Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy st... by Fu Zhao, Fu Zhao, Xiaojing Jiang, Yumeng Li, Tianjiao Huang, Zhikai Xiahou, Wenyang Nie, Qian Li

“…BackgroundHigh-grade serous ovarian cancer (HGSOC), the predominant subtype of epithelial ovarian cancer, is frequently diagnosed at an advanced stage due to its nonspecific early symptoms. …”
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Prediction of Acute Kidney Injury for Critically Ill Cardiogenic Shock Patients with Machine Learning Algorithms by Zhang X, Xiong Y, Liu H, Liu Q, Chen S

“…Xiaofei Zhang,1,* Yonghong Xiong,2,* Huilan Liu,3 Qian Liu,4 Shubin Chen5 1Department of Gerontology, China Aerospace Science & Industry Corporation 731 hospital, Beijing, People’s Republic of China; 2Department of Cardiology, Beijing Feng Tai Hospital, Beijing, People’s Republic of China; 3Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, People’s Republic of China; 4Department of Cardiology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China; 5Department of Intensive Care Unit, China Aerospace Science & Industry Corporation 731 hospital, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Liu, Department of Cardiology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, No. 100 of Xianggang Road, Jiangan District, Wuhan, 430015, People’s Republic of China, Tel +86027-82433350, Email qian_liu1124@126.com Shubin Chen, Department of Intensive Care Unit, China Aerospace Science & Industry Corporation 731 hospital, No. 3 Zhen Gang Nan Li, Yun Gang Town, Feng Tai District, Beijing, 100074, People’s Republic of China, Tel +86010-68374065, Email 18610074016@163.comBackground: The aim of this study was to use five machine learning approaches and logistic regression to design and validate the acute kidney injury (AKI) prediction model for critically ill individuals with cardiogenic shock (CS).Methods: All patients who diagnosed with CS from the MIMIC-IV database, the eICU database, and Zhongnan hospital of Wuhan university were included in this study. …”
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Clinical Study of Repetitive Transcranial Magnetic Stimulation Combined with Social Rehabilitation Training on Children with Attention Deficit Hyperactivity Disorder by JING Xinli, ZHU Min, NIU Yujia

“…ObjectiveTo observe the effect of repetitive transcranial magnetic stimulation (rTMS) combined with social rehabilitation training on children with attention deficit hyperactivity disorder (ADHD).MethodsA total of 60 children diagnosed with ADHD in the Children's Hospital of Nanjing Medical University from March 2019 to June 2022 were randomly divided into control group and observation group, with 30 cases in each group. …”
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Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

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Intelligent fault diagnosis method for rolling bearings based on flexible residual neural network by Chuang CHEN, Xianfeng LI, Jiantao SHI, Dongdong YUE

“…In numerous real-world situations, diagnosing faults in rolling bearings presents significant challenges. …”
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PhantomAR: gamified mixed reality system for alleviating phantom limb pain in upper limb amputees—design, implementation, and clinical usability evaluation by Cosima Prahm, Korbinian Eckstein, Michael Bressler, Zhixing Wang, Xiaotong Li, Takashige Suzuki, Adrien Daigeler, Jonas Kolbenschlag, Hideaki Kuzuoka

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Evaluation of Inflammatory Markers and Clinical Outcomes in COVID-19 Patients with Concurrent <i>Clostridioides difficile</i> Infection: A Comparative Cohort Analysis by Flavia Ignuta, Adrian Vlad, Teodor Cerbulescu, Stana Loredana, Felix Bratosin, Ovidiu Rosca, Lavinia Stelea, Daciana Nistor

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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…All cows received a GnRH injection 27 ± 3 d after AI and, if diagnosed as nonpregnant, completed the 5-d CoSynch protocol and received TAI 35 ± 3 d after insemination. …”
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals by Matthew O. Goodman, Tariq Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M. Lane, Brian Spitzer, Matthew Maher, Joon Chung, Brian E. Cade, Shaun M. Purcell, Xiaofeng Zhu, Raymond Noordam, Andrew J. K. Phillips, Simon D. Kyle, Kai Spiegelhalder, Michael N. Weedon, Deborah A. Lawlor, Jerome I. Rotter, Kent D. Taylor, Carmen R. Isasi, Tamar Sofer, Hassan S. Dashti, Martin K. Rutter, Susan Redline, Richa Saxena, Heming Wang

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Integrated Effects of Water and Nitrogen Coupling on Eggplant Productivity, Fruit Quality, and Resource Use Efficiency in a Cold and Arid Environment by Jie Li, Hengjia Zhang, Chenli Zhou, Anguo Teng, Lian Lei, Yuchun Ba, Jiandong Yu, Fuqiang Li

“…In the W₂N₂ treatment, the transverse diameter of eggplants, as well as the contents of soluble protein, soluble sugar, soluble solids, and vitamin C, were all the highest. …”
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Importancia de la estandarización de los reportes del perfil lipídico en los laboratorios clínicos by Ángel García, Javier Arango, Javier Cabrera, Jaime Melo, Harold Miranda, Katherine Restrepo, Marlene I. Vélez, Jaime A. Rodríguez

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Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases by Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, Cristian Papara, David A. De Luca, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, Matthias Laudes, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Ralf J. Ludwig, Ralf J. Ludwig

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Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP by Yi Wang, Weiwei Qiu, Stace Kernodle, Carly Parker, Marc-Antonio Padilla, Jiaao Su, Abigail J. Tomlinson, Stephanie Oldham, Joss Field, Elise Bernard, David Hornigold, Christopher J. Rhodes, David P. Olson, Randy J. Seeley, Martin G. Myers, Jr

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Le temple polygonal de la rue Lecointre à Reims/Durocortorum by Sébastien Péchart, Frédéric Poupon

“…The temple assumed two configurations: the internal space of the cella increased from 29 to 49 m2 through a reduction in wall diameter, which also generated a change in shape for the internal space of the cella, going from circular to octagonal. …”
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Evaluation of CellerateRX Surgical Powder utility in reducing groin complications after femoral exposure by Vy C. Dang, BS, Eric K. Peden, MD, Trisha Roy, MD, PhD, Alan B. Lumsden, MD, Linda Le, MD, Charudatta S. Bavare, MD, Sohaib K. Mhaidi, MD, Maham Rahimi, MD, PhD

“…A two-tailed Fisher's exact test demonstrated no statistically significant association between the presence of complications and the treatment group (P = .49, α = 0.05); however, patients in the experimental cohort were found to be a higher risk group, having significantly higher prevalence of diabetes and surgeries using a prosthetic. Conclusions: Based on the results of this study, we cannot conclude that a packing application of CellerateRX Surgical Powder alters the risk of developing postoperative groin complications compared with standard wound care. …”
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Artificial intelligence-assisted clinical decision support for childhood asthma management: A randomized clinical trial. by Hee Yun Seol, Pragya Shrestha, Joy Fladager Muth, Chung-Il Wi, Sunghwan Sohn, Euijung Ryu, Miguel Park, Kathy Ihrke, Sungrim Moon, Katherine King, Philip Wheeler, Bijan Borah, James Moriarty, Jordan Rosedahl, Hongfang Liu, Deborah B McWilliams, Young J Juhn

“…Children (<18 years) diagnosed with asthma receiving care at the study site were enrolled along with their 42 primary care providers. …”
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Long-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir by Shana Yi, David Truong, Brian Conway

“…We hypothesized that the offer of ongoing multidisciplinary care (including addiction care) after SVR12 was achieved would reduce the likelihood of loss to follow up, HCV reinfection or death and consolidate the gains achieved by initial engagement in care to diagnose and treat HCV infection. Methods: The inception cohort for this analysis was the 108 individuals achieving a cure of HCV infection within the GRAND PLAN study. …”
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Evaluation of treatment for diffuse large B-cell lymphoma using plasma D-dimer levels by Ruonan Shao, Danchen Meng, Beibei Gao, Lu Zhang, Qingqi Meng, Yanqiu Hou, Zhangbiao Long, Jinsong Yan, Xiaofeng Shi

“…This study means to retrospectively evaluate the role of D-dimer in prediction of treatment efficacy in patients with DLBCL. 151 patients with newly diagnosed DLBCL were enrolled. Blood samples were taken from those patients during the initial visit to our hospital and again after two cycles of chemotherapy to measure D-dimer levels. …”
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Clinical manifestations of COVID-19 infection and its impact on the outcome in children and adolescents with benign and malignant hematological disease in Egypt: a single-center ex... by Fatma Soliman Elsayed Ebeid, Aya Mostafa, Sondos M. Magdy, Haidy Moahmed Abd El Kader, Amal Abdel Azim Lotfy, Nihal Hussien Aly

“…Aim As a preliminary step in developing a national registry for children and adolescents with hemato-oncological disease who were diagnosed with COVID-19 infection, in this study we aimed to determine (a) the frequency of COVID-19 infection in children with hematological disease, (b) the presenting clinical manifestations, and (c) the associated underlying disease outcome and its clinical determinants. …”
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A latent class assessment of healthcare access factors and disparities in breast cancer care timeliness. by Matthew R Dunn, Didong Li, Marc A Emerson, Caroline A Thompson, Hazel B Nichols, Sarah C Van Alsten, Mya L Roberson, Stephanie B Wheeler, Lisa A Carey, Terry Hyslop, Jennifer Elston Lafata, Melissa A Troester

“…<h4>Methods and findings</h4>The Carolina Breast Cancer Study (CBCS) Phase 3 is a population-based, case-only cohort (n = 2,998, 50% black) of patients with invasive breast cancer diagnoses (2008 to 2013). We used latent class analysis (LCA) to group participants based on patterns of factors within 3 separate domains: socioeconomic status ("SES"), "care barriers," and "care use." …”
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