Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro by Han T, Jia T, Wang J

“…Thus, this study aims to explore the adaptive evolution characteristics underlying linezolid resistance in MRSA clinical isolates exposed to continuous induction stress of linezolid in vitro.Methods: The in vitro susceptibility of 1032 MRSA clinical isolates to linezolid was detected using commercial VITEK-2 equipment via broth microdilution. …”
Get full text

TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis by Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang

“…Western blotting was employed to detect proteins related to cuproptosis and apoptosis, while ubiquitination assays assessed TWIST1's regulation of HK2 ubiquitination. …”
Get full text

An overview of hereditary spherocytosis and the curative effects of splenectomy by Kyril Turpaev, Elizaveta Bovt, Elizaveta Bovt, Soslan Shakhidzhanov, Soslan Shakhidzhanov, Elena Sinauridze, Elena Sinauridze, Nataliya Smetanina, Larisa Koleva, Larisa Koleva, Nikita Kushnir, Nikita Kushnir, Anna Suvorova, Fazoil Ataullakhanov, Fazoil Ataullakhanov, Fazoil Ataullakhanov

“…The causes of hereditary spherocytosis are mutations in genes that encode red blood cell (RBC) membrane and cytoskeletal proteins, including ankyrin-1, Band 3 (or AE1), α spectrin, β spectrin, and protein 4.2. Molecular defects in these proteins decrease membrane integrity, leading to vesiculation, decreased membrane surface area, and reduced deformability of the cells. …”
Get full text

Comparative Analysis of AES, Blowfish, Twofish, Salsa20, and ChaCha20 for Image Encryption by Rebwar Khalid Muhammed, Ribwar Rashid Aziz, Alla Ahmad Hassan, Aso Mohammed Aladdin, Shaida Jumaah Saydah, Tarik Ahmed Rashid, Bryar Ahmad Hassan

“…The recognition of threats and attacks meant for knowledge and safety on the internet is growing harder to detect. Since cybersecurity guar-antees the privacy and security of data sent via the Internet, it is essential, while also providing protection against malicious attacks. …”
Get full text

Folic acid supplementation during preconception period in sub-Saharan African countries: A systematic review and meta-analysis. by Mekuriaw Nibret Aweke, Elsa Awoke Fentie, Muluken Chanie Agimas, Lemlem Daniel Baffa, Ever Siyoum Shewarega, Aysheshim Kassahun Belew, Esmael Ali Muhammad, Berhanu Mengistu

“…<h4>Introduction</h4>Neural tube defects (NTDs) are serious congenital anomalies of the central nervous system caused by disruptions in early embryonic development. …”
Get full text

Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi by Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey

“…Although high homing rates were observed, the fitness defects found in both males and females carrying the transgene would likely prohibit this drive from functioning in the field. …”
Get full text

Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…Moreover, adrenal paraganglioma (PGL) (82.35% vs. 17.65%; p = 0.0001) and pancreatic neuroendocrine tumor (PNET) (81.81% vs. 18.18%; p = 0.007) were associated with missense VHL pathogenic or likely pathogenic variants compared with non-missense defects. In contrast, central nervous system (CNS) hemangioblastomas (HBs) (90.47% vs. 53.12%; p = 0.004), pancreatic cysts (76.19% vs. 28.12%; p = 0.001) and RCCs (57.14% vs. 12.5; p = 0.001) were more common in patients with non-missense VHL variants. …”
Get full text

Small Intestinal Bacterial Overgrowth Syndrome as a Risk Factor for Ventricular Tachycardia in Chronic Heart Failure with Left Ventricular Systolic Dysfunction by M. V. Fadeeva, M. R. Skhirtladze, V. T. Ivashkin

“…Lactulose hydrogen breath test was fulfiled to detect the small intestinal bowel bacterial overgrowth syndrome (SIBOS). …”
Get full text

Physiological and transcriptome analysis reveals the mechanism of Gymnocarpos przewalskii response to drought stress by Chao Du, Xinyu Ni, Mengjiao Yan, Qinghan Meng, Junying He

“…(G. przewalskii) is an endangered xerophytic shrub that plays a crucial role as a source of forage in the Alxa Desert. However, there is limited understanding regarding the forage quality of G. przewalskii and its response to drought. …”
Get full text

Evidence of vancomycin-resistant Staphylococcus aureus, multidrug-resistant S. aureus, and Enterococcus faecium-causing mastitis in Thailand and Cambodia by Sambo Na, Montira Intanon, Anyaphat Srithanasuwan, Wasana Chaisri, Witaya Suriyasathaporn

“…Disk diffusion tests were conducted for antibiotic susceptibility, and polymerase chain reaction was employed to detect AMR genes. Results: S. aureus isolates showed resistance to penicillin (21.8%), tetracycline (9.1%), and gentamycin (7.3%). …”
Get full text

Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

“…Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) and western blotting were utilized to detect the ITGB2 expression. Then the cell viability, inflammatory factors, and the expression of epithelial–mesenchymal transition (EMT) and fibrosis markers were determined by using Cell Counting Kit-8 (CCK-8) assay, enzyme linked immunosorbent assay (ELISA), western blotting assays, respectively. …”
Get full text

Assessment of vegetation in Murchison falls national park five years after the completion of oil and gas exploration by Hindrah Akisiimire, William Tinzaara, Keneth Tumwebaze, Charles K.Twesigye

“…However, the study observed some plant species such as Desert date (Balanites aegyptiaca) in control areas that were completely absent in oil pads. …”
Get full text

LncRNA GAS5 inhibits glioma progression through miR-135b-5p/APC axis by ZHANG Jidong, WANG Yutao, JI Jianwen

“…Methods‍　‍The relationship of GAS5 expression level with survival rate of glioma patients was analyzed based on CGGA database. qRT-PCR was used to detect the expression level of GAS5 in glioma tissues and cell lines. …”
Get full text

Pengamanan Citra Berwarna Menggunakan Kriptografi Visual Skema Meaningful Shares dan Steganografi LSB by Fariz Abid Darmawan, Ari Kusyanti, Rakhmadhanny Primananda

“…This is proven from the test by calculating the PSNR values of the stego image, where the PSNR results are between 32-33 dB. for security by using Autopsy and Stegspy only 3 stego images can detect the share image, this is only a share image, and to reconstruct the secret image it takes a pair of shares,  so it can be concluded that this combining method successfully secures the secret image in it.…”
Get full text

Deteksi Objek menggunakan Dashboard Camera untuk Sistem Peringatan Pencegah Kecelakaan pada Mobil by Raymond Sutjiadi, Timothy John Pattiasina

“…This application was developed using Object Detection Method in Tensorflow Open Source Machine Learning Library. …”
Get full text

Sistem Pendeteksi Sleep-Disordered Breathing Berdasarkan High dan Low Frequency Menggunakan Metode Naïve Bayes by Achmad Ghifari, Edita Rosana Widasari

“…Therefore, in this research, a system was created to detect sleep disorders into Normal, OSA, or CSA classes using Electrocardiography (ECG) signals acquired by the 3-lead placement technique. …”
Get full text

The application of emerging technologies for the quality and safety evaluation of oilseeds and edible oils by Xue Li, Wenwen Liu, Lu Xiao, Jie Zhao, Yan Chen, Liangxiao Zhang, Peiwu Li, Dolores Pérez-Marín, Xu Wang

“…Classical techniques widely used to detect the safety and quality attributes of oilseeds and edible oils often involve time-consuming and tedious operation; therefore, the development of low cost, rapid and non-destructive detection method is necessary. …”
Get full text

Metabolite profiling in assessing ulcerative colitis activity: A systematic review by Danyang Cui, Xu Han, Jiazhu Jin, Yanhong Wang, Zijia Chen, Yang Gong, Miao Jiang

“…Background: Ulcerative colitis (UC) is an immune-mediated chronic inflammatory condition of the colon, characterized by defects in the intestinal epithelial barrier, dysbiosis of the microbiota, and immune dysregulation. …”
Get full text

The Role of Physical Activity in Pregnancy: Impact on Preeclampsia, Gestational Diabetes Mellitus, and Labor Outcomes by Paulina Woźniak, Ewa Wietrzykowska, Wiktoria Gajek-Flanczewska, Sebastian Flanczewski, Małgorzata Wirkijowska, Jakub Wirkijowski, Katarzyna Wójtowicz, Agata Walczak, Dominika Sobolewska, Katarzyna Michalczyk-Fraszka, Martyna Śliwińska, Anna Podraza

Get full text

Hepatobiliary organoid research: the progress and applications by Rui-Qi Zou, Rui-Qi Zou, Yu-Shi Dai, Yu-Shi Dai, Fei Liu, Fei Liu, Si-Qi Yang, Si-Qi Yang, Hai-Jie Hu, Hai-Jie Hu, Fu-Yu Li, Fu-Yu Li

“…Despite advances in research and treatment, hepatobiliary diseases including carcinoma, viral hepatitis, fatty liver and bile duct defects have still been conundrums of the hepatobiliary field. …”
Get full text