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4661
Superparamagnetic Bifunctional Bisphosphonates Nanoparticles: A Potential MRI Contrast Agent for Osteoporosis Therapy and Diagnostic
Published 2010-01-01“…A bone targeting nanosystem is reported here which combined magnetic contrast agent for Magnetic Resonance Imaging (MRI) and a therapeutic agent (bisphosphonates) into one drug delivery system. This new targeting nanoplatform consists of superparamagnetic γFe2O3 nanoparticles conjugated to 1,5-dihydroxy-1,5,5-tris-phosphono-pentyl-phosphonic acid (di-HMBPs) molecules with a bisphosphonate function at the outer of the nanoparticle surface for bone targeting. …”
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4662
Integrating High-Value Cost-Conscious Care into an Existing Medical School Curriculum
Published 2025-01-01“…Methods First-year medical student attitudes and understanding regarding HVCCC were evaluated via a survey before and after the delivery of a mixed asynchronous and in-person HVCCC curriculum created by two medical student peers. …”
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4663
Vagal nerve stimulation dynamically alters anxiety-like behavior in rats
Published 2025-03-01“…In contrast, higher-intensity VNS had no effect on c-Fos expression in noradrenergic neurons of either the nucleus of the solitary tract or locus coeruleus. Conclusion: Delivery of VNS induced reproducible, current intensity-dependent, effects on anxiety-like and aversive behavior in rats.…”
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4664
Hydrogel-Based Innovations in Carpal Tunnel Syndrome: Bridging Pathophysiological Complexities and Translational Therapeutic Gaps
Published 2025-01-01“…Their ability to mimic the extracellular matrix facilitates localized drug delivery, anti-adhesion barrier formation, and tissue regeneration. …”
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4665
Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report
Published 2025-02-01“…Iron Deficiency Anaemia (IDA) is a prevalent nutritional deficiency and a common haematological disorder characterised by low iron levels, which lead to reduced haemoglobin production, fatigue, pallor and diminished oxygen delivery. IDA increases the risk of venous thromboembolism by causing thrombocytosis, venous stasis and hypercoagulability. …”
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4666
Social and psychological features of the mental component of the modern hybrid war against Ukraine
Published 2024-06-01“…It is the information activity as a component of the hybrid war that involves a massive psychological impact on the emotional state of a person, the delivery of distorted information to the country’s population. …”
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4667
Animal Models for Human-Pathogenic Coronavirus and Animal Coronavirus Research
Published 2025-01-01“…These approaches include using viral delivery methods to induce the expression of viral receptors in mouse tissues and employing gene-editing techniques to create genetically modified mice. …”
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4668
Stem Cell–Based Therapies via Different Administration Route for Stroke: A Meta-analysis of Comparative Studies
Published 2025-02-01“…Non-IV routes showed more long-term benefits, potentially due to enhanced cell delivery and integration. These findings demonstrate the potential of stem cell therapies to improve functional recovery and survival in stroke patients, regardless of administration route. …”
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4669
Three-Dimensional Printable Magnetic Hydrogels with Adjustable Stiffness and Adhesion for Magnetic Actuation and Magnetic Hyperthermia Applications
Published 2025-01-01“…Stimuli-responsive hydrogels hold immense promise for biomedical applications, but conventional gelation processes often struggle to achieve the precision and complexity required for advanced functionalities such as soft robotics, targeted drug delivery, and tissue engineering. This study introduces a class of 3D-printable magnetic hydrogels with tunable stiffness, adhesion, and magnetic responsiveness, prepared through a simple and efficient “one-pot” method. …”
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4670
Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review
Published 2025-01-01“…<b>Background/Objectives:</b> Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. …”
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4671
Polymer-Free Electrospinning of β-Cyclodextrin–Oligolactide for Magnolol and Honokiol Pharmaceutical Formulations
Published 2025-01-01“…<b>Conclusions:</b> This study demonstrates the potential of MG and HK-loaded β-CDLA fibrous formulations as delivery systems with prolonged antioxidant activity and notable antibacterial efficacy, providing a promising platform for biomedical applications.…”
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4672
Assessing moisture content in XLPE power cables using frequency-dependent tangent delta measurements
Published 2025-01-01“…This research aims to develop a robust and accurate methodology for estimating moisture content in XLPE cable end terminations to enhance condition-based monitoring and ensure reliable power delivery. The study employed frequency domain spectroscopy to examine the dielectric properties of XLPE cable samples with varying moisture content levels. …”
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4673
Effect of scaling on levels of interleukin 1-beta and clinical periodontal parameters among e-cigarette users and non-smokers: A prospective study
Published 2024-07-01“…Methods Self-reported current electronic nicotine delivery system (ENDS) users and NS with generalized gingivitis were included in this study. …”
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4674
Vital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review
Published 2025-01-01“…Addressing these barriers could enable health kiosks to play a greater role in early disease detection and healthcare delivery.…”
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4675
Content analysis of food and beverage marketing in global esports: sponsorships of the premier events, leagues, teams and players
Published 2024-07-01“…Brands were then categorised based on product type into the following categories: energy drinks, sugar-sweetened beverages, alcohol, candy/snacks, restaurants, food delivery and stores, and supplements. The total number of brand sponsorships was then calculated for each product category.Results 90 unique food and beverage brands were identified. …”
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4676
Evaluating the cost-effectiveness of prosthetic rehabilitation for partially edentulous teeth in India: A comparative study of Clasp-Retained RPDs, Thermoplastic Resin RPDs, and Ca...
Published 2025-03-01“…The Oral Health Impact Profile (OHIP-14) and Satisfaction Questionnaire (SAT) were administered at baseline and three months post-denture delivery. The study adhered to Consolidated Health Economic Evaluation Reporting Standards. …”
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4677
Biocompatible and Biodegradable Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Prepared via Semicontinuous Heterophase Polymerization: Kinetics and Produc...
Published 2016-01-01“…Because of their biocompatibility and biodegradability as well as their extremely small size these nanoparticles could be used as vehicles for improved drug delivery in the treatment of chronic-degenerative diseases.…”
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4678
Future directions of spiritual care where spiritual care providers do not exist: a qualitative study
Published 2025-01-01“…The findings suggest establishing structured training programs and interdisciplinary collaboration are crucial for effective spiritual care delivery. Conclusion The study emphasises the need for integrating spiritual care into Thailand’s healthcare system, focusing on education, research, and collaboration between healthcare providers and religious or community figures. …”
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4679
Luminescence enhancement of Y2O3:Er3+ and Y2O3:Yb3+/Er3+ sub-microcrystals by Zr4+ ions Co-doping
Published 2025-06-01“…This research contributes to the understanding of UC luminescent properties of lanthanide (Ln3+) ions doped UC materials and their technological applications in fields such as bioimaging, drug delivery, and optical temperature sensors.…”
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4680
Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance
Published 2017-12-01“…In addition, results of the in vivo skin performance study supported acceptable tolerability for all investigated formulations, suggesting selected microemulsions as promising carriers worth exploring further for effective skin delivery of model drugs.…”
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