Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock by David A. C. Messerer, Stephanie Denk, Karl J. Föhr, Rebecca Halbgebauer, Christian K. Braun, Felix Hönes, Julia Harant, Michael Fauler, Manfred Frick, Benedikt L. Nußbaum, Peter Radermacher, Sebastian Hafner, Markus S. Huber-Lang

“…Polymorphonuclear granulocytes (PMN) play a crucial role in host defense. Physiologically, exposure of PMN to the complement activation product C5a results in a protective response against pathogens, whereas in the case of systemic inflammation, excessive C5a substantially impairs neutrophil functions. …”
Get full text

Fabrication and Characterization of Physical, Mechanical, and Wear Characteristics of AA7075/SiC Composites by Floating Die by Ameen Al Njjar, Kamar Mazloum, Amit Sata

“…The composite containing 5% SiC demonstrated superior properties, including a substantial increase in compressive strength (20.1%), weight reduction (13.7%), and a significant decrease in wear loss (83.28%), making it highly promising for aerospace, defense, and automotive sectors. Additionally, uniform failure models were observed in compression tests of composites fabricated using the floating die method. …”
Get full text

Flexural Performance of RC Continuous Beams Strengthening by CFRP with Grooves by Hanan Qassim, Mohammed Mashrei

“…The results are introduced in terms of ultimate load, ultimate deflection, ductility index and mode of failure. The test results showed that the EBROG strengthening method has highly effective in improving the ultimate load of strengthened beams. …”
Get full text

Microbial diversity and biogeography across gastrointestinal tracts of Takifugu pufferfish revealed by full-length 16S amplicon sequencing by Xingkun Jin, Yan Shi, Zhenlong Sun, Yaohui Wang, Zhe Zhao

“…Takifugu pufferfish, which are an example of species evolved through adaptive radiation, possess a GIT that is specialized for antipredator defense and gluttonous feeding behaviors, offering a unique model to explore the effects of GIT compartmentalization and host genetics on gut microbial communities. …”
Get full text

Study on the Full‐Cycle Stress Evolution Law and Reasonable Size of Isolated Coal Pillar by Xiao‐Xiang Wei, Qing‐Long Yun, Jing Wu, Xiao‐He Wang, Yin‐Wei Wang

“…The results show that the vertical stress and maximum principal stress increase correspondingly with the decrease of the protective coal pillar size under both stages, and the minimum value of the minimum principal stress occurs on the 8 m protective coal pillar; The values of the principal stress ratio and the principal stress deflection angle do not differ greatly in the protection of the coal pillar, and the fluctuation of the values is mainly concentrated in the vicinity of the back‐mining roadway; The second invariant of bias stress (J2) is mainly concentrated in the protective coal pillar near the side of the extraction zone, when the size of the protective coal pillar is reduced to 10 m, the J2 on the side of the extraction zone and the J2 on the side of the roadway are connected, and the whole protective coal pillar is under the influence of J2, which is basically the same as the damage pattern of the plastic zone; Based on the formula of limit balance theory to calculate the elastic core width of different sizes of protective coal pillars, and combined with the results of numerical simulation analysis, it finally concluded that the reasonable size of the protective coal pillar of this isolated island working face is 15 m.…”
Get full text

Numerical Method of Flexible Pavement considering Moisture and Stress Sensitivity of Subgrade Soils by Jue Li, Jianlong Zheng, Yongsheng Yao, Junhui Zhang, Junhui Peng

“…Results show that the surface deflection of the FEM model is similar to that of the actual pavement structure with the R2 of 98.44%. …”
Get full text

Tannins for food preservation and human health: A review of current knowledge by Yesim Ozogul, Yilmaz Ucar, Eskindir Endalew Tadesse, Nikheel Rathod, Piotr Kulawik, Monica Trif, Tuba Esatbeyoglu, Fatih Ozogul

“…The majority of species in the plant kingdom comprise tannins, which serve as a defense against predators. Tannins also play a role in regulating plant growth and development, while having a protective function against ultraviolet radiation. …”
Get full text

Comprehensive GC-MS Characterization and Histochemical Assessment of Various Parts of Three <i>Colchicum</i> Species from Bulgarian Flora by Ivayla Dincheva, Ilian Badjakov, Vasil Georgiev, Ivanka Semerdjieva, Radka Vrancheva, Ivan Ivanov, Atanas Pavlov

“…Organ-specific metabolic patterns revealed that corms and seeds are particularly rich in alkaloids, supporting their roles in chemical defense and survival during dormancy. Conversely, flowers, leaves, and capsules were enriched with energy-related and phenolic compounds, playing critical roles in reproduction and stress tolerance. …”
Get full text

The effect of cannabis-derived terpenes on alveolar macrophage function by Patrick M. Greiss, Patrick M. Greiss, Patrick M. Greiss, Jacquelyn D. Rich, Jacquelyn D. Rich, Jacquelyn D. Rich, Geoffrey A. McKay, Dao Nguyen, Dao Nguyen, Dao Nguyen, Dao Nguyen, Mark G. Lefsrud, David H. Eidelman, David H. Eidelman, David H. Eidelman, Carolyn J. Baglole, Carolyn J. Baglole, Carolyn J. Baglole, Carolyn J. Baglole, Carolyn J. Baglole

“…However, it is not known whether terpenes derived from cannabis alone or in combination with the cannabinoid ∆9-THC impacts the function of alveolar macrophages, a specialized pulmonary innate immune cell that is important in host defense against pathogens. Therefore, we investigated the immunomodulatory properties of two commercially-available cannabis terpene mixtures on the function of MH-S cells, a murine alveolar macrophage cell line. …”
Get full text

The Correspondence Between Sudden Commencements and Geomagnetically Induced Currents: Insights From New Zealand by A. W. Smith, C. J. Rodger, D. H. Mac Manus, C. Forsyth, I. J. Rae, M. P. Freeman, M. A. Clilverd, T. Petersen, M. Dalzell

“…We investigate the finding that the orientation of the strongest magnetic deflection is important: changes predominantly in the east‐west direction drive 36% stronger GICs. …”
Get full text

Temperature-dependent performance and constitutive modeling of additively manufactured Ti600 alloy by Tianhua Wen, Rui Fu, Sihang Xiao, Lei Zhang, Bo Song, Hongshuai Lei

“…Titanium alloys produced through selective laser melting (SLM) are increasingly utilized in aerospace, defense, and marine sectors due to their design flexibility and high-temperature capabilities. …”
Get full text

Deformation Monitoring Model of Buried Pipeline Mechanical Parts Based on the Distributed Optical Fiber Monitoring System by Bihua Shen, Xiangchao Wang, Mengya Sun, Wei Qian

“…However, distributed optical fibers could detect data between two points, making them more suitable for pipeline monitoring. …”
Get full text

The Effects of Disinfection Byproduct 2,6-Dichloro-1,4-benzoquinone on the Cyanobacterium <i>Microcystis aeruginosa</i>: From the Perspectives of Biochemistry and Non-Targeted Meta... by Tianqi Zhang, Zhaoyang Wang, Liang Wu, Chaonan Liu, Liang Meng, Fuxiang Tian, Meifang Hou, Haizhuan Lin, Jing Ye

“…The results show that 2,6-DCBQ inhibited the growth of <i>M. aeruginosa</i>, reduced its photosynthetic pigment and protein contents, increased the levels of reactive oxygen species, damaged the antioxidant defense system, and aggravated the cytomembrane. Meanwhile, 2,6-DCBQ stimulated the production and release of microcystin-LR (MC-LR) and altered the transcripts of genes associated with its synthesis (<i>mcyA</i>, <i>mcyD</i>) and transport (<i>mcyH</i>). …”
Get full text

Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasi... by Rigaud, Thierry, Balourdet, Aude, Bauer, Alexandre

“…Many trophically transmitted parasites with complex life cycles manipulate their intermediate host’s antipredatory defenses in ways facilitating their transmission to final host by predation. …”
Get full text

Review of Short-Wavelength Infrared Flip-Chip Bump Bonding Process Technology by Junhao Du, Xuewei Zhao, Jiale Su, Ben Li, Xiangliang Duan, Tianyu Dong, Hongxiao Lin, Yuhui Ren, Yuanhao Miao, Henry H. Radamson

“…These advancements stimulate new prospects across a wide array of fields including life sciences, medical diagnostics, defense, surveillance, security, free-space optics (FSO), thermography, agriculture, food inspection, and LiDAR applications. …”
Get full text

Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

“…This leads to diminished antioxidant defenses, increased oxidative damage, and exacerbated metabolic dysregulation and inflammation—key contributors to age-related diseases. …”
Get full text

Protective Effect of Melatonin on Acute Pancreatitis by Jolanta Jaworek, Joanna Szklarczyk, Andrzej K. Jaworek, Katarzyna Nawrot-Porąbka, Anna Leja-Szpak, Joanna Bonior, Michalina Kot

“…Specific receptors for melatonin have been detected in many gastrointestinal tissues including the pancreas. …”
Get full text

Identification and Characterization of the <i>ROP GTPase</i> Gene Family in Strawberry and the Positive Role of <i>FveROP4</i> in Fruit Resistance to Gray Mold by Shuai Zhao, Baode Zhu, Zhijun Zou, Yushan Zhai, Sufeng Liao, Ming Xu, Kunyang Li, Nasir Mehmood, Xiong Liao

“…ROP small GTPases function as signaling hubs that mediate various physiological processes, including plant defense. Their specific roles in strawberry resistance against gray mold remain uncharacterized. …”
Get full text

The Development of Drawdown Dolines and Subsidence Dolines with the Comparison of Their Bedrock Resistivities—A Case Study by Márton Veress

“…The piezometric surface is not deflecting below the subsidence dolines because resistivity differences are small between the bedrock below the doline and the bedrock of its environment. …”
Get full text

A non-linear procedure for the numerical analysis of crack development in beams failing in shear by P. Bernardi, R. Cerioni, E. Michelini, A. Sirico

“…Numerical results have been compared to experimental evidences not only in terms of global structural response (i.e. applied load vs. midspan deflection), but also in terms of crack pattern evolution and maximum crack widths.…”
Get full text