Corneal protective effects of a new ophthalmic formulation based on vitamin B12 and sodium hyaluronate by Francesca Lazzara, Federica Conti, Grazia Maugeri, Velia D’Agata, Velia D’Agata, Ludovica Sotera, Claudio Bucolo, Claudio Bucolo

“…Cell viability, cytotoxicity, ROS production, and mRNA expression of pro-inflammatory cytokines (TNF-α and IL-1β) were assessed by MTT, LDH, 2′,7′–dichlorofluorescein diacetate (DCFDA) assays and Real-time PCR, respectively. …”
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Fetal Growth Trajectories and Their Association with Maternal, Cord Blood, and 5-year Child Adipokines by H. C. Bartels, A. A. Geraghty, E. C. O’Brien, A. Kranidi, J. Mehegan, C. Yelverton, C. M. McDonnell, F. M. McAuliffe

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Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd by Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Mohammed Mostafa Al Quadir, Mst Rubaiat Nazneen Akhand, Mohammad Mehedi Hasan Khan

“…After 24 hours of incubation, tea and agarwood leaf extracts showed an 11–15 mm zone of inhibition against pathogenic A. caviae, while only BT-8 showed 7 mm (disc diameter 6 mm) against probiotic L. macroides. However, compared to leaf extracts, gentamicin showed a 27 mm zone of inhibition against both L. macroides strain SRU-001 and A. caviae strain YPLS-62 bacteria. …”
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Heterogeneity of DNA Distribution in Diploid Cells: A New Predicitive Discriminant Factor for Solid Tumour Behaviour by Jacques Assailly, Arnaud Desgrippes, Brigitte Loridon‐Rosa, Dominique Piron, Roger Dachez, Daniel Beurton

“…Spatial nuclear DNA heterogeneity distribution of Feulgen‐stained DNA diploid cells was studied by image cytometry in voided urine of 119 patients without bladder tumour (n=20) and with initial (n=23) or previous (n=76) diagnosed bladder tumour. For each patient, repetitive DNA measurements were performed during 1–4 years of follow up. …”
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The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology by Krista S. P. Clarke, Caroline C. Kingdon, Michael Pycraft Hughes, Eliana Mattos Lacerda, Rebecca Lewis, Emily J. Kruchek, Robert A. Dorey, Fatima H. Labeed

“…Clinicians thus eliminate differential diagnoses, and rely on subjective, unspecific, and disputed clinical diagnostic criteria—a process that often takes years with patients being misdiagnosed and receiving inappropriate and sometimes detrimental care. …”
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Exhaustion of CD8pos central memory regulatory T cell differentiation is involved in renal allograft rejection by Florian Kälble, Jonas Leonhard, Jonas Leonhard, Martin Zeier, Oliver Zivanovic, Matthias Schaier, Andrea Steinborn

“…The pathogenesis of graft deterioration in case of rejection involves the exhaustive differentiation of both CD8pos T cell subsets, but the causal mechanisms have not yet been identified.MethodsIn this study, we separately investigated the differentiation of CD8posTregs/Tresps in 134 stable KTR with no evidence of renal graft rejection, in 41 KTR diagnosed with biopsy-confirmed rejection at enrolment and in 5 patients who were unremarkable at enrolment, but developed rejection within three years of enrolment. …”
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Characteristics of Fly Ash from Coal Water Slurry Circulating Fluidized Bed Combustion by ZHANG Daixin, ZHANG Guoqing, LIU Haijun, HUANG Yongbo, DU Shanzhou, FAN Baoguo, HUANG Zhong

“…[Methods] The effects of feed mode, operating oxygen content, bed temperature, and primary air rate on unburned combustible in fly ash were studied by using a 3 MW circulating fluidized bed combustion test facility, the composition and micro-morphology of fly ash with different particle sizes were analyzed by using specific surface area and pore diameter analysis apparatus, scanning electron microscope, X-ray fluorescence spetrometer, and X-ray diffractometer (XRD). …”
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Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma by Selvam Thavaraj, Max Robinson, Shubham Dayal, Claire Bowen

“…Abstract Background Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cause of cancer death globally, with newly diagnosed oropharyngeal squamous cell carcinoma (OPSCC) cases rising to 54,000 in the US alone in the year 2022. …”
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Investigation of deflections and natural vibration frequencies of circular isotropic plates of variable thickness according to the law of square parabola with thickening to the sup... by A. V. Turkov, S. I. Poleshko

“…Based on the theoretical data obtained, it is possible to diagnose defects (change in the design scheme, destruction, reduction in the thickness of the plate as a result of corrosion, etc.) based on the results of comparison and analysis of theoretical and experimentally measured natural vibration frequencies and (or) maximum deflections in the center of the plate.Materials and methods. …”
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The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approach by Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang

“…Therefore, we employed unsupervised learning to translate five domains of eRDoC scores derived from electronic medical records (EMR) of patients diagnosed with Major Depressive Disorder (MDD), Schizophrenia (SCZ), and Bipolar Disorder (BD) at West China Hospital between 2008 and 2021. …”
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CT-based skeletal muscle loss predicts long term prognosis in patients with distal cholangiocarcinoma undergone pancreaticoduodenectomy by Guangzhen Qu, Shao-Cheng Lyu, Yong Zhang, Kun Gao, Chuanguo Zhou

“…Of the 112 patients with distal cholangiocarcinoma, 55 (49%) were diagnosed with low SMI preoperatively. The best cut-off values of SML were − 4.01% and − 5.99% for OS and RFS. …”
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Innovative Deep Learning Architecture for the Classification of Lung and Colon Cancer From Histopathology Images by Menatalla M. R. Said, Md. Sakib Bin Islam, Md. Shaheenur Islam Sumon, Semir Vranic, Rafif Mahmood Al Saady, Abdulrahman Alqahtani, Muhammad E. H. Chowdhury, Shona Pedersen

“…In general, the research emphasizes the efficacy of DL methods in successfully diagnosing cancer from histopathological pictures. It therefore indicates that DL has the potential to greatly improve medical diagnostic techniques.…”
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Association of e-cigarette and cigarette use with self-reported chronic obstructive pulmonary disease (COPD): a multivariable analysis of a large United States data set by Alicia J. Burns, Alexander W. Steinberg, James D. Sargent, Jenny E. Ozga, Zhiqun Tang, Cassandra A. Stanton, Laura M. Paulin

“…Methods Data from the 2020 National Health Interview Survey were used to estimate the association between each of 9 exposure categories based on cigarette use (never, former, current) and e-cigarette use (never, former, current), with respondent-reported physician-diagnosed COPD prevalence in individuals 40 years and older (N = 22,997). …”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease by Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas, Jose De la Hoz-Valle

“…It included one outpatient at the gastroenterology service in a fourth-level hospital, diagnosed with nonerosive reflux disease (NERD). Yet, his symptoms were heartburn and reflux, and his endoscopic results were normal esophageal mucosa, without hiatal hernia, though pathological pH values. …”
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Exercise medicine as adjunct therapy during RADIation for CAncer of the prostaTE to improve treatment efficacy – protocol for the ERADICATE study: a phase II randomised controlled... by Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão

“…Methods The ERADICATE study is a two-arm, parallel group, phase II randomised controlled trial. Fifty patients diagnosed with prostate cancer will be randomised (1:1) to either an exercise intervention group (EBRT + exercise) or a usual care control group (EBRT only) for the duration of treatment (i.e., 2 to 8 weeks of EBRT). …”
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A novel marker to determine arrhytmia risk in elite cyclists: T peak T end by Bulent Isık, Z. İsik Solak Gormus, Huseyin Aslan, Abdullah Iclı, Galip Bilen Kurklu, Ozgur Cıftcı, Turhan Togan

“…If the hypertrophic cardiomyopathy is not diagnosed and treated, it can lead to sudden deaths in athletes. …”
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Intelligent measurement of adolescent idiopathic scoliosis x-ray coronal imaging parameters based on VB-Net neural network: a retrospective analysis of 2092 cases by Jinlong Liu, Haoran Zhang, Pei Dong, Danyang Su, Zhen Bai, Yuanbo Ma, Qiuju Miao, Shenyu Yang, Shuaikun Wang, Xiaopeng Yang

“…Methods Retrospective analysis of 3192 patients aged 8–18 years who had a full-length orthopantomogram of the spine and were diagnosed with AIS at the First Affiliated Hospital of Zhengzhou University from January 2019 to March 2024. …”
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Patients with Age-related Macular Degeneration Have Increased Susceptibility to Valvular Heart Disease by Natan Lishinsky-Fischer, Itay Chowers, MD, PhD, Yahel Shwartz, MSc, Jaime Levy, MD

“…Main Outcome Measures: Heart valve-related diagnoses and procedures performed in both patient groups. …”
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High Concentration of Glucose Increases Reactive Oxygen Species Generation and Apoptosis Induced by Endoplasmic Reticulum Stress Pathway in Rabbit Corneal Epithelial Cells by Jiajun Lu, Minjie Sheng, Panpan Yao, Chaochao Ran, Hao Liu, Li Chen, Rui Liu, Bing Li

“…These results might provide theoretical basis for the study of the diabetes-related dry eye.…”
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Medical treatment for dry eye in patients with keratoconus after corneal cross-linking by I.A. Bubnova, G.B. Egorova, V.V. Averich, T.S. Mitichkina

“…Keratoconus stage 1 was diagnosed in 4 eyes, keratoconus stage 2 in 12 eyes, and keratoconus stage 3 in 2 eyes. …”
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