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  1. 601

    Identification and analysis of the endoplasmic reticulum stress hub genes in sepsis-associated ARDS by Ling Gao, Tingting Liu, Xiaoyan Li

    Published 2025-08-01
    “…The aim of this study was to identify and analyze hub genes related to ERS in sepsis-associated ARDS using bioinformatics and machine learning algorithms, which may serve as diagnostic markers and therapeutic targets. …”
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    Article
  2. 602

    Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays. by Thomas Sanford, Paul H Chung, Ariel Reinish, Vladimir Valera, Ramaprasad Srinivasan, W Marston Linehan, Gennady Bratslavsky

    Published 2011-01-01
    “…<h4>Purpose</h4>To evaluate the accuracy of the sub-classification of renal cortical neoplasms using molecular signatures.…”
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    Article
  3. 603

    From Biopsy to Diagnosis: Navigating Aggressive B-Cell Lymphomas in Practice by Georgian Halcu, Anca Evsei-Seceleanu, Mihai Cerbu, Marina Alina Bara, Andrei Turbatu, Mihail Constantin Ceausu

    Published 2025-05-01
    “…This review presents a practical method for differentiating DLBCL from other aggressive B-cell neoplasms, such as Burkitt lymphoma, B-lymphoblastic lymphoma, and mantle cell lymphoma. …”
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    Article
  4. 604

    Early detection of bacterial pneumonia by characteristic induced odor signatures by Kim Arnold, Alejandro Gómez-Mejia, Miguel de Figueiredo, Julien Boccard, Kapil Dev Singh, Serge Rudaz, Pablo Sinues, Annelies S. Zinkernagel

    Published 2024-12-01
    “…The detected VOCs were analyzed using a pre- and post-processing algorithm along with ANOVA and RASCA statistical evaluation methods. …”
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    Article
  5. 605

    Lactylation Modification as a Promoter of Bladder Cancer: Insights from Multi-Omics Analysis by Yipeng He, Lingyan Xiang, Jingping Yuan, Honglin Yan

    Published 2024-11-01
    “…Functional enrichment analysis, tumor microenvironment analysis, and treatment response evaluation were performed on the high- and low-risk groups. …”
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    Article
  6. 606

    Study on Energy Efficiency and Maintenance Optimization of Run-Out Table in Hot Rolling Mills Using Long Short-Term Memory-Autoencoders by Ju-Woong Yun, So-Won Choi, Eul-Bum Lee

    Published 2025-04-01
    “…By integrating the technical advantages of these two algorithms, a predictive maintenance model based on the LSTM-AE algorithm, named the Run-Out Table Predictive Maintenance Model (ROT-PMM), was developed. …”
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    Article
  7. 607

    Mechanistic role of miR-375 in regulating PDPK1 to promote progression of small bowel neuroendocrine tumors: a silico analysis by Tao Ren, Lu Zhou, Zhenlong Li, Mingmei Pan, Xueqiong Han

    Published 2025-06-01
    “…Enrichment and coexpression analyses were carried out for DEmRs. XGBoost algorithm was used to screening feature miRNAs. Module genes in SBNETs-related pathways were selected to construct regulated network for feature miRNAs. …”
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    Article
  8. 608

    Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

    Published 2025-07-01
    “…Subsequently, functional enrichment analysis was performed to clarify the biological functions of these genes. Machine learning algorithms were used to screen for the hub RA-RF differential expression genes, and then a Logistic Regression (LR) model was constructed. …”
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    Article
  9. 609

    A nicotinamide metabolism-related gene signature for predicting immunotherapy response and prognosis in lung adenocarcinoma patients by Meng Wang, Wei Li, Fang Zhou, Zheng Wang, Xiaoteng Jia, Xingpeng Han

    Published 2025-02-01
    “…Next, the MCP-counter, TIMER and ESTIMATE algorithms were utilized to comprehensively assess the immune microenvironmental profile of LUAD patients in different risk groups. …”
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    Article
  10. 610

    Identification of multiomics and immune infiltration-associated biomarkers for early gastric cancer: a machine learning-based diagnostic model development study by Kewei Du, Wenfei Hu, Shan Gao, Jianxin Gan, Chongge You, Shangdi Zhang

    Published 2025-05-01
    “…Methods We employed serum proteomics combined with bioinformatics to identify genes differentially expressed in the serum of non-metastatic GC patients. …”
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    Article
  11. 611

    Identification of Eye Diseases Through Deep Learning by Elena Acevedo, Dinora Orantes, Marco Acevedo, Ricardo Carreño

    Published 2025-04-01
    “…<b>Conclusions</b>: With the individual analysis of each metric, it can be observed that the proposed algorithm is capable of differentiating, first, images of healthy eyes from diseased ones and, second, adequately classifying eye diseases.…”
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    Article
  12. 612

    Network Resource Allocation Method Based on Awareness–Prediction Joint Compensation for Low-Earth-Orbit Satellite Networks by Hang Di, Tao Dong, Zhihui Liu, Shuotong Wei, Qiwei Zhang, Dingyun Zhang

    Published 2025-05-01
    “…Furthermore, an efficient, accelerated alternating-direction method of multipliers (ADMM) resource allocation algorithm is proposed with the aim of maximizing the satisfaction of service resources requirements. …”
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    Article
  13. 613

    LcProt: Proteomics‐based identification of plasma biomarkers for lung cancer multievent, a multicentre study by Hengrui Liang, Runchen Wang, Ran Cheng, Zhiming Ye, Na Zhao, Xiaohong Zhao, Ying Huang, Zhanpeng Jiang, Wangzhong Li, Jianqi Zheng, Hongsheng Deng, Yu Jiang, Yuechun Lin, Yun Yan, Lei Song, Jie Li, Xin Xu, Wenhua Liang, Jun Liu, Jianxing He

    Published 2025-01-01
    “…Feature selection was performed using differential expressed protein analysis, area under curve (AUC) evaluation and least absolute shrinkage and selection operator (LASSO) regression. …”
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    Article
  14. 614

    Back pain: from pathophysiological mechanisms and clinical features to modern approaches to therapy by N. V. Titova, Yu. N. Bezdolny, A. A. Slipko

    Published 2025-06-01
    “…When inflammatory pain patterns are present in the sacroiliac joints region, it is mandatory to rule out sacroiliitis within the spectrum of seronegative spondyloarthritis (including ankylosing spondylitis and others) using a specialized diagnostic algorithm. Muscle-tonic syndrome requires differentiation from myofascial pain syndrome, another common form of musculoskeletal pain, as they have fundamental differences in pathogenesis, clinical presentation and treatment approaches. …”
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    Article
  15. 615

    Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights. by Jincan Li, Shengyue Wang

    Published 2025-01-01
    “…This study aimed to develop an integrated epigenetic-based classification system and evaluate its prognostic value.<h4>Methods</h4>We performed multi-omics analysis on five independent cohorts totaling 1,103 AML patients. …”
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    Article
  16. 616

    Single cell transcriptomic analysis reveals tumor immune infiltration by macrophage cells gene signature in lung adenocarcinoma by Xiaotong Guo, Youjun Deng, Wenjun Jiang, Heng Li, Yisheng Luo, Huachuan Zhang, Hao Wu

    Published 2025-03-01
    “…The underlying mechanism was further elucidated through the application of GSEA, ESTIMATE, TIDE, and other bioinformatic algorithms. Results Single-cell atlas was described by analyze 29 scRNA-seq samples from 19 LUAD patients. …”
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    Article
  17. 617

    Comprehensive Analysis of the Role of Metabolic Features in Osteoporosis: A Multi-Omics Analysis by Chang S, Tao W, Shi P, Wu H, Liu H, Xu J, Chen J, Zhu J

    Published 2025-05-01
    “…Three machine learning algorithms were used to evaluate the diagnostic potential of metabolic signatures for OP.Results: A total of 402 significantly differentially expressed MRGs (DEMRGs) were identified in the transcriptome, and these DEMRGs were enriched in 11 metabolic pathways (P&lt; 0.05). …”
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    Article
  18. 618

    CytoLNCpred-a computational method for predicting cytoplasm associated long non-coding RNAs in 15 cell-lines by Shubham Choudhury, Naman Kumar Mehta, Gajendra P. S. Raghava

    Published 2025-05-01
    “…Correlation-based features combined with ML algorithms outperform LLM-based models, in the case of predicting differential lncRNA localization. …”
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    Article
  19. 619

    Novel insights of disulfidptosis-mediated immune microenvironment regulation in atherosclerosis based on bioinformatics analyses by Huanyi Zhao, Zheng Jin, Junlong Li, Junfeng Fang, Wei Wu, J. F. Fang

    Published 2024-11-01
    “…Bioinformatics techniques were used to evaluate differentially expressed genes (DEGs) associated with disulfidptosis-related AS. …”
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    Article
  20. 620

    RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients by Xiliang Zhang, Hanjie Guo, Xiaolong Li, Wei Tao, Xiaoqing Ma, Yuxing Zhang, Weidong Xiao

    Published 2024-10-01
    “…These genes were analyzed using univariate COX and machine learning algorithms to develop a prognostic scoring algorithm. …”
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    Article