Clinical application of 3D slicer reconstruction and 3D printing localization combined with neuroendoscopy technology in VPS surgery by Long Zhou, Pan Lei, Ping Song, Zhiyang Li, Huikai Zhang, Hangyu Wei, Lun Gao, Qiuwei Hua, Hui Ye, Qianxue Chen, Silei Zhang, Qiang Cai

“…According to the unique ventricular system characteristics of each hydrocephalus patient, the 3D Slicer reconstruction technology was used to determine the individualized puncture point and direction, measure the puncture depth, accurately locate the puncture through the 3D printing guide plate, and accurately send the tip of the ventricular catheter into the frontal or central part of the lateral ventricle with the assistance of neuroendoscopic visualization, which improved the success rate of the operation and reduced the risk of tube blockage. …”
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Effects of perioperative oxycodone as the sole opioid on immunity within a multi-modal analgesia framework in patients undergoing cervical cancer surgery: A randomised controlled t... by Jingjing Liu, Sumeng Chen, Jianxiao Chen, Hailian Liu, Weiyi Li, Haomin Chi, Xiaowei Ding, Shaoqiang Huang

“…Within 24 h postoperatively, the visual analogue scale (VAS) scores for resting and movement-evoked pain were lower in Group O than in Group C (all P < 0.001), and the same was observed at 48 h postoperatively (both P = 0.002), as was the incidence of catheter-related bladder discomfort (P = 0.001). The VASs for postoperative analgesia satisfaction were higher in Group O than in Group C (P = 0.006). …”
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Comparative safety and effectiveness of cryoballoon versus radiofrequency ablation for atrial fibrillation: a systematic review and meta-analysis by Muhammad Furqan, Ifrah Inbisat Raza, Shaheera Younus, Hareer Fatima, Hiba Azhar, Sania Kaneez Fatima, Laiba Ali, Sara Khan, Aayat Ellahi

“…Traditionally, the main treatment for this condition has been pulmonary vein isolation (PVI) performed using radiofrequency catheter ablation (RFCA). However, another technique known as cryoballoon ablation (CBA) has been developed as another option for managing this heart rhythm disorder. …”
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Experimental research in comparison with effects of 6% dextran 70 and 7.5 % naci combinations and blood administrations for treatment of dogs with acute heamorrhagic shock syndrome by M. Arıcan, E. Keskin, C. Ceylan, K. Yiğitarslan

“…Haemorrhagic shock was performed experimentally by taking arterial blood via cut down catheters. By this way the mean arterial pressure was reduced to 40 ± 5 mmHg. …”
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Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study by Nawal M. Alanazi, Nasser H. Alshanbari, Hala M. Roushdy, Yahya I. Alnshbah, Eman Ali Barnawi, Nawaf M. Almatrafi, Rula Felemban, Zainah M. Al Shahrani, Nadeen Burhan, Aiman El-Saed, Khalid H. Alanazi

“…Almost all patients had devices: central line (63.6 %), foley catheters (52.7 %), or mechanical ventilation (50.4 %). …”
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Reducing door-to-balloon time in STEMI patients through instant messaging: An empirical study during the COVID-19 pandemic by Yi-Chun Yang, Chih-Tsung Liu, Bao-Tzung Wu

“…Conclusion: DTBT ≤90 min was positively correlated with DTET ≤10 min (r = 0.244, P < 0.01) and door-to-catheter room time (DTCT; r = 0.461, P < 0.01). The use of LINE instant messaging streamlined emergency room communication and reduced inefficiencies, but uncontrollable factors during the pandemic continued to affect PCI times. …”
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A Randomized Controlled Trial of Enhanced Recovery After Surgery Versus Standard of Care Recovery for Emergency Cesarean Deliveries at Mbarara Hospital, Uganda by Moris, Baluku, Francis, Bajunirwe, Joseph, Ngonzi, Joseph, Kiwanuka, Stephen, Ttendo

“…They also received early initiation of mobilization, feeding, and urethral catheter removal. The primary end point was length of hospital stay. …”
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Cathepsin G promotes arteriovenous fistula maturation by positively regulating the MMP2/MMP9 pathway by Lemei Hu, Changqing Zheng, Ying Kong, Zhiqing Luo, Fengzhang Huang, Zhigang Zhu, Quhuan Li, Ming Liang

“…A more comprehensive understanding and study of the mechanisms of AVF maturation is urgently needed.Methods and results In this study, we downloaded the publicly available datasets (GSE119296 and GSE220796) from the Gene Expression Omnibus (GEO) and merged them for subsequent analysis. …”
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Source attribution of human Campylobacter infection: a multi-country model in the European Union by Cecilie Thystrup, Maja Lykke Brinch, Clementine Henri, Lapo Mughini-Gras, Lapo Mughini-Gras, Eelco Franz, Kinga Wieczorek, Montserrat Gutierrez, Deirdre M. Prendergast, Geraldine Duffy, Catherine M. Burgess, Declan Bolton, Julio Alvarez, Julio Alvarez, Vicente Lopez-Chavarrias, Thomas Rosendal, Lurdes Clemente, Ana Amaro, Aldert L. Zomer, Katrine Grimstrup Joensen, Eva Møller Nielsen, Gaia Scavia, Magdalena Skarżyńska, Miguel Pinto, Mónica Oleastro, Wonhee Cha, Amandine Thépault, Katell Rivoal, Martine Denis, Marianne Chemaly, Tine Hald

“…Results using different sampling strategies were compared to assess the impact of unbalanced datasets on the prediction of the cases.ResultsThe results showed that the variety of sources sampled and the quantity of samples from each source impacted the performance of the model. …”
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Design of Command and Dispatch System for Automatic Reading of Meter Images in Substations by UAV Inspection Photos by Guanghong Deng, Liangpei Lin, Baihao Lin, Wenlong Jing, Xiaodan Zhao, Yong Li, Rui Yang, Shidun Xie, Pengfeng Wei

“…The experimental results show that in two datasets, The mean average precision of 50 (mAP50) accuracy of the YOLOv6n model using this method reached 99.71% and 98.60%, respectively, and the inference speed of a single image was 17.1[Formula: see text]ms and 13.2[Formula: see text]ms, respectively. …”
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Estimation of tuberculosis incidence at subnational level using three methods to monitor progress towards ending TB in India, 2015–2020 by Swati Mahajan, Amar Shah, Sarit Sharma, Rituparna Das, Kathiresan Jeyashree, Mathavaswami Vijayageetha, Bhavesh Modi, Burugina Nagaraja Sharath, Vijay Singh, Shamim Mannan, Sairu Philip, Jasleen Kaur, Ranjani Ramachandran, Raghuram Rao, Sriram Selvaraju, Bency Joseph, Vaibhav Shah, Kiran Rade, Lalit Sankhe, Surinder Singh, Sandeep Chauhan, Anupam Banerjee, Devender Kumar, Ganapathy Kalaiselvan, Bhavin Vadera, Paras Mehta, Meenakumari Natarajan, Manoj Murhekar, Aswathy Sreedevi, Jeromie Thangaraj, Saravanakumar Velusamy, Sasidharan Akhil, Dhanapal Sudha Rani, Ramasamy Sabarinathan, Sakthivel Manikandanesan, Rajalakshmi Elumalai, Amarendra Mahapatra, Almas Shamim, Ashok Bhardwaj, Anil Purty, Anand Sridhar, Aniket Chowdhury, Asif Shafie, Avijit Choudhury, Deka Dhrubjyoti, Hardik Solanki, Krushna Sirmanwar, Kshitij Khaparde, Malik Parmar, Nisha Dahiya, Parija Debdutta, Quazi Ahmed, Ranjeet Prasad, Rohini Shinde, Rupali Baruah, Sandip Bharaswadkar, Shanta Achanta, Shibu Balakrishnan, Shivani Chandra, Sophia Khumukcham, Sudarsan Mandal, Sumitha Chalil, Venkatesh Roddawar, Kuldeep Sachdeva, Jayakrishna Kurada, Mayank Sharma, Debajyoti Mohapatra, Yogesh Patel, Sapna Thekkepat, Karthikeyan Kumaraswamy, Mallika Tharakan, Shramana Majumdar, Vrinda Manocha, Sukriti Chauhan, Shekhar Waikar, Puja Ambule, Krithika Murali, Devi Madhavi Bhimarasetty, Tulika Goswami, Darshan Mahyavanshi, Krutarth Bhrahmbhatt, Bhautik Modi, Anmol Gupta, Sunil Raina, Rajiv Kumar Gupta, Ratnesh Sinha, Manju Toppo, Gajen Medhi, Swati M Patki, Bishnu Ram Das, Lisa Sarangi, Afsal Hakim, Suresh Balan, Baer Philip Ravikumar, Subrata Baidya, Abhik Sinha, Boddepalli Nagendra Naidu, Bikash Chandra Nayak, Anoop Dev, Pallavi Boro, Debarshi Paul, Amrita Sarkar, Bhavesh Bariya, Jatin Chhaya, Dixit Chauhan, Mithun Sanghavi, Nilesh Thakor, Rohit Ram, Hinal Baria, Abhilash Sood, Anupam Parashar, Yangchen Dolma, Rakesh Bahl, Dilip Kumar, Mohammad Salim Khan, A K Jayasree, Zinia Nujum, Sheela P Haveri, Dinesh Bhatnagar, Subrata Kumar Palo, Priyesh Marskole, Prashant Verma, Dinesh Kumar Pal, Neelam Toppo, Sanjay R Quraishi, Sunil Panigrahi, Rambadan Chauhan, Jayashree Gothankar, Swapnali S Kadam, Dasi Rao, Sudhir Wanje, Pallavi Uplap, Ningombam Joenna Devi, Rikrak Ch Marak, Markordor Lyngdoh, Manoj B Patki, Satyajit Sundar Ray, Kavita Vasudevan, Mahesh Satija, Mahesh Choudhary, Mitin Parmar, Venkatesh Govindasamy, Karlapudi Nitesh Kumar, Goutham Thumari, Amar Tripura, Chanda Mog, Shampa Das, Ritesh Singh, Chandra Shekar Maity, Mamta Gehlawat

“…Objectives We verified subnational (state/union territory (UT)/district) claims of achievements in reducing tuberculosis (TB) incidence in 2020 compared with 2015, in India.Design A community-based survey, analysis of programme data and anti-TB drug sales and utilisation data.Setting National TB Elimination Program and private TB treatment settings in 73 districts that had filed a claim to the Central TB Division of India for progress towards TB-free status.Participants Each district was divided into survey units (SU) and one village/ward was randomly selected from each SU. …”
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Intratumoural CD8+ CXCR5+ follicular cytotoxic T cells have prognostic value and are associated with CD19+ CD38+ B cells and tertiary lymphoid structures in colorectal cancer by Fangze Wei, Xiaotian Xu, Jing Wang, Shi Wen Mei, Fu Qiang Zhao, Fei Huang, Ti Xian Xiao, Guo Jing Wang, Baojun Wei, Shengkai Huang, Wei Cui

“…Methods We explored the expression of TFC cell in tumor tissues and peripheral blood in our clinical cohort and public datasets. By combining single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing, we explored the potential function of TFC cells and developed a prediction model for CRC. …”
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Sex-specific differences in children attending the emergency department: prospective observational study by Joany M Zachariasse, Henriette A Moll, Ian K Maconochie, Ewout W Steyerberg, Daan Nieboer, Dorine M Borensztajn, Claudio F Alves, Frank J Smit, Susanne Greber-Platzer, Claudia M G Keyzer-Dekker

“…Objective To assess the role of sex in the presentation and management of children attending the emergency department (ED).Design The TrIAGE project (TRiage Improvements Across General Emergency departments), a prospective observational study based on curated electronic health record data.Setting Five diverse European hospitals in four countries (Austria, The Netherlands, Portugal, UK).Participants All consecutive paediatric ED visits of children under the age of 16 during the study period (8–36 months between 2012 and 2015).Main outcome measures The association between sex (male of female) and diagnostic tests and disease management in general paediatric ED visits and in subgroups presenting with trauma or musculoskeletal, gastrointestinal and respiratory problems and fever. …”
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Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation by Jinru Cui, Heli Li, Cong Hu, Feiyan Zhang, Yunjie Li, Ying Weng, Liping Yang, Yingying Li, Minglan Yao, Hao Li, Xiaoping Luo, Yan Hao

“…Methods: ASD-related datasets were obtained from GEO database, and HIF1A-related genes from GeneCards. …”
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Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study by Julien Greggio, Christina Malamateniou, Kelly Pegoretti Baruteau, Constantino Carlos Reyes-Aldasoro, Odaro J. Huckstep, Jane M. Francis, Wilby Williamson, Paul Leeson, Adam J. Lewandowski, Winok Lapidaire

“…High-resolution three-dimensional Time-of-Flight Magnetic Resonance Angiography (3D TOF MRA) datasets were analysed, measuring vessel diameters and classifying segments into different groups of CoW anatomical variations. …”
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TAME 2.0: expanding and improving online data science training for environmental health research by Alexis Payton, Alexis Payton, Alexis Payton, Elise Hickman, Elise Hickman, Elise Hickman, Jessie Chappel, Jessie Chappel, Jessie Chappel, Kyle Roell, Kyle Roell, Lauren E. Koval, Lauren E. Koval, Lauren A. Eaves, Lauren A. Eaves, Chloe K. Chou, Chloe K. Chou, Chloe K. Chou, Allison Spring, Allison Spring, Sarah L. Miller, Sarah L. Miller, Sarah L. Miller, Oyemwenosa N. Avenbuan, Oyemwenosa N. Avenbuan, Oyemwenosa N. Avenbuan, Rebecca Boyles, Rebecca Boyles, Paul Kruse, Cynthia V. Rider, Grace Patlewicz, Caroline Ring, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Ilona Jaspers, Rebecca C. Fry, Rebecca C. Fry, Rebecca C. Fry, Julia E. Rager, Julia E. Rager, Julia E. Rager, Julia E. Rager

“…Also new to TAME 2.0 are “Test Your Knowledge” activities at the end of each training module, in which participants are asked additional module-specific questions about the example datasets and apply skills introduced in the module to answer them. …”
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Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma by Chun-Nan Yeh, Yu-Chan Chang, Yi-Chen Yeh, Yu-Chao Wang, Dennis Shin-Shian Hsu, Meng-Lun Lu, Michael Hsiao, Ming-Huang Chen, Nai-Jung Chiang, Shin-Yi Chung, Chien-Jung Huang, Ming-Hsien Chan, Tzu-Sheng Hsu, Yi-Ping Hung

“…This study elucidates their contributions to the TME.Methods We examined 16 tumor samples from a single-arm, phase II trial of nivolumab plus modified gemcitabine and S-1 and various datasets. Immunohistochemistry and RNA sequencing were employed to assess TLSs and TILs presence and activity. …”
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Acetylation of proximal cysteine-lysine pairs by alcohol metabolism by Courtney D. McGinnis, Peter S. Harris, Brenton I.M. Graham, John O. Marentette, Cole R. Michel, Laura M. Saba, Richard Reisdorph, James R. Roede, Kristofer S. Fritz

“…Interrogating both cysteine redox and lysine acetylation datasets, 1280 protein structures generated by AlphaFold2 represented by a 3D spatial matrix were used to quantify the distances between 557,815 cysteine and lysine residues. …”
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Methods to Adjust for Confounding in Test-Negative Design COVID-19 Effectiveness Studies: Simulation Study by Elizabeth AK Rowley, Patrick K Mitchell, Duck-Hye Yang, Ned Lewis, Brian E Dixon, Gabriela Vazquez-Benitez, William F Fadel, Inih J Essien, Allison L Naleway, Edward Stenehjem, Toan C Ong, Manjusha Gaglani, Karthik Natarajan, Peter Embi, Ryan E Wiegand, Ruth Link-Gelles, Mark W Tenforde, Bruce Fireman

“…The performance of VE estimators is evaluated across a multinomial vaccination exposure in simulated datasets. ResultsBias in VE estimates from multivariable models ranged from –5.3% to 6.1% across 4 levels of vaccination. …”
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Bulk and single-cell transcriptome revealed the metabolic heterogeneity in human glioma by Yong Xiao, Mengjie Zhao, Ran Wang, Liang Liu, Chong Xiang, Taiping Li, Chunfa Qian, Hong Xiao, Hongyi Liu, Yuanjie Zou, Xianglong Tang, Kun Yang

“…Methods: Energy-related features of glioma were characterized through integrative analyses of multiple datasets, including bulk, single-cell, and spatial transcriptome profiling. …”
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