Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma by Zihao Sun, Mengfei Hu, Xiaoning Huang, Minghan Song, Xiujing Chen, Jiaxin Bei, Yiguang Lin, Size Chen

“…Performance of the prognostic model, DCRGS, for the prognostic evaluation, was assessed using a multiple time-dependent receiver operating characteristic (ROC) curve, the R package, “timeROC”, and validated using GEO datasets. Results Analysis of scRNA-seq data showed that there is a significant upregulation of LGALS9 expression in DCs isolated from malignant pleural effusion samples. …”
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Characterising melanoma diagnostic pathways for patients in routine practice using administrative health data in Ontario, Canada: a population-based study by Frances C Wright, Timothy P Hanna, Patti A Groome, Nicole J Look Hong, Meaghan E Mavor, Yuka Asai, Hugh Langley

“…Objective To characterise diagnostic pathways for patients with melanoma in routine practice and compare patient, disease and diagnostic interval (DI) characteristics across pathways.Design Descriptive cross-sectional study using administrative health data.Setting Population-based study in Ontario, Canada.Participants Patients with melanoma diagnosed from 2007 to 2019.Main outcome measures We used latent class cluster analysis to create clusters of patients with similar diagnostic experiences to characterise diagnostic pathways in routine practice. …”
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Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…In this study, we explored the role of aging-related genes (ARGs) in UC pathogenesis and diagnosis prediction.Methods: Gene expression data were obtained from four independent datasets (GSE75214, GSE87466, GSE94648, and GSE169568) in the GEO database, and ARGs were derived from multiple public databases. …”
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Desain Faktorial untuk Pembuktian Teori Masters dalam Penentuan Jumlah Lapisan dan Neuron Tersembunyi pada Peramalan Multivariat dengan Jaringan Syaraf Tiruan by Dwi Ayu Lusia, Awalludiyah Ambarwati

“…The more hidden layers will obtain better RMSE in both training dan testing datasets. Thus, the Masters Theory which states that there is no reason to use more than two hidden layers, proved to be invalid. …”
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Identification and Verification of Novel Biomarkers Involving Rheumatoid Arthritis with Multimachine Learning Algorithms: An In Silicon and In Vivo Study by Fucun Liu, Juelan Ye, Shouli Wang, Yang Li, Yuhang Yang, Jianru Xiao, Aimin Jiang, Xuhua Lu, Yunli Zhu

“…We retrieved RA-related and pan-cancer information datasets from the Gene Expression Omnibus and The Cancer Genome Atlas databases, respectively. …”
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Phylogeography and genetic diversity of Ulmus elongata (Ulmaceae), a Tertiary relict tree with extremely small populations (PSESP) by Yakun Wang, Xiankun Wang, Junyuan Wu, Jun Yang, Yanpei Liu, Peng Guo, Fude Shang, Nan Lin

“…Utilizing chloroplast genome datasets, we found that U. elongata exhibited remarkably low nucleotide diversity and gene flow (π = 0.00013, Nm = 0.03). …”
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A Realistic Approach to Calculating the Nitrogen Use Efficiency Index in Cereals with Winter Wheat (<i>Triticum aestivum</i> L.) as an Example by Witold Grzebisz, Jarosław Potarzycki

“…Two groups of N pools (soil <i>N_min</i> and N mass in the wheat biomass) were determined in BBCH 30, 58, and 89. These core datasets were used to calculate total N input (<i>N_in</i>) to the soil/crop system during the two main periods of WW growth: (1) before (vegetative mega-phase, V) and (2) after wheat flowering (reproductive mega-phase, R, or grain filling period, GFP). …”
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The Impact of Lockdown on Air Quality in Pakistan during the COVID-19 Pandemic Inferred from the Multi-sensor Remote Sensed Data by Rehana Khan, Kanike Raghavendra Kumar, Tianliang Zhao

“…We focused on assessing the significant changes of pollutant concentrations during March–May for the years 2019 and 2020 utilizing the satellite datasets observed from the Moderate Resolution Imaging Spectroradiometer (MODIS), Ozone Monitoring Instrument (OMI), Atmospheric Infrared Sounder (AIRS), and Modern-Era Retrospective analysis for Research and Applications (MERRA-2) reanalysis data. …”
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Insights gained through real-time monitoring of porcine reproductive and respiratory syndrome virus and description of temporal trends based on laboratory data in Ontario, Canada by Tatiana Petukhova, Maria Spinato, Tanya Rossi, Michele T. Guerin, Cathy A. Bauman, Pauline Nelson-Smikle, Davor Ojkic, Zvonimir Poljak

“…The final optimized, aggregated, and anonymized datasets were exported to the Tableau server and were used to design dynamic real-time visualizations with Tableau Desktop v.2021.4. …”
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LURAP1L-AS1 long noncoding RNA promotes breast cancer progression and associates with poor prognosis by Radhakrishnan Vishnubalaji, Dania Awata, Nehad M. Alajez

“…Bioinformatics analysis predicted LURAP1L-AS1 to function as a competitive endogenous RNA (ceRNA), sponging key microRNAs, such as miR-7a-5p, miR-101-3p, miR-181a-5p, and miR-27a-3p, thereby modulating oncogenes including EZH2, MCL1, and KRAS, which are linked to increased cancer cell survival, proliferation, and metastasis.In addition to its role in TNBC, correlation analysis using breast cancer patient datasets revealed a significant association between LURAP1L-AS1 and ESR1 expression, suggesting its broader impact across breast cancer subtypes. …”
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Tumor-Stroma Ratio is a Critical Indicator of Peritoneal Metastasis in Gastric Cancer by Zhong L, Huang H, Hou D, Zhou S, Lin Y, Yu Y, Yu J, Han F, Xie L

“…Additionally, the correlation between TSR and PM in GC was analyzed using Gene Expression Omnibus (GEO) datasets. To validate TSR’s clinical potential in diagnosing PM, 640 GC patients from two medical centers were enrolled. …”
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Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform? by Godsway Edem Kpene, Sylvester Yao Lokpo, Sandra A. Darfour-Oduro

“…The accuracy for (test and train datasets) were as follows: (90% and 90%), (100% and 100%), (90% and 90%), (90% and 88%) and (88% and 90%) respectively for the various ML classification techniques: logistic regression, Decision tree classifier, kNN classifier, SVM and XGBoost. …”
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Estimating undiagnosed dementia in England using capture recapture techniques by Naaheed Mukadam, Louise Marston, Katie Flanagan, Etuini Ma’u, Gary Cheung, Dankmar Böhning

“…We tabulated capture of dementia in each of the two datasets and used the Lincoln-Petersen estimator to estimate numbers of missing dementia diagnoses per year along with the estimated total number of cases and the proportion of cases identified. …”
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Evaluation of Ecosystem Services and Tradeoff and Synergy in the Alpine and Canyon Region of Southwest China Based on Multi-source Geographic Data by LIU Jing, XIANG Jiayi, ZHANG Donghai, LAN Mengyao, GUAN Yinghui

“…[Methods] Three typical ecosystem services in the alpine and canyon region of southwest China from 2000 to 2020 were systematically evaluated using the InVEST model, RUSLE model, and WR index, in combination with multi-source geographic datasets. [Results] (1) From 2000 to 2020, carbon sequestration and water retention services in the alpine and canyon region of southwest China were steadily improved, with annual carbon sequestration increasing from 1 927 g/(m2·a) to 1985 g/(m2·a), and the WR index rising from 0.062 to 0.067. …”
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Interplay of NF-κB and PPAR-γ transcription factors in patients with juvenile systemic lupus erythematosus by Ozgur Kasapcopur, Sezgin Sahin, Amra Adrovic, Kenan Barut, Sinem Durmus, Remise Gelisgen, Hafize Uzun

“…However, our findings must be regarded as hypothesis-generating and confirmed in larger datasets. Moreover, their roles in monitoring the course of a disease and guiding therapeutic strategies in juvenile systemic autoimmune diseases need to be clearly investigated. …”
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To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation by Sha Li, Jingshan Chen, Wenjing Zhou, Yonglan Liu, Di Zhang, Qian Yang, Yuerong Feng, Chunli Cha, Li Li, Guoyong He, Jun Li

“…The GSE96804 (DN:control=41:20) and GSE104948 (DN:control=7:18) DN-related datasets and 924 propionate metabolism-related genes (PMRGs) and 656 fibrosis-related genes (FRGs) were acquired from the public database. …”
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Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude by Xiaozhen Liu, He Ding, Xiaoxue Zhang, Na Ta, Jinmei Zhao, Qian Zhang, Huiyun Liu, Mengjiao Sun, Xiaoqing Zhang

“…Most of these enzymes were expressed in rumen metatranscriptome datasets, especially in Prevotella spp. and Ruminococcus spp., suggesting that gastrointestinal microbial communities in ruminants play major roles in the digestion of plant biomass to provide nutrition and energy for the host. …”
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Evaluation of the Effectiveness of Soil Improvement Measures in Apple Orchards on the Loess Plateau: A Meta-Analysis by DUAN Shunxia, LIU Jiayuan, ZHAO Hongxiang, LI Yangyang

“…[Methods] Based on 75 publications and 1 302 field trial datasets on soil improvement in the apple orchards of the Loess Plateau, meta-analysis and principal component analysis (PCA) were used to quantitatively evaluate the effects of different improvement measures, including mulching, fertilization, and soil conditioners, on soil quality. …”
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Establishment and validation of a nomogram for coronary artery lesions in children with Kawasaki disease by Chong Hu, Chong Hu, Xiao Yan, Henglian Song, Qin Dong, Qin Dong, Changying Yi, Changying Yi, Jianzhi Li, Jianzhi Li, Xin Lv, Xin Lv

“…A nomogram based on these predictors was established and successfully validated in both datasets. In the training set, the AUC was 0.819 and in the validation set it was 0.844. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…To achieve that, we applied CirComPara2 pipeline to publicly available datasets to identify the differently expressed circRNAs in the LNCaP cell lines pre- and post-transdifferentiation. …”
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