liu

“…In the in vitro three-dimensional culture microenvironment, nHAC/PLA supported hUC-MSCs’ adhesion, proliferation, and differentiation; the microenvironment containing OMD or OMD and rhBMP-7 shortened cell proliferation progression and made osteogenic differentiation progression advance; rhBMP-7 significantly attenuated the inhibiting effect of OMD on hUC-MSCs’ proliferation and significantly enhanced the promoting effect of OMD on gene expression and protein secretion of osteogenic differentiation markers, calcium and phosphorous concentration, and mineralized matrix formation. …”
Get full text

Ultrasound and histopathological assessment of benign, borderline, and malignant thyroid tumors in pediatric patients: an illustrative review and literature overview by Dominika Januś, Dominika Januś, Monika Kujdowicz, Monika Kujdowicz, Aleksandra Kiszka-Wiłkojć, Aleksandra Kiszka-Wiłkojć, Konrad Kaleta, Anna Taczanowska-Niemczuk, Anna Taczanowska-Niemczuk, Jan Radliński, Kamil Możdżeń, Zuzanna Nowak, Wojciech Górecki, Wojciech Górecki, Jerzy B. Starzyk, Jerzy B. Starzyk

“…Future studies utilizing artificial intelligence (AI) to predict clinical outcomes in thyroid nodule diagnostics may offer new advancements, particularly given the increasing number of pediatric patients with solid thyroid lesions.…”
Get full text

Spline approximation of multivalued functions in linear structures routing by D. A. Karpov, V. I. Struchenkov

“…The main difference here consists in the impossibility of assuming in advance the number of spline elements when designing the routes. …”
Get full text

Endosperm culture-based allotriploid hybrid production from an interspecific cross of Haemanthus spp.: new insights into polyploidization and hybridization by Arisa Nakano, Masahiro Mii, Yoichiro Hoshino

“…These findings contribute to plant breeding strategies and advance our understanding of hybridization, polyploidization, and allopolyploid plant development.…”
Get full text

A digital intervention to reduce home-office workers’ sedentary behaviour: protocol for the evaluation of the Click2Move programme, a cluster randomised controlled trial by Judit Bort-Roig, Iris Parés-Salomón, Bette Loef, Cristina Vaqué-Crusellas, Alan Coffey, Arnau Gustems-Morral, Anna M. Señé-Mir, Izabela Luznik, Maja Pajek, Kieran P. Dowd, Anna Puig-Ribera, Karin I. Proper

“…Secondary outcomes will include device-based (activPAL3TM) and self-reported (Global Physical Activity Questionnaire and Workforce Sitting Questionnaire) physical activity and sedentary behaviour; self-reported musculoskeletal disorders (Standardised Nordic Questionnaire) and pain (Numeric Rating Scale); self-reported presenteeism and absenteeism (Health and Work Performance Questionnaire), job satisfaction (Need for Recovery scale) and fatigue (single-item 5-point Likert scale). …”
Get full text

Preparation For Flight: The Physical Profile of Pre-Professional and Professional Circus Artists in the United States by Stephanie J Greenspan, Melanie I Stuckey

“… # Conclusion These normative values for physical characteristics and functional performance in pre-professional and professional circus artists may be used to guide screening for readiness to participate in advanced training or performance, return to performance after injury, and the development of targeted strength and conditioning programs…”
Get full text

Automatic summarization of cooking videos using transfer learning and transformer-based models by P. M. Alen Sadique, R. V. Aswiga

“…As there is a growing need for easy-to-follow recipes made from cooking videos, researchers are looking on the process of automated summarization using advanced techniques. One such approach is presented in our work, which combines simple image-based models, audio processing, and GPT-based models to create a system that makes it easier to turn long culinary videos into in-depth recipe texts. …”
Get full text

A workplace-based HIV self-testing intervention as a determinant for self-testing knowledge, beliefs, and use among unskilled workers in Wakiso Uganda by Gerald Mukisa Nsereko, Khamisi Musanje, Eron Robinah Ayesiga, Loyce Kiiza Kobusingye, Rhoda Namubiru, Moses Sempala, Christine Kiwala, Martin Mabunda Baluku

“…Conclusions Efforts should be directed toward advocating for frequent knowledge sharing about self-testing such as this study has provided among unskilled working populations in Uganda. …”
Get full text

KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitors by Linyan Tian, Chengming Liu, Sufei Zheng, Huiyang Shi, Fang Wei, Wenxin Jiang, Yucheng Dong, Haiyan Xu, Enzhi Yin, Nan Sun, Jie He, Yan Wang

“…Abstract Background KRAS-G12C inhibitors mark a notable advancement in targeted cancer therapies, yet identifying predictive biomarkers for treatment efficacy and resistance remains essential for optimizing clinical outcomes. …”
Get full text

The Role of Non-Governmental Organisations (NGOs) on the Socio¬economic Transformation of Rural Areas in Nyarusiza Sub-County Kisoro District. by Izabayo, Joan

“…The study concludes that the NGOs in the Nyarusiza sub-county, Kisoro district, like to manifest themselves as advocates of social change. The priority for achieving effective social change is to eliminate all forms of discrimination in society, and the empowerment of women is the first step. …”
Get full text

Assessing the Role of MBIFCT as a Non-Governmental Organisations (NGO) in Socio-Economic Transformation of Rural Areas in Gitenderi Parish Nyarusiza Sub-County Kisoro District. by Kwebiha, Alex

“…In chapter four showed the findings of the study obtained from the field interpreting the results analyzing basing on the specific objectives of the study and chapter five portrayed the summary of findings, the study concludes that the MBIFCT as NGOs in Nyarusiza sub-county Kisoro district like to manifest themselves as advocates of social change. For bringing effective social change the first priority is to eradicate all kinds of discrimination in the society, empowerment of women is the first thing to do. …”
Get full text

Political Interference and Social Service Delivery in Kanaba Sub-County Kisoro District. by Tumushime, Bosco

“…The study found out that the Demand for power by politicians, the Government's ability to grow the economy, the Need of political distribution, Failure to pay attention to politics on service delivery, Redistribution of social justice, Inequality, and uneven advances in education and training, Demand for democracy using social service delivery protests and Government legitimacy respectively were the major causes of political interferences to service delivery. …”
Get full text

Exploring the Role of Social Workers in Addressing Health Disparities Among Maginalised Population in Kabale District. by Asasira, Precious

“…According to objective three, it was found that respondents from Kabale district Local government that the possible measures to the challenges faced by social workers in addressing the health disparities among marginalized populations include; stopping Family Violence, advancing long and Productive Lives, Create Social Responses to a Changing Environment, eradicate Social Isolation, harness Technology for social good, reduce Extreme Economic Inequality and others .…”
Get full text

Factors Affecting Teachers in Implementing the Thematic Curriculum in Primary Schools in Uganda: A Case Study of Butogota Primary School Kanungu District. by Twinomujuni, Dorothy

“…The findings showed that on factors affecting teachers in implementing the thematic curriculum, the majority of the respondents 60% mentioned thematic curriculums can feel prescriptive as factors affecting teachers in implementing thematic curriculum, it was also found that the majority of respondents 45% of teachers face challenges in implementing thematic curriculums, which often require a variety of engaging materials and activities and the majority 23% of respondents mentioned advocating for teachers to work together in developing thematic units and sharing resources as possible solutions to the challenges facing teachers in implementing the thematic curriculum. …”
Get full text

Girl-Child Empowerment and Socio-Economic Welfare in Urban Southwestern Uganda: A case study of Kanungu Town Council, Kanungu District. by Ian, Byoonanebye

“…In addition, it was found out that, the performance of girl-child interventions included formal education for girls through universal primary and secondary education has enabled them to advance their education career, being aware of family planning services. …”
Get full text

A Program for Master of Science in Environment and Natural Resources (MENR) by Kabale University

“…This will be fulfilled through working closely with rural farmers, research and educational programmes that link advances in fundamental and applied biological sciences to indigenous and contemporary development issues. …”
Get full text

Stable isotope ecology of Quaternary cervid and bovid species in Southeast Asia with implications for wildlife conservation by Sanah Shaikh, Hervé Bocherens, Kantapon Suraprasit

Get full text

Natural biopolymers in edible coatings: Applications in food preservation by Arun Karnwal, Gaurav Kumar, Rattandeep Singh, Manickam Selvaraj, Tabarak Malik, Abdel Rahman Mohammad Al Tawaha

Get full text