Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus by Brézellec, Pierre

“…We first show that the C-terminal part of Spike S (the protein that binds the virion to the cell membrane by interacting with the host receptor, triggering infection) has similarities with the human prominin-1/CD133; after reviewing what is known about prominin-1/CD133, we suggest that the C-terminal part of Spike S could both improve the docking of Spike S to ACE2 (the main cell entry receptor for SARS-CoV-2) and be involved in the delivery of virions to regions where ACE2 is located in cells. …”
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In situ template synthesized silver nanoparticulate banana fibre materials with antimicrobial and antibiotic release properties: Efficacy evaluation in ex vivo wound infection mode... by Pompi Das, Debajit Mahanta, Sharmila Giogi, Tarh Kaha, Ngurang Nisha, Sanjeeb Kalita

“…These findings establish BF-SNP, BFS-SNP, and BFM-SNP as promising candidates for antimicrobial wound care applications and controlled drug delivery systems, offering a sustainable, bioresource-based solution for advanced biomedical materials.…”
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Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review by Lou’i Al-Husinat, Shrouq Obeidat, Saif Azzam, Yara Al-Gwairy, Fatima Obeidat, Sarah Al Sharie, Deema Haddad, Fadi Haddad, Martina Rekatsina, Matteo Luigi Giuseppe Leoni, Giustino Varrassi

“…This review examines the use of cannabis in managing chronic non-cancer pain, focusing on its benefits, drawbacks, mechanisms, delivery methods, and impact on quality of life.…”
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Successful Pregnancy Outcome in a Patient Treated with Pembrolizumab and Exposed to Fluoro-Deoxyglucose (¹⁸F-FDG) PET/CT: Case Report and Review of Literature by Anna Lucia Mastricci, Felice Sorrentino, Elisa Giansiracusa, Erika Zanzarelli, Graziana Silvana De Lucia, Vincenza Fernanda Fesce, Luigi Nappi, Lorenzo Vasciaveo

“…Following multidisciplinary counseling, the pregnancy was closely monitored, culminating in the delivery of a healthy male infant at 37.5 weeks. <b>Conclusions</b>: This case highlights a favorable maternal–fetal outcome despite exposure to pembrolizumab and ¹⁸F-FDG PET/CT during pregnancy. …”
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Hybrid Nanocomposite Mini-Tablet to Be Applied into the Post-Extraction Socket: Matching the Potentialities of Resveratrol-Loaded Lipid Nanoparticles and Hydroxyapatite to Promote... by Viviana De Caro, Giada Tranchida, Cecilia La Mantia, Bartolomeo Megna, Giuseppe Angellotti, Giulia Di Prima

“…This study aims to develop a solid nanocomposite by embedding RSV in lipid nanoparticles (mLNP) within a hydrophilic matrix, to the scope of improving local delivery and enhancing healing. Hydroxyapatite (HXA), often used as a bone substitute, was added to prevent post-extraction alveolus volume reduction. …”
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Implications of the availability and distribution of birth weight on addressing neonatal mortality: population-based assessment from Bihar state of India by Lalit Dandona, Rakhi Dandona, G Anil Kumar, Debarshi Bhattacharya, Sibin George, Priya Nanda, Md Akbar

“…Variations of LBW by place of delivery and sociodemographic indicators, and the perceptions of carers about LBW can facilitate appropriate actions to address LBW and the associated neonatal mortality.…”
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The Impact of Rural Alimentation on the Motivation and Retention of Indigenous Community Health Workers in India: A Qualitative Study by Ajit Kerketta, Raghavendra A N

“… Abstract BackgroundRural health care delivery remains a global challenge and India is no exception, particularly in regions with Indigenous populations such as the state of Jharkhand. …”
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Carthamin yellow-loaded glycyrrhetinic acid liposomes alleviate interstitial fibrosis in diabetic nephropathy by Yifei Wang, Wenfang He, Peiyao Ren, Li Zhao, Danna Zheng, Juan Jin

“…The inhibitory effects were stronger than CY alone and were mediated by the inactivation of the TGFBR1/Smad2/Smad3 pathway, as confirmed by TGFBR1 overexpression studies.Conclusions CY-loaded GA liposomes demonstrated significant therapeutic efficacy in alleviating renal interstitial fibrosis in DN by targeting the TGFBR1/Smad2/Smad3 pathway. This novel drug delivery system provides a promising approach for the treatment of DN.…”
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Freedom of expression, aspiration and gender: A cultuling in the student demonstration by Siti Nurbayani, Elly Malihah, Millary Agung Widiawaty, Moh. Dede, Bayu Iqbal Anshari, Asep Mahpudz, Erry Sukriah, Sri Wahyuni

“…The conceptual model of cultuling analysis, which encompasses delivery, emotional, and cultural values with 16 parameters, was used to analyze the data. …”
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Validation of a Questionnaire Assessing Pregnant Women’s Perspectives on Addressing the Psychological Challenges of Childbirth by Mihaela Corina Radu, Mihai Sebastian Armean, Razvan Daniel Chivu, Justin Aurelian, Melania Elena Pop-Tudose, Loredana Sabina Cornelia Manolescu

“…This study explores the psychological and emotional factors influencing pregnant women’s decisions regarding their mode of delivery. The results will provide valuable insights for the development of educational and counseling strategies designed to support pregnant women in making informed and conscious decisions about their childbirth. …”
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Frequency and persistency of DNA vaccine encoding GP25 by oral on common carp by Sri Nuryati, , Yuliyanti, , Alimuddin

“…The aim of this research was to get frequency and persistency of DNA vaccine encoding GP25 given by oral delivery method in common carp. This research would like to determine dose, frequency of vaccination, persistency of DNA vaccine and culture medium for the bacterial host. …”
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Use of the SONET Score to Evaluate High Volume Emergency Department Overcrowding: A Prospective Derivation and Validation Study by Hao Wang, Richard D. Robinson, John S. Garrett, Kellie Bunch, Charles A. Huggins, Katherine Watson, Joni Daniels, Brett Banks, James P. D’Etienne, Nestor R. Zenarosa

“…ED overcrowding negatively impacts patient care operations and often produces poor patient perceptions of standardized care delivery.…”
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Pilates exercise in pregnancy: a systematic review and meta-analysis by Yuxuan Li, Heran Lu, Liuwei Zhang, Yijia Ren, Xiaotong Dai, Lin Lin

“…Among these, 3 studies exhibited a low risk of bias, while 8 studies presented an unclear risk of bias. (2) The meta-analysis results indicated that Pilates exercise resulted in non-significant changes in the Body Mass Index (BMI) of pregnant women (SMD 0.02; 95% CI, -0.27 to 0.31; P = 0.887), the body weight of pregnant women (SMD 0.25; 95% CI, -0.52 to 1.02; P = 0.519), the mode of delivery (RR 1.41; 95% CI, 0.95 to 2.09; P = 0.093), and the Low-density lipoprotein (LDL) levels of pregnant women (SMD − 1.182; 95% CI, -2.443 to 0.079; P = 0.066). …”
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The Evaluation of Change in Psychosocial Risk With Caregivers of Children With Chronic Kidney Disease: A Short-term Longitudinal Mixed-Methods Study by Caroline C. Piotrowski, Kira Kudar, Julie Strong, Ashley Giesbrecht, Anne Kazak, Katerina Pappas, Gina Rempel, Aviva Goldberg

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From the Banks of the Orkhon to the Banks of the Neva: the History of Mining and Transit of Mongolian Gold to the Russian Empire at the beginning of the 20th century. by Aldar A. Shirapov, Anna M. Plekhanova

“…The purpose of the research is to study the mechanism of delivery of Mongolian gold to the Russian territory; identify and evaluate the role of the Russo-Chinese Bank and the Kyakhtinsky District Treasury in this process. …”
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Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a q... by John Bosco Alege, John Paul Oyore, Rose Clarke Nanyonga, Philippa Musoke, Alloys S. S. Orago

“…The study participants (Key Informants) were both clinical and administrative health workers involved in the delivery of Hepatitis B, C, and HIV services. Data was audio recorded using a recording device and then transcribed after all interviews were conducted. …”
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A Novel Approach for In Vitro Testing and Hazard Evaluation of Nanoformulated RyR2-Targeting siRNA Drugs Using Human PBMCs by Valeria Bettinsoli, Gloria Melzi, Angelica Crea, Lorenzo Degli Esposti, Michele Iafisco, Daniele Catalucci, Paolo Ciana, Emanuela Corsini

“…This compound and its scramble were formulated within a calcium phosphate nanoparticle-based delivery system. Positive controls for four toxicity pathways were identified through literature review, each associated with a specific type of cellular stress: oxidative stress (tert-butyl hydroperoxide), mitochondrial stress (rotenone), endoplasmic reticulum stress (thapsigargin), and autophagy (rapamycin). …”
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Evaluation of reproductive and oncological outcomes after fertility-sparing surgery in cervical cancer patients with tumor > 2 cm by Kiarash Bahrehmand, Dóra Vesztergom, Barna Budai, Dániel Lengyel, Edina Lukács, Zoltán Novák

“…Out of the 14, 64.3 % (9/14) tried to conceive, resulting in 2 successful deliveries after in vitro fertilization resulting a live birth rate of 22.2. …”
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Gestational Diabetes Mellitus Does Not Change the Pharmacokinetics and Transplacental Distribution of Fluoxetine and Norfluoxetine Enantiomers by Daniela Miarelli Carvalho, Glauco Henrique Balthazar Nardotto, Gabriela Campos de Oliveira Filgueira, Geraldo Duarte, Ricardo Carvalho Cavalli, Vera Lucia Lanchote, Elaine Christine Dantas Moisés

“…They received a single oral dose of 20 mg FLX, and blood samples were collected from 0 to 672 h. On the day of delivery, after another single oral dose of 20 mg FLX, blood samples of maternal vein, umbilical vessels and intervillous space were collected at birth. …”
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Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial by Hugh Taylor, Hao Huang, Lubna Pal, Heping Zhang, Howard J Li, Sandra Carson, Valerie Flores, Jared Robbins, Nanette F Santoro, James H Segars, David Seifer, Steven Young

“…Secondary outcomes include oocyte number, fertilisation rate, embryo morphology and implantation rates, as well as rates of known endometriosis-related obstetrical outcomes (pregnancy-induced hypertension, antepartum haemorrhage, caesarean delivery and preterm birth).Ethics and dissemination The PREGnant trial was approved by the Institutional Review Board at Johns Hopkins University. …”
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