Editorial by Jörg Tremmel, Edward Page, Konrad Ott

“…How should this unique absorptive function be divided between members of different generations? …”
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Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition by Antonino Glaviano, Hannah Si-Hui Lau, Lukas M. Carter, E. Hui Clarissa Lee, Hiu Yan Lam, Elena Okina, Donavan Jia Jie Tan, Wency Tan, Hui Li Ang, Daniela Carbone, Michelle Yi-Hui Yee, Muthu K. Shanmugam, Xiao Zi Huang, Gautam Sethi, Tuan Zea Tan, Lina H. K. Lim, Ruby Yun-Ju Huang, Hendrik Ungefroren, Elisa Giovannetti, Dean G. Tang, Tullia C. Bruno, Peng Luo, Mads Hald Andersen, Bin-Zhi Qian, Jun Ishihara, Derek C. Radisky, Salem Elias, Saurabh Yadav, Minah Kim, Caroline Robert, Patrizia Diana, Kurt A. Schalper, Tao Shi, Taha Merghoub, Simone Krebs, Anjali P. Kusumbe, Matthew S. Davids, Jennifer R. Brown, Alan Prem Kumar

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Componentes y Dinámica Natural del Ambiente - Ciudad de Neuquén- by Olga Capua, Elsie Marcela Jurio

“…Abstract The city of Neuquen, capital of the province, is located on the valleys' soils product or Limay and Neuquén rivers and on the surface, slopes and foothills of the plateau, located north of the town center. Up to 70s decade urban region was surrounded by agricultural areas, with intensive irrigation infrastructure and limited by rivers and relief with a marked topographic steep slope dissected by a dense network of rills and gullies. …”
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Poverty Dynamics and the Fundamental Root Causes in Iran by Zahra Azari, Parviz Mohamadzadeh, Davoud Behboudi

“…The relationship between system variables is displayed using causal loops. Findings In recent decades, despite the fact that the debate on poverty and poverty alleviation strategies has been raising in the world, and in some countries, basic measures have been taken to reduce income poverty and multi-dimensional poverty have taken place, not only has the situation not improved in Iran, but the country is facing huge crises in this field. …”
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Osiąganie kompromisu potrzeb człowieka i przyrody by Karol Lewandowski

“…Only by considering and deciding about ecoengineering alternatives we can choose the more appropriate method of handling with the natural environment. …”
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How long does carbon stay in a near-pristine central Amazon forest? An empirical estimate with radiocarbon by I. Chanca, I. Chanca, I. Chanca, I. Levin, S. Trumbore, K. Macario, K. Macario, K. Macario, J. Lavric, J. Lavric, C. A. Quesada, A. Carioca de Araújo, C. Quaresma Dias Júnior, H. van Asperen, S. Hammer, C. A. Sierra

“…Our results suggest that newly fixed carbon in this terra firme tropical forest is respired within 1 to 2 decades, implying that only a fraction of assimilated C can act as a sink for decades or longer.…”
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Teaching Pronunciation through Community Outreach by Frédérique Grim

“…/ Abstract (Français) Le concept de compétence fait partie intégrante de l'élaboration des pratiques et des programmes d'études des enseignants de langue seconde et est devenu un objectif commun dans la formation professionnelle, les congrès, les articles de revues et les magazines. …”
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Time Interval for Diagnosis of Tuberculosis and Related Expenditure in Selected Health Centers in Addis Ababa, Ethiopia by Ezra Shimeles, Melaku Tilahun, Tsegaye Hailu, Fikre Enquselassie, Abraham Aseffa, Alemayehu Mekonnen, Getachew Wondimagegn

“…TB programs need to identify the underlying factors for delay and related expenditure for TB related services, in order to devise an effective strategy to reduce them. Therefore, the study aimed to assess the time interval between developing TB symptom until patients start anti-TB treatment and associated cost incurred by patients and families. …”
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The Effect of Combining mHealth and Health Professional–Led Intervention for Improving Health-Related Outcomes in Chronic Diseases: Systematic Review and Meta-Analysis by Masashi Kanai, Takahiro Miki, Toshiya Sakoda, Yuta Hagiwara

“…The comparison groups consisted of participants receiving either general care and follow-up or those using mHealth devices without any health care professional involvement. …”
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Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study by Kim Daniels, Sharona Vonck, Jolien Robijns, Kirsten Quadflieg, Jochen Bergs, Annemie Spooren, Dominique Hansen, Bruno Bonnechère

“…In addition, incorporating wearable device integration and predictive analytics could provide real-time health data, optimizing activity recommendations and health monitoring. …”
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Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

“…The BMSCs of rats were randomly divided into the tension MSC group with detrusor stimulation and the MSC group without detrusor stimulation, after which osteogenic differentiation of BMSCs was induced in both groups. …”
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Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…ProspectsThis study posits seven development directions for deep CBM production and in-situ coal conversion experiments: (1) Clear, direct observation techniques for micropores (< 2 nm) in deep coal seams with ultra-low porosity and permeability, full-scale pore size splicing technology for multiscale pore structure characterized by abundant micropores, a few mesopores, and many macropores, and assessment techniques for pore-fracture connectivity. (2) Isothermal adsorption test technologies for raw coals considering the effects of deep coal seam wettability, fracturing fluid invasion, and high total dissolved solids (TDS) under high-temperature, high-pressure in-situ conditions; (3) Sealed coring devices and in-situ pressure-retaining coring technologies featuring high pressure retaining success rates, heat preservation rates, and traceable gas volume. (4) Nanoscience-based assessment technologies for gas and water occurrence in micropores in deep coal seams under high-temperature and high-pressure multi-field coupling, and experimental technologies for desorption, diffusion, and seepage across nano-micro-millimeter scales. (5) Techniques for developing and testing multifunctional mechanical experiment equipment applicable to in-situ conditions of deep coal seams featuring high stress, low modulus of elasticity, and high Poisson's ratio. (6) Experimental techniques for the purpose of enhancing CBM recovery of deep coal seams, including reservoir stimulation (microwaves, laser, and electric heating), stimulation for permeability enhancement (electromagnetic pulses, pulsed ultrasonic waves, and controlled shockwaves), displacement via CO2 injection, and mechanical pulsation with supercritical CO2. (7) Experimental techniques for in-situ coal conversion and utilization, including pyrolysis, underground coal gasification (UCG), geothermal utilization, and CO2 geological storage. …”
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Critical Success Factor Proyek TI: Studi Kasus Mobile Government by Ikhsan Triadi Syaputra, Teguh Raharjo, Bob Hardian, Tiarma Simanungkalit

“…This application is a mobile government (mGovernment) application that was built so that employees of XYZ Supervisory Institution can receive assignments and information by mail anywhere and anytime via a smartphone device. This is done to support employees of the XYZ Supervisory Institution who have high mobility in carrying out their duties as auditors. …”
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Analisis dan Evaluasi Pengalaman Pengguna PaTik Bali dengan Metode User Experience Questionnaire (UEQ) by I Nyoman Saputra Wahyu Wijaya, Putu Praba Santika, Ida Bagus Ary Indra Iswara, I Nyoman Alit Arsana

“…On the Google Play Store, the number of devices installed is more than 89,000 mobile. In this study, we want to know the level of user comfort in terms of User Experience. …”
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Gender differences in efficiency of the telemedicine care of heart failure patients. The results from the TeleEduCare-HF study by Agata Bielecka-Dąbrowa, Dariusz Trzmielak, Agata Sakowicz, Kamil Janikowski, Maciej Banach

“…Men more often survived sudden cardiac arrest (7.8% vs. 1.2%; p = 0.004) and had implantable cardiac devices compared to women (16% vs. 3%; p = 0.001). …”
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Application of fuzzy logic in decision-making process for relocation of floating net cages in river fish farming by R. Pramana, B.Y. Suprapto, Z. Nawawi

“…The river was divided into three sections: the river coast, the middle section, and the other river coast. …”
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A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes by Mark J. Cziraky, Scott Abbott, Matt Nguyen, Kay Larholt, Elizabeth Apgar, Thomas Wasser, Poul Strange, Leon Shi, H. Courtenay Harrison, Beverly Everitt, Lynn Nowak

“…**Objective:** This prospective pragmatic clinical trial evaluated V-Go, a wearable insulin delivery device, compared with standard treatment optimization (STO) among insulin-treated patients with T2DM in a realworld, community-based practice setting. …”
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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…ABSTRACT: Targeted reproductive management (TRM), employing automated monitoring devices (AMD), is as an alternative to the blanket adoption of ovulation synchronization protocols (OvSP) for first postpartum AI and a means of reducing the use of OvSP for re-insemination of nonpregnant cows. …”
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IDENTIFIKASI PIGMEN KLOROFIL DAN CELAH ENERGI PADA DAUN CINCAU (CYCLEA BARBATA) SEBAGAI FOTOSENSITIZER ALAMI UNTUK APLIKASI DSSC by Ismail Saleh, Wa Ode Nirwana Sari Halidun

“…Moreover, it can transfer electrons, so it can be used as a natural photosensitizer on dye-sensitized solar cell (DSSC) device. Natural photosensitizer has several advantages, such as its lower cost, abundant quantities, eco-friendly, and easy to synthesize. …”
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Utilisation des Anti-Inflammatoires Non Stéroïdiens chez les personnes âgées en rhumatologie au CHR-Tsévié (Togo) by VES Koffi-Tessio, E Fianyo, ML Diallo, S Oniankitan, A Adjolou, KC Tagbor, KA Nouvedji, M Ngakui, A Tsowou, C Deghela, K Kakpovi, P Houzou, O Oniankitan, M Mijiyawa

“…Résultats : Deux cent quarante- trois des 882 patients (27,6%) examinés au cours de la période d’étude et âgés d’au moins ­60 ans avaient utilisé des AINS. …”
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