Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe... by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…Introduction The prognosis for epithelial ovarian cancer (EOC) is exceedingly poor, with patients diagnosed with stage III/IV tumours typically offered cytoreductive surgery in conjunction with chemotherapy as a standard treatment option. …”
Get full text

TG : HDL-C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance by Ahmad Kamil Nur Zati Iwani, Muhammad Yazid Jalaludin, Ruziana Mona Wan Mohd Zin, Md Zain Fuziah, Janet Yeow Hua Hong, Yahya Abqariyah, Abdul Halim Mokhtar, Wan Nazaimoon Wan Mohamud

“…This study aims to examine the clinical utility of triglyceride to high-density lipoprotein ratio (TG : HDL-C) in identifying cardiometabolic risk and insulin resistance (IR) among children with obesity, in comparison with MetS as defined by the International Diabetes Federation (IDF). Data of 232 children with obesity aged 10–16 years were obtained from our study, MyBFF@school study, conducted between January and December 2014. …”
Get full text

Influence of climate factors on the formation of radial increment of walnut wood by Leonid Osadсhuk, Volodymyr Mahuran, Liubov Kondratiuk

“…Conversely, precipitation did not significantly affect the formation of diameter growth in trees growing in natural forest conditions. …”
Get full text

Gluten-Free Diet Adherence Evaluation in Adults with Long-Standing Celiac Disease by Marek K. Kowalski, Danuta Domżał-Magrowska, Piotr Szcześniak, Magdalena Bulska, Daria Orszulak-Michalak, Ewa Małecka-Wojciesko

“…Methods: The study included 57 people diagnosed with celiac disease between 1980 and 2010. …”
Get full text

The use of the long peroneal muscle tendon as an autograft during the primary plastics of the anterior cruciate ligament: a systematic review by Aleksey P. Prizov, Anatoly M. Vostrikov, Dmitry V. Skvortsov, Fedor L. Lazko, Maxim F. Lazko, Evgeniy A. Belyak, Alexandra V. Krytaeva

“…From the articles found, the following parameters were extracted: the evaluation of the functional results using the Tegner–Lysholm scale and the questionnaire for subjective assessment of the status among the patients with various knee joint injuries — IKDC (International Knee Documentation Committee); the evaluation of the mean diameter of the autotransplant; the instability of the knee joint; as well as the possible complications; the evaluation of the functions in the ankle joint and the foot using the AOFAS (American Orthopaedic Foot and Ankle Society) and FADI (Foot and Ankle Disability Index) scales. …”
Get full text

High-sensitive cardiac troponin T and NT-proBNP are associated with the left ventricular apical thickness in apical hypertrophic cardiomyopathy by Meng Zhang, Wei Gao, Xiaotong Cui, Xueting Han, Yamei Xu, Jingmin Zhou, Junbo Ge

“…For echocardiography parameters, hs-cTNT abnormal patients have thicker interventricular septum (IVS) (11.6 ± 2.0 vs. 11.0 ± 1.7, P = 0.02), thicker left ventricular apical (LVA) (16.9 ± 3.0 vs. 14.9 ± 2.3, P < 0.001) and larger left atrium diameter (LAD) (45.9 ± 6.6 vs. 42.4 ± 5.1, P < 0.001). …”
Get full text

The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients by Zhen-Hao Yu, Gui-Xiang Tian, Yao-Dong Wang, Ting-Yan Liu, Peng Shi, Jia-Yun Ying, Wei-Ming Chen, Yu-Feng Zhou, Guo-Ping Lu, Cai-Yan Zhang

“…The study included pediatric patients diagnosed with septic shock, analyzing their demographic data, GM-CSF and adjunctive therapies, laboratory results, and clinical outcomes. …”
Get full text

Penyeimbangan Kelas SMOTE dan Seleksi Fitur Ensemble Filter pada Support Vector Machine untuk Klasifikasi Penyakit Liver by Muhammad Amir Nugraha, Muhammad Itqan Mazdadi, Andi Farmadi, Muliadi, Triando Hamonangan Saragih

“…Liver function test data from the laboratory can be used to diagnose liver disease. Classification of liver disease in patients needs to be done well because the results can help in the initial diagnosis of whether a patient has liver disease. …”
Get full text

Can Early Diagnosis of Varices, Regular Praziquantel, and Reduction of Hepatitis Coinfection Reduce Mortality among Patients Attended for Periportal Fibrosis in Northwestern Tanzan... by Daniel W. Gunda, Elizabeth F. Mtui, Semvua B. Kilonzo, Paulina M. Manyiri, David C. Majinge, Humphrey D. Mazigo

“…These patients are at high risk of mortality since most of them are diagnosed late with bleeding varices. At Bugando, Schistosoma-related varices contributed to 70% of patients admitted due to vomiting blood with a two months’ mortality of over 10%. …”
Get full text

Jinkui Shenqi Pill Combined with Pelvic Floor Biofeedback in Treatment of Postpartum Stress Urinary Incontinence with Kidney-yang Deficiency by Xueqin MIAO, Hongri WANG, Meiyun GAO, Caifeng GUO, Jifen HU, Kunmu ZHANG

“…Objective:To explore the effect and mechanism of Jinkui Shenqi pill combined with pelvic floor biofeedback in treating of postpartum stress urinary incontinence with kidney-yang deficiency.Methods:A total of 70 full-term natural labor patients diagnosed with kidney-yang deficiency stress urinary incontinence about 42 days postpartum were selected and divided into control group and treatment group by random number table, with 35 cases in each group. …”
Get full text

Clinical and molecular characteristics and long-term outcomes of pediatric intracranial meningiomas: a comprehensive analysis from a single neurosurgical center by Leihao Ren, Jiaojiao Deng, Hiroaki Wakimoto, Qing Xie, Ye Gong, Lingyang Hua

“…Result 40 females (54.1%) and 34 males (45.9%) patients, with the gender ratio of 1.18:1, were identified. 9 (12.2%) cases were clinically diagnosed as NF2-related Schwannomatosis (NF2-SWN), while 65 (87.8%) were sporadic. …”
Get full text

Consistency analysis of two US techniques for evaluating hepatic steatosis in patients with metabolic dysfunction-associated steatotic liver disease by Fei Chen, Jingjing An, Long Deng, Jing Wang, Ruiling He

“…Methods Patients with suspicion or previously diagnosed of metabolic dysfunction-associated steatotic liver disease (MASLD) who attended fatty liver consulting room from June 2023 to September 2023 were prospectively recruited. …”
Get full text

Risk Factors and Pharmacological Interventions Impacting Cerebrovascular Ischemic Events in Giant Cell Arteritis: A Narrative Review by Muhammad Osama Siddiqui, Mohammad Ali Syed, Ayaan Ahmed Qureshi, Mustafa Hussain Imam, Jatin Motwani, Verkha Kumari, Arooba Siddiqui, Noor Ul Ain, Mohammed Hammad Jaber

“…Conclusion GCA‐related CIE such as stroke can be very debilitating and deadly conditions, particularly when GCA is initially diagnosed. However, with early diagnosis and proper management of risk factors, GCA‐related CIE can be prevented and its severity can be reduced. …”
Get full text

Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China. by Peilin Zhao, Tieyong Dong, Hongbin Lu, Rui Zhu, Shanshan Zhao, Wuqian Tao, Li Li, Chunmei Liu, Shuwei Pu, Ling Mo, Huanhuan Wang

“…A higher proportion of patients with pneumonia (18.7% vs. 9.5%, p = 0.033) and a longer length of hospitalization (7 vs. 6 days, p = 0.007) were seen in laboratory confirmed cases than clinically diagnosed cases. Compared to patients in the second trimester, a higher miscarriage rate (64.5% vs. 15.0%, p < 0.001) was observed in the first trimester, and a lower fetal death/stillbirth rate (1.0% vs 18.7%, p < 0.001) and a higher prematurity rate (21.0% vs. 9.3%, p = 0.019) were observed in the third trimester. …”
Get full text

Prevalence, cessation, and geographical variation of smoking among middle-aged and elderly adults in China: A population-based study by Qingjia Zeng, Chongyang Zhang, Feiyu Su, Yanli Wan, Wen-jun Tu, Hongpu Hu

“…Additionally, the dose-response relationship indicated a more pronounced association between higher smoking pack-years and elevated health risks, including hypertension (aOR=1.30, 95% CI: 1.24-1.36), diabetes (aOR=1.26, 95% CI: 1.20-1.33), hyperlipidemia (aOR=1.22, 95% CI: 1.16-1.28), heart disease (aOR=1.40, 95% CI: 1.26-1.54), and stroke (aOR=1.23, 95% CI: 1.10-1.36). …”
Get full text

Mini-review: Utilization of Vibrio parahaemolyticus virulence coding genes for early detection of acute hepatopancreatic necrosis disease (AHPND) by Munti Yuhana, Usamah Afiff

“…Furthermore, the use of molecular markers for the diagnosis of AHPND disease in shrimp must be validated by determining aspects of sensitivity, detection specificity, repeatability consistency, and reproducibility   Keywords: virulence-encoding gene, Vibrio parahaemolyticus, AHPND, diagnose, molecular marker   ABSTRAK   Kemampuan melacak keberadaan patogen Vibrio parahaemolyticus, agen penyebab AHPND pada udang adalah salah satu kunci untuk mengendalikan penyakit menular ini. …”
Get full text

Clinical Value of Renal Function Markers Combined with Blood Lipid Levels during Late Pregnancy to Predict Preeclampsia: A Retrospective Case-Control Study by Jindi Zhang, Pei Wang, Jie Liu

“…Methods: This was a retrospective case-control study that selected 263 eligible patients in late pregnancy diagnosed with PE as the case group and 264 healthy parturients as the control group. …”
Get full text

EPIGENETICS TODAY AND TOMORROW by B. F. Vanyushin

“…Distortions in DNA methylation and other epigenetic signals cause premature aging, cancer, diabetes, asthma, and severe mental dysfunctions. Changes in the DNA methylation profile accompany carcinogenesis, being a reliable diagnostic marker of various cancer species even at early stages of tumor formation. …”
Get full text

Controlled Resistant Hypertension Following A Successful Renal Artery Stenting: A Rare Case Report in A Developing Country by Fatihatul Firdaus Munita, Badai Bhatara Tiksnadi, Januar Wibawa Martha, Margareta Ginanti Ratna

“…Case Illustration A 36-year-old female visited the cardiovascular polyclinic on a common control for her hypertension. She was diagnosed with hypertension two years, and she had several episodes of malignant hypertension. …”
Get full text

Transmantle pressure under the influence of free breathing: non-invasive quantification of the aqueduct pressure gradient in healthy adults by Pan Liu, Kimi Owashi, Heimiri Monnier, Serge Metanbou, Cyrille Capel, Olivier Balédent

“…Males had a longer aqueduct than females (17.9 ± 3.1 mm vs. 15 ± 2.5 mm, p < 0.01) and a larger average diameter (2.0 ± 0.2 mm vs. 1.8 ± 0.3 mm, p = 0.024), but there was no gender difference in resistance values (p = 0.25). …”
Get full text