Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

“…The alterations in endogenous metabolites were detected by untargeted metabolomics, and their potential correlation with intestinal flora was then examined utilizing Spearman correlation analysis. …”
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Long-Term Monitoring of Liver Fibrosis and Steatosis in Patients with Chronic Hepatitis C after Achieving a Sustained Virologic Response to Antiviral Therapy by K. R. Dudina, P. A. Belyy, I. V. Maev, N. Kh. Safiullina, E. A. Klimova, S. A. Shutko, O. O. Znoyko, N.  D. Yushchuk

“…At the same time, regression of liver steatosis was detected only in 31 % of the patient, worsening of the results was in 23 % (26 % of them had the appearance of steatosis (S) of the liver of 1–3 degrees in persons with no fatty liver before the start of AVT). …”
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A Framework for Analyzing Absorptive Capacity Using Social Network Analysis (Case Study: Sharif University Innovation Ecosystem) by Mahdi Mohammadi, Mahdi Elyasi, Azadeh Savehshemshaki

“…As the absorptive capacity of technological fields is conducive to their innovative performance, detecting and fostering the knowledge flow between such fields ways is essential to develop the innovative platform of innovation clusters, which, in turn, aims at investigating the current situation in terms of the dimensions of absorptive capacity, namely acquisition, adaptation, transfer, and exploitation in the innovation cluster's scope and its external environment. …”
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ASSESSMENT OF THE REGION'S INVESTMENT ENVIRONMENT AND POLICY INSTRUMENTS FOR THE IMPLEMENTATION OF ITS INVESTMENT POTENTIAL IN WARTIME by Ruslan Boiko, Roman Martsenyuk, Arsen Protsykevych

“…It is substantiated that effective instruments of regional investment policy in the context of critical instability are: military risk insurance and diversification; use of concession agreements; private and public investments in the defence industry and critical infrastructure industries/sectors (energy, transport and logistics, medicine and pharmaceuticals, natural resources); support for innovative and technological startups in the areas of security, the real economy and infrastructure; stimulation of investments in human resources; support for investments in business projects of demobilised persons, war veterans and other combatants; encouragement of investments in the development of export potential to maintain the country's financial security.…”
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Klasifikasi Alzheimer Berdasarkan Data Citra MRI Otak Menggunakan Fcm Dan Anfis by Nilna Almumtazah, Muhammad Sahrul Kiromi, Nurissaidah Ulinnuha

“…This study intends to prevent Alzheimer's instances by performing early detection, lowering the likelihood that Alzheimer's patients would pass away. …”
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Symptoms of dwarf elm (Ulmus pumila L.) health condition in the Left-bank Ukraine by Valentyna L. Meshkova, Olena A. Kuznetsova, Volodymyr P. Turenko

“…The study aimed to search the relations between the distribution of visually detectable symptoms of U. pumila weakening and tree groups with apparent signs of bacterial wetwood and Dutch elm disease. …”
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Sequence-based GWAS in 180,000 German Holstein cattle reveals new candidate variants for milk production traits by Ana-Marija Križanac, Christian Reimer, Johannes Heise, Zengting Liu, Jennie E. Pryce, Jörn Bennewitz, Georg Thaller, Clemens Falker-Gieske, Jens Tetens

“…Conclusions Our findings proved the power of large samples and sequence-based GWAS in detecting new association signals. In order to fully exploit the power of GWAS, one should aim at very large samples combined with whole-genome sequence data. …”
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Estimating the Prevalence of Schizophrenia in the General Population of Japan Using an Artificial Neural Network–Based Schizophrenia Classifier: Web-Based Cross-Sectional Survey by Pichsinee Choomung, Yupeng He, Masaaki Matsunaga, Kenji Sakuma, Taro Kishi, Yuanying Li, Shinichi Tanihara, Nakao Iwata, Atsuhiko Ota

“…The crude prevalence of schizophrenia was calculated through the proportion of positive cases detected by the SZ classifier. The crude estimate was further refined by excluding false-positive cases and including false-negative cases to determine the actual prevalence of schizophrenia. …”
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Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease by Waimao Gao, Guang Yang, Xinjuan Liu, Kaifan Hu, Jie Pan, Xingyu Wang, Yan Zhao, Ying Xu

“…The protein-protein interaction (PPI) network was constructed and clusters were obtained using the Molecular Complex Detection (MCODE) and the Cytohubba plugins. Further, molecular docking study was performed for these core targets. …”
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GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…The changes in angiogenesis markers, autophagy markers, and eNOS levels were detected using qPCR and Western blotting. 3-MA was used to assess the role of autophagy in the activation of eNOS mediated by AST and its subsequent angiogenic effects.Results: GelMA@LNP/AST significantly promoted blood flow recovery in mice with hind limb ischemia. …”
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Proinflammatory Tear Cytokines in Human Adenoviral Keratoconjunctivitis and Clinical Eye Severity by Santacruz Valdés C, Ponce-Rosas ER, Jimenez-Martinez MC

“…In the less severely affected eyes, inflammatory response, conjunctival hyperemia, and conjunctival hemorrhages were significantly correlated with IL-12 and TNF-a, and ocular discharge was significantly correlated with all tear cytokines. IL-10 was detected in both eyes, suggesting a possible regulatory counterbalance.Discussion: This study offers novel insights into the pathophysiology of human adenoviral keratoconjunctivitis and its association with clinical data.Plain language summary: Despite the clinical significance of adenoviral keratoconjunctivitis, most studies have concentrated on defining its genotype. …”
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Biochemical blood parameters in platinum fox females and males in ontogenesis by I. I. Okulova, Yu. A. Berezina, A. S. Syutkina, I. A. Plotnikov, O. Yu. Bespyatykh, I. A. Domsky

“…Sexual differences in the alkaline phosphatase levels were detected in 1.5-month-old kits: alkaline phosphatase levels were higher by 21.05% in males than in females. …”
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Quality Control of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles by Krishnan I, Ng CY, Kee LT, Ng MH, Law JX, Thangarajah T, Zainuddin AA, Mahmood Z, Rajamanickam S, Subramani B, Lokanathan Y

“…Qualitatively, EVs-positive markers (CD63 and TSG101) and intact bilipid membrane vesicles were detected in all the sEV preparations. Quantitatively, the protein and particle concentrations revealed that all the sEV preparations were “impure” with < 1.5 × 109 particles/μg protein. …”
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STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

“…TLS formation in ADU S-100-treated mice was associated with the development of a highly oligoclonal TIL repertoire enriched in expanded T cell clonotypes unique to the TME and not detected in the periphery.Conclusions Our data support the premise that i.t. delivery of low-dose STING agonist promotes VN and a proinflammatory TME supportive of TLS formation, enrichment in the TIL repertoire and tumor growth control.…”
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Biomarkers of gastric atrophy at stomach cancer by A. V. Belkovets, S. A. Kurilovich., Yu. I. Ragino, L. V. Scherbakova, O. B. Cheremisina, N. V. Cherdyntseva, N. A. Andryushina, M. I. Voyevoda

“…Significantly lower PGI scores were detected in SC patients with histologically verified atrophy. …”
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Chronic lower back pain among occupational workers: effect of relaxation technique on quality of working life, pain and disability level with nurse-led intervention by Nabila ELSayed Sabola, Kamal Wifaq, Musaad M. Alruwaili, Rasha Kamal Mohamed Sweelam, Sabah Hassan El-Amrosy, Amal Yousef Abdelwahed

“…Additionally, occupational health nurses’ roles in the early detection and referral of LBP patients in diverse industrial settings should be strengthened.…”
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Vix (Côte-d’Or) et l’émergence des principautés celtiques : l’hypothèse portuaire et le concept de port of trade by Bruno Chaume

“…Moreover, geophysical surveys carried out by the German Archaeological Institute (DAI) suggest that the defensive system was extended towards the right bank of the Seine river, to enclose a section of the river several hundred metres long and that it included a palisade enclosure, in whose centre a magnetometric survey revealed a large apsidal building which may be characteristic of a princely seat. …”
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Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016&ndash;... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Cuixin Qiang,1,&ast; Xiaoxuan Liu,1,&ast; Pu Qin,1 Hainan Wen,2 Zhirong Li,1 Jing Yang,1 Yanan Niu,1 Weigang Wang,1 Zirou Ouyang,1 Min Zhao,1 Jiayiren Li,1 Yulian Zhang,1 Jianhong Zhao1 1The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianhong Zhao, The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China, Tel +86 0311 66002711, Email zhaojh_2002@hebmu.edu.cnPurpose: To analyze the clinical distribution and antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) isolated from blood specimens in 75 hospitals in Hebei Province from 2016 to 2021 to aid in the rational selection of antimicrobial drugs.Patients and Methods: WHONET 5.6 and SPSS 24.0 were used to retrospectively analyze clinical distribution characteristics and variations in drug-resistance.Results: Between 2016 and 2021, 2208 P. aeruginosa strains were detected in blood specimens from Hebei Province. The median age of the patients with isolated P. aeruginosa was 63 years, with a male-to-female ratio of 2.1:1. …”
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Segmentasi Citra Wajah dengan Implementasi Adaptif Threshold- Integral Image by Maryam Ummul Habibah, Muchamad Kurniawan

“…Abstract Face segmentation is an important in digital image processing to find out the object's face in the image before detecting facial expressions. Adaptive Threshold - Integral Image is a pixel-based segmentation technique, which is local thresholding. …”
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Rancang Bangun Alat Pengenal Finger Vein Menggunakan Raspberry Pi dengan Metode Convolutional Neural Network (CNN) by Barlian Henryranu Prasetio, Jevandika, Dahnial Syauqy

“…In this way, users can feel uncomfortable and the risk of spreading viruses or bacteria is very high, also the detection accuracy can be affected by factors such as sweaty and dry skin and skin distortion. …”
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