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Enhanced effects of slowly co-released TGF-β3 and BMP-2 from biomimetic calcium phosphate-coated silk fibroin scaffolds in the repair of osteochondral defects
Published 2024-07-01“…These findings indicate that the biomimetic calcium-phosphate coated silk fibroin scaffolds with slowly co-released TGF-β3 and BMP-2 effectively promote the repair of OC defects, hence facilitating the future clinical translation of controlled drug delivery in tissue engineering. …”
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The water-agro-food system: upscaling from the Seine river basin to the global scale
Published 2022-09-01“…Coupling the GRAFS approach (Generalized Representation of Agro-Food Systems) to the Riverstrahler model (a biogeochemical drainage network model), allowed to make the link between the different issues of food production, river water quality and nutrient delivery to the coastal zone, as well as to develop an indicator of the risk for coastal water eutrophication (ICEP) now being included as an indicator for the United Nation Sustainable Development Goal (SDG) 14.…”
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Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer
Published 2025-01-01“…Here, this work addresses these challenges through gene electrotransfer (GET) of “naked” polyanionic DNA/mRNA using a single needle form‐factor which supports “electro‐lens” based compression of the local electric field, and local control of tissue conductivity, enabling single capacitive discharge minimal charge gene delivery. …”
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The Application of Traditional Chinese Medicine-Derived Formulations in Cancer Immunotherapy: A Review
Published 2025-01-01“…It explores the mechanisms by which TCM augments immune responses, particularly focusing on how these formulations influence both innate and adaptive immunity. Various TCM herbs and compounds, their active ingredients, and their application in cancer prevention and treatment were analyzed through an integrated review of preclinical studies, clinical trials, and molecular mechanistic investigations.Results: TCM formulations contribute to cancer therapy by modulating the body’s internal environment to improve immune defense. …”
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In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection
Published 2025-03-01“…The mRNA treatment in monkeys produced 3N39v4 in sera, which inhibited the replication of the authentic viruses. …”
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An Overview of Hybrid DC–DC Converters: From Seeds to Leaves
Published 2024-01-01“…Then, we share our observations, design intuitions, and suggestions to help the researchers and engineers to pick up and design a new SCI hybrid dc–dc converter.…”
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FOREIGN PRACTICE OF ORGANIZATION OF CARGO TRANSPORTATION BY INLAND WATER TRANSPORT IN RIVERSIDE CITIES
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MODIFIED LAUTENBACH TECHNIQUE AND EXTERNAL FIXATION AS A TREATMENT FOR INFECTED NON-UNION OF THE SUBTROCHANTER FEMUR: A CASE REPORT
Published 2019-12-01“…No infection recurrence was found, and Haris Hip Score was 91 (excellent). Based on the result of this case, definite external fixation and modified Lautenbach technique in one stage surgery can be a viable option in treating infected non-union of subtrochanter femur.…”
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Towards a Stunting-Free Gunungsitoli City: Policy Evaluation and Challenges of the Economic Approach
Published 2025-02-01“…Based on the results of the research using evaluation indicators that believe in effectiveness, efficiency, adequacy, leveling, responsiveness, and accuracy, the implementation has not been optimal or running well based on several criteria, namely the budget from the APBD for policies and programs to accelerate stunting reduction is still limited, access to stunting sufferers is still constrained considering the demographic conditions of the region spread across various regions, the existence of complex socialization So that the delivery of information is not effective and the implementation time of policies and programs is not too much so that the implementation of policies does not run well and the short implementation time makes programs and policies not optimal in terms of their implementation and economic challenges in handling stunting are met with poverty and limited access to nutrition, dependence on external resources, and economic impacts do not last long This stunting results in a decrease in productivity labor force, the burden of regional health increased, and poverty arose. …”
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Enhancing drug discovery and patient care through advanced analytics with the power of NLP and machine learning in pharmaceutical data interpretation
Published 2025-04-01“…These results not only highlight the revolutionary capabilities of NLP and ML in harnessing data-driven insights for healthcare but also lay a robust groundwork for future advancements in personalized medicine and bespoke treatment pathways. …”
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Kombinasi Intent Classification dan Named Entity Recognition pada Data Berbahasa Indonesia dengan Metode Dual Intent and Entity Transformer
Published 2024-10-01“…Kombinasi hyperparameter yang telah diperoleh menghasilkan kapabilitas yang berbeda apabila terdapat perubahan dalam data yang digunakan, karena kapabilitas model DIET baik dalam melakukan klasifikasi intensi maupun NER sangat bergantung terhadap data. Abstract Customer service is a way to fulfill the wants and needs of customers accompanied by the accuracy of delivery according to company standards in order to meet customer expectations. …”
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Determinants of Facility-Based Childbirth in Indonesia
Published 2019-01-01“…This study showed that a high level of education (OR: 3.035, 95% CI: 2.310–3.987), high economic status (OR: 6.691, 95% CI: 5.768–7.761), urban residence (OR: 2.947, 95% CI: 2.730–3.181), working status (OR: 0.853, 95% CI: 0.793–0.918), involvement in decision-making (OR: 0.887, 95% CI: 0.804–0.910), and having more than four visits to antenatal care centers (OR: 1.917, 95% CI: 1.783–2.061) were significant determinants of delivery at healthcare facilities. …”
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The Interplay between Defensins and Microbiota in Crohn’s Disease
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study
Published 2025-01-01“…Background: Monthly intramuscular injections of benzathine penicillin G (BPG) remain the cornerstone of secondary prophylaxis for acute rheumatic fever and rheumatic heart disease (RHD). The barriers to successful delivery of BPG may be patient- or service-delivery-dependent. …”
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