Klasifikasi Alzheimer Berdasarkan Data Citra MRI Otak Menggunakan Fcm Dan Anfis by Nilna Almumtazah, Muhammad Sahrul Kiromi, Nurissaidah Ulinnuha

“…This study intends to prevent Alzheimer's instances by performing early detection, lowering the likelihood that Alzheimer's patients would pass away. …”
Get full text

Sequence-based GWAS in 180,000 German Holstein cattle reveals new candidate variants for milk production traits by Ana-Marija Križanac, Christian Reimer, Johannes Heise, Zengting Liu, Jennie E. Pryce, Jörn Bennewitz, Georg Thaller, Clemens Falker-Gieske, Jens Tetens

“…Conclusions Our findings proved the power of large samples and sequence-based GWAS in detecting new association signals. In order to fully exploit the power of GWAS, one should aim at very large samples combined with whole-genome sequence data. …”
Get full text

Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease by Waimao Gao, Guang Yang, Xinjuan Liu, Kaifan Hu, Jie Pan, Xingyu Wang, Yan Zhao, Ying Xu

“…The protein-protein interaction (PPI) network was constructed and clusters were obtained using the Molecular Complex Detection (MCODE) and the Cytohubba plugins. Further, molecular docking study was performed for these core targets. …”
Get full text

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia by Lai L, Wu H, Peng L, Zhang Z, Wu X, Zheng S, Su Z, Chu H

“…The changes in angiogenesis markers, autophagy markers, and eNOS levels were detected using qPCR and Western blotting. 3-MA was used to assess the role of autophagy in the activation of eNOS mediated by AST and its subsequent angiogenic effects.Results: GelMA@LNP/AST significantly promoted blood flow recovery in mice with hind limb ischemia. …”
Get full text

Proinflammatory Tear Cytokines in Human Adenoviral Keratoconjunctivitis and Clinical Eye Severity by Santacruz Valdés C, Ponce-Rosas ER, Jimenez-Martinez MC

“…In the less severely affected eyes, inflammatory response, conjunctival hyperemia, and conjunctival hemorrhages were significantly correlated with IL-12 and TNF-a, and ocular discharge was significantly correlated with all tear cytokines. IL-10 was detected in both eyes, suggesting a possible regulatory counterbalance.Discussion: This study offers novel insights into the pathophysiology of human adenoviral keratoconjunctivitis and its association with clinical data.Plain language summary: Despite the clinical significance of adenoviral keratoconjunctivitis, most studies have concentrated on defining its genotype. …”
Get full text

Quality Control of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles by Krishnan I, Ng CY, Kee LT, Ng MH, Law JX, Thangarajah T, Zainuddin AA, Mahmood Z, Rajamanickam S, Subramani B, Lokanathan Y

“…Qualitatively, EVs-positive markers (CD63 and TSG101) and intact bilipid membrane vesicles were detected in all the sEV preparations. Quantitatively, the protein and particle concentrations revealed that all the sEV preparations were “impure” with < 1.5 × 109 particles/μg protein. …”
Get full text

STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

“…TLS formation in ADU S-100-treated mice was associated with the development of a highly oligoclonal TIL repertoire enriched in expanded T cell clonotypes unique to the TME and not detected in the periphery.Conclusions Our data support the premise that i.t. delivery of low-dose STING agonist promotes VN and a proinflammatory TME supportive of TLS formation, enrichment in the TIL repertoire and tumor growth control.…”
Get full text

Biomarkers of gastric atrophy at stomach cancer by A. V. Belkovets, S. A. Kurilovich., Yu. I. Ragino, L. V. Scherbakova, O. B. Cheremisina, N. V. Cherdyntseva, N. A. Andryushina, M. I. Voyevoda

“…Significantly lower PGI scores were detected in SC patients with histologically verified atrophy. …”
Get full text

Chronic lower back pain among occupational workers: effect of relaxation technique on quality of working life, pain and disability level with nurse-led intervention by Nabila ELSayed Sabola, Kamal Wifaq, Musaad M. Alruwaili, Rasha Kamal Mohamed Sweelam, Sabah Hassan El-Amrosy, Amal Yousef Abdelwahed

“…Additionally, occupational health nurses’ roles in the early detection and referral of LBP patients in diverse industrial settings should be strengthened.…”
Get full text

Multicenter Surveillance of Pseudomonas aeruginosa Isolates From Blood: Clinical Distribution Characteristics and Antibiotic Resistance Trends in Hebei Province, China (2016&ndash;... by Qiang C, Liu X, Qin P, Wen H, Li Z, Yang J, Niu Y, Wang W, Ouyang Z, Zhao M, Li J, Zhang Y, Zhao J

“…Cuixin Qiang,1,&ast; Xiaoxuan Liu,1,&ast; Pu Qin,1 Hainan Wen,2 Zhirong Li,1 Jing Yang,1 Yanan Niu,1 Weigang Wang,1 Zirou Ouyang,1 Min Zhao,1 Jiayiren Li,1 Yulian Zhang,1 Jianhong Zhao1 1The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Chengde Medical University, Chengde, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianhong Zhao, The Second Hospital of Hebei Medical University, Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, Hebei, People’s Republic of China, Tel +86 0311 66002711, Email zhaojh_2002@hebmu.edu.cnPurpose: To analyze the clinical distribution and antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) isolated from blood specimens in 75 hospitals in Hebei Province from 2016 to 2021 to aid in the rational selection of antimicrobial drugs.Patients and Methods: WHONET 5.6 and SPSS 24.0 were used to retrospectively analyze clinical distribution characteristics and variations in drug-resistance.Results: Between 2016 and 2021, 2208 P. aeruginosa strains were detected in blood specimens from Hebei Province. The median age of the patients with isolated P. aeruginosa was 63 years, with a male-to-female ratio of 2.1:1. …”
Get full text

Segmentasi Citra Wajah dengan Implementasi Adaptif Threshold- Integral Image by Maryam Ummul Habibah, Muchamad Kurniawan

“…Abstract Face segmentation is an important in digital image processing to find out the object's face in the image before detecting facial expressions. Adaptive Threshold - Integral Image is a pixel-based segmentation technique, which is local thresholding. …”
Get full text

Rancang Bangun Alat Pengenal Finger Vein Menggunakan Raspberry Pi dengan Metode Convolutional Neural Network (CNN) by Barlian Henryranu Prasetio, Jevandika, Dahnial Syauqy

“…In this way, users can feel uncomfortable and the risk of spreading viruses or bacteria is very high, also the detection accuracy can be affected by factors such as sweaty and dry skin and skin distortion. …”
Get full text

Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities by Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo

“…Medical imaging is critical in modern healthcare for accurately detecting and diagnosing various medical conditions. …”
Get full text

Surfaces environmental monitoring of SARS-CoV-2: Loop mediated isothermal amplification (LAMP) and droplet digital PCR (ddPCR) in comparison with standard Reverse-Transcription qua... by Simona Spiteri, Irene Salamon, Luna Girolamini, Maria Rosaria Pascale, Federica Marino, Carlo Derelitto, Laura Caligaris, Simone Paghera, Manuela Ferracin, Sandra Cristino

“…The results obtained using the QIAmp kit, suggested that the N2 target is more stable in the environment and could be most suitable for the virus environmental detection. The percentage of positive samples was similar among the techniques (26% for RT-LAMP, 36% for ddPCR and 23% for RT-qPCR). …”
Get full text

Effects of shrinkage, temperature and the degree of connection (N/N f) on the behavior of steel-concrete composite beams by Halima Aouad, Nacer Rahal, Houda Beghdad, Mohamed Sadoun, Abdelaziz Souici, Sara Zatir, Khaled Benmahdi

Get full text

Sistem Identifikasi Pembicara Berbahasa Indonesia Menggunakan X-Vector Embedding by Alim Misbullah, Muhammad Saifullah Sani, Husaini, Laina Farsiah, Zahnur, Kikye Martiwi Sukiakhy

“…Untuk membangun model, fitur-fitur diekstrak dengan menggunakan MFCC, dihitung voice activity detection (VAD), dilakukan augmentasi dan normalisasi fitur menggunakan cepstral mean and variance normalization (CMVN) serta dilakukan filtering. …”
Get full text

Prevalence of Helicobacter pylori infection and its Associated Risk Factors among symptomatic Residents of Sulaimani city, Kurdistan region, Iraq, 2020 by Seerwan Hama Rashid Ali, Sabiha Sharif Salih, Taib Ahmed Hama Sour, Goran Mohammad Raouf, Araz Latif Rahim

“…In conclusions the rate of helicobacter pylori infection in our study is 54.9% among the symptomatic patients, and the overall incidence of H. pylori UBT and Giemsa stain detection rate were 73.4 and 26.6% respectively.   …”
Get full text

Histological chorioamnionitis and its predictors among mothers with premature rupture of membranes delivering at tertiary hospitals in Uganda: a multicenter cross-sectional study by Ibrahim Abdi Abdinasir, Marie Pascaline Sabine Ishimwe, Maxwell Okello, Paul Byaruhanga, Ralph Samson Enyamitoit, Theoneste Hakizimana

“…These findings highlight the critical need for early detection and management of HCA in mothers with PROM, particularly in resource-limited settings. …”
Get full text

The effect of bacterial overgrowth syndrome and bacterial translocation on the course of liver cirrhosis by M. S. Zharkova, M. V. Mayevskaya, V. T. Ivashkin

“…Among patients with tense ascitis (n=16) bacterial DNA in ascitic fluid was detected in 9 cases (56,3%). Ascitis, resistant to diuretic therapy was more frequent in patients with bacterial translocation (66,7%) in comparison to patients without it (14,3%) [OR 4,667; 95%CI: 0,717–30,353; р=0,036]. …”
Get full text

Optimasi Fuzzy C-Means dan K-Means Menggunakan Algoritma Genetika untuk Pengklasteran Dataset Diabetic Retinopathy by Muhammad Ezar Al Rivan, Steven Steven, William Tanzil

“…Retina disorder can be known from data extracted from eye image. Early detection conduct using clustering. These methods are Fuzzy C-Means and K-Means. …”
Get full text