Microcephaly protein ANKLE2 promotes Zika virus replication by Adam T. Fishburn, Cole J. Florio, Thomas N. Klaessens, Brian Prince, Neil A. B. Adia, Nicholas J. Lopez, Nitin Sai Beesabathuni, Sydney S. Becker, Liubov Cherkashchenko, Sophia T. Haggard Arcé, Vivian Hoang, Traci N. Shiu, R. Blake Richardson, Matthew J. Evans, Claudia Rückert, Priya S. Shah

“…Thus, ANKLE2 likely promotes orthoflavivirus replication by regulating membrane rearrangements that serve to accelerate viral genome replication and protect viral dsRNA from immune detection. Taken together with our previous results, our findings indicate that ZIKV and other orthoflaviviruses hijack ANKLE2 for a conserved role in replication, and this drives unique pathogenesis for ZIKV since ANKLE2 has essential roles in developing tissues.IMPORTANCEZIKV is a major concern due to its association with birth defects, including microcephaly. …”
Get full text

Construct validation of a complete postpartum health and well-being patient reported outcome measure: prospective cohort studyAJOG Global Reports at a Glance by Laura J. O'Byrne, BMBS, MSc, PhD, Gillian M. Maher, PhD, Jill M. Mitchell, MB, BCh, BAO, Ali S Khashan, PhD, Richard M. Greene, MB, BCh, BAO, John P. Browne, PhD, Fergus P. McCarthy, MB, BCh, BAO, PhD

“…Examining the tools’ ability to detect changes based on morbidity found no significant differences in PQoL, ICIQ-UI SF or pelvic pain scores between groups with and without maternal morbidity. …”
Get full text

Deteksi Covid-19 pada Citra Sinar-X Dada Menggunakan Deep Learning yang Efisien by Novanto Yudistira, Agus Wahyu Widodo, Bayu Rahayudi

“…The deep CNN model can detect accurately but tends to require large memory usage. …”
Get full text

Effect of Fireworks, Chinese New Year and the COVID-19 Lockdown on Air Pollution and Public Attitudes by Peter Brimblecombe, Yonghang Lai

“…Beijing, where restrictions were less stringent, showed some improvement in air quality, though this is more difficult to detect, even within the 5th Ring Road.…”
Get full text

Capacitance Measurements of Exocytosis From AII Amacrine Cells in Retinal Slices by Espen Hartveit, Margaret Veruki

“…Even in such cases, however, it can be possible to detect a depolarization-evoked increase in capacitance. …”
Get full text

Perceptions of orthodontically treated smile esthetics: a comparative evaluation of orthodontists, general dentists, and laypersons in Erbil city. by Isra Dilshad Rostum, Zana Omer

“…Laypersons could only detect variations in crown length, width, and angulation. …”
Get full text

Educação infantil e educação em direitos humanos: a construção de uma cultura de paz desde o nascimento by Joedson Brito dos Santos, Francisca Rodrigues Lopes, Fernanda de Jesus Santos

“… O presente artigo discute Educação Infantil e Educação em Direitos Humanos e tem como objetivo apresentar proposições relativas à defesa de que a educação em direitos humanos deve se configurar desde a educação infantil. …”
Get full text

Analysis of hematology quality control using six sigma metrics by Shreya Goel, Amit R. Nisal, Ankita Raj, Ravindra C. Nimbargi

“…In sigma metrics, errors identified are quantified as percentage errors or defects per million (DPM). It aims at improving the quality control (QC) process by forming an appropriate strategy. …”
Get full text

Thermal Changes in Guidewires Used During Endoscopic Retrograde Cholangiopancreatography During Electrical Conductance: An Ex-Vivo Safety Experiment by Rahul Karna, Nicholas Michael McDonald, Jacob Weiner, Théodon I. Netoff, Stuart K Amateau

“…Also, the Glidewire 0.018” and the Visiglide 0.025” produced visible sparks along their distal ends with defects in the insulation found later under microscopic evaluation. …”
Get full text

Does instruction through mother tongue impede students’ English proficiency? public skepticism on the instructional language policy in the state of Amhara by Melaku Gebremeske

“…Apart from lack of resource supply the defects in its formulation procedure have lingering effects on the realization of instructional language policy. …”
Get full text

Carnivore activity across landuse gradients in a Mexican biosphere reserve by Germar González, Siria Gámez, Nyeema C. Harris

“…In total, we detected 14 carnivores in the core zones, 10 in the buffer zone, and 9 on private land across the 4777 trap-night survey. …”
Get full text

The enigma of cancer polyploidy as deciphered by evolutionary cancer cell biology (ECCB) by Vladimir F. Niculescu, Eugenia R. Niculescu

“…Therefore, we investigate (i) functional polyploidies of healthy cells, including humans, mammals, and protists; (ii) dysfunctional polyploidies of cells with impaired HR and irreparable DNA-DSB defects; and (iii) the restoration of genome integrity through cyst-like and high-grade polyploidization events. …”
Get full text

Hydroacoustic sensing of seismic events during the Tajogaite volcanic eruption (La Palma, Spain) by Jesús Alcázar-Treviño, Guillermo Lara, Eduardo D. Suarez, Manuel Bou, Itahiza Domínguez, Susannah Buchan, Francisco Domínguez, Eugenio Fraile-Nuez

“…Our findings demonstrate that shallow-water hydro-acoustics can detect and estimate the magnitude of volcano-tectonic earthquakes in the studied scenario. …”
Get full text

Non-Destructive Testing of the Quality of Wooden Columns in Zeng Jingyi’s Ancient Wooden Structures by Jing Yang, Shaojie Wu, Yingcai Fang, Benhuan Xu, Zheng Wang

“…The CT scan findings align with the pilot nail test results, both accurately pinpointing the condition and precise locations of defects within the columns. The static mechanical performance tests substantiated the precision and dependability of the CT scanning, pilot nail testing, and stress wave analysis in evaluating the wooden columns’ quality. …”
Get full text

Rêver le paysage, se soucier du vivant : pour une recherche-fiction by Gilles Clément

“…Without denying what has been thought, the article tries to defend the importance of the hypothesis and the experimentation, which are at the origin of every landscape project and of every research in landscape. …”
Get full text

Survey on Knowledge, Use, and Diagnostic Applicability of Special Tests for Rotator Cuff Involvement in Clinical Practice by Steven W. Forbush, William D. Bandy, Gabrielle L. Back-Kremers, Mollie Renfroe, Haley F. Downey

“…Others have disagreed, reporting that special tests were able to accurately detect the presence of rotator cuff involvement. # Purpose The purpose of this study was to determine the knowledge, use, and perceived effectiveness of 15 selected special tests utilized to examine patients with possible rotator cuff dysfunction…”
Get full text

Recycled PVC content and particle size distribution effects on morphological and mechanical properties of expanded PVC layer for floorcoverings by Chaouch, Walid, Msahli, Slah

“…However, higher quantities lead to a substantial deterioration in the material’s mechanical properties, primarily due to the emergence of structural defects. To refine the amount of recycled PVC used specifically for this floorcovering application, an in-depth analysis was conducted by meticulously adjusting the particle size distribution (PSD) through a sequence of three distinct sieving processes. …”
Get full text

STAPHYLOCOCCAL INFECTION IN DOGS (DIAGNOSIS, TREATMENT AND PREVENTION) by V. B. Rudenko, P. A. Rudenko, S. G. Semushina, I. A. Pakhomova

“…Staphylococcal infection in dogs is an infectious disease caused primarily by staphylococcus virulent strains, characterized by various clinical forms, and it affects the dogs having defects in their immune system. Staphylococci produce a great number of pathogenicity factors (including toxins able to act independently). …”
Get full text

Recent advances in understanding and managing body dysmorphic disorder by David Mataix-Cols, Lorena Fernández de la Cruz, Georgina Krebs

“…Body dysmorphic disorder (BDD) is a relatively common and disabling psychiatric disorder characterised by excessive and persistent preoccupation with perceived defects or flaws in one's appearance, which are unnoticeable to others, and associated repetitive behaviours (eg, mirror checking). …”
Get full text

Application of the Perme Score to assess mobility in patients with COVID-19 in inpatient units by Milena Siciliano Nascimento, Claudia Talerman, Raquel A. C. Eid, Simone Brandi, Luana L.S. Gentil, Fernanda M. Semeraro, Fabiano B. Targa

“…# Objective To evaluate the ability of the Perme Score to detect changes in the level of mobility of patients with COVID-19 outside the intensive care unit…”
Get full text