Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2 by Charlotte Laurfelt Munch Rasmussen, Signe Frost Frederiksen, Christian Würtz Heegaard, Maj Schneider Thomsen, Eva Hede, Bartosz Laczek, Jakob Körbelin, Daniel Wüstner, Louiza Bohn Thomsen, Markus Schwaninger, Ole N. Jensen, Torben Moos, Annette Burkhart

“…Conclusion The data suggests cross-correcting gene therapy to the brain via delivery of NPC2 from BECs and neurons.…”
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Nanoemulsion: An Emerging Novel Technology for Improving the Bioavailability of Drugs by null Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Chanchal Rani, Renu Saharan, Suresh Kumar, null Geeta, Renu Sehrawat

“…The pharmaceutical sector has made considerable strides recently, emphasizing improving drug delivery methods to increase the bioavailability of various drugs. …”
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Dendrimer functionalized folate-targeted gold nanoparticles for luciferase gene silencing in vitro: A proof of principle study by Mbatha Londiwe Simphiwe, Maiyo Fiona Chepkoech, Singh Moganavelli

“…The need for target-specific siRNA delivery vehicles is crucial to successful gene silencing. …”
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Molecular Mechanisms Involved in Mesenchymal Stem Cell Migration to the Site of Acute Myocardial Infarction by Katarina Kollar, Matthew M. Cook, Kerry Atkinson, Gary Brooke

“…Current strategies for MSC delivery to heart involve intravenous, intraarterial, and intramuscular delivery. …”
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A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease by Qin Shen, Yongjie Jiang, Jing Chen, Xueling Wang, Jiao Zheng

“…The dry powder inhaler is a new form of drug delivery that is widely used as an alternative to traditional drug delivery methods, addressing the shortcomings of traditional drug delivery methods and obtaining better therapeutic results. …”
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ASSESSING THE SYNERGETIC EFFECT OF SELECTING THE OPTIMAL STRUCTURE OF A LOGISTICS CHAIN by Vitalii NAUMOV, Ihor TARAN, Zhumazhan ZHANBIROV, Batyrbek MUSSABAYEV, Zarina KONAKBAI

“…These stakeholders include freight owners, who initiate the delivery process, forwarders who manage and optimize deliveries, carriers who physically transport goods, and freight terminals that facilitate cargo handling and storage. …”
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Multifunctional Synthetic Poly(-Glutamic Acid)–Based Cancer Therapeutic and Imaging Agents by Marites P. Melancon, Chun Li

“…Having both an anticancer drug and an imaging reporter in a single polymer chain allows noninvasive real-time visualization of the pharmacokinetics of polymeric drug delivery systems, which can uncover and explain the complicated mechanisms of in vivo drug delivery and their correlation to pharmacodynamics. …”
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Comparison of the Infectivity and Transmission of Contemporary Canine and Equine H3N8 Influenza Viruses in Dogs by Heidi L. Pecoraro, Susi Bennett, Kristina Garretson, Ayshea M. Quintana, Katharine F. Lunn, Gabriele A. Landolt

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The history of childbirth: Women and doctors in the lying-in hospital of Göttingen University, eighteenth – nineteenth century by Jürgen Schlumbohm

“…Most doctors were willing to attend deliveries themselves only with well-todo ‘private’ patients, and in difficult cases. …”
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Expectant Management of a Critically Ill Pregnant Patient with COVID-19 with Good Maternal and Neonatal Outcomes by Farah Alsayyed, Victoria Hastings, Sanford Lederman

“…She had a full-term spontaneous vaginal delivery of a baby boy at 39 weeks gestation with excellent maternal and fetal outcomes at delivery. …”
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A comprehensive insight of innovations and recent advancements in nanocarriers for nose-to-brain drug targeting by Naeem Mubarak, Muhammad Ahsan Waqar, Asad Majeed Khan, Zainab Asif, Aima Subia Alvi, Aqsa Arshad Virk, Sakeena Amir

“…Nanotechnology has brought forward innovative solutions to the challenges of drug delivery in CNS disorders. Nanocarriers such as liposomes, nanoparticles, nanoemulsions and dendrimers can enhance drug stability, bioavailability, and targeted delivery to the brain. …”
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Microlearning beyond boundaries: A systematic review and a novel framework for improving learning outcomes by Wali Khan Monib, Atika Qazi, Rosyzie Anna Apong

“…Based on Andragogy in Practice Model, Bloom's Taxonomy, and Sweller's CLT, we proposed a novel microlearning instructional design framework consisting of three integral components—differences consisting of individual, situational, and subject differences; guiding principles including specific-objective, bite-sized content, appropriate timeframe, interactive and engaging content, personalization, and selecting appropriate delivery medium and mode; and learning outcomes (cognitive, behavioural and affective). …”
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Pilot of a team-based quality improvement strategy to improve cardiovascular risk factors care in community mental health centers by Karly A. Murphy, Karly A. Murphy, Joseph Gennusa, Arlene T. Dalcin, Arlene T. Dalcin, Courtney Cook, Courtney Cook, Stacy Goldsholl, Tyler Fink, Gail L. Daumit, Gail L. Daumit, Gail L. Daumit, Gail L. Daumit, Gail L. Daumit, Gail L. Daumit, Nae-Yuh Wang, Nae-Yuh Wang, Nae-Yuh Wang, Nae-Yuh Wang, Nae-Yuh Wang, David Thompson, David Thompson, Emma E. McGinty

“…Long term investments are needed to support organizational quality improvement work and providers’ efficacy to delivery - evidence-based CVD risk factor care delivery.Clinical Trial Registrationhttp://www.ClinicalTrials.gov, identifier NCT04696653.…”
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The Effect of Nutritional Mobile Apps on Populations With Cancer: Systematic Review by Krystal Lu Shin Ng, Murallitharan Munisamy, Joanne Bee Yin Lim, Mustafa Alshagga

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The feasibility of a novel national quality improvement programme for tobacco dependency treatment pathways in acute UK hospitals by Robyn Fletcher, Alexander Hammant, Christina Moll, Miguel Souto, Sanjay Agrawal

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Intravitreal Devices for the Treatment of Vitreous Inflammation by John B. Christoforidis, Susie Chang, Angela Jiang, Jillian Wang, Colleen M. Cebulla

“…The eye is a well-suited organ for local delivery of therapeutics to treat vitreous inflammation as well as other pathologic conditions that induce visual loss. …”
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Depressive Symptoms and Resilience among Pregnant Adolescents: A Case-Control Study by Danny Salazar-Pousada, Dalton Arroyo, Luis Hidalgo, Faustino R. Pérez-López, Peter Chedraui

“…Logistic regression analysis could not establish any risk factor for depressed mood among studied subjects; however, having an adolescent partner (OR, 2.0 CI 95% 1.06–4.0, P=.03) and a preterm delivery (OR, 3.0 CI 95% 1.43–6.55, P=.004) related to a higher risk for lower resilience. …”
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Maternal healthcare service utilisation and associated factors among mothers in a rural Wolaita, southern Ethiopia: a community-based cross-sectional study by Wondimagegn Paulos Kumma, Abera Kuche

“…The frequency of maternal healthcare service utilisation was positively related to having a favourable attitude towards maternal healthcare service utilisation, knowledge of mothers about maternal healthcare, walking distance to healthcare facilities in 30 and 30–60 min from residence and joint decision by mothers and their husbands on the place of delivery.Conclusion The proportion of maternal healthcare service utilisation in the study area was low, exacerbated by lower ANC, delivery care and PNC. …”
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The Effect of Pregnancy in the Hemoglobin Concentration of Pregnant Women: A Longitudinal Study by Berhanu Elfu Feleke, Teferi Elfu Feleke

“…The objective of this study was to estimate and identify the determinants of hemoglobin concentration before pregnancy, during pregnancy, and after labor and delivery. Methods. A prospective cohort study design was implemented. …”
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Perbandingan Nilai Apgar antara Persalinan Normal dengan Seksio Sesarea Elektif by Neila Azka, Syahredi ., Eva Chundrayetti

“…The 5th minute Apgar score of  4-6 in normal vaginal delivery was 1.1%, and Apgar score 7-10 was 98.9% in normal vaginal delivery while in cesarean section was 100%. …”
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