Pharmacogenomics predictors of aromatic antiepileptic drugs-induced SCARs in the Iraqi patients by Ali Fadhel Ahmed, Dzul Azri Mohamed Noor, Majeed Arsheed Sabbah, Nur Fadhlina Musa, Nur Aizati Athirah Daud

“…Methodology: A total of 50 patients diagnosed with SCARs and 90 tolerant controls were recruited from Dr. …”
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Human Primary Monocytes as a Model for in vitro Immunotoxicity Testing: Evaluation of the Regulatory Properties of TiO2 Nanoparticles by Svadlakova T, Kolackova M, Kulich P, Kotoucek J, Rosecka M, Krejsek J, Fiala Z, Andrýs C

“…This study focuses on titanium dioxide (TiO2) as an example of relatively low cytotoxic nanoparticles with potential biomedical use and aims to evaluate their possible modulatory effects on the inflammasome-based response in human primary monocytes.Methods: Monocyte viability, phenotypic changes, and cytokine production were determined after exposure to TiO2 (diameter, 25 nm; P25) alone. In the case of the modulatory effects, we focused on NLRP3 activation. …”
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Detection of Cervical Cancer and High Grade Neoplastic Lesions by a Combination of Liquid‐Based Sampling Preparation and DNA Measurements Using Automated Image Cytometry by Xiao Rong Sun, Jian Wang, David Garner, Branko Palcic

“…Results: A total of 876 women were followed by colposcopy examination where biopsies were taken from the visible lesions or from suspicious areas and histopathology diagnosed 459 as normal or benign cases, 325 as CIN1, 36 as CIN2, 25 as CIN3/CIS, and 31 as invasive cancer. …”
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SURGICAL TREATMENT OF PATIENTS WITH RESECTABLE NON SMALL CELL LUNG CANCER by K. I. Kolbanov, A. Kh. Trakhtenberg, O. V. Pikin, V. A. Glushko, A. B. Ryabov

“…Postoperative complications were diagnosed in 22.2%. The case fatality rate - 3.0%.Results. …”
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Augmentation index as a predictor of right ventricular dysfunction in coronary artery disease: a cross-sectional study by Arash Rahimi, Babak Geraiely, Hamed Vahidi, Mohammadreza Eftekhari, Ramyar Rahimi Darehbagh, Somayeh Mohammadi, Golrokh Ghaffari, Meysam Khoshavi

“…In multivariable analyses, AIx remained an independent predictor of RV dysfunction (adjusted odds ratio 3.42, 95% confidence interval 1.56–7.51, P = 0.002) after adjusting for age, sex, hypertension, diabetes, dyslipidemia, smoking, left ventricular ejection fraction, and Gensini score. …”
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Impact of Handgrip Strength on Survival in Hemodialysis Patients by Kyungho Park, Seongyeop Jeong, Hyerim Park, Eu Jin Lee, Young Rok Ham, Ki Ryang Na, Dae Eun Choi

“…In the multivariate Cox proportional hazards analysis, which adjusted for age, diabetes mellitus (DM), hypertension (HTN), BMI, fat tissue index (FTI), LTI, serum albumin, C-reactive protein (CRP), and CONUT score, HGS remained a significant predictor of survival in female dialysis patients (HR 2.77, 95% CI 1.00–7.65, <i>p</i> = 0.049). …”
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<i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> Hot-Spot Mutations in Relation to Sidedness of Primary Colorectal Cancer: A Retrospective Cohort Study by Omer Abdelgadir, Yong-Fang Kuo, Anthony O. Okorodudu, M. Firoze Khan, Yu-Wei Cheng, Jianli Dong

“…<b>Methods:</b> We performed a retrospective cohort analysis of 722 patients diagnosed with primary CRC and tested for <i>KRAS</i>, <i>NRAS</i>, and <i>BRAF</i> hot-spot mutations at the University of Texas Medical Branch (UTMB) from January 2016 through July 2023. …”
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Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial by Jiawei Shang, Ziming Yuan, Zuoyan Zhang, Quanhong Zhou, Yan Zou, Wei Wang

“…The percentage of participants with diabetes was 30.6% (38/124). The corresponding hazard ratio of the primary outcome in the intermittently scanned CGM (isCGM) group when compared with the point-of-care testing (POCT) group was 0.18 (95% CI 0.04-0.79). …”
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Vitamin D binding protein genetic isoforms, serum vitamin D, and cancer risk in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. by Stephanie J Weinstein, Dominick Parisi, Alison M Mondul, Tracy M Layne, Jiaqi Huang, Rachael Z Stolzenberg-Solomon, Regina G Ziegler, Mark P Purdue, Wen-Yi Huang, Christian C Abnet, Neal D Freedman, Kai Yu, Demetrius Albanes

“…Separately, the GC-cancer risk association was examined using proportional hazards regression among 109,746 individuals with genetic data and 26,713 diagnosed with cancer. Specific vitamin D binding protein isoform subtypes were delineated and analyzed, including Gc1-1 subtypes (Gc1s-Gc1s, Gc1f-Gc1s, and Gc1f-Gc1f) and Gc2 subtypes (Gc1s-Gc2, Gc1f-Gc2, and Gc2-Gc2). …”
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A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China by Yanqiu Xiong, Shanshan Liang, Wenjiao Tang, Li Zhang, Yuhuan Zheng, Ling Pan, Ting Niu

“…Abstract Background Chromosomal 1q gains and amplifications (+1q21) are frequently observed in patients with newly diagnosed multiple myeloma (NDMM). However, the interpretation of the high‐risk (HR) prognostic implications stemming from 1q21 abnormalities remain challenging to implement effectively. …”
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Correlation between liver fibrosis in non-alcoholic fatty liver disease and insulin resistance indicators: a cross-sectional study from NHANES 2017–2020 by Bo Yang, Mingsu Gong, Xiaojie Zhu, Yang Luo, Ruiqiu Li, Hai Meng, Yuhan Wang

“…The developed nomogram, incorporating AST, TyG, TyG-BMI, and diabetes, showed an AUC of 0.809 (95% CI: 0.771-0.847), indicating good predictive performance for LF in NAFLD patients.ConclusionsThis study confirms that a significant association between various IR and LF in NAFLD patients, and the developed nomogram provides a practical tool for early risk assessment. …”
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The Effect of Intravenous Metoclopramide on Pain, Nausea, Discomfort, and Ease of Insertion of Nasogastric Tube in Emergency Department: A Double-blind Randomized Clinical Trial by Seyed Mohammad Hosseininejad, Farzad Bozorgi, Asieh Khodami, Hamed Aminiahidashti, Mohammad Hajizade Juybari

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Gut Microbiome and Metabolite Characteristics Associated With Different Clinical Stages in Non-Small Cell Lung Cancer Patients by Liu F, Lu X, Tang M, Chen Y, Zheng X

“…The current study seeks to explore the distinctive gut flora and metabolite profiles of NSCLC patients across varying TNM stages.Methods: The research team gathered stool samples from 52 patients diagnosed with non-small cell lung cancer (NSCLC) and 29 healthy individuals. …”
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Effects of irrigation and organic fertilizer on pumpkin yield, quality, and water-fertilizer use efficiency in arid northwest China by Meng Yin, Jinxia Zhang, Liangliang Du, Lin Ding, Tao Zhong, Pengliang Tian, Runheng Yang

“…Irrigation quota and organic fertilizer application had a highly significant impact on pumpkin vine length and stem diameter (P &lt; 0.01), with a significant interaction between the two factors (P &lt; 0.05). …”
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Evaluation and Management of Patients with Hematoma After Gynecologic and Obstetric Surgery by Bekir Kahveci, Mehmet Obut, Serhat Ege, Mete Sucu, Nurullah Peker, Osman Uzundere, Gaye Kahveci, Mehmet Sukru Budak

“…Hematomas occurring after endoscopic surgery and episiotomy were not included. The diagnosed cases were divided into three groups as wound hematoma, rectus sheath hematoma and intra-abdominal hematoma (intraperitoneal and retroperitoneal). …”
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تأثیر تمرین هوازی تداومی و تناوبی بر سطوح سرمی گالکتین 3 و مقاومت به انسولین در رت‌های صحرایی نژاد ویستار مبتلا به دیابت بارداری... by احمد اربابی, مهدی مقرنسی, حامد فنایی, جواد نخزری خداخیر

“…مقاله پژوهشی مقدمه: دیابت بارداری (Gestational diabetes mellitus) GDM، یکی از شایع‌ترین بیماری‌های متابولیک در زنان باردار است. …”
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Facteurs associés aux spondyloarthrites axiales difficiles à traiter : résultats d’une étude rétrospective mono centrique sur 134 patients. by G Ndaie, P Lebughe, M Nzita, M Muamba, K Lobukulu, J Kanku, F Kemiche, M Chammakhi, S Rezki, C Mulumba, M Jenny, KJJ Malemba

“…Il n’y avait pas de différence quant à l’âge moyen des patients, aux comorbidités comme l’HTA et le diabète sucré et l’ancienneté de l’AxSpA. Conclusion : D2T AxSpA a concerné 35% des patients de notre étude, elle a été associée à l’inflammation biologique, à la présence d’enthésites et à la fibromyalgie/dépression. …”
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Nissen-Sleeve procedure versus laparoscopic Roux-en-Y gastric bypass in patients with morbid obesity and gastro-oesophageal reflux disease: protocol for a non-inferiority randomise... by Jan A Apers, Martin Dunkelgrun, Ivonne Leeuwenburgh, Judith W H 't Hart, Bo J Noordman, Laser U Biter

“…Exclusion criteria are achalasia, neoplastic abnormalities diagnosed during endoscopy, super obesity (body mass index ≥50 kg/m2), Crohn’s disease and medical history of major abdominal surgery. …”
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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…None of the participants were diagnosed with kidney disease. There was a high prevalence of asymptomatic UTIs among SCA patients at UTH, which, when coupled with the marked leukocytosis and anaemia, may negatively impact the clinical outcome of the patients. …”
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An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with... by Xiaodan Zheng, Yuanyuan Zheng, Yanlin Zhang, Jianlan Xie, Xiaojing Teng, Kuo Bi, Lan Sun, Xiaowen Huang, Mulan Jin, Xiaoge Zhou

“…Methods We present a retrospective study comparing 7 cases of adult EBV+ T-LPD and 16 cases of AITL with multiple EBV infections diagnosed at our institution from 2017 to 2022. Differences in immunophenotype, type of EBV-infected cells, clonality and gene mutations between the two groups of cases were compared by immunohistochemical staining, double-label staining, TCR gene rearrangement and next-generation sequencing analysis. …”
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