Deep learning improves physician accuracy in the comprehensive detection of abnormalities on chest X-rays by Pamela G. Anderson, Hannah Tarder-Stoll, Mehmet Alpaslan, Nora Keathley, David L. Levin, Srivas Venkatesh, Elliot Bartel, Serge Sicular, Scott Howell, Robert V. Lindsey, Rebecca M. Jones

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A Digital Tool for Clinical Evidence–Driven Guideline Development by Studying Properties of Trial Eligible and Ineligible Populations: Development and Usability Study by Shahzad Mumtaz, Megan McMinn, Christian Cole, Chuang Gao, Christopher Hall, Magalie Guignard-Duff, Huayi Huang, David A McAllister, Daniel R Morales, Emily Jefferson, Bruce Guthrie

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Prioritizing breast cancer surgeries: insights from the KRONOS SCORE by Lucía Navarro, Lucía Navarro, Lucía Navarro, Luis Perez-Bartivas, Luis Perez-Bartivas, Luis Perez-Bartivas, David Ponferrada, David Ponferrada, David Ponferrada, Javier Cejas, Javier Cejas, Javier Cejas, Juan Adrián Camús, Juan Adrián Camús, Juan Adrián Camús, Natalia Rangel, Natalia Rangel, Natalia Rangel, Maria Porras, Cristina Morales Estevez, Cristina Morales Estevez, Cristina Morales Estevez, Amalia Palacios Eito, Amalia Palacios Eito, Amalia Palacios Eito, Pilar Rioja, Pilar Rioja, Pilar Rioja, Marina Alvarez, Marina Alvarez, Marina Alvarez, Enrique Aranda, Enrique Aranda, Enrique Aranda, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez

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A patient-based iPSC-derived hepatocyte model of alcohol-associated cirrhosis reveals bioenergetic insights into disease pathogenesis by Bani Mukhopadhyay, Cheryl Marietta, Pei-Hong Shen, Abdul Oiseni, Faridoddin Mirshahi, Maria Mazzu, Colin Hodgkinson, Eli Winkler, Qiaoping Yuan, Daniel Miranda, George Kunos, Arun J. Sanyal, David Goldman

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Impact of the Smarter Safer Homes Solution on Quality of Life and Health Outcomes in Older People Living in Their Own Homes: Randomized Controlled Trial by Wei Lu, David Silvera-Tawil, Hwan-Jin Yoon, Liesel Higgins, Qing Zhang, Mohanraj Karunanithi, Julia Bomke, Joshua Byrnes, Jennifer Hewitt, Vanessa Smallbon, Jill Freyne, Deepa Prabhu, Marlien Varnfield

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Impact of metformin on disease control and survival in patients with head and neck cancer: a retrospective cohort study by Daniel J. Lee, Caitlin P. McMullen, Andrew Foreman, Shao Hui Huang, Lin Lu, Wei Xu, John R. de Almeida, Geoffrey Liu, Scott V. Bratman, David P. Goldstein

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The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin—A Randomized, Controlled, Crossover Study by Liva K. Stuhr, Joshua B. Feinberg, Thea Christoffersen, Konstantinos Dimopoulos, Mikkel B. Christensen, David P. Sonne, Troels Riis, Peter S. Plomgaard, Jens P. Goetze, Emil L. Larsen, Kristian Karstoft

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Development and Characterization of Anti-Nitr9 Antibodies by Radhika N. Shah, Ivan Rodriguez-Nunez, Donna D. Eason, Robert N. Haire, Julien Y. Bertrand, Valērie Wittamer, David Traver, Shila K. Nordone, Gary W. Litman, Jeffrey A. Yoder

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Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation by Daniel Czyzyk, Wupeng Yan, Simon Messing, William Gillette, Takashi Tsuji, Mitsuhiro Yamaguchi, Shinji Furuzono, David M. Turner, Dominic Esposito, Dwight V. Nissley, Frank McCormick, Dhirendra K. Simanshu

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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Ol... by Francis M. Finucane, Stephen J. Sharp, Mensud Hatunic, Alison Sleigh, Ema De Lucia Rolfe, Avan Aihie Sayer, Cyrus Cooper, Simon J. Griffin, David B. Savage, Nicholas J. Wareham

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Comparative cardiometabolic safety and effectiveness of aripiprazole in people with severe mental illness: A target trial emulation. by Alvin Richards-Belle, Alvin Richards-Belle, Naomi Launders, Sarah Hardoon, Al Richards, Kenneth K C Man, Neil M Davies, Elvira Bramon, Joseph F Hayes, David P J Osborn

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Induction of MASH in three-dimensional bioprinted human liver tissue. by Vaidehi Joshi, Dwayne Carter, Alice E Chen, Keith Murphy, J William Higgins, Mediha Gurel, Daisy Chilin Fuentes, Sara Brin Rosenthal, Kathleen M Fisch, Tatiana Kisseleva, David A Brenner

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Long-Term Results After Laparoscopic Lavage for Perforated Diverticulitis Purulent Peritonitis in Sweden: A Population-Based Observational Study by Andreas Samuelsson, MD, David Bock, PhD, Mattias Prytz, MD, PhD, Carolina Ehrencrona, BSc, Anette Wedin, RN, Eva Angenete, MD, PhD, Eva Haglind, MD, PhD

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Real world experience with [99mTc]Tc-HYNIC-iPSMA SPECT prostate cancer detection: interim results from the global NOBLE registry by Pete Tually, Virginia García Quinto, Yehia Omar, Fuad Novruzov, Ryan Yudistiro, Mike Sathekge, Geoffrey Currie, Paul Galette, Neel Patel, Tracey Brown, Gabriel Bolland, Rebecca Lo Bue, David Cade

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Comparing the emotional impact of the UK COVID-19 lockdown in very preterm and full-term born children: a longitudinal study by Zeyuan Sun, Zeyuan Sun, Laila Hadaya, Laila Hadaya, Marguerite Leoni, Marguerite Leoni, Paola Dazzan, Emily Simonoff, Serena J. Counsell, A. David Edwards, Chiara Nosarti, Chiara Nosarti, Lucy Vanes

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What are the cost-savings and health benefits of improving detection and management for six high cardiovascular risk conditions in England? An economic evaluation by Katy Cooper, Alan Brennan, David Bagguley, Helen Buckley Woods, Chloe Thomas, Penny Breeze, Michael Gillett, Edward Goka, Hazel Y Squires, Gilly Brenner, Joanna Leaviss, Mark Clowes, Laura Heathcote

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Parallel randomised trial testing community fibrosis assessment for suspected non-alcoholic fatty liver disease: outcomes from LOCATE-NAFLD by Sanjeewa Kularatna, James O'Beirne, Adrian Barnett, Patricia C Valery, Elizabeth Powell, Ingrid J Hickman, Ruth Tulleners, David Brain, Katherine Stuart, Carolyn McIvor, Elen Witness, Melanie Aikebuse

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Mapping mycological ignorance – checklists and diversity patterns of fungi known for West Africa by Meike Piepenbring, Jose G. Maciá-Vicente, Jean Evans I. Codjia, Carola Glatthorn, Paul Kirk, Yalemwork Meswaet, David Minter, Boris Armel Olou, Kai Reschke, Marco Schmidt, Nourou Soulemane Yorou

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Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

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Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis by Francisco Artime-Naveda, David Hevia, Rebeca Alonso-Arias, Carmen Martínez, Isabel Quirós-González, Rafael Cernuda-Cernuda, Alejando Alvarez-Artime, Iván Menéndez-Valle, Rosa M. Sainz, Juan C. Mayo

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