Impacts of genomic alterations on the efficacy of HER2-targeted antibody–drug conjugates in patients with metastatic breast cancer by Riqing Huang, Anqi Hu, Qixiang Rong, Ditian Shu, Meiting Chen, Wei Yang, Yue Zhang, Qiufan Zheng, Xin An, Cong Xue, Haifeng Li, Yanxia Shi

“…Methods This comprehensive real-world retrospective study collected clinical data from patients diagnosed with metastatic breast cancer and performed genomic profiling using targeted next-generation sequencing. …”
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The effect of the number of endometrial CD138+ cells on the pregnancy outcomes of infertile patients in the proliferative phase by Yuye Li, Yuye Li, Shuyi Yu, Shuyi Yu, Wenjuan Liu, Yawen Chen, Xiaobing Yang, Juanhua Wu, Mingjuan Xu, Guanying You, Ruochun Lian, Chunyu Huang, Chunyu Huang, Wanru Chen, Yong Zeng, Yong Zeng, Fenghua Liu, Lianghui Diao

“…A total of 664 infertile women who were not diagnosed with chronic endometritis (CE) and who had not received the respective antibiotic treatment were studied. …”
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Association of different insulin resistance surrogates with all-cause and cardiovascular mortality among the population with cardiometabolic multimorbidity by Hongqiang Zhang, Zhixin Tu, Sihua Liu, Jumei Wang, Jie Shi, Xingyu Li, Rongdongqing Shi, Minghui Chen, Tong Yue, Sihui Luo, Yu Ding, Xueying Zheng

“…Methods This study enrolled 1093 patients diagnosed with CMM. We developed five surrogate markers to assess IR levels: triglyceride-glucose (TyG) index, TyG-waist circumference (TyG-WC), TyG-waist height ratio (TyG-WHtR), homeostatic model assessment of insulin resistance (HOMA-IR), and metabolic score for insulin resistance (METS-IR). …”
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High-risk habitat radiomics model based on ultrasound images for predicting lateral neck lymph node metastasis in differentiated thyroid cancer by Han Liu, Chun‑Jie Hou, Min Wei, Ke‑Feng Lu, Ying Liu, Pei Du, Li‑Tao Sun, Jing‑Lan Tang

“…Methods A group of 214 patients diagnosed with differentiated thyroid carcinoma (DTC) between August 2021 and August 2023 were included, consisting of 107 patients with confirmed postoperative lateral lymph node metastasis (LLNM) and 107 patients without metastasis or lateral cervical lymph node involvement. …”
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Reticulocyte hemoglobin content: a new frontier in iron deficiency diagnostics for major surgical patients by Suma Choorapoikayil, Mischa J. Kotlyar, Lisa Kawohl, Paul P. Pratz, Denana Mehic, Peter Kranke, Florian Rumpf, Lea V. Blum, Jan A. Kloka, Kai Zacharowski, Vanessa Neef, Patrick Meybohm

“…Conclusion This study highlights the potential of Ret-He as a promising alternative marker for diagnosing ID in patients undergoing major surgery, particularly in cases of elevated ferritin levels or non-anemic patients. …”
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Left atrial strain predicts paroxysmal atrial fibrillation recurrence after catheter ablation: a 1-year study using three-dimensional speckle-tracking echocardiography by Rui Zhang, He Li, Yan Wang, Tianle Yu, Jiacheng Li, Yumeng Wu, Zhiwen Yu, Cuixing Liang, Dan Yu, Li Xue

“…Methods A total of 109 patients diagnosed with drug-refractory PAF and scheduled for RFCA were included in this study between September 2019 and June 2022. …”
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Environmental surveillance of SARS-CoV-2 for outbreak detection in hospital: A single centre prospective study by Hania Siddiqui, Alexandra M.A. Hicks, Aaron Hinz, Prachi Ray, Jennie Johnstone, Derek R. MacFadden, Jason A. Moggridge, Michael Fralick

“…During the study period there were 4 patients diagnosed with COVID-19 on the Medical Rehab Unit and none on the Transitional Care Unit. …”
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Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series by L Bertels, K Manning, A Redd, T du Toit, Z Barday, E Muller

“…Among 39 HIV‐positive‐to‐HIV‐positive transplant recipients, 11 cases of COVID‐19 were diagnosed from March 2020 to September 2022. Six patients (55%) required hospitalisation, of whom 3 were admitted to a high‐care unit or intensive care unit. …”
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Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral... by Shuai Yang, En Deng, Linxin Chen, Yanbin Pi, Anhong Wang, Linghui Dai, Hongjie Huang, Xiaoning Duan, Xin Fu, Jiying Zhang, Qinwei Guo, Weili Shi

“…Methods: Cylindrical osteochondral defects (8.0 mm in diameter and 5.0 mm in depth) were surgically created bilaterally at the center of the medial femoral condyles in 27 Guangxi Bama minipigs. …”
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Beyond identification of familial hypercholesterolemia: Improving downstream visits and treatments in a large health care system by Harin Lee, Tarun Kadaru, Ruth Schneider, Taylor Triana, Carol Tujardon, Colby Ayers, Mujeeb Basit, Zahid Ahmad, Amit Khera

“…Patients whose PCP was contacted were more likely to have adjustments made to their lipid lowering medication(s) (p = 0.016), be diagnosed with FH (p = 0.025), and have a follow-up visit (p = 0.033). …”
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Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma by Li’nan Qin, Xiaopeng Guo, Lu Gao, Zihao Wang, Chenzhe Feng, Kan Deng, Wei Lian, Bing Xing

“…Clinical data of 39 patients with growth hormone- (GH-) secreting pituitary adenomas and 29 patients with nonfunctioning pituitary adenomas who were newly diagnosed in neurosurgery from January 2016 to December 2018 were retrospectively analysed, including measurements of preoperative and postoperative BMD, serum GH glucose inhibition, random GH and IGF-1, and other anterior pituitary hormones. …”
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The association of energy or macronutrient intake in three meals with depression in adults with cardiovascular disease: the United States National Health and Nutrition Examination... by Hongquan Xie, Yueying Chen, Jijiao Tang, Yuteng Ma, Ying Liu, Xiyun Ren

“…Energy and macronutrient intake was measured by a 24-h dietary recall, and depression was diagnosed by the Patient Health Questionnaire (PHQ-9, score ≥ 10). …”
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Prevalence of Respiratory Syncytial Virus Infection in Hospitalized COPD Patients in Spain Between 2018–2022 by Rosa María Gómez-García, Javier De-Miguel-Díez, Ana López-de-Andrés, Valentín Hernández-Barrera, Ana Jimenez-Sierra, Natividad Cuadrado-Corrales, José J. Zamorano-León, David Carabantes-Alarcón, Andrés Bodas-Pinedo, Rodrigo Jiménez-García

“…We selected subjects aged ≥40 years diagnosed with COPD, admitted to the hospital from 1 January 2018 to 31 December 2022. …”
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FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

“…The reactive oxygen specie (ROS) levels were evaluated by MitoSOX Red and 2′,7′-Dchlorodihydrofluorescein diacetate (DCFH-DA) probe. Anc80-Fam134b shRNA was used to knockdown the expression of FAM134B in SGNs.ResultsWe first found the expression of FAM134B in the cytoplasm of SGNs, especially in the fourth postnatal day mice. …”
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La bibliothèque dans Buffy contre les vampires : grimoires et merveilles by Vanessa Bertho

“…Elle s’avère incontournable pour la progression dramatique de la diégèse et l’installation des systèmes de représentation mythologiques. …”
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Prediction Models of Severity in Acute Biliary Pancreatitis by Iulia Ratiu, Renata Bende, Camelia Nica, Oana Budii, Calin Burciu, Andreea Barbulescu, Tudor Moga, Bogdan Miutescu, Roxana Sirli, Mirela Danila, Alina Popescu, Felix Bende

“…<b>Results:</b> 108 subjects (mean age of 60.1 ± 18.6, 65.7% females) diagnosed with acute biliary pancreatitis were included. …”
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The Effect of Coronary Artery Disease on the Prognosis of Hypertrophic Cardiomyopathy: A Multi-Center Cohort Study by Guoqing Hou, Qian Liao, Huihui Ma, Yan Shu, Shengzhi Zeng, Yongmei Zhou, Liangjun Luo, Gang Zhao, Tao He, Mingjiang Liu, Jianhong Tao, Wei Hua, Xiaoping Li

“…Conclusions: In this study, it was observed that there was no statistically significant disparity in mortality rates between patients diagnosed with HCM who concurrently had CAD and those who did not exhibit CAD. …”
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TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate by Paula Rofes, Carmen Castillo-Manzano, Mireia Menéndez, Álex Teulé, Sílvia Iglesias, Elisabet Munté, Mireia Ramos-Muntada, Carolina Gómez, Eva Tornero, Esther Darder, Eva Montes, Laura Valle, Gabriel Capellá, Marta Pineda, Joan Brunet, Lidia Feliubadaló, Jesús del Valle, Conxi Lázaro

“…Methods TP53 was analyzed in 6161 suspected hereditary cancer non-related patients categorized into three subgroups: (1) 495 patients fulfilling any LFS/Chompret clinical criteria; (2) 2481 patients diagnosed with early-onset breast/colorectal cancer; (3) 3185 patients without clinical criteria suggestive of hTP53rc. …”
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High Ki67 expression, HER2 overexpression, and low progesterone receptor levels in high-grade DCIS: significant associations with clinical practice implications by Hossein Schandiz, Hossein Schandiz, Lorant Farkas, Lorant Farkas, Daehoon Park, Yan Liu, Yan Liu, Solveig N. Andersen, Torill Sauer, Jürgen Geisler, Jürgen Geisler

“…Additionally, we investigated the associations between Ki67 expression, PR levels, and human epidermal growth factor receptor 2 (HER2) in high-grade DCIS among various subtypes (Luminal (Lum) A, LumB HER2-, LumB HER2+, HER2-enriched, and triple-negative)).MethodsUsing histopathological specimens from 484 patients diagnosed with DCIS between 1996 and 2018, we implemented the 2013 St. …”
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Computational analysis of reproducibility and image quality of 2011 and 2017 models of Heidelberg Spectralis SD-OCT machines by Kyoung A Viola Lee, Corey Tesdahl, Keith Zimmerman, Kimberly Jun, Sabrina Khalil, Alexander Shahin, Abdullah Abou-Samra, Ramesh Ayyala, Radouil Tzekov

“…Methods and testing: TRT measurements were performed using the Posterior Pole Algorithm (PPA) and Early Treatment Diabetic Retinopathy Study (ETDRS) grid protocols. …”
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