Medication underuse in real-life practice: the impact of galcanezumab towards achieving very low frequency episodic migraine in a southeast Asian middle-income nation by Wanakorn Rattanawong, Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Auranee Trisataya, Sekh Thanprasertsuk, Alan Rapoport

“…Adults aged 18 years or more who were diagnosed with HFEM or CM were included in this trial and categorized into two groups: galcanezumab and oral migraine preventive medication (OMPM). …”
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Ursolic acid attenuates obesity-related metabolic dysfunction via modulation of peroxisome proliferator activated receptor-gamma in male Wistar rats fed with high-carbohydrate high... by Oluwatosin O. Omodara, Mohammed U. Kawu, Ibrahim G. Bako, Daniel H. Mhya, Theophilus T. Dawus

“…Abstract Background The risk factors of metabolic syndrome (MS) precedes the development of cardiovascular disease and type 2 diabetes and are largely triggered by high-carbohydrate high-fat diet (HCHFD) and sedentary lifestyle. …”
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Current status and factors influencing kinesiophobia in patients with meniscus injury: a cross-sectional study by Faqiang Tang, Pan Xu, Cai Jiang, Xiaohua Ke, Dunbing Huang, Yaling Dai, Zhonghua Lin, Shizhong Wang

“…Methods A cross-sectional study involving 123 patients diagnosed with meniscus injuries at Fujian Provincial Hospital was conducted. …”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

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Comparison of Accuracy in Expert Clinical Examination versus Magnetic Resonance Imaging and Arthroscopic Exam in Diagnosis of Meniscal Tear by Seyed Ali Hashemi, Mohammad Reza Ranjbar, Mohammad Tahami, Reza Shahriarirad, Amirhossein Erfani

“…Many clinical tests and diagnostic studies have been developed to increase the clinician’s ability to accurately diagnose disorders of the knee. Torn menisci or ligamentous structures within the knee cause significant pain and disability and thus require expeditious management. …”
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Estimation of Apolipoprotein A1, Haptoglobin and Alpha 2macroglobulin with some Biochemical Metabolic Markers in Nonalcoholic Fatty Liver Disease Iraqi Patients by hiba abid Al-hussein hassan, Dawood Salman Dawood, Raghad Jawad Hussein

“…The study found that obesity (70%) and dyslipidemia (50%) are more common in NAFLD patients than another metabolic disease such as hypertension (20%) and diabetes mellitus (type 1 and 2) (3% and 30%) respectively. …”
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Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts by Wisdom U. Ike, Okereke C. Stanley, Nosiri Ijeoma, Okamgba C. Okezie, Nwokocha W. Osita, Aguwanba Chinedu, Aaron C. Friday

“…The results from the anti-bacterial assay showed that Salicia nitida root extract inhibited the growth of Staphylococcus aureus and Escherichia coliwith inhibitory zone diameters range of 17.00 - 19.50 mm and 20.50 - 28.50 mm for the standard antibiotic agents. …”
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The Role of Mature Brain-Derived Neurotrophic Factor and Its Precursor in Predicting Early-Onset Insomnia in Stroke Patients Experiencing Early Neurological Deterioration by Shi G, Yu P, Wang Z, Xu M, Guo M, Wang X, Zhou R

“…Serum levels of mBDNF and proBDNF were quantified using enzyme-linked immunosorbent assays. EOI was diagnosed according to the International Classification of Sleep Disorders, Third Edition (ICSD-3). …”
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Use of Texture Analysis on Noncontrast MRI in Classification of Early Stage of Liver Fibrosis by Ru Zhao, Xi-Jun Gong, Ya-Qiong Ge, Hong Zhao, Long-Sheng Wang, Hong-Zhen Yu, Bin Liu

“…Patients clinically diagnosed with hepatitis B infection, who underwent liver biopsy and noncontrast MRI scans, were enrolled. …”
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Association of body mass index with clinicopathological features among patients with clear cell renal cell carcinoma treated with surgery: a retrospective study by Zhibin Fu, Yewei Bao, Kai Dong, Di Gu, Zheng Wang, Jiean Ding, Ziwei He, Xinxin Gan, Zhenjie Wu, Chenghua Yang, Linhui Wang

“…No significant association was found between the pathological tumor diameter and BMI among the normal-weight, overweight, and obese groups (normal-weight vs. overweight, p = 0.31; normal-weight vs. obese, p = 0.21). …”
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Impact of Radiation Therapy Techniques on Hippocampal Doses and Psychological Status in Patients With Nasopharyngeal Carcinoma by Gai X, Huang S, Zeng J, Chen J, Liu F, Li S, Lv W, Guo F, Cai C, Hong J, Su L

“…Xiujuan Gai,1– 3,* Shiqi Huang,1,2,* Jiang Zeng,1,2,4 Jun Chen,1,2,4 Feng Liu,1,2,4 Shan Li,1,2,4 Wenlong Lv,1,2,4 Feibao Guo,1,2,4 Chuanshu Cai,1,2,4 Jinsheng Hong,1,2,4 Li Su1,2,4 1Department of Radiotherapy, Cancer Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, People’s Republic of China; 2Department of Radiotherapy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical Universisty, Fuzhou, Fujian, 350212, People’s Republic of China; 3Department of Oncology, Laiyang Central Hospital of Yantai, Yantai, 265200, People’s Republic of China; 4Key Laboratory of Radiation Biology of Fujian Higher Education Institutions, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li Su; Jinsheng Hong, Department of Radiotherapy, Cancer Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, People’s Republic of China, Email lily2230@126.com; 13799375732@163.comPurpose: To investigate the impact of Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) on hippocampal radiation dosage and psychological status in patients newly diagnosed with nasopharyngeal carcinoma (NPC).Patients and Methods: A retrospective analysis was conducted on 269 NPC patients who received initial treatment between January 2013 and April 2022. …”
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Level of systemic inflammation markers and clinical course in patients with stable ischemic heart disease with and without coronary atherosclerosis by V.I. Tseluyko, T.V. Pylova

“…Based on angiography data, patients were divided into two groups: group I – 53 patients with IHD and non-obstructive coronary arteries (INOCA), group II – 52 patients diagnosed with stable IHD with more than 50 % stenosis. …”
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Application of Near-infrared reflectance spectroscopy in the diagnosis of varicocele in children and adolescents by V.A. Digtiar, D.G. Vernihora, Yu.V. Zavorotnya, A.P. Gladkiy, M.O. Kaminska

“…The research utilizing Near-infrared Reflectance Spectroscopy revealed a significant potential of this method for diagnosing and assessing the impact of varicocele on the microcirculation of testicular tissue in children. …”
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Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017–2021: a retrospective study by Andre A. N. Bovell, Thendo Ramaliba, Sekeena O. Goodwin, Joycelyn C. Phillip, Jabulani Ncayiyana, Themba G. Ginindza

“…Results Between 2017 and 2021, 391 cases of female breast (41.7%), cervical (10.2%), colorectal (20.2%) and prostate (27.9%) cancers were diagnosed. Overall mean age at presentation was 61.5 (± 12.9) years, ranging from 24 to 94 years, age-standardized incidence rate 65.2 (95% CI: 58.7–71.6) per 100,000 population. …”
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Use of a microvascular anastomotic coupler device for kidney transplantation in rats by Henrik Lauer, Jana Ritter, Patrick Nachtnebel, Kathrin Simmendinger, Emily Lerchbaumer, Vladyslav Kavaka, Dominik Steiner, Jonas Kolbenschlag, Adrien Daigeler, Johannes C. Heinzel

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Synergistic effect of mulch and nitrogen management on growth and essential oil yield of Salvia sclarea L. by Diksha Dhiman, Sakshi Vishvamitera, Sidharth Baghla, Sanatsujat Singh, Dinesh Kumar, Ashok Kumar, Ramesh Chauhan

“…Among N management practices, N2 outperformed for all the morpho-physiological and yield parameters studied except stem diameter and produced at par outcomes with N5 in case of flower spike per plant, LAI, chlorophyll a and b, flower spike yield, EO content and yield. …”
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Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes by Mengmeng Sang, Jia Ge, Juan Ge, Juan Ge, Gu Tang, Qiwen Wang, Jiarun Wu, Liming Mao, Liming Mao, Xiaoling Ding, Xiaorong Zhou

“…For validation, a clinical cohort of patients diagnosed with pancreatic adenocarcinoma was examined using multiplex immunohistochemistry.ResultsWe were able to differentiate between hot and cold tumors in various types of cancer (bladder urothelial carcinoma, pancreatic adenocarcinoma, and cervical squamous cell carcinoma) by analyzing the presence of CD8+ T cells, activated natural killer cells, and M2-type macrophages, as well as the cytolytic activity and T cell proliferation. …”
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Prolonged pain-to-balloon time still impairs midterm left ventricular function following STEMI by Dominik Felbel, Sabrina Fackler, Rachel Michalke, Michael Paukovitsch, Matthias Gröger, Mirjam Keßler, Nicoleta Nita, Yannick Teumer, Leonhard Schneider, Armin Imhof, Dominik Buckert, Wolfgang Rottbauer, Sinisa Markovic

“…Mean age was 63 ± 12 years, 75% were male, 14% had diabetes, 72% had arterial hypertension, and 56% had history of smoking. …”
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Gambaran Kadar Trombosit, Besar Limpa dan Kadar Albumin Serum pada Pasien Sirosis Hati dengan Varises Esofagus by Vella Paraditha, Saptino Miro, Eti Yerizel

“…</p><p><strong>Kata kunci:</strong> kadar trombosit, besar limpa, kadar albumin, derajat varises esofagus</p><p> </p><p><strong><em>Abstract</em></strong></p><p><em>Esophageal varices is a complication in liver cirrhosis which can be diagnosed by endoscopy. However, on certain conditions, endoscopy examination can not be performed. …”
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Dietary habits and weight change during the second wave of the COVID-19 pandemic among the Egyptian population by Samar Abd ElHafeez, Yasmine Amr Issa, Samar Tharwat, Ahmed Yahia Elmowafy, Karem Mohamed Salem, Noha Gaber Amin, Mohammed Kamal Nassar, Ramy Ghazy Mohamed

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