First Autologous Cord Blood Therapy for Pediatric Ischemic Stroke and Cerebral Palsy Caused by Cephalic Molding during Birth: Individual Treatment with Mononuclear Cells by A. Jensen, E. Hamelmann

“…Here we report a rare case of neonatal arterial ischemic stroke and cerebral palsy caused by fetal traumatic molding and parietal depression of the head during delivery caused by functional cephalopelvic disproportion due to a “long pelvis.” …”
Get full text

Protocol for live imaging of axonal transport in iPSC-derived iNeurons by Dan Dou, Erika L.F. Holzbaur, C. Alexander Boecker

“…Summary: Studies of human induced pluripotent stem cell (iPSC)-derived neurons promise important insights into neurodegenerative diseases. Here, we present a protocol for live imaging of axonal transport in glutamatergic iPSC-derived neurons (iNeurons). …”
Get full text

Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature by Carlos Zagalo, Francesca Pierdomenico, José Cabeçadas, Pedro David Santos

“…Burkitt's lymphoma (BL) is an aggressive B-cell malignancy with very high proliferation rate, more common in males than females. …”
Get full text

Multimodality Imaging of Endothelial Progenitor Cells with a Novel Multifunctional Probe Featuring Positive Magnetic Resonance Contrast and Near-Infrared Fluorescence by Shenghong Ju, Yiru Qiu, Cong Li, Gao-Jun Teng, Yicheng Ni

“…Our preliminary data suggest that as a multimodal imaging contrast medium, Conjugate 1 offers a promising imaging probe for tracking the delivery and therapeutic response of EPCs in vivo.…”
Get full text

An Analytical Perspective on Determination of Free Base Nicotine in E-Liquids by Vinit V. Gholap, Rodrigo S. Heyder, Leon Kosmider, Matthew S. Halquist

“…In electronic cigarette users, nicotine delivery to lungs depends on various factors. One of the important factors is e-liquid nicotine concentration. …”
Get full text

Understanding the unique role of community-based para-professionals delivering early childhood development in low-resource contexts: a Delphi study by Emma Claire Pearson, Maxwell Peprah Opoku

“…Abstract Background Community-based para-professionals are trained or untrained professionals who assist in the delivery of health-related care in communities where they live. …”
Get full text

Persistent Suppression of Type 1 Diabetes by a Multicomponent Vaccine Containing a Cholera Toxin B Subunit-Autoantigen Fusion Protein and Complete Freund’s Adjuvant by Béla Dénes, István Fodor, William H. R. Langridge

“…Data presented here demonstrate multifunctional vaccination strategies that harness vaccinia virus mediated delivery of a gene encoding an immunoenhanced diabetes autoantigen in combination with complete Freund’s adjuvant (CFA) that can maintain safe and durable immunologic homeostasis in NOD mice. …”
Get full text

Energy Efficient Cluster Based Scheduling Scheme for Wireless Sensor Networks by E. Srie Vidhya Janani, P. Ganesh Kumar

“…In the first phase of our proposed scheme, cluster topology is discovered and cluster head is chosen based on remaining energy level. The cluster head monitors the network energy threshold value to identify the energy drain rate of all its cluster members. …”
Get full text

Principle of Limiting Factors-Driven Piecewise Population Growth Model I: Qualitative Exploration and Study Cases on Continuous-Time Dynamics by Héctor A. Echavarria-Heras, Cecilia Leal-Ramírez, Guillermo Gómez, Elia Montiel-Arzate

“…Possible phase configurations include regimes with multiple stable equilibria, sigmoidal growth, extinction, or stationarity. Here, we also outline that the associating discrete-time piecewise model composes the logistic map applied over a particular region of the phase configuration. …”
Get full text

Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering by Yuting Li, Hao Meng, Yuan Liu, Bruce P. Lee

“…Here, we review the recent advancement in developing fibrin-based biomaterials for the development of injectable tissue engineering scaffold and cell carriers.…”
Get full text

The consequence of day-to-day stochastic dose deviation from the planned dose in fractionated radiation therapy by Subhadip Paul, Prasun Kumar Roy

“…Our analysis shows that that the fixed dose delivery approximation under-estimates the biological effective dose, even if the average delivered dose per fraction is equal to the planned dose per fraction. …”
Get full text

A human skin-on-a-chip platform for microneedling-driven skin cancer treatment by Natan R. Barros, Raehui Kang, Jinjoo Kim, Menekse Ermis, Han-Jun Kim, Mehmet R. Dokmeci, Junmin Lee

“…However, challenges remain in creating models suitable for microneedling applications and monitoring, as well as developing skin cancer models for analysis and targeted therapy. Here, we developed a human skin/skin cancer-on-a-chip platform within a microfluidic device using bioprinting/bioengineering techniques. …”
Get full text

A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy by Ling Wang, Yuzhong Zhang, Shenglin Geng, Lan Ma, Yiran Wang, Dongxu Han, Guojuan Fan, Weifen Zhang, Weifen Zhang, Weifen Zhang, Yanna Lv, Jinlong Ma, Jinlong Ma, Jinlong Ma

Get full text

Indirect contacts between Danish pig farms – what are the frequencies and risk-reducing measures, and how can they be used in simulation models? by Mette Fertner, Beate Conrady, Anne Sax Røgind, Elisabeth Okholm Nielsen, Anette Boklund

“…Abstract Background Information on indirect contacts (e.g. contact with visitors and non-porcine species on farms, shared staff and equipment, contact with trucks) is often poorly recorded even though it constitutes a risk in terms of disease transmission. The aim of the present study was to quantify the number of indirect contacts and associated biosecurity measures in Danish pig herds. …”
Get full text

SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis by Carina Magdaleno, Daniel J. Tschumperlin, Narendiran Rajasekaran, Archana Varadaraj

“…We show that adenoviral delivery of the SOCS domain in the fibrotic phase of experimental lung fibrosis in mice, significantly reduces collagen accumulation in disease lungs. …”
Get full text

Microscopic Analysis of Severe Structural Rearrangements of the Plant Endoplasmic Reticulum and Golgi Caused by Overexpression of Poa semilatent virus Movement Protein by Andrey G. Solovyev, Joachim Schiemann, Sergey Y. Morozov

“…TGBp1 binds viral genomic RNAs to form ribonucleoprotein complexes representing the transport form of viral genome, while TGBp2 and TGBp3 are necessary for intracellular delivery of such complexes to plasmodesmata. Recently, it was revealed that overexpression of Potato virus X TGBp3 triggers the unfolded protein response mitigating the endoplasmic reticulum (ER) stress leading to cell death if this protein reaches high levels in the ER. …”
Get full text

Familial Blue Rubber Bleb Nevus Syndrome in Pregnancy with Spinal Epidural Involvement by Daigo Ochiai, Kei Miyakoshi, Kazumi Yakubo, Tatsuro Fukuiya, Yasunori Yoshimura

“…The patient presented with multiple VMs on her head, neck, floor of the mouth, trunk, leg, foot, and vulva and spinal epidural lesions. …”
Get full text

Bioreactance-Based Noninvasive Fluid Responsiveness and Cardiac Output Monitoring: A Pilot Study in Patients with Aneurysmal Subarachnoid Hemorrhage and Literature Review by Sanjeev Sivakumar, Christos Lazaridis

“…We, here, review a noninvasive monitoring technique based on thoracic bioreactance and focusing on continuous cardiac output and fluid responsiveness markers.…”
Get full text

Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

“…However, the mechanism underlying Stx delivery remains unclear. Here we pinpoint monocytes as the primary carriers responsible for transporting Stx2 to the renal region. …”
Get full text

Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…The hydrogen concentrations of blood samples collected from the left internal jugular vein 3 cm to the heart from the tip of the infusion line were 6.4 (30 min), 4.7 (60 min), 4.9 (90 min), and 5.3 (120 min) ppb <i>w</i>/<i>w</i>, respectively. …”
Get full text