The role of mitochondria-related genes and immune infiltration in carotid atherosclerosis: identification of hub targets through bioinformatics and machine learning approaches by Dan Liu, Kun Guo, Min Li, Xiaochen Yu, Xue Guan, Xiuru Guan

“…These findings may provide new insights into therapeutic monitoring and prognosis evaluation.…”
Get full text

Predicting the infecting dengue serotype from antibody titre data using machine learning. by Bethan Cracknell Daniels, Darunee Buddhari, Taweewun Hunsawong, Sopon Iamsirithaworn, Aaron R Farmer, Derek A T Cummings, Kathryn B Anderson, Ilaria Dorigatti

“…Despite these challenges, the best performing machine learning algorithm achieved 76.3% (95% CI 57.9-89.5%) accuracy on the out-of-sample test set in predicting the infecting serotype from PRNT data. …”
Get full text

Shared pathogenesis in polycystic ovaries and rheumatoid arthritis: an analysis of key genes and pathways by Yingying Ji, Pengcheng Xia, Yan Wang, Yang Liu, Feng Wang, Fenggang Sun, Qiang Feng, Qingbin Ni, Yi Li

“…Gene Ontology (GO) and KEGG pathway enrichment analyses were performed to understand the biological processes and pathways associated with the differentially expressed genes (DEGs). Protein interaction analysis, machine learning algorithms, and validation analyses were employed to identify core genes with potential diagnostic value. …”
Get full text

Identification and validation of biomarkers, construction of diagnostic models, and investigation of immunological infiltration characteristics for idiopathic frozen shoulder by Han-tao Jiang, Li-ping Shen, Meng-Qi Pang, Min-jiao Wu, Jiang Li, Wei-jie Gong, Gang Jin, Rang-teng Zhu

“…At the outset, we conducted differential expression analysis, weighted gene co-expression network analysis (WGCNA), and utilized the cytoHubba plugin, complemented by two machine learning algorithms, receiver operating characteristic (ROC) analysis, and expression level evaluation to identify biomarkers for FS. …”
Get full text

Identification and Validation of Key Genes Involved in the Coupling of Mitochondria-Associated Endoplasmic Reticulum Membrane in Hemorrhoidal Disease by Mao L, Rao Z, Wang Y, Yang J, He J, Zheng Z, Chen L

“…Additionally, CIBERSORT algorithms were utilized to evaluate immune cell infiltration abundance, differences, and correlations in the samples. …”
Get full text

A Robust Gaze Estimation Approach via Exploring Relevant Electrooculogram Features and Optimal Electrodes Placements by Zheng Zeng, Linkai Tao, Hangyu Zhu, Yunfeng Zhu, Long Meng, Jiahao Fan, Chen Chen, Wei Chen

“…Afterward, quantities of informative features to characterize physiological information of eye movement from the temporal-spectral domain are extracted from the seven differential channels. Methods and procedures: To select the optimum channels and relevant features, and eliminate irrelevant information, a heuristical search algorithm (i.e., forward stepwise strategy) is applied. …”
Get full text

Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients by David Dora, Peter Revisnyei, Peter Revisnyei, Alija Pasic, Gabriella Galffy, Edit Dulka, Anna Mihucz, Brigitta Roskó, Sara Szincsak, Anton Iliuk, Glen J. Weiss, Zoltan Lohinai, Zoltan Lohinai

“…Internal validation was performed using the Random Forest (RF) machine learning (ML) algorithm. RF was validated with a non-linear Bayesian ML model. …”
Get full text

Development of a machine learning prediction model for loss to follow-up in HIV care using routine electronic medical records in a low-resource setting by Tamrat Endebu, Girma Taye, Wakgari Deressa

“…The performance of each algorithm was evaluated through a 10-fold cross-validation approach. …”
Get full text

Selection of molecular markers for genetic certification of <i>Triticum aestivum</i> by M. A. Samarina, D. S. Uliyanov, T. D. Mokhov, Ya. S. Meglitskaya, P. Yu. Krupin, G. I. Karlov, P. N. Kharchenko, S. I. Voronov, N. V. Davydova, M. G. Divashuk

“…In connection with these limitations, the purpose of the current work was to develop approaches for the selection of molecular genetic mic- rosatellite markers (SSR markers) to differentiate common wheat varieties. In accordance with the purpose, there has been conducted a literature review regarding methods for genetic certification and evaluation of the diversity of spring common wheat based on polymorphism of microsatellite loci, and there has been generated a set of Triticum aestivum genome assemblies from the NCBI Gen Bank. …”
Get full text

Deep learning-based framework for Mycobacterium tuberculosis bacterial growth detection for antimicrobial susceptibility testing by Hoang-Anh T. Vo, Sang Nguyen, Ai-Quynh T. Tran, Han Nguyen, Hai Bich Ho, Philip W. Fowler, Timothy M. Walker, Thuy Thi Nguyen

“…Automated Mycobacterial Growth Detection Algorithm (AMyGDA) is a software package that uses image processing techniques to read plates, but struggles with plates that exhibit low growth or images of low quality. …”
Get full text

Detection of litchi fruit maturity states based on unmanned aerial vehicle remote sensing and improved YOLOv8 model by Changjiang Liang, Changjiang Liang, Dandan Liu, Dandan Liu, Weiyi Ge, Weiyi Ge, Wenzhong Huang, Wenzhong Huang, Yubin Lan, Yubin Lan, Yubin Lan, Yongbing Long, Yongbing Long, Yongbing Long, Yongbing Long

“…However, existing studies are largely limited to the binary classification of immature and mature fruits, lacking dynamic evaluation and precise prediction of maturity states. …”
Get full text

Advancements in Microwave Bone Imaging: Tomographic Reconstruction of an Anthropomorphic Calcaneus Phantom Using a Specialized Imaging Prototype for Bone Health Applications by Alessia Cannata, Adnan Elahi, Martin O'Halloran, Marco Pasian, Simona Di Meo, Giulia Matrone, Bilal Amin

“…The evaluation and characterization of microwave imaging (MWI) prototype along with the optimization of imaging algorithm is a precursor step before the clinical study to measure in vivo dielectric properties. …”
Get full text

MODERN APPROACHES TO CLINICAL AND LABORATORY DIAGNOSTICS OF RHEUMATOID ARTHRITIS EARLY ONSET by D. G. Rekalov, S. Y. Dotsenko, A. V. Kylinich

“…This review presents the data of the importance of differentiation of several stages of RA in relation to the time factor. …”
Get full text

Electronic nose and machine learning for modern meat inspection by Ivan Shtepliuk, Guillem Domènech-Gil, Viktor Almqvist, Arja Helena Kautto, Ivar Vågsholm, Sofia Boqvist, Jens Eriksson, Donatella Puglisi

“…Based on the consensus of preliminary decisions from each individual sensor element, the algorithm effectively determined the final status of the meat. …”
Get full text

An immunotherapy guide constructed by cGAS-STING signature for breast cancer and the biofunction validation of the pivotal gene HOXC13 via in vitro experiments by Zhenling Dai, Ziqun Gu, Rongrong Shen, Jingshuai Wang

“…Notably, this 11-gene signature also predicted the sensitivity of breast cancer to both conventional and immune therapies, aligning closely with predictions from the OncoPredict algorithm. Further, in-vitro experiments confirmed the regulatory role of HOXC13, one of the 11 genes, in the cGAS-STING pathway. …”
Get full text

Host Circulating Immunometabolism-Associated Biomarkers for Early Diagnosis of Active Tuberculosis: Multi-Omics Screening with Experimental Validation by Yang Z, Dong Y, Shang Y, Li H, Ren W, Li S, Pang Y

“…Correlation analysis between gene expression and immune cell infiltration was performed using the CIBERSORT algorithm. Single-cell RNA-seq analysis was performed to explore the expression of hub genes in the different immune cells.Results: In this study, we first obtained 41 differentially expressed metabolism-related genes in active TB patients compared to HCs through bulk transcriptomic analysis. …”
Get full text

THE RELATIONSHIP BETWEEN THE INDIVIDUAL GENETICALLY DETERMINED FACIAL PROFILE OF PATIENTS WITH A DISTAL OCCLUSION (ENGLE CLASS II) AND THE TYPE OF GROWTH OF THEIR FACIAL SKULL AND... by S.I. Doroshenko, O.Y. Opekha, V.V. Volkova

“…Jarabak methods has enabled a more detailed diagnosis of distal occlusion (Class II malocclusion) and the development of a comprehensive treatment algorithm with improved outcome prediction. …”
Get full text

ATP6V0A4 as a novel prognostic biomarker and potential therapeutic target in oral squamous cell carcinoma by Xiaopu Gao, Jiamin Zhou, Yu Qiao, Chuyin Lin, Guanxiong Zhang, Qiuyu Wu, Zhikang Su, Qianji Zhang, Songkai Huang

“…Methods This study initially integrated TCGA and GEO databases for cross-platform differential gene screening. A prognostic model was constructed using univariate Cox regression and LASSO regression, complemented by random forest algorithms to identify core genes. …”
Get full text

Identification of anoikis-related genes classification patterns and immune infiltration characterization in chronic rhinosinusitis with nasal polyps based on machine learning by Ziqi Chen, Lingmei Qu, Qing Hao, Shuang Teng, Shuo Liu, Qin Wu, Hongtian Yi, Xianji Shen, Liang Li, Zhaonan Xu, Yanan Sun

“…Immune cell infiltration was analysed using the CIBERSORT algorithm. CRSwNP samples were classified via consensus clustering. …”
Get full text

Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery by Wanli Ma, Xinyi Liu, Ran Yu, Jiannan Song, Lina Hou, Ying Guo, Hongwei Wu, Dandan Feng, Qi Zhou, Haibo Li

“…Subsequently, functional enrichment analyses, including GO, KEGG, and GSEA, were performed to explore the biological significance of the GARGs.A PPI network was constructed to identify core genes, and immune infiltration analysis was performed using the ssGSEA algorithm. To further evaluate immune microenvironmental features, unsupervised clustering was applied to identify immunological subgroups. …”
Get full text