Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic... by Yuanchen Lv, Zibo Hua, Xiaomei Lu

“…IntroductionThe risk of kidney fibrosis is significantly elevated in individuals with diabetes, chronic nephritis, trauma, and other underlying conditions. …”
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An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study by Guanghao Liu, Shixiang Zheng, Jun He, Zi-Mei Zhang, Ruoqiong Wu, Yingying Yu, Hao Fu, Li Han, Haibo Zhu, Yichang Xu, Huaguo Shao, Haidan Yan, Ting Chen, Xiaopei Shen

“…Among patients forewarned as high risk, similar pathophysiological phenotypes and high mortality were observed in both those subsequently diagnosed as having SS and those without such a diagnosis. …”
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Clinical benefits and risks of remote patient monitoring: an overview and assessment of methodological rigour of systematic reviews for selected patient groups by Constanze Wartenberg, Helen Elden, Malte Frerichs, Lennart L Jivegård, Kajsa Magnusson, Georgios Mourtzinis, Ola Nyström, Kajsa Quitz, Helen Sjöland, Therese Svanberg, Helena Vallo Hult

“…Patient-relevant clinical benefits are limited or impossible to evaluate for most diagnoses based on currently available scientific information. …”
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Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically ‘cold’ tumor models by Barry E. Kennedy, Erin B. Noftall, Cheryl Dean, Alexander Roth, Kate N. Clark, Darren Rowles, Kulbir Singh, Len Pagliaro, Carman A. Giacomantonio, Carman A. Giacomantonio, Carman A. Giacomantonio

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Urban-rural disparities in cervical cancer screening among Indian women between 30–49 years: a geospatial and decomposition analysis using a nationally representative survey by Priyanka Garg, Yuvaraj Krishnamoorthy, Pritam Halder, Sathish Rajaa, Madhur Verma, Ankita Kankaria, Anil Goel, Rakesh Kakkar

“…Higher odds of having screening were associated with older age (AOR 1.45, 95% CI: 1.03–1.28), higher education (1.32; 1.13–1.55), higher age of first intercourse (1.60; 1.43–1.79), married (1.25; 1.08–1.45) and diabetic (1.39; 1.17–1.65) women, and those from South India (6.76; 5.90–7.75). …”
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Analysis of Role of Haematological Parameters in Diagnosis of Grampositive and Gram-negative Urinary Tract Infection: A Case-control Study by Sudha Srinivasan, Ayeesha Sithika Thajudeen, Kundhavai Chandrasekaran, Vijayashree Raghavan, D Roshini

“…Controls were also excluded if they had diabetes or chronic kidney disease. Urine cultures on blood and MacConkey agar identified pathogens such as E. coli, Pseudomonas, Klebsiella, Enterobacter, Proteus and Citrobacter. …”
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Influence of preoperative variables on the 3-month functional outcomes of the Vivity extended depth-of-focus intraocular lens: a prospective case series by Giacomo Savini, Alice Galzignato, Catarina P. Coutinho, Jinhai Huang, Yue Wu, Piero Barboni, João Mendanha Dias, Filomena J. Ribeiro, Domenico Schiano-Lomoriello

“…Methods In a prospective, single-center, non-randomized study, axial length, keratometry, anterior chamber depth, scotopic and photopic pupil diameters, pupil decentration, corneal asphericity, corneal higher-order aberrations (HOAs), coma and spherical aberration were measured preoperatively. …”
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The mutational landscape of ARMC5 in Primary Bilateral Macronodular Adrenal Hyperplasia: an update by Lucas Bouys, Anna Vaczlavik, Isadora P. Cavalcante, Florian Violon, Anne Jouinot, Annabel Berthon, Patricia Vaduva, Stéphanie Espiard, Karine Perlemoine, Peter Kamenicky, Marie-Christine Vantyghem, Antoine Tabarin, Gérald Raverot, Cristina L. Ronchi, Ulrich Dischinger, Martin Reincke, Maria C. Fragoso, Constantine A. Stratakis, Albain Chansavang, Eric Pasmant, Bruno Ragazzon, Jérôme Bertherat, for the COMETE and ENSAT Networks

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Simulator training in focus assessed transthoracic echocardiography (FATE) for undergraduate medical students: results from the FateSim randomized controlled trial by Johannes Matthias Weimer, Franziska Marietta Sprengart, Thomas Vieth, Sebastian Göbel, Anna Dionysopoulou, Rebecca Krüger, Jan Beer, Andreas Michael Weimer, Holger Buggenhagen, Roman Kloeckner, Lukas Pillong, Johanna Helfrich, Elias Waezsada, Philipp Wand, Julia Weinmann-Menke

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D-mannose alleviates chronic periodontitis in rats by regulating the functions of neutrophils by Xue Li, Xueting Chen, Qingyu Zhu, Pengye Zhang, Shunxue Nan, Lei Lv, Shengcai Qi

“…It significantly impacts oral health and has been linked to systemic conditions like cardiovascular disease and diabetes. The critical role of neutrophils in the occurrence and development of chronic periodontitis has been paid increasing attention. …”
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Genetic and audiological determinants of hearing loss in high-risk neonates by Yanan Shi, Naiyao Zhang, Na Du, Tongxi Zheng, Ying Yu, Youjin Li

“…In the larger hearing screening cohort, 497 (3.34%) were genetically positive for deafness mutations, among whom 29 had the diagnostic hearing tests and 7 eventually diagnosed with hearing loss. Of the rest 468 neonates who didn’t have the diagnostic tests, 445 (95.09%) passed the hearing screening tests. …”
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Neuropsychiatric profile in tuberous sclerosis complex patients with epilepsy by Mahmoud Fawzi Osman, Mahmoud Fawzi Osman, Faisal Hadid, Tawfeg ben Omran, Tawfeg ben Omran, Tawfeg ben Omran, Munira Aden, Fatima Al-Maadid, Sondos Altaraqji, Khalid Mohamed, Ruba Benini, Ruba Benini

“…Understanding the relationship between epilepsy severity, TSC-associated neuropsychiatric disorders (TAND), and cognitive outcomes is crucial for optimizing patient care.MethodsA retrospective study was conducted at a pediatric tertiary care hospital in Qatar, involving 38 TSC patients (20 female, 18 male) aged 1–18 years, diagnosed between October 2018 and March 2020. Epilepsy severity was assessed using the Early Childhood Epilepsy Severity Scale (E-Chess), and TAND was evaluated using the TAND checklist. …”
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Alchornea cordifolia leaf-extract ameliorates bisphenol A-induced obesity in male Wistar rats by Abdulhakeem Rotimi Agboola, Ako Hogan Itam, Chinedum Martins Ekeleme, Eyuwa Ignatius Agwupuye, Zuwairatu Oyiza Ahmed, Godswill Peter Igiakong, Gideon Bassey Agbor, Asmau Niwoye Abubakar, Zainab Adamu, Esien David-Oku, Item Justin Atangwho

“…One plant that has found application for weight loss amongst the local population in Nigeria is Alchornea cordifolia which commonly grows in Africa and has been confirmed to possess numerous medicinal properties including anti-inflammatory, anti-diarrheal, hepaprotective, antiviral, and anti-diabetic effects. Objective To evaluate the obesity attenuation effect of Alchornea cordifolia ethanol extract (ACEE) and other associated macrovascular health risks in BPA-induced obesity rat model. …”
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Construction of water injection seepage model for coal body and microscopic dominant influence law by Enmao WANG, Gang WANG, Shuliang XIE, Hongzhao WEI, Jing FENG, Handan LIANG

“…Initially, we developed a percolation model, incorporating elements such as pore throats, equivalent pore diameter, effective porosity, capillary bundles, tortuosity, and flow paths. …”
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Evaluation of Common and Atypical Clinical Presentations of Tinea Faciei: A Cross-sectional Study from Barabanki, Uttar Pradesh, India by Suganita, Deepika Agarwal, Sonal Sachan, Vandana Yadav, Harshit Jaiswal, Divya Prajapati

“…The authors have described various common and atypical clinical morphologies and distributions of tinea faciei and recognising these atypical signs can help clinicians diagnose the condition early and initiate timely treatment. …”
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Venous thromboembolism incidence and risk factors associated with immune checkpoint inhibitors among patients with advanced non-small cell lung cancer by Chi Nguyen, Alok A Khorana, John Barron, Jennell Palaia, Lisa Rosenblatt, Radhika Pisupati, Ning Huang, Kerrin Gallagher, T Christopher Bond

“…Patients with VTE before initiation of systemic treatment were excluded. Newly diagnosed VTE events were identified via inpatient and outpatient diagnosis codes. …”
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Construction of a diagnostic model for chronic mountain sickness among young male migrants to high-altitude areas by ZHANG Quan, CHEN Jian, LIU Bao

“…Results‍　‍According to the inclusion and exclusion criteria， 308 out of 376 participants were finally subjected， and 17.53% of them were diagnosed with CMS. The major clinical symptoms of the CMS patients were dyspnea or palpitations （79.63%） and sleep disorders （85.19%）. …”
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Modeling regional aboveground carbon stock dynamics affected by land use and land cover changes by A.D. Malik, M.C.W. Arief, S. Withaningsih, P. Parikesit

“…Land use and land cover changes were assessed from remotely sensed imagery data recorded in 2009 and 2021 using the maximum likelihood classification method in the geographic information as a collection of layers and other elements in a map 10.6 package. Tree height and diameter were collected within the purposively distributed plots with a size of 30 × 30 square meters. …”
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Evaluation of primary HPV-based cervical screening among older women: Long-term follow-up of a randomized healthcare policy trial in Sweden. by Qingyun Yao, Jiangrong Wang, K Miriam Elfström, Björn Strander, Joakim Dillner, Karin Sundström

“…We used national registries to identify the subsequent cervical tests and all histopathological diagnoses including ICC before December 31, 2022. We calculated cumulative incidence, incidence rate (IR) and IR ratio (IRR) of ICC, by baseline test result. …”
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Exploring the clinical value of procalcitonin, c-reactive protein, white blood cell count, and neutrophil-to-lymphocyte ratio in the early diagnosis of bloodstream infections in ch... by Yadong Li, Mingjie Li, Chenye Lin, Wentao Tang, Qiuyu Tang, Feng Cheng

“…Combined use of serum PCT, CRP, WBC, and NLR testing can improve the diagnostic sensitivity of pediatric BSI, reducing the risk of missed diagnoses, thereby enhancing the early diagnostic value of pediatric BSI.…”
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