A Comparison of Two Dust Uplift Schemes within the Same General Circulation Model by Duncan Ackerley, Manoj M. Joshi, Eleanor J. Highwood, Claire L. Ryder, Mark A. J. Harrison, David N. Walters, Sean F. Milton, Jane Strachan

“…However, the representation of dust in GCMs is highly variable between modelling communities due to differences in the uplift schemes employed and the representation of the global circulation that subsequently leads to dust deflation. In this study two different uplift schemes are incorporated in the same GCM. …”
Get full text

Immunoglobulin M response in largemouth bass (Micropterus salmoides) following ranavirus infection by Zhenyu Huang, Naicheng Liu, Mingyang Xue, Chen Xu, Yuding Fan, Yan Meng, Nan Jiang, Yiqun Li, Wenzhi Liu, Yang He, Yong Zhou

“…Immunoglobulin M (IgM) and IgM+ B cells are key components of the humoral immune system, providing defense against pathogen invasion. While the role of IgM in the systemic and mucosal immune responses of fish to parasites and bacteria has been partially investigated, its function in viral infections remains underexplored. …”
Get full text

Investigation of genes expression of the JAK/STAT signalling pathway and AMPs in the presence of Borrelia spirochetes in Ixodes ricinus by Magdalena Szczotko, Sandra Antunes, Ana Domingos, Małgorzata Dmitryjuk

“…Direct antimicrobial defence occurs through the rapid synthesis of numerous antimicrobial agents including antimicrobial peptides (AMPs). …”
Get full text

THE IMPACT OF PROPRIOCEPTION DURING THE TRAINING PERIOD OF MALE JUNIOR II PLAYERS by Seciu Alex-Paul, Ene-Voiculescu Virgil, Popa Roxana-Nicoleta

“…Additionally, analyzing the study’s results will provide valuable insights into how proprioceptive training can be effectively incorporated into young athletes’ routines.In essence, sports competitions test every aspect of an athlete’s preparation, revealing opportunities in both offensive and defensive play in real time. A well-structured training program that includes proprioceptive exercises not only enhances joint stability and quick reflexes but also significantly reduces the risk of both acute and chronic injuries. …”
Get full text

Biological insights into alleviating heavy metal toxicity through the simultaneous supply of biochar biofilters derived from the Mikania micrantha and molybdenum nanoparticles by Muhammad Shoaib Rana, Hongyu Chen, Shiwen Deng, Muhammad Imran, Yousif Abdelrahman Yousif Abdellah, Wanting Li, Jiayu Lin, Jiaxi Li, Ruilong Wang

“…Additionally, this strategy not only preserved mesophyll cell structures and the membrane integrity, but also strengthened and activated the oxidative defense systems through the regulation of genetic expressions. …”
Get full text

Magnetic Resonance Visibility, Artifacts, and Overall Safety of the Self-Locating Peritoneal Dialysis Catheter with a Tungsten Tip by Maurizio Gallieni, Umberto G. Rossi, Massimo Tonolini, Andrea Ianniello, Roberta Miglio, Gianmarco Sabiu, Maurizio Cariati

“…The catheter showed no magnetic deflection, rotation, or movements during all MR sequences. …”
Get full text

Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease by Ana R. Pérez, Ana R. Pérez, Oscar A. Bottasso, Oscar A. Bottasso, Oscar A. Bottasso, Natalia E. Santucci, Natalia E. Santucci

“…Over time, disturbances in cytokine, hormone, and other compound production foster an unbalanced, detrimental defensive response. This complexity underscores the significant role of ligand-dependent NRs. …”
Get full text

Effects of R-Phase on Mechanical Responses of a Nickel-Titanium Endodontic Instrument: Structural Characterization and Finite Element Analysis by Leandro de Arruda Santos, Pedro Damas Resende, Maria Guiomar de Azevedo Bahia, Vicente Tadeu Lopes Buono

“…During bending, the fully R-phased instrument reached the lowest stress values; however, it also experienced the highest angular deflection when subjected to torsion. In summary, this simulation showed that NiTi endodontic instruments containing only R-phase in their microstructure would show higher flexibility without compromising their performance under torsion.…”
Get full text

Mechanical properties of new endodontic instruments: a comparative approach with different in vitro tests by Maya Feghali, Biraj Patel, Dina Adami, James Wealleans, Massimo Galli, Tugba Turk

“…On the contrary, statistically significant differences can be noted in all sized when evaluation torsional resistance using the deflection angle and cyclic fatigue, with “Diamond” instruments providing the best Results. …”
Get full text

Tear Film Proteome of Healthy Domestic Cats by Jéssica Fontes Veloso, Paula Elisa Brandão Guedes, Luciana Carvalho Lacerda, Juliano Oliveira Santana, Irma Yuliana Mora-Ocampo, Carlos Priminho Pirovani, Arianne Pontes Oriá, Alexandre Dias Munhoz, Renata Santiago Alberto Carlos

“…Forty peptides were detected in the analyzed protein fragments of 90 spots, with 16 proteins identified. …”
Get full text

Targeting lipid metabolism: novel insights and therapeutic advances in pancreatic cancer treatment by Yanyan Zhang, Zhichao Yang, Yuchen Liu, Jinjin Pei, Ruojie Li, Yanhui Yang

“…Moreover, lipid metabolism dysregulation within immune cells, particularly T cells, impairs immune surveillance and weakens the body’s defenses against cancer. Abnormal lipid metabolism also contributes to drug resistance in PC. …”
Get full text

Customized evaluation of special endurance and functionality for optimal health and performance in judo athletes by Valery Goloha, Pavol Bartik

“…Thirteen experienced judo athletes were tested using a dummy throw with a deflection for 4 minutes, with the number of throws and heart rate dynamics assessed during and after the exercise. …”
Get full text

Frk positively regulates innate antiviral immunity by phosphorylating TBK1 by Xiaomei Zhang, Ying You, Tingrong Xiong, Tingrong Xiong, Xiaokai Zhang, Haibo Wang, Jinxia Geng, Miao Wang, Yanyan Xu, Shanshan Gao, Shanshan Gao, Xiaoyan Wu, Yue Zheng, Xianhua Wen, Haoyu Yang, Yu Wang, Yu Wang, Xiaohua Wen, Congcong Zhao

“…Type I interferons (IFN-I) are crucial for the initial defense against viral infections. TBK1 serves as a key regulator in the production of IFN-I, with its phosphorylation being essential for the regulation of its activity. …”
Get full text

REFLECTIONS REGARDING THE WITNESS'S RIGHT AGAINST SELF-INCRIMINATION by Luminița CRIȘTIU-NINU, Cătălin-Nicolae MAGDALENA

“…The balance between the general interest of a fair conduct of the criminal proceedings and the rights of the „suspected″ witness has required and continues to require practical solutions from the judicial authorities, ensuring that the right to defense and the right to a fair trial are respected.…”
Get full text

Design and Performance Analysis of a TLET-Type Flexure Hinge by Ngoc Le Chau, Ngoc Thoai Tran, Thanh-Phong Dao

“…In order to permit a large deflection, three lamina emergent torsional flexure hinges are reconfigured to create a new triple LET-type flexure hinge (TLET) in this paper. …”
Get full text

Assessments of F16 Special Sensor Microwave Imager and Sounder Antenna Temperatures at Lower Atmospheric Sounding Channels by Banghua Yan, Fuzhong Weng

“…The main reflector of the Special Sensor Microwave Imager/Sounder (SSMIS) aboard the Defense Meteorological Satellite Program (DMSP) F-16 satellite emits variable radiation, and the SSMIS warm calibration load is intruded by direct and indirect solar radiation. …”
Get full text

Education as a Fundamental Element in Ensuring the National Security of the State by Vasilii A. Dadalko, Aleksandr G. Kostanyants, Gleb A. Neustroev

“…It forms qualified personnel capable of ensuring technological progress, economic stability and defense against external threats. The development of the education system should become a priority task of State policy, as it is through the education of literate, responsible and patriotic citizens that the long-term well-being and sustainable development of the country can be achieved.…”
Get full text

The role of interleukin-17 in inflammation-related cancers by Xingru Zhang, Xingru Zhang, Bangjie Li, Tian Lan, Tian Lan, Conner Chiari, Xiaoyang Ye, Kepeng Wang, Ju Chen

“…IL-17 is a highly versatile pro-inflammatory cytokine that plays a pivotal role in host defense, tissue repair, the pathogenesis of inflammatory diseases, and cancer progression. …”
Get full text

Redox Metabolism and Autonomic Regulation During Aging: Can Heart Rate Variability Be Used to Monitor Healthy Longevity? by Olha Yelisyeyeva, Danylo Kaminskyy, Marta Semen, Ilona Chelpanova, Khrystyna O. Semen

“…Excessive activation of free radical reactions accompanied by the inability of the antioxidant defense (AOD) mechanisms to control the flow of the reactive oxygen species (ROS) leads to the persistence of oxidative stress, hypoxia, impaired mitochondrial energy function and reduced ATP potential. …”
Get full text

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats by Lorenzo Di Cesare Mannelli, Daniele Bani, Andrea Bencini, Maria Luisa Brandi, Laura Calosi, Miriam Cantore, Anna Maria Carossino, Carla Ghelardini, Barbara Valtancoli, Paola Failli

“…In these conditions, the physiological defense against , superoxide dismutases (SOD) are decreased. …”
Get full text