Inpatient dialectical behavior therapy combined with trauma-focused therapy for PTSD and borderline personality disorder symptoms: study design of the naturalistic trauma therapy s... by Annemieke C. Kamstra, Annemieke C. Kamstra, Sybolt O. de Vries, Maarten F. Brilman, Petty Vasilev, Manna A. Alma, Antoinette D. I. van Asselt, Antoinette D. I. van Asselt, Mia De Wolf, Robert A. Schoevers, Frederike Jörg

“…Secondary outcomes are social functioning, quality of life, borderline and cluster C personality disorder symptoms as treatment predictors, treatment trajectories, clients’ experiences and health economic consequences.MethodsThe naturalistic, longitudinal Trauma Therapy Study is conducted from January 2019 until May 2025 in a mental healthcare center in the Netherlands. …”
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Hypoxia-Elicited Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Myocardial Infarction by Promoting Angiogenesis through the miR-214/Sufu Pathway by Lianbo Shao, Yihuan Chen, Jingjing Li, Jingfan Chao, Ziying Yang, Yinglong Ding, Han Shen, Yueqiu Chen, Zhenya Shen

“…Method. huMSCs were preconditioned with hypoxia (1% O2 and 5% CO2 at 37°C for 48 hours), and their sEVs were isolated using the Total Exosome Isolation reagent kit. To explore the role of miR-214 in MSC-derived sEVs, sEVs with low miR-214 expression were prepared by transfecting miR-214 inhibitor into huMSCs before hypoxia pretreatment. …”
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Effectiveness, cost-effectiveness and return on investment of individual placement and support compared with traditional vocational rehabilitation for individuals with severe menta... by Johanna Maria van Dongen, Philippe Delespaul, Frederieke Schaafsma, Jaap van Weeghel, Johannes Anema, Miljana Vukadin, Wim Zwinkels, Marcel Spijkerman, Marloes de Graaf-Zijl

“…Based on these results, the implementation of IPS by a wide scale reimbursement strategy could be promoted to enhance sustainable participation in competitive employment in these individuals. Future economic evaluations should strive for a more robust sample size and a long follow-up period.…”
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Molecular-genetic approaches to species identification of platyhelminthes of the genus <i>Ligophorus</i> (Monogenea) parasitising flathead mullet by E. A. Vodiasova, E. S. Chelebieva, O. V. Shikhat, D. M. Atopkin, E. V. Dmitrieva

“…The developed genotyping protocols can be used not only to distinguish two species of Ligophorus from flathead mullet in ecological studies and veterinary practice but also for further development of similar approaches for other monogeneans, among which there are many pathogenic species.…”
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Chemical analysis of buffalo meat in a self-consumption system in northeastern of Argentina by Gladis Rébak, Gladys Obregón, Diego Gómez, Laura Vázquez-Acosta, Mariano Pino, Julia Obregón, Rosa Molina, Victoria Cantero, Luz Segovia-Espinola

“…The exploitation of buffaloes is presented as an alternative for meat production, as it adapts to special agro-ecological conditions due to waterlogging of the land, the presence of low-digestibility pastures and ectoparasites in which beef cattle do not always express their maximum potential. …”
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Population Dynamics of the Crocodile Shark, <i>Pseudocarcharias kamoharai</i>, in the Tropical Equatorial Pacific Ocean, Ecuador by Marcos Douglas Calle-Morán, Eugenio Alberto Aragón-Noriega, Ana Rosa Hernández-Téllez, Emigdio Marín-Enríquez, Javier Tovar-Ávila, Juan Francisco Arzola-González, Jorge Payán-Alejo

“…Based on the biology and ecology of this species, all models applied in this study showed that <i>P. kamoharai</i> had low natural and fishing mortality rates and moderate total mortality; its exploitation rate exceeded the fishing limits. …”
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Environmental and health risk assessment of polycyclic aromatic hydrocarbons and toxic elements in the red sea using Monte Carlo simulation by F. Alshaima Sayed, Mohamed Hamdy Eid, Ahmed M. El-Sherbeeny, Gouda Ismail Abdel-Gawad, Essam A. Mohamed, Mostafa R. Abukhadra

“…Elevated total organic carbon (TOC) levels in Suez Bay indicated aggravated organic pollution, exacerbated by oil rigs and refineries. The ecological risk assessment highlighted substantial risks, particularly in Suez, necessitating immediate interventions to combat PAH contamination and preserve the environmental balance of the Red Sea. …”
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Halophilic bacteria of salt lakes and saline soils of the Peri-Caspian lowland (Republic of Daghestan) and their biotechnological potential by E. A. Khalilova, S. T. Kotenko, E. A. Islammagomedova, A. A. Abakarova, N. A. Chernyh, D. A. Aliverdiyeva

“…The data obtained expanded the understanding of the diversity and ecological significance of denitrifying bacteria in the functioning of arid ecosystems and make it possible to identify strains producing enzymes of industrial importance.…”
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Exploring the multifaceted roles of Sonneratia apetala and Nipa fruticans in coastal habitat restoration and bioactive properties discovery by Sabina Yasmine, Rezwana Zaman Proma, Md. Ripaj Uddin, Mohammad Saydur Rahman, Md. Hamedul Islam, Muhammad Abdullah Al Mansur, AHM Shofiul Islam Molla Jamal, Abu Yousuf, Md. Hasnain Mustak, Sarker Kamruzzaman, M. Mahboob Ali Siddiqi

“…Background: Sonneratia apetala and Nipa fruticans are mangrove species, perennial wild plants with significant therapeutic, ecological, and environmental value. They are extensively utilized by the local communities of the Sundarbans and coastal estuaries for various purposes. …”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…Gastrointestinal nematodes (GINs) inflict significant economic losses on sheep and goat farming globally due to reduced productivity and the development of anthelmintic resistance. …”
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Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells by Chu-An Wang, Ya-Chin Hou, Yi-Kai Hong, Yu-Jing Tai, Chieh Shen, Pei-Chi Hou, Jhao-Lin Fu, Cheng-Lin Wu, Siao Muk Cheng, Daw-Yang Hwang, Yung-Yeh Su, Yan-Shen Shan, Shaw-Jenq Tsai

“…Digital spatial profiling analysis of PDAC samples demonstrates the colocalization of TIMP-1high macrophages and CD63high cancer cells. …”
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Emergencia dentaria a los 12 años en escolares de Montevideo: Estudio transversal by Martin Zepedeo, Valentina Colistro, Licet Alvarez, Luana Severo Alves, Marisa Maltz, Anunzziatta Fabruccini Fager

“… Objetivos: Conocer la secuencia y cronología de la emergencia dentaria en escolares montevideanos de 12 años, con énfasis en la erupción del segundo molar en relación con el recambio de las piezas ubicadas mesialmente.  …”
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Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma by Lijuan Wang, Qian He, Weijun Qin, Xiyu Song, Yumeng Zhu, Wenwen Geng, Jianhua Jiao, Hongjiao Liu, Ruo Chen, Xiuxuan Sun, Jiejie Geng, Zhinan Chen

“…This group of Treg cells has stronger immunosuppressive function and was associated with a worse prognosis in ccRCC cohorts. They were colocalized with MRC1+FOLR2+ tumor-associated macrophages (TAMs) at the tumor-normal interface to form a positive feedback loop, maintaining a synergistic procarcinogenic effect. …”
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Identification of CENPM as a key gene driving adrenocortical carcinoma metastasis via physical interaction with immune checkpoint ligand FGL1 by Cunru Zou, Yu Zhang, Chengyue Liu, Yaxin Li, Congjie Lin, Hao Chen, Jiangping Hou, Guojun Gao, Zheng Liu, Qiupeng Yan, Wenxia Su

“…FGL1, important components of ECM signalling and immune checkpoint ligand of LAG3, were downregulated following CENPM silence, overexpressed in human advanced ACC samples, and colocalized with CENPM. Physical interaction between CENPM and FGL1 was identified. …”
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Errores innatos de la inmunidad en pacientes de Sancti Spíritus, Cuba. 2022. by María del Carmen Chávez Alfonso, José Luis Marcelo Pentón, Yralys Naranjo Herrera, Valia Concepción Ulloa, Dayana Monteagudo García, Ernesto Gabriel Caraballosa Yera

“…Introducción: El Registro Cubano de Inmunodeficiencias Primarias fue creado en el 2009 y tiene como objetivo fundamental conocer la epidemiología de estas enfermedades en nuestro medio. …”
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PERCEPCIÓN DEL ÍNDICE DE MASA CORPORAL Y LOS HÁBITOS ALIMENTARIOS Y DE ACTIVIDAD FÍSICA by Mónica Lizbeth Bautista Rodríguez, Rosalinda Guadarrama Guadarrama, Marcela Veytia-López, Bárbara de los Ángeles Pérez Pedraza

“…Por lo que, la educación sobre la imagen corporal realista y los hábitos saludables son necesarios para prevenir problemas de salud. Objetivo: conocer la asociación de la percepción del índice de masa corporal y los hábitos alimentarios y de actividad física. …”
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Astrocytic NLRP3 cKO mitigates depression-like behaviors induced by mild TBI in mice. by Hui-Tao Miao, Jun Wang, Jing-Jing Shao, Rong-Xin Song, Wen-Guang Li, Jian-Kai Sun, Shi-Yan Jia, Dong-Xue Zhang, Xiao-Ming Li, Jian-Yong Zhao, Li-Min Zhang

“…Results: Our findings indicated that astrocyte-specific NLRP3 KO decreased cleaved caspase-1 colocalized with astrocytes, decreased pathogenic astrocytes and increased Postsynaptic density protein 95 (PSD95) intensity, and significantly alleviated mild TBI-induced depression-like behaviors. …”
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Diseño y manufactura de carrocería de vehículo eléctrico con paneles solares para uso urbano by Abisai Jaime Reséndiz Barrón, Miguel Aarón Ramos Pérez, Alejandro Salas Flores, Francisco Javier García Rodriguez

“…Se estima el área irradiada por el sol, con la finalidad de colocar paneles solares flexibles sobre el capó y el toldo del VE, y conocer su contribución a la autonomía energética del VE. …”
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Tumor-associated-fibrosis and active collagen-CD44 axis characterize a poor-prognosis subtype of gastric cancer and contribute to tumor immunosuppression by Yingqi Yang, Haohan Sun, Hongkai Yu, Luyao Wang, Chang Gao, Haokun Mei, Xiaomeng Jiang, Minghui Ji

“…Consensus clustering identified a gastric cancer subtype characterized primarily by fibrosis, and various methods such as pseudotime analysis, CellChat analysis and Colocalization analysis were used to explore its mechanisms. …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…The accumulation of GM3 colocalized with Aβ plaques in aged APP/PS1 mice and correlated with Hexa gene expression, suggesting that ganglioside degradation is a mechanism for the accumulation of GM3. …”
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