T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy by Linghua Wang, Siqing Fu, Aung Naing, Funda Meric-Bernstam, Carl Morrison, Joud Hajjar, Mingxuan Xu, Anas Alshawa, Bettzy Stephen, Ying Yuan, Jordi Rodon Ahnert, Abdulrazzak Zarifa, Shrutii Sarda, Timothy Looney, Sapna P Patel, Geoffrey M Lowman, Dzifa Yawa Duose, Jeffrey M Conroy, Evan Kwiatkowski

“…We employed multiplex PCR to create amplicons spanning the three beta chain complementarity-determining regions (CDR) regions to enable detection of polymorphism within the germline-encoded framework and CDR1 and CDR2 regions in addition to CDR3 profiling. …”
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Physiological and multi-omics analysis revealed the mechanism of arbuscular mycorrhizal fungi to cadmium toxicity in green onion by Kunhao Xie, Yixuan Chen, Xiaoqin Wang, Xiaoya Zhou, Yizhe Cheng, Xianchang Yu, Jun Wang, Mintao Sun, Yansu Li, Chaoxing He

“…Thus, AMF enhance Cd tolerance in green onions by sequestering Cd in roots, restricting its translocation, modulating antioxidant defenses and inducing the expression of genes involved in the phenylpropanoid biosynthesis and phenylalanine metabolism pathways. …”
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The effect of prednisolone ingestion and acute exercise on lipocalin-2 and its variants in young men: a pilot randomised crossover study by Carlie Bauer, Rhiannon K. Patten, Qiyang Sun, Haoyun Li, Daniels Konja, Mary Woessner, Xuzhu Lin, Andrew Garnham, David L. Hare, Peter R. Ebeling, Marc Sim, Joshua R. Lewis, Yu Wang, Lewan Parker, Itamar Levinger

“…A main effect, increase in LCN2 was detected for prednisolone ingestion (overall treatment effect p = 0.001), but not LCN2 variants (all p > 0.05). …”
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Interaction between walkability and fine particulate matter on ischemic heart disease: A prospective cohort study in China by Jiayun Zhang, Peng Shen, Yixing Wang, Zihan Li, Lisha Xu, Jie Qiu, Jingjing Hu, Zongming Yang, Yonghao Wu, Zhanghang Zhu, Hongbo Lin, Zhiqin Jiang, Liming Shui, Mengling Tang, Mingjuan Jin, Feng Tong, Kun Chen, Jianbing Wang

“…Walkability and PM2.5 were positively correlated (rs = 0.12, P < 0.001), and a multiplicative interaction was detected (Pinteraction = 0.019). Conclusion: Walkability was inversely associated with risk of IHD, whereas exposure to PM2.5 was positively associated with IHD. …”
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On the tracks of an uninvited guest, the Asian tiger mosquito, Aedes albopictus in Cyprus by Riccardo Piccinno, Giulia Fiorenza, Marlen Ines Vasquez, Jeremy Bouyer, Gregoris Notarides, Ludvik Marcus Gomulski, Soteris Meletiou, Mustafa Akiner, Antonios Michaelakis, Federico Forneris, Giovanni Maga, Giuliano Gasperi, Anna Rodolfa Malacrida

“…An ongoing mosquito dispersal within the Limassol district was detected, suggesting the presence of established, hidden adventive populations. …”
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Feasibility study to assess the delivery of a lifestyle intervention (TreatWELL) for patients with colorectal cancer undergoing potentially curative treatment by Annie S Anderson, Ronan E O’Carroll, Martine Stead, Robert J C Steele, Mary Wells, Maureen Macleod, Anna Campbell, Jacqui A Sugden, Jackie Rodger, Jennifer McKell

“…Physical activity data showed a positive trend towards increased activity overall, but no other changes in secondary outcomes were detected.Conclusions To make this intervention feasible for testing as a full trial, further research is required on (a) recruitment optimisation, (b) appropriate assessment tools, (c) protocols for phase 2 and 3, which can build in flexibility and (d) ways for NHS staff to facilitate the programme.Trial registration number ISRCTN52345929; Post-results.…”
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Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination by Katja Uršič Valentinuzzi, Katja Uršič Valentinuzzi, Urška Kamenšek, Urška Kamenšek, Simona Kranjc Brezar, Chloe Heranney, Chloe Heranney, Tilen Komel, Tilen Komel, Simon Buček, Simon Buček, Maja Čemažar, Maja Čemažar, Gregor Serša, Gregor Serša

“…Variances in the antitumor (immune) response were also detected based on the chemotherapeutic drug used in ECT. …”
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The influence of post-processing methods and frequency bands on rs-fMRI: An example of electroacupuncture at Zusanli (ST36) by YingJie Kang, YiLei Chen, ZhiGang Gong, YanWen Huang, Hui Wang, Jiling Huang, SongHua Zhan, YiJing Li, WenLi Tan

“…PerAF was the most sensitive method for detecting LFO amplitude changes and revealed changes in white matter. …”
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The Autoimmune Profiles in the Etiopathogenesis of Granulomatous Lobular Mastitis by Lu Xie, Jiamei Feng, Qingqian Gao, Wenchao Qu, Shijun Shao, Jiaye Sun, Xueqing Wu, Hua Wan

“…Immunohistochemical staining (10 GLM, 10 FA normal tissues) detected IL-1β, IL-6, CD86 and CD206, and immunofluorescence (3 GLM, 3 FA normal tissues) evaluated CD86 and CD206 expression. …”
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Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

“…Conclusions Alterations in subclass-specific IgG N-glycosylation represent promising biomarkers for the detection and monitoring of GC progression, potentially influenced by cytokine-driven inflammation. …”
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The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers by Terkimbi Dominic Swase, Ilemobayo Victor Fasogbon, Ifie Josiah Eseoghene, Ekom Monday Etukudo, Solomon Adomi Mbina, Chebet Joan, Reuben Samson Dangana, Chinyere Anyanwu, Comfort Danchal Vandu, A. B Agbaje, Tijjani Salihu Shinkafi, Ibrahim Babangida Abubarkar, Patrick Maduabuchi Aja

“…The expression of cervical cancer biomarker such as p16INK4a and Ki-67 emphasized target screening and early detection strategy in high-risk population. However, there was no direct impact of HPV/HIV co-infection reported on these biomarkers and required to be studied more especially in people living with HIV.…”
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Earth–lunar thermal effect on the temperature stability of TianQin telescope and the suppression methods by Wenbo Chang, Yuxiang Wang, Wenhai Tan, Guanhua Wu, Houyuan Chen, Wei Li, Zizheng Li, Fan Zhu, Zhu Li, Xuefeng Zhang, Shanqing Yang

“…TianQin is a geocentric space-based gravitational wave detection mission, it will confront a more complex and variable orbital thermal environment compared to heliocentric orbit missions like LISA. …”
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Wnt signaling as a translational target in rheumatoid and psoriatic arthritis by Gloria Riitano, Francesca Spinelli, Valeria Manganelli, Daniela Caissutti, Antonella Capozzi, Cristina Garufi, Tina Garofalo, Roberta Misasi, Maurizio Sorice, Fabrizio Conti, Agostina Longo, Cristiano Alessandri

“…Values were correlated with CTX-1, detected by ELISA, and with disease activity indices: Disease Activity Score on 28 joints (DAS28-CRP) for RA and the Disease Activity in Psoriatic Arthritis (DAPSA) score for PsA. …”
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Marcio POCHMANN. Nova Classe Média? O trabalho na base da pirâmide social brasileira. São Paulo: Boitempo, 2012. 123 páginas. by Vinicius Lobo

“…Em terceiro lugar, gostaria então de ressaltar que sua tentativa de aprofundar a reflexão sobre a recente mobilidade social brasileira termina por oferecer uma nova interpretação do fenômeno, a de que o grosso da população emergente não se encaixa em critérios objetivos que possam ser identificados como de classe média. Defende que a população emergente na verdade associa-se às características gerais das classes populares, que por elevar sua renda, aumentam imediatamente seu padrão de consumo. …”
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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“…The imperative for robust preparedness, encompassing early detection, rapid response mechanisms, and efficient resource allocation, forms the cornerstone of epidemic management. …”
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ECONOMIC ASPECT OF CRIMINAL LAW COUNTERACTION TO JUSTIFICATION OF ARMED AGGRESSION AGAINST UKRAINE: RISKS FOR THE STATE BUDGET IN THE LIGHT OF THE PRACTICE OF THE EUROPEAN COURT OF... by Andrii Lapkin, Daryna Yevtieieva, Daria Kukovynets

“…The empirical basis of the study was as follows: (1) statistical data on Ukraine's participation as a defendant in the ECHR and the expenses incurred by it for the compensation of damages in 2019-2023; (2) approximately 900 verdicts of Ukrainian courts under Article 4362 of the Criminal Code; (3) the survey results of 4015 law enforcement officers of Ukraine on countering the glorification of the Russian armed aggression in Ukraine; (4) the survey results of 16 Ukrainian judges on countering the glorification of the Russian armed aggression in Ukraine; (5) 46 ECHR judgments. …”
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Using the WHO building blocks to examine cross-border public health surveillance in MENA by Laura Buback, Shayanne Martin, Esbeydy Pardo, Farah Massoud, Jesus Formigo, Atousa Bonyani, Noha H. Farag, Zayid K. Almayahi, Kenta Ishii, Susie Welty, Dana Schneider

“…Public health surveillance, crucial for detecting and responding to infectious disease outbreaks, is key to building health system resilience. …”
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HIV-1 resistance mutations and genetic diversity among children failing antiretroviral treatment in five healthcare facilities in Benin, West Africa. by Edwige Hermione Dagba Gbessin, Edmond Tchiakpe, René Kpemahouton Keke, Nicole Vidal, Michel Kiréopori Gomgnimbou, Haziz Sina, Euloge Senan Adjou, Aldric Afangnihoun, Moussa Bachabi, Akadiri Yessoufou, Abdoul-Salam Ouedraogo, Lamine Baba-Moussa

“…Resistance testing was successful among (37/47; 78.72%) children, resistance mutations were detected in (32/37; 86.48%) children, and (29/32; 90.62%) had at least one surveillance drug resistance mutation. …”
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Ilaser Submucous Destruction in the Treatment of Hemorrhoids by S. A. Frolov, D. V. Vyshegorodtsev, A. M. Kuzminov, Yu. L. Trubacheva, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. N. Ryndin, A. A. Anarbaeva

“…In terms of up to 6 months, there were no signs of a return of the disease in any case (hemorrhoidal prolapse and blood discharge). The detected hemorrhoids before the operation, a month after the operation, were not visualized, which persisted after 6 months. …”
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Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1 by Hong Zhou, Jiaxin Zhou, ShanShan Liu, Jing Niu, Jinghua Pan, Ruiman Li

“…We assessed the antioxidant capacity of hDMSCs in both groups by detecting relevant indicators. Furthermore, differentially expressed miRNAs in hDMSCs were analyzed through miRNA sequencing. …”
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