Diversity and distribution of nitrifying bacteria play an important role in the nitrogen cycle in mangrove sediments by A. Mubaraq, M. Sembiring, E. Widiastuti, E. Fachrial, B. Utomo, M. Turjaman, F. Sidik, Y.I. Ulumuddin, V.B. Arifanti, E.S. Siregar, T. Kajita, S. Proches, M. Basyuni

Get full text

Risk factors for gastric cancer and related serological levels in Fujian, China: hospital-based case–control study by Lin Cai, Wen Wang, Ping Yuan, Lan Lin, Kuicheng Zheng, Sihan Wu, Liangxiang Huang, Bingshan Wu, Tiehui Chen, Xiaoqing Li

“…Objective To explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, PG I/II ratio, gastrin 17 (G-17) and Helicobacter pylori infection, and to investigate dietary and lifestyle risk factors for gastric cancer in Fujian Province, China.Design A hospital-based, 1:1 matched case–control study.Setting Patients with newly diagnosed gastric cancer were recruited from the Fujian Provincial Hospital and the No. 900 Hospital of the Joint Support Force of the Chinese People’s Liberation Army between July 2014 and December 2016.Participants A total of 180 pairs of patients with gastric cancer and control subjects were recruited in the study, including 134 (74.4%) male pairs and 46 (25.6%) female pairs.Investigation and analysis measures Serological indicators were tested with ELISA kits. …”
Get full text

Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Background Metformin (Met) is the first-line treatment for type 2 diabetes mellitus and plays an effective role in treating various diseases, such as cardiovascular disease, neurodegenerative disease, cancer, and aging. …”
Get full text

NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder by Bin Gong, Chenxu Xiao, Yu Feng, Yu Feng, Jing Shen

“…This dataset included both type 1 and type 2 BD cases diagnosed based on DSM-IV, ICD-9, or ICD-10 criteria through standardized assessments. …”
Get full text

Development and validation of a prediction model for coronary heart disease risk in depressed patients aged 20 years and older using machine learning algorithms by Yicheng Wang, Yicheng Wang, Yicheng Wang, Chuan-Yang Wu, Hui-Xian Fu, Jian-Cheng Zhang, Jian-Cheng Zhang, Jian-Cheng Zhang

“…We aim to develop a machine learning (ML) model that will analyze risk factors and forecast the probability of coronary heart disease in individuals suffering from depression.MethodsThis research employed data from the National Health and Nutrition Examination Survey (NHANES) from 2007–2018, which included 2,085 individuals who had previously been diagnosed with depression. The population was randomly divided into a training set and a validation set, with an 8:2 ratio. …”
Get full text

Development and Validation of a Cost-Effective Machine Learning Model for Screening Potential Rheumatoid Arthritis in Primary Healthcare Clinics by Wu W, Hu X, Yan L, Li Z, Li B, Chen X, Lin Z, Zeng H, Li C, Mo Y, Wu Y, Wang Q

“…Wenqi Wu,1,2,* Xiaohao Hu,1,2,* Linyang Yan,3,* Zhiyin Li,4 Bo Li,5 Xinpeng Chen,6 Zexun Lin,7 Huiqiong Zeng,8 Chun Li,9 Yingqian Mo,10 Yalin Wu,3 Qingwen Wang1,2 1Department of Rheumatology and Immunology, Peking University Shenzhen Hospital, Shenzhen, People’s Republic of China; 2Shenzhen Key Laboratory of Inflammatory and Immunology Diseases, Shenzhen, People’s Republic of China; 3Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, People’s Republic of China; 4Department of Information Systems, City University of Hong Kong, Hong Kong, People’s Republic of China; 5Department of Rheumatology and Immunology, People’s Hospital of Longhua District, Shenzhen, People’s Republic of China; 6Department of Rheumatology and Immunology, Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, People’s Republic of China; 7Shenzhen Nanshan Medical Group HQ Taohuayuan Community Health Service Center, Shenzhen, People’s Republic of China; 8Traditional Chinese Medicine Department of Rheumatism, Women & Children Health Institute, Shenzhen, People’s Republic of China; 9Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, People’s Republic of China; 10Department of Rheumatology and Immunology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yalin Wu; Qingwen Wang, Email yalinwu@jj.ac.kr; wangqingwen@pkuszh.comObjective: In primary healthcare, diagnosing rheumatoid arthritis (RA) is challenging due to a general lack of in-depth knowledge of RA by general practitioners (GPs) and the lack of effective tools, leading to high rates of missed diagnosis. …”
Get full text

Effects of colchicine adjuvant therapy on disease control, serum NALP3, sICAM-1, MMP-9 and MMP-13 in patients with coronary heart disease and acute gout attack by Bingxun Wang, Yongqing Liu, Wenya Han, Bing Li, Pang Jie, Wenwen Yang, Zengcai Ma, Zesheng Xu

“…Before and after treatment, cardiac function indicators (left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD), left ventricular posterior wall thickness (LVPWT)), vascular endothelial function indicators (sICAM-1, endothelin-1 (ET-1), and vascular endothelial growth factor (VEGF)), inflammatory factors (NALP3, MMP-9, MMP-13) levels, changes in immune cell populations (CD3+ lymphocytes, CD3+CD4+ lymphocytes, CD3+CD8+ lymphocytes ratio, and CD3+CD4+/CD3+CD8+ ratio) were compared, and the incidence of adverse reactions was recorded. …”
Get full text

Maternal exposure to ambient temperature and risk of preterm birth in Chengdu, China, from 2017 to 2020: a cohort study by Qiqi Huang, Xiong-Fei Pan, Shijiao Yan, Zhonghan Sun, Yuwei Lai, Yixiang Ye, Jiaying Yuan, Chuanzhu Lv, Rixing Wang, Xingyue Song

“…Results Among the 6850 pregnant women, 301 (4.4%) were diagnosed with PTB. Compared to mild temperature (10th to 90th percentile), exposure to extreme cold (< 10th percentile) temperature during the 4 weeks preceding delivery (RR = 2.45, 95% CI:1.11,5.40) and throughout pregnancy (RR = 3.85, 95% CI:1.56,9.53) increased the risk of PTB. …”
Get full text

Optimization of the Screw Conveyor Device Based on a GA-BP Neural Network by Qiang Guo, Yunpeng Zhuang, Houzhuo Xu, Wei Li, Haitao Li, Zhidong Wu

“…Specifically, when the outer diameter of the spiral for screw conveyance in the straw baler was <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mi mathvariant="normal">D</mi><mo>=</mo><mn>320</mn><mo> </mo><mi>mm</mi></mrow></mrow></semantics></math></inline-formula>, the pitch was <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mi mathvariant="normal">S</mi><mo>=</mo><mn>200</mn><mo> </mo><mi>mm</mi></mrow></mrow></semantics></math></inline-formula>, and the rotational speed of the pickup shaft was <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>n</mi><mo>=</mo><mn>138</mn><mo> </mo><mi>r</mi><mo>/</mo><mi>min</mi></mrow></semantics></math></inline-formula>, the straw baler could achieve the maximum conveying capacity and the minimum power consumption. …”
Get full text

Correlation between serum homocysteine level and clinicopathological factors of IgA nephropathy by Cai Xiao-fan, Huang Jie-bo, Xing Yue, Cai Xiu-feng, Li Xue-ling, Zhong Yi-fei

“…ObjectiveTo investigate the correlation between serum homocysteine （Hcy） and clinicopathologic factors of immunoglobulin A nephropathy （IgAN）.MethodsA total of 349 patients with IgAN diagnosed by renal biopsy in the Nephrology Department of Longhua Hospital， Shanghai University of Traditional Chinese Medicine from January 1， 2014 to October 31， 2023 were retrospectively analyzed. …”
Get full text

Hospital and physician-based mental healthcare during 12 months of opioid agonist treatment for opioid use disorder: Exploring costs and factors associated with acute care. by Tea Rosic, Glenda Babe, Myanca Rodrigues, Brittany B Dennis, Richard Perez, Claire de Oliveira, Andrew Worster, Lehana Thabane, Zainab Samaan

“…<h4>Conclusions</h4>Individuals receiving treatment for OUD receive care in EDs, inpatient units, and outpatient clinics for mental health conditions other than substance use-related diagnoses. Healthcare costs were considerably higher for those receiving acute care treatment for mental health conditions. …”
Get full text

Profil Pasien Pneumonia Komunitas di Bagian Anak RSUP DR. M. Djamil Padang Sumatera Barat by Osharinanda Monita, Finny Fitry Yani, Yuniar Lestari

“…During the study period, 178 patients were diagnosed as CAP, 55.6% found in boys, especially in the age group 2 - &lt;12 months 43.8% with the poor nutritional status 62% and 34.8% have incomplete immunization status. …”
Get full text

Evaluating small coronary stents with dual-source photon-counting computed tomography: effect of different scan modes on image quality and performance in a phantom by Thomas Stein, Constantin von zur Muhlen, Niklas Verloh, Till Schürmann, Tobias Krauss, Martin Soschynski, Dirk Westermann, Jana Taron, Elif Can, Christopher L. Schlett, Fabian Bamberg, Christopher Schuppert, Muhammad Taha Hagar

“…METHODS: Utilizing a phantom setup mimicking the average patient’s water-equivalent diameter, we examined six distinct coronary stents inflated in a silicon tube, with stent sizes ranging from 2.0 to 3.5 mm, applying four different CT acquisition modes of a dual-source PCD-CT scanner: “high-pitch,” “sequential,” “spiral” (each with collimation of 144 × 0.4 mm and full spectral information), and “ultra-high-resolution (UHR)” (collimation of 120 × 0.2 mm and no spectral information). …”
Get full text

hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation by Mengyuan Chang, Ruiqi Liu, Bingqian Chen, Jin Xu, Wei Wang, Yanan Ji, Zihui Gao, Boya Liu, Xinlei Yao, Hualin Sun, Feng Xu, Yuntian Shen

“…C2C12 myotube nutrition-deprivation and mice tail suspension models were established. Subsequently, the diameter of C2C12 myotubes, Soleus mass, cross-sectional area (CSA) of muscle fibers, and grip strength in mice were assessed to investigate the impact of hBMSC-EVs on muscle atrophy. …”
Get full text

Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy by SiQin Xiu, Li Tang, Chengjie Qin, Di Tian, Yuhong Chen, Lingling Gu, Liu Yang, Yuhao Sun, Xinghui Liu, Yonghong Lin, Yumei Wang

“…Results Women with longer IPIs (≥ 120 months) were more likely to be older (≥ 35 years) and had higher rates of gestational diabetes and hypertensive disorders of pregnancy (p < 0.05). …”
Get full text

Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation by S.H. Larekeng, M. Nursaputra, M.F. Mappiasse, S. Ishak, M. Basyuni, E. Sumarga, V.B. Arifanti, A.A. Aznawi, Y.I. Rahmila, M. Yulianti, R. Rahmania, A. Mubaraq, S.G. Salmo III, H. Ali, I. Yenny

“…Field surveys were conducted to determine the species composition of each mangrove stand and measure their diameter at breast height. The allometric formula was then used to calculate mangrove biomass, which was subsequently converted into carbon stock values. …”
Get full text

Application of molecular approach in combination with providing treatment and control measures for combating Babesia bovis and Babesia bigemina infections in small scale livestock... by Nutsuda Klinkaew, Pairpailin Jhaiaun, Giang Thi Nguyen, Ruttayaporn Ngasaman, Domechai Keawnoi, Niorn Rattanapob, Pipat Arunvipas, Meyanee Kanjanaphan, Nuttapon Manojai, Suwitcha Panchakhan, Julaluk Jaiboon, Piyavadee Numnual, Prattana Tong-in, Thongphanchang Khanthong, Paween Srirarai, Chutima Chantarakot, Pattarakitti Noenchat, Jaroonwit Napornram, Somtat Yangsuk, Tanakrit Cham-iam, Phuncharat Nilsuwan, Supicha Jindarut, Kanokrat Boonyok, Nipa Thammasonthijarern, Wissanuwat Chimnoi, Tawin Inpankaew, Burin Nimsuphan, Jumnongjit Phasuk, Ketsarin Kamyingkird

“…Babesia parasites are difficult to diagnose in the early stage of infections during low parasitemia and asymptomatic conditions led to the lack of treatment and control at the early stage of infection. …”
Get full text

Positive effects of optimal dietary protein content on the growth, reproductive performance and health of Procambarus clarkii broodstock farming in rice field by Hui Luo, Feng Qin, Yu Li, Chuanbo Xiao, Wenbo Sun, Fan Liu, Guangjun Lv, Hua Ye, Yuanfa He, Wenping He, Feng Xu, Yong Lin, Dapeng Wang, Honghao Jin

“…Significant improvements in reproductive index, fecundity, egg diameter and egg production were found by increasing the dietary protein level from 28 % to 37 % (P < 0.05), while no significant increase was observed when the protein level was further increased to 43 % (P > 0.05). …”
Get full text

Definitional differences in “outpatient” surgery can influence study outcomes related to total shoulder arthroplasty by Junho Song, MD, Jennifer Yu, BS, Avanish Yendluri, BS, William A. Ranson, MD, Nikan K. Namiri, MD, John J. Corvi, MD, David E. Kantrowitz, MD, Thomas Boucher, MD, Leesa M. Galatz, MD, Paul J. Cagle, MD, Bradford O. Parsons, MD, Robert L. Parisien, MD

“…Compared to SDD, HDO was associated with female sex, higher body mass index, functional dependence, diabetes, chronic obstructive pulmonary disease, congestive heart failure, hypertension, American Society of Anesthesiologists ≥3, longer operation time, and nonhome discharge. …”
Get full text

Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context by Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu

“…Methods: This population-based cohort study used Swedish and Danish registry data for over 5.1 M individuals born between 1958 and 1993/1996. Specialist-diagnosed psychotic MDD was defined using ICD-10 sub-codes of MDD, F32.2/F32.3. …”
Get full text