Association of HLA-B27 Gene and Rheumatoid Arthritis: Analysis of Potential Role as a Predictive Biomarker by Karzan Ghafur Khidhir, Baban Ahmad, Dana Khdr Sabir

“…This study investigated the relative expression of HLA-B27 gene in RA patients compared to normal control and assesses its suitability as a biomarker for early detection of RA. Bioinformatics analysis was used to determine the profile of HLA-B27 gene in different human tumors to demonstrate the possible involvement of HLA-B27 in both RA and cancer; and also, to discover its functional association with other human genes. …”
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Characterization of New Particle Formation in Soft X-ray Radiolysis Reactor: AMCs-to-Secondary Inorganic Aerosols by Jiyoon Shin, Kyungil Cho, Yoonkyeong Ha, Giwon Kang, Jihye Park, Hunkwan Park, Changhyuk Kim

“…Soft X-ray radiolysis was developed to detect AMCs as low as the ppt-level by forming secondary aerosols from AMCs under soft X-ray irradiation. …”
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Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent by Korfmann, Kevin, Sellinger, Thibaut Paul Patrick, Freund, Fabian, Fumagalli, Matteo, Tellier, Aurélien

“…The current methods developed to detect such multiple merger events do not account for complex demographic scenarios or recombination, and require large sample sizes. …”
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Causal associations between socioeconomic status and prostate cancer using two-sample Mendelian randomization study by Zhenxing Wang, Chunyan Wang, Xing Gou, Liang Pei, Xiaoyuan Qiao

“…We employed the inverse variance weighted (IVW), weighted median, weighted mode and MR-Egger to estimate the causal effect, with sensitivity analyses such as Cochran’s Q tests, MR-Egger, MR-PRESSO and leave-one-out performed to detect potential heterogeneity and pleiotropy. Our MR analysis revealed a causal association between unemployment and prostate cancer (OR: 3.07, 95%CI:1.12–8.42, P = 0.03). …”
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Temperature measurements with a temporal scanner: systematic review and meta-analysis by Ruzan Udumyan, Håkan Geijer, Georg Lohse, Ylva Nilsagård

“…A secondary outcome was sensitivity and specificity to detect fever. If tympanic thermometers were assessed in the same population as TAT, these results were recorded as well.Results 37 articles comprising 5026 participants were selected. …”
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Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…Ongoing research seeks to detect gene modifications in diverse cancer types, produce novel diagnostic tools, and develop treatments that particularly target these genetic changes. …”
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The MyJump App is a Valid Method of Assessing and Classifying Limb Symmetry During Recovery from Anterior Cruciate Ligament Reconstruction by Isaac Whiteley, Vasileios Sideris, Roula Kotsifaki, Enda King, Rod Whiteley

“… # Conclusion Where force plates are unavailable, the MyJump app is a valid and reliable substitute for criteria assessment of jump/hop height and reactive strength index in those recovering from ACL surgery using a 90% limb symmetry threshold. The minimum detectable changes vary by metric but are likely sufficiently accurate to detect clinical changes…”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…Dual-probe qPCR assays were developed to simultaneously detect mutant and wildtype alleles using differently labelled probes. …”
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Systematic review of functional magnetic resonance imaging (fMRI) applications in the preoperative planning and treatment assessment of brain tumors by Hamad Yahia Abu Mhanna, Ahmad Fairuz Omar, Yasmin Md Radzi, Ammar A. Oglat, Hanan Fawaz Akhdar, Haytham Al Ewaidat, Abdallah Almahmoud, Abdel-Baset Bani Yaseen, Laith Al Badarneh, Omar Alhamad, Laith Alhamad

“…We examined the foundational principles, practical implementations, and verification of fMRI via direct brain stimulation, with particular emphasis on its capacity to detect cerebral regions affected by tumors that are eloquent in nature. …”
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Combination of Gilbert's syndrome and gastrointestinal diseases by G. M. Dubrovina, O. K. Botvinyev, A. I. Kolotilina

“…The aim of review. To detect relation between Gilbert's syndrome (GS) and other diseases of a gastrointestinal tract (GIT).Key points. …”
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Reassessing Nutritional Supplementation Program: The Impact of Maternal Vitamin B12 Levels on Feto-Maternal Outcomes by Pranjali Dhume, Reshu Rawal, Ashish Vadhera, Ankur Shah, Madhusudan Dey, Sunil Chawla, Suyash Goel, Simran Gilhotra, Ankita Sharma

“…While folate deficiency has been acknowledged in not only the prevention of neural tube defects and other adverse pregnancy outcomes, the effects of low vit B12 status have not been well defined. …”
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The Potential Applications of Stem Cell Conditioned Medium Secretome in Knee Cartilage Regeneration: A Systematic Review by I Gusti Ngurah Wien Aryana, Febyan Febyan, Nyoman Gede Grenata Nanda Ustriyana

“…This review explores the application of MSCs and their secretome to address cartilage defects. Methods: This review was conducted based on PRISMA guidelines. …”
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Serum lipids mediate the association of per- and polyfluoroalkyl substances exposure and age-related macular degeneration. by Xiaodong Chen, Jiaqi Li, Ningda Xu, Xuewei Li, Jiarui Li, Qianwen Guo, Jia Zhang, Heng Miao, Lvzhen Huang

“…Four serum PFAS levels with high detective rates, including perfluorononanoic acid (PFNA), perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorohexane sulfonic acid (PFHxS) were examined. …”
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The pro-inflammatory cytokine Tumor Necrosis Factor alpha (TNF-α) in Diabetic Nephropathy by Alia KH Mahmoud, Muhammed Ahmed Abd El Moety, Amal Khalifa Ahmed, Samer A. El-Sawy

“…Furthermore, a variety of inflammatory chemicals, including pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-α). Objectives: is to detect the role of TNF-α as a pathogenic factor in diabetic nephropathy. …”
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Hyperkalemia or Not? A Diagnostic Pitfall in the Emergency Department by Frank-Peter Stephan, Florian N. Riede, Luca Ünlü, Gioele Capoferri, Tito Bosia, Axel Regeniter, Roland Bingisser, Christian H. Nickel

“…However, the frequency of factitious hyperkalemia, an artificially elevated potassium level in hyperkalemic ED patients, is unknown. This study aims to detect the rate of factitious hyperkalemia among patients with a potassium concentration of ≥5.0 mmol/l in an all-comer ED population. …”
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Resolving the electronic ground state of La3Ni2O7-δ films by Xiaolin Ren, Ronny Sutarto, Xianxin Wu, Jianfeng Zhang, Hai Huang, Tao Xiang, Jiangping Hu, Riccardo Comin, Xingjiang Zhou, Zhihai Zhu

“…Additionally, in La3Ni2O7-δ films, we detect a superlattice reflection (1/4, 1/4, L) at the Ni L absorption edge using resonant X-ray scattering measurements. …”
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Sustained slow-release TGF-β3 in a three-dimensional-printed titanium microporous scaffold composite system promotes ligament-to-bone healing by Liwei Zhu, Yuzhe Liu, Yifu Sun, Zhenjia Che, Youbin Li, Tengyue Liu, Xudong Li, Chengzhe Yang, Lanfeng Huang

“…Micro-CT results demonstrated that the complex promotes the osseointegration of titanium scaffolds in bone defects. Hard tissue sections showed that the new bone, ligament, and the titanium alloy scaffold system formed a closely integrated whole; the composite system provided suitable attachment points for ligament growth. …”
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Soluble fibres modulate dough rheology and gluten structure via hydrogen bond density and Flory-Huggins water interaction parameter by Stefano Renzetti, Lisa Lambertini, Helene C.M. Mocking-Bode, Ruud G.M. van der Sman

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X-Ray/Radio Quasiperiodic Pulsations Associated with Plasmoids in Solar Flare Current Sheets by Pankaj Kumar, Judith T. Karpen, Joel T. Dahlin

“…RHESSI X-ray images show double coronal sources (“looptop” and higher coronal sources) located at both ends of the flare current/plasma sheet. Moreover, we detect an additional transient faint X-ray source (6–12 keV) located between the double coronal sources, which is cospatial with multiple plasmoids in the flare current sheet. …”
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Analysis of the 2016 – 2025 fiscal budget of U.S. Centers for Disease Control and Prevention by Nana LIU, Lieyu HUANG, Yuan DANG, Zekai YU, Qianqiu LIU, Yan GUO

“…The budget for "Birth Defects, Developmental Disabilities, Disabilities and Health" remained at a relatively low level with minor fluctuations (US$ 0.100 billion to US$ 0.223 billion). …”
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