A randomised trial comparing preoperative administration of single-dose kefazolin to kefazolin plus metronidazole as prophylactic antibiotics at caesarean section by R Lamfel, L Snyman, L Seopela, G Jahn, P Becker

“…The risk of postpartum infection is estimated to be five to ten times higher compared with normal vaginal delivery. Pregnancy-related sepsis was listed as a top-six cause of maternal mortality in the South African Saving Mothers report between 2017 and 2019. …”
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Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020 by Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie

“…Strategies such as combination therapy, structural optimization, and drug delivery systems are anticipated to enhance efficacy and overcome these challenges.…”
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Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model by Maria Fernanda Yepes, Kayla Minesinger, Federica M. Raciti, Maria Camila Salazar, Suhrud M. Rajguru, Suhrud M. Rajguru, Suhrud M. Rajguru

“…This study assessed the efficacy of Z-VAD-FMK as a therapeutic for noise-induced cochlear injury in a rodent model.MethodsRodents were assigned to one of four groups: (1) unexposed, (2) noise-exposed, (3) noise + vehicle, and (4) noise + Z-VAD-FMK. Noise delivery consisted of 1 h of 110 dB continuous white-noise, with Z-VAD-FMK administered intraperitoneally 6 h afterward. …”
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Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by O. A. Koval, O. Y. Volkova, A. A. Gorchakov, S. V. Kulemzin, A. V. Tkachenko, A. A. Nushtaeva, E. V. Kuligina, V. A. Richter, A. V. Taranin

“…Taken together, our results provide an opportunity for developing armored immune cells as an “off-the-shelf” platform for targeted delivery of lactaptin to cancer cells.…”
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Exploring the Structural Diversity and Biotechnological Potential of the Rhodophyte Phycolectome by Éllen F. Rodrigues, Flavia Alves Verza, Felipe Garcia Nishimura, Renê Oliveira Beleboni, Cedric Hermans, Kaat Janssens, Maarten Lieven De Mol, Paco Hulpiau, Mozart Marins

“…Moreover, their diversity enables biotechnological exploration as biomarkers, biosensors, drug-delivery platforms, and lead molecules for anticancer, antidiabetic, and antimicrobial drugs. …”
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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer:... by Joachim G J V Aerts, Sjoerd H van der Burg, Martijn P Lolkema, Sai Ping Lau, Freek R van ’t Land, Marjolein Y V Homs, Casper H J van Eijck

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Hybrid Carbohydrate–Lipid Nanocarriers: In Vitro Efficacy Gene-Rated by Association of UV-Absorbers and Raspberry Polyphenols Rich-Fraction by Nicoleta Badea, Diego Samayoa, Alina Moroşan, Cristina Ott, Ioana Lacatusu

“…<b>Conclusions</b>: HA decorated-NLC-conditioned creams might provide a useful platform for developing na-tural and sophisticated dermal delivery systems, for influencing skin permeability, and for synergistically imparting antioxidant and photoprotective actions to cosmetic pro-ducts.…”
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Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy by Xinyang Shen, Yuan Ma, Hang Luo, Razack Abdullah, Yufei Pan, Yihao Zhang, Chuanxin Zhong, Baoting Zhang, Ge Zhang

“…By harnessing the unique properties of peptide aptamers, these conjugates demonstrate significant promise in improving drug delivery efficiency while reducing the adverse effects associated with traditional paclitaxel therapy. …”
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Mathematical Modelling of Acetaminophen Release in HPC/PAAm Hydrogel: Synthesis and Application by Abigail M. Díaz-Guerrero, Claudia A. Castillo-Miranda, Carlos F. Castro-Guerrero, Hernán Peraza-Vázquez, Ana B. Morales-Cepeda, Adrián F. Peña-Delgado

“…Hydrogels are commonly used as Drug Delivery Systems (DDS) as patches due to its ability to store drug molecules within their structures. …”
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Comparison of the Efficacy and Tolerability of Dienogest and Dienogest Plus Ethinylestradiol on Endometriosis Related-Pain by Tolga Karacan, Huseyin Kiyak, Eser Ozyurek, Mevlide San, Engin Oral

“…Various medical treatments with different doses, formulations, delivery systems, and regimens have been tested. The main objective of this study was to compare the efficacy and tolerability of dienogest and dienogest plus ethinylestradiol on endometriosis-related pain. …”
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Pan-Canadian assessment of image guided adaptive radiation therapy and the role of the radiation therapist by Amanda Moreira, Tara Rosewall, Yat Tsang, Patricia Lindsay, Peter Chung, Winnie Li

“…Purpose: Adaptive radiation therapy (ART) is a close-looped process where anatomic changes observed during treatment are identified, leading to plan modification prior to treatment delivery. The aim of this study was to explore the status of ART across Canada and review the impact of adaptive technologies on the roles and responsibilities of Radiation Therapists (RTTs). …”
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Global and Regional Burden of Type 2 Diabetes Mellitus Attributable to Low Physical Activity From 1990 to 2021 by Lihang Yang, Diya Xie, Fengmin Liu, Jiaying Lin, Xin Lin, Yuquan Chen, Kun Zhang

“…The findings lay the groundwork for informed decision‐making a public health and healthcare delivery.…”
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Navigating DR-TB Treatment care: a qualitative exploration of barriers and facilitators to retention in care among people with history of early disengagement from drug-resistant tu... by Ndiviwe Mphothulo, Sindisiwe Hlangu, Jennifer Furin, Mosa Moshabela, Marian Loveday

“…Abstract Background Despite advances in drug-resistant tuberculosis (DR-TB) diagnosis, treatment, and service delivery, individuals with DR-TB often face significant socioeconomic and psychosocial challenges due to limited resources. …”
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Simulation investigation of a Ka-band phase-locked klystron-type coaxial relativistic Cherenkov generator by Yunxiao Zhou, Jinchuan Ju, Wei Zhang, Dian Zhang, Ying Li, Tengfang Wang, Fugui Zhou, Zhuang Yu, Hongtao Yao, Jun Zhang

“…Phase locking of the output HPM is accomplished through phase delivery of the modulated IREB. Specially designed reflectors and cascaded single-gap bunching cavities with active suppression of asymmetric TM mode are employed in the pre-modulation region to suppress energy coupling and achieve a lower input power ratio. …”
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RETRACTED: Mycosynthesis of Hematite (α-Fe₂O₃) Nanoparticles Using <em>Aspergillus niger</em> and Their Antimicrobial and Photocatalytic Activities by Ebrahim Saied, Salem S. Salem, Abdulaziz A. Al-Askar, Fathy M. Elkady, Amr A. Arishi, Amr H. Hashem

“…Nanoparticles (NPs) and nanomaterials (NMs) are now widely used in a variety of applications, including medicine, solar energy, drug delivery, water treatment, and pollution detection. …”
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Hydrogen Supplementation of Preservation Solution Improves Viability of Osteochondral Grafts by Takuya Yamada, Kentaro Uchida, Kenji Onuma, Jun Kuzuno, Masanobu Ujihira, Gen Inoue, Bunpei Sato, Ryosuke Kurokawa, Rina Sakai, Masashi Takaso

“…Here, we evaluated whether long-term hydrogen delivery to preservation solution improved the viability of rat OCTs during cold preservation. …”
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Geographic information system and process-based modeling of soil erosion and sediment yield in agricultural watershed by G.R. Puno, R.A. Marin, R.C.C. Puno, A.G. Toledo-Bruno

“…At a watershed scale, the model predicted the erosion and sediment yield at 89 tons per hectare per year and 22 tons per hectare per year, respectively, which are far beyond the erosion tolerance of 10 tons per hectare per year. The sediment delivery ratio of 0.20 accounts for a total of 126,390 tons of sediments that accumulated downstream in a year.…”
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Enhancing Health Equity and Patient Engagement in Diabetes Care: Technology-Aided Continuous Glucose Monitoring Pilot Implementation Project by Madhur Thakur, Eric W Maurer, Kim Ngan Tran, Anthony Tholkes, Sripriya Rajamani, Roli Dwivedi

“…With the increasing adoption of technologies in health care delivery, digital tools for continuous glucose monitoring (CGM) are being used to improve disease management and increase patient engagement. …”
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Do Maternal Vitamin D Levels Influence Vitamin D Levels in Preterm Neonates? by M. Panda, J. McIntosh, T. Chaudhari, A. L. Kent

“…Maternal VitD levels were obtained within 3-4 days following delivery. Neonatal VitD levels were obtained in the first 3-4 days of life, at 3-4 weeks of age, and at 6-8 weeks of age. …”
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Hidden Metabolic Disturbances in Women with Normal Glucose Tolerance Five Years after Gestational Diabetes by Yvonne Winhofer, Andrea Tura, Anita Thomas, Thomas Prikoszovich, Christine Winzer, Giovanni Pacini, Anton Luger, Alexandra Kautzky-Willer

“…The study aimed to assess whether women with prior gestational diabetes (pGDM), despite maintenance of normal glucose tolerance (NGT) five years after delivery, display metabolic disturbances compared to healthy controls. …”
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