Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

“…Cyclin Dependent Kinase inhibitors (CDKi) are at the front-line of novel targeted treatments for multiple cancers and the CDK4/6 specific inhibitor palbociclib has been pre-clinically identified as an effective option for MB cells. …”
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Un proyecto comprensivo para la investigación y conservación de perezosos en cacaotales de Costa Rica  by Christopher Vaughan

“… El perezoso de dos dedos (Choloepus hoffmanni) y el de tres dedos (Bradypus variegatus), hoy considerados símbolos nacionales de Costa Rica, fueron estudiados durante 13 años (2004-2016) en una finca de cacao y sus alrededores dentro del proyecto “Theobroma cacao: Biodiversidad en doseles forestales totales y parciales”. …”
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The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey) by Øyvind Helgeland, Jens K. Hertel, Anders Molven, Helge Ræder, Carl G. P. Platou, Kristian Midthjell, Kristian Hveem, Ottar Nygård, Pål R. Njølstad, Stefan Johansson

“…Two adjacent regions upstream CDKN2B on chromosome 9p21 have been associated with type 2 diabetes (T2D) and progression of cardiovascular disease (CVD). …”
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E-Kaynak Lisanslarının Analizi ve Anlaşmaların Müzakere Edilme Süreci by Sacit Arslantekin, Damla Yilmaz

“…Bulgular: ANKOS TRNLS ilkelerinin %46’sı, LIBLICENSE Model Lisansı önerilerinin ise %48’i Türkiye’deki nihai lisanslara yansıtılmıştır. …”
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POVERTY AND NATIONAL SECURITY: AN OVERVIEW OF NIGERIA’S FOURTH REPUBLIC by ADAMU MOHAMMED

“… Nigeria is now facing significant internal security difficulties, such as the Niger Delta militancy in the South-South geopolitical zone that includes Bayelsa and Rivers, and the Boko Haram insurgency in the northeastern regions of Borno, Yobe, and Adamawa. …”
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Genetic Markers Can Predict Chondrogenic Differentiation Potential in Bone Marrow-Derived Mesenchymal Stromal Cells by Masami Kanawa, Akira Igarashi, Katsumi Fujimoto, Yukihito Higashi, Hidemi Kurihara, Masaru Sugiyama, Tania Saskianti, Yukio Kato, Takeshi Kawamoto

“…The expression levels of CDKN2D, CD74, and TGM2 were >10-fold higher in highly potent MSCs (ilium MSCs) than in MSCs with limited potential (jaw MSCs). …”
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Os Cadernos Nietzsche by Vânia Dutra de Azeredo, Eduardo Nasser

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Zinc-Nickel Codeposition in Sulfate Solution Combined Effect of Cadmium and Boric Acid by Y. Addi, A. Khouider

“…In solution, cadmium inhibits the zinc ion deposition and suppresses it when deposition potential value is more negative than −1.2 V. Low concentration of CdSO4 reduces the anomalous nature of Zn-Ni deposit. …”
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A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases by Anthony C. Nichols, Michelle Chan-Seng-Yue, John Yoo, Sumit K. Agrawal, Maud H. W. Starmans, Daryl Waggott, Nicholas J. Harding, Samuel A. Dowthwaite, David A. Palma, Kevin Fung, Bret Wehrli, S. Danielle MacNeil, Philippe Lambin, Eric Winquist, James Koropatnick, Joe S. Mymryk, Paul C. Boutros, John W. Barrett

“…The primary tumor and blood underwent exome sequencing which revealed deletions in CDKN2A as well as PPP1R13B, which induces p53. A damaging nonsynonymous mutation was noted in EP300, a histone acetylase which plays a role in cellular proliferation. …”
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Investigation and Identification of let-7a Related Functional Proteins in Gastric Carcinoma by Proteomics by Yimin Zhu, Xingyuan Xiao, Lairong Dong, Zhiming Liu

“…Furthermore, the different expression levels of the partial proteins (CDKN1, Spk2 and Fibronectin) were confirmed by western blot analysis. …”
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From Melanocyte to Metastatic Malignant Melanoma by Bizhan Bandarchi, Linglei Ma, Roya Navab, Arun Seth, Golnar Rasty

“…There is a complex interaction of environmental (exogenous) and endogenous, including genetic, risk factors in developing malignant melanoma. 8–12% of familial melanomas occur in a familial setting related to mutation of the CDKN2A gene that encodes p16. The aim of this is to briefly review the microanatomy and physiology of the melanocytes, epidemiology, risk factors, clinical presentation, historical classification and histopathology and, more in details, the most recent discoveries in biology and genetics of malignant melanoma. …”
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Quem foi a profes sora Anna Averbuch? Educadora, Profissional Competente, Amiga, Colega e Irmá by Estela Kaufman Fainguelernt, Franca Cohen Gottlieb

“…Estudou  no Liceu Francés,  no Colégio Benett, e fez o Curso Complementar, absorvido  pelo Colégio Pedro II.   Desde  cedo, sentiu sua atracáo para o magistério,  com um particular  interesse  no ensino  de Matemática, por  isto  ingressou  na Faculdade  Nacional  de Filosofía, da Universidade do Brasil, cursando Licenciatura e Bacharelado  em Matemática. …”
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Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma by Li Yan, Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj, Kathryn Graz, Elnaz Naderi, Jianhong Chen, Mourad Wagdy Ali, Puya Gharahkhani, Xiang Shu, Kenneth Offit, Pari M. Shah, Hans Gerdes, Daniela Molena, Amitabh Srivastava, Stuart MacGregor, Claire Palles, René Thieme, Michael Vieth, Ines Gockel, Thomas L. Vaughan, Johannes Schumacher, Matthew F. Buas

“…Rs3217992 maps to the CDKN2B 3′ UTR and reportedly disrupts microRNA-mediated repression. …”
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Evaluación del crecimiento de Cedrela odorata L. en sistemas agroforestales con café en Pérez Zeledón, Costa Rica by David Carvajal-Arroyo, Rafael Murillo-Cruz, Mariela González Rojas, William Fonseca-González

“…Se generaron 14 modelos que predicen el volumen total por árbol a partir del DAP, la edad y la altura; para el conjunto de edades (de 1 a 20 años) y para rangos (cada 5 años). …”
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AVALIAÇÃO DE CARACTERÍSTICAS ERGONÔMICAS, CAPACIDADE PARA O TRABALHO E DESCONFORTO MÚSCULO-ESQUELÉTICO NA CENTRAL DE DISTRIBUIÇÃO DE MATERIAIS DE UM HOSPITAL DE CLÍNICAS NO ESTADO... by Felipe Nunes Dionísio, Patrícia Aidê Bortolotti, Andreza A. Aleixo, Danyelle Cristina Silva Pelet, Isabel A. P Walsh, Juliana Lemos Silva, Dernival Bertoncello

Subjects: “…análise ergonomia do trabalho…”
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Identification of Important Genes of Keratoconus and Construction of the Diagnostic Model by Lin Wang, Yuqing Wang, Juan Liu, Wencheng Zhao

“…We took 8 DEGs as the final optimal combination of DEGs: AREG, BBC3, DUSP2, map3k8, Smad7, CDKN1A, JUN, and LIF. Conclusion. Abnormal cell proliferation, apoptosis, and autophagy defects are related to KC, which may be the etiology and potential target of KC.…”
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Facade decoration in the architecture of Dragiša Brašovan and Milan Zloković by Novaković Aleksa

“…The stylistic development of ornamentation was conditioned by Academicist and Classicist tendencies on the one hand, and the emergence and popularization of Art Deco and Modernism on the other. This paper takes a representative selection of facade decorations from significant and distinguished buildings and competition projects created by Dragiša Brašovan and Milan Zloković during the 1920s and 1930s, with the aim of analyzing the contribution of sculptors whose creative work enriched their facades. …”
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Confronting the cataracts of whiteness to see the invisible: reflections on the transmission and reception of the Bible in post-apartheid South Africa by J. Kok

“…Jennings, R. Ellison, and Steven Biko, as well as other notable figures, to critically reflect on the role of biblical scholarship in the process of restoring historically marginalised voices within the context of past injustices. …”
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Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments by Beihui He, Zheng Chen, Yunmeng Nie, Minmin Luo, Sumei Xu, Junbin Yan, Zhiyun Chen

“…The results of WB and qRT–PCR showed that the expression of PTGS2, JUN, MYC, and CDKN1A was higher in NASH rats than in normal rats and decreased after SQP treatment. …”
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Impact of type 2 diabetes variants identified through genome-wide association studies in early-onset type 2 diabetes from South Indian population by Samuel Liju, Manickam Chidambaram, Viswanathan Mohan, Venkatesan Radha

“…We confirm the association of the HHEX variant rs1111875 with EOT2D in this South Indian population and also the association of CDKN2A/2B (rs7020996) and TCF7L2 (rs4506565) with EOT2D. …”
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