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5341
Quantitative Validation of Hematocrit Percentage Drop Cutoff Points in Postpartum Hemorrhage: An Automated Gravimetric Approach
Published 2025-01-01“…Blood loss was measured by an automated gravimetric system integrated into a suction blood collector and surgical gauze weighing systems to automatically sum up blood loss immediately after hysterectomy and fetal delivery. The percentage drop in hematocrit was determined by subtracting the 8-hour postsurgical from presurgical hematocrit, divided by presurgical hematocrit. …”
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5342
How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach
Published 2025-02-01“…Moreover, the geographic variation was a significant issue affecting the sustainable and balanced performance of public health delivery system in China. The spatially heterogeneous associations between macro-regional factors and efficiency provide in-depth insights in assisting local governments to formulate more targeted and effective interventions, thereby contributing to reduce regional disparities.…”
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5343
Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy
Published 2025-01-01“…Targeting SLC1A5 through advanced drug delivery systems and combined metabolic-immunotherapeutic strategies may enhance treatment specificity and efficacy. …”
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5344
Temporal changes in plasma and milk lipids in response to an esophageal bolus of rumen-protected fish oil in lactating Holstein dairy cows
Published 2025-02-01“…A 7-d washout period was utilized between each bolus delivery. Extracted plasma was analyzed for individual FA and phospholipid concentrations using gas chromatography and mass spectrometry. …”
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5345
Magnesium ions regulate the Warburg effect to promote the differentiation of enteric neural crest cells into neurons
Published 2025-01-01“…The GelMA-ALMA hydrogel serves as an effective localized magnesium delivery system, supporting neuronal differentiation in vivo. …”
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5346
Gelatin-stabilized traditional emulsions: Emulsion forms, droplets, and storage stability
Published 2020-12-01“…Fish oils are important substances in the field of food and drug delivery. Due to their unstable double bonds, fishy taste, and poor water solubility, it is pivotal to investigate novel dosage forms for fish oils, such as encapsulated droplets. …”
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5347
Metformin for Treating Gestational Diabetes: What Have We Learned During the Last Two Decades? A Systematic Review
Published 2025-01-01“…Regarding additional maternal outcomes, such as pregnancy-induced hypertension and cesarean deliveries, some studies demonstrate a link between metformin and a reduced occurrence of both conditions. …”
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5348
Sustainability of healthcare system improvements, programmes and interventions in acute care settings: protocol for a mixed methods systematic review
Published 2025-02-01“…The aim of this review is to identify facilitators and barriers that influence the delivery of sustained healthcare interventions (eg, integration of clinical guidelines) within adult and paediatric hospital-based acute care settings.Methods and analysis A mixed methods systematic review updating Cowie et al’s (which included studies from 2008 to 2017) previously published systematic review will be conducted. …”
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5349
Korelasi Kadar Hemoglobin dengan Kadar Nitric Oxide pada Preeklamsia dan Kehamilan Normal
Published 2015-09-01“…This<br />research was conducted in the clinic, emergency room, and delivery room of Dr. M. Djamil Hospital Padang and Reksodiwiryo Hospital in Padang from 13 th May to 13 th July 2014. …”
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5350
Engagement With an Internet-Administered, Guided, Low-Intensity Cognitive Behavioral Therapy Intervention for Parents of Children Treated for Cancer: Analysis of Log-Data From the...
Published 2025-01-01“…ConclusionsStraightforward techniques, such as behavioral activation, may be well-suited for digital delivery, and more complex techniques, such as worry management, may require modifications to improve user engagement. …”
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5351
Characteristics and outcomes of out-of-hospital cardiac arrest among students under school supervision in Japan: a descriptive epidemiological study (2008–2021)
Published 2025-01-01“…Initiation of cardiopulmonary resuscitation by bystanders was less common in non-cardiac and traumatic cases (62.6% and 42.0%, respectively) than that in cardiac cases (82.8%; p < 0.001). The delivery of defibrillation using public-access automated external defibrillators was also significantly less frequent in non-cardiac (3.3%) and traumatic cases (6.2%) than that in cardiac cases (59.8%; p < 0.001). …”
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5352
The Long-Term Immunity of a Microneedle Array Patch of a SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice
Published 2025-01-01“…Results: The rS1RS09 vaccine elicited stronger immune responses and ACE2-binding inhibition than S1 monomer alone or trimer. The MAP delivery induced sgnificantly higher and longer-lasting S1-specific IgG responses for up to 70 weeks compared to intramuscular injections. …”
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5353
Genetically Engineered Bacterial Ghosts as Vaccine Candidates Against <i>Klebsiella pneumoniae</i> Infection
Published 2025-01-01“…BGs are considered vaccine candidates, promising delivery systems, and vaccine adjuvants. The practical use of BGs in vaccine development for humans is limited because of concerns about the preservation of viable bacteria in BGs. …”
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5354
An innovative approach to prioritizing soil conservation areas under diverse scenarios by leveraging the complementary roles of soil retention services and soil erosion indicators
Published 2025-02-01“…Few studies consider multiple scenarios. The Sediment Delivery Ratio model was used to estimate soil conservation services (Avoided Erosion, AE; Sediment Trapping, ST) and soil erosion (Soil Loss, SL; Sediment Export, SE). …”
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5355
Comparison and verification of detection accuracy for late deceleration with and without uterine contractions signals using convolutional neural networks
Published 2025-01-01“…These results are expected to improve fetal outcomes by promptly alerting obstetric healthcare providers to signs of nonreassuring fetal status, even when the UC signal quality is poor, and encouraging them to monitor closely and prepare for emergency delivery.…”
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5356
The prevalence and distribution of malaria in Mpumalanga Province before and during COVID-19 (2017 - 2022)
Published 2024-08-01“…This study highlighted the impact of COVID-19 and its related lockdown restrictions on the delivery of malaria health services in Mpumalanga Province. …”
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5357
Reduction of Lipid-Core Burden Index in Nonculprit Lesions at Follow-Up after ST-Elevation Myocardial Infarction: A Randomized Study of Bioresorbable Vascular Scaffold versus Optim...
Published 2021-01-01“…Bioresorbable vascular scaffold (BVS) provides local drug delivery and could facilitate plaque passivation after resorption. …”
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5358
Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune respo...
Published 2025-01-01“…Importantly, intranasal immunization with HMP-NPs, without any adjuvant, induced efficient mucosal IgA responses and conferred complete protection against the H3N2 virus, as well as partial protection against the H1N1 and H9N2 viruses and significantly reduced lung viral loads.DiscussionOverall, our results indicated that the self-assembled nanovaccines increased the potency and breadth of the immune response against various influenza viruses and are a promising delivery platform for developing vaccines with broader protection against emerging influenza viruses and other pathogens.…”
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5359
Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology
Published 2025-01-01“…By analyzing the genetic factors influencing silk protein expression, this review further elaborates on the innovative applications of silk proteins in drug delivery systems, tissue engineering and regenerative medicine (eg, skin, bone, cartilage, and vascular repair), as well as antibacterial immune strategies. …”
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5360
The p110α and p110β Isoforms of Class I Phosphatidylinositol 3-Kinase Are Involved in Toll-Like Receptor 5 Signaling in Epithelial Cells
Published 2010-01-01“…Using a plasmid-based shRNA delivery system and novel p110 isoform-specific inhibitors, we found that flagellin-induced IL-8 production was dependent on both p110α and p110β. …”
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