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  1. 561

    Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes by Yan Lu, Rong Yuan, Rong Yuan, Qiqi Xin, Qiqi Xin, Keji Chen, Keji Chen, Weihong Cong, Weihong Cong

    Published 2025-06-01
    “…Identifying reliable biomarkers and understanding the interactions between immune senescence and AS may provide important therapeutic opportunities for AS.MethodsThe RNA sequencing and the single-cell RNA sequencing (scRNA-seq) dataset were downloaded from the Gene Expression Omnibus datasets, with all data derived from human tissues. Subsequently, differential expression analysis, weighted gene co-expression network analysis, accompanied by 3 machine learning algorithms, LASSO, SVM and RF, were performed to identify diagnostic genes. …”
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  2. 562

    How Small Can S-boxes Be? by Chenhao Jia, Tingting Cui, Qing Ling, Yan He, Kai Hu, Yu Sun, Meiqin Wang

    Published 2025-03-01
    “…Firstly, we evaluate the upper and lower bounds upon the minimum area of S-boxes, by proposing a Prim-like greedy algorithm and utilizing properties of balanced Boolean functions to construct bijective S-boxes. …”
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  3. 563

    Identification of biomarkers for Laryngeal squamous cell carcinoma through Mendelian randomization and integrated bioinformatics analysis by Pengjian Zhang, Weizhang Chen, Kai Chen, Yuanhang Ye, Weijun Wu

    Published 2025-07-01
    “…The differences in immune landscapes between high-risk and low-risk groups were assessed using the CIBERSORT algorithm, and drug sensitivity was analyzed using the “oncoPredict” package. …”
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  4. 564

    Identification of prognostic hub genes and functional role of BAIAP2L2 in prostate cancer progression: a transcriptomic and experimental study by Xiangyang Zhan, Xiangyang Zhan, Xiangyang Zhan, Xiangyang Zhan, Wenkai Wang, Jie Lian, Yichun Li, Jianyi Gu, Jianyi Gu, Jianyi Gu, Jianyi Gu, Dongdong Guo, Dongdong Guo, Dongdong Guo, Dongdong Guo, Dongliang Xu, Dongliang Xu, Dongliang Xu, Dongliang Xu, Guanqun Ju, Guanqun Ju, Guanqun Ju, Guanqun Ju

    Published 2025-04-01
    “…BackgroundProstate cancer (PCa) is a prevalent malignancy in men, and understanding its molecular mechanisms is crucial for identifying therapeutic targets.MethodsTranscriptomic data from prostate tumors and matched healthy tissues were obtained from The Cancer Genome Atlas (TCGA). Differential expression analysis using the DESeq2 algorithm identified differentially expressed genes (DEGs). …”
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  5. 565

    Development of a prognostic model for chemotherapy response and identification of TNFAIP2 as a target in colorectal cancer by Cheng Zhou, Chuan-Hai Xu, Min Xu, Xin-Kun Huang, Bin Zhu

    Published 2025-06-01
    “…The tumor microenvironment (TME) was assessed using the MCP-counter algorithm, and CRC cell experiments were performed to evaluate changes in drug sensitivity following oxaliplatin exposure. …”
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  6. 566

    Approximation-Aware Training for Efficient Neural Network Inference on MRAM Based CiM Architecture by Hemkant Nehete, Sandeep Soni, Tharun Kumar Reddy Bollu, Balasubramanian Raman, Brajesh Kumar Kaushik

    Published 2025-01-01
    “…This architecture includes a mapping algorithm that modulates inputs and map AFC to crossbar arrays directly, eliminating the need to predict approximated weights for evaluating output. …”
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  7. 567

    Combined detection of inflammatory proteins is beneficial for diagnosing the papillary thyroid carcinoma and nodular goiter by Yongqin Pan, Mingxi Xu, Tsz Hong Chong, Siping Xie, Kunsong Huang, Guanghao Wang, Yuhua Ma, Jinyi Li, Wah Yang

    Published 2024-09-01
    “…Receiver operating characteristic curve analysis was used to evaluate the diagnostic potential of differential expression of proteins via the area under the curve (AUC) analysis. …”
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  8. 568

    Bioinformatics Analysis of Oxidative Stress-Related Genes and Immune Infiltration Patterns in Vitiligo by Yang M, Wang H, Zhang R

    Published 2025-02-01
    “…Additionally, two machine learning algorithms were employed to identify hub genes, perform enrichment analyses, and evaluate their correlation with immune infiltration.Results: A total of 415 Oxidative Stress-DEGs were identified in vitiligo, including 317 up-regulated and 98 down-regulated genes. …”
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  9. 569

    Optimal Dimensional Synthesis of Ackermann and Watt-I Six-Bar Steering Mechanisms for Two-Axle Four-Wheeled Vehicles by Yaw-Hong Kang, Da-Chen Pang, Dong-Han Zheng

    Published 2025-07-01
    “…This study investigates the dimensional synthesis of steering mechanisms for front-wheel-drive, two-axle, four-wheeled vehicles using two metaheuristic optimization algorithms: Differential Evolution with golden ratio (DE-gr) and Improved Particle Swarm Optimization (IPSO). …”
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  10. 570

    XSShield: Defending Against Stored XSS Attacks Using LLM-Based Semantic Understanding by Yuan Zhou, Enze Wang, Wantong Yang, Wenlin Ge, Siyi Yang, Yibo Zhang, Wei Qu, Wei Xie

    Published 2025-03-01
    “…Through a Prompt Optimizer based on gradient descent and UCB-R selection algorithms, and a Data Adaptor based on program dependence graphs, the framework achieves real-time and fine-grained code processing. …”
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  11. 571

    Use of artificial intelligence in the diagnosis, treatment and surveillance of patients with kidney cancer by E. Yu. Timofeeva, С. R. Azilgareeva, A. O. Morozov, M. S. Taratkin, D. V. Enikeev

    Published 2023-10-01
    “…AI finds its application in histopathological evaluation: the AI model reaches 100.0% sensitivity and 97.1% specificity in the differential diagnosis of normal tissue from RCC. …”
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  12. 572

    Diagnostic value of leukocytosis in patients presenting to the emergency department with abdominal pain: A retrospective observational study by Erkan Boğa

    Published 2025-07-01
    “…Background: Abdominal pain is one of the most common complaints in emergency departments (EDs) and poses diagnostic challenges due to its broad differential diagnosis. Leukocytosis is frequently used as a biomarker in clinical evaluation; however, its diagnostic value in predicting surgical conditions remains unclear. …”
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  13. 573

    Identifying influential spreaders based on improving communication transmission model and network structure by Shimeng Zhang, Zejun Sun, Guan Wang, Haifeng Hu, Feifei Wang, Xiaoyan Sun

    Published 2025-03-01
    “…Through extensive experimentation, we demonstrate that our algorithm outperforms representative methods proposed in recent years in terms of consistency with the SIR model, similarity of Top-N nodes, and node importance differentiation. …”
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  14. 574

    Real-time crop row detection using computer vision- application in agricultural robots by Md. Nazmuzzaman Khan, Adibuzzaman Rahi, Veera P. Rajendran, Mohammad Al Hasan, Sohel Anwar

    Published 2024-10-01
    “…Secondly, a clustering algorithm is used to differentiate between the crop and weed pixels. …”
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  15. 575

    Diagnostic performance of actigraphy in Alzheimer’s disease using a machine learning classifier – a cross-sectional memory clinic study by Mathias Holsey Gramkow, Andreas Brink-Kjær, Frederikke Kragh Clemmensen, Nikolai Sulkjær Sjælland, Gunhild Waldemar, Poul Jennum, Steen Gregers Hasselbalch, Kristian Steen Frederiksen

    Published 2025-05-01
    “…We derived movement patterns (walking, running, resting, etc.) from raw accelerometry data using a proprietary algorithm. By evaluating the movement patterns during day and nighttime, we calculated 510 activity-related features, including robustness and fragmentation of the circadian rhythm. …”
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  16. 576

    Spatiotemporal High-Resolution Cloud Mapping with a Ground-Based IR Scanner by Benjamin Brede, Boris Thies, Jörg Bendix, Uwe Feister

    Published 2017-01-01
    “…This study presents a retrieval algorithm that evaluates observations of a hemispherically scanning thermal infrared radiometer, the NubiScope, to produce georeferenced, spatially explicit cloud maps. …”
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  17. 577

    Numerical simulation of magnetically driven nanomaterial rotating flow configured by convective-radiative cone with chemical reaction by Cyrus Raza Mirza, Muhammad Salman Kausar, Muhammad Nasir, M. Waqas, Nurnadiah Zamri, Iskandar Shernazarov, S.U. Khan, Nidhal Ben Khedher

    Published 2025-03-01
    “…Relevant variables are introduced to transfigure partial differential mathematical expressions to mathematical ordinary ones. …”
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  18. 578

    Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia by Xiangmei Xu, Jiamin Zhang, Hongyun Xing, Liying Han, Xiaoming Li, Pengqiang Wu, Jirui Tang, Li Jing, Jie Luo, Jing Luo, Lin Liu

    Published 2024-04-01
    “…Immune infiltration analysis was performed using a single-sample gene set enrichment analysis algorithm to evaluate the differential infiltration levels of immune cell types between ITP patient and control. …”
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  19. 579

    Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning by Jiao Li, Yupei Liu, Zhiyi Sun, Suqi Zeng, Caisong Zheng

    Published 2025-06-01
    “…To identify potential diagnostic biomarkers, we applied the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine-Recursive Feature Elimination (SVM-RFE) model, and Random Forest (RF) algorithm, and constructed Receiver Operating Characteristic (ROC) curves to evaluate accuracy. …”
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  20. 580

    Use of a Method for Contour Analysis of Radiation Images of Malignant Breast Tumors on the Basis of Retrospective Material by M. K. Mikhailov, E. A. Romanycheva, V. V. Sevast’yanov, Ya. A. Furman

    Published 2019-11-01
    “…An algorithm was elaborated for identifying the outlines of space-occupying lesions on X-ray mammographic images. …”
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    Article