Identification of potential druggable targets for endometriosis through Mendelian randomization analysis by Peng Chen, Xin Wei, Xiao-Ke Li, Yi-Hang Zhou, Yi-Hang Zhou, Qi-Fang Liu, Ling Ou-Yang

“…This study aimed to identify both cerebrospinal fluid (CSF) and plasma protein markers as promising therapeutic targets for EM.MethodsWe utilized Mendelian randomization (MR) analysis to explore potential disease-causing proteins, utilizing genetic datasets from genome-wide association studies (GWAS) and protein quantitative trait loci (pQTL) analyses. …”
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Exploring the upper ocean characteristics of a bay using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran

“…The utilization of a Taylor diagram further supports the validation and excellent performance of the model compared to other available datasets. During the simulation, there is a high correlation (0.96) between the evolution of the salinity and temperature values obtained from the model and the corresponding data from the World Ocean Atlas. …”
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Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

“…However, ferroptosis-related genes (FRGs) have not been systematically identified and verified in AAD.Methods and Results: Seven human AAD datasets downloaded from Gene Expression Omnibus were analyzed, and 113 potential AAD-related FRGs were identified. …”
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Large-scale spatio-temporal variation in vital rates and population dynamics of an alpine bird by Nater, Chloé R., Frassinelli, Francesco, Martin, James A., Nilsen, Erlend B.

“…Integrated population models (IPMs), for example, are able to use multiple streams of data from different field monitoring programmes and/or multiple aspects of single datasets to estimate population sizes and key vital rates. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Methods The lung cancer datasets for this study were directly downloaded from The Cancer Genome Atlas (TCGA). …”
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A nomogram for predicting bladder dysfunction in patients with type 2 diabetes mellitus: a retrospective study by Yingjie Hu, Fengming Hao, Ying Wang, Ling Chen, Lihua Wen, Jue Li, Wei Ren, Wenzhi Cai

“…The area under the curve (AUC) for the training and validation datasets was 0.897 and 0.862, respectively. The calibration curve showed a high degree of consistency. …”
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Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study by Carmen Tsang, Robert Wood, Tendai Mugwagwa, Kiran K Rai, Jingyan Yang, Theo Tritton, Jennifer L Nguyen, Kathleen Michelle Andersen, Maya Reimbaeva, Leah J McGrath, Poppy Payne, Bethany Emma Backhouse, Diana Mendes, Rebecca Butfield, Kevin Naicker, Mary Araghi

“…Objectives To quantify direct costs and healthcare resource utilisation (HCRU) associated with acute COVID-19 in adults in England.Design Population-based retrospective cohort study using Clinical Practice Research Datalink Aurum primary care electronic medical records linked to Hospital Episode Statistics secondary care administrative data.Setting Patients registered to primary care practices in England.Population 1 706 368 adults with a positive SARS-CoV-2 PCR or antigen test from August 2020 to January 2022 were included; 13 105 within the hospitalised cohort indexed between August 2020 and March 2021, and 1 693 263 within the primary care cohort indexed between August 2020 and January 2022. …”
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Patterns of colonic dismotility and visceral hypersensitivity at various clinical variants of irritable bowel syndrome by Ekaterina A. Bubnova, O. Yu. Fomenko, I. L. Khalif, V. V. Pavlenko

“…The motor function of the colon was studied by solid-state catheter manometry method. The balloon-dilatation test was applied to studying of VHS. …”
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Early mobilisation in Windhoek intensive care units: Practices, attitudes and barriers by Ilse du Plessis, Savarna Francis, Brenda Morrow

“…Mobility practices were conservative, especially when patients were intubated or in the presence of radial and femoral catheters. Major patient-level barriers included medical instability (n = 24, 72.7%) and excessive sedation (n = 18, 54.5%); whereas institutional barriers were the requirement for a doctor’s referral (n = 22, 64.7%) and no written guidelines or protocols for mobilisation (n = 16, 47.1%). …”
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Short-Term Clinical Outcomes after Using Novel Deeper Intubation Technique (DIT) of Ileus Tube for Acute Bowel Obstruction Patients by Yanlu Tan, Haibin Chen, Wenji Mao, Qin Yuan, Jun Niu

“…We developed a novel intubation technique, named Deeper Intubation Technique (DIT), by using the Zebra Urological Guidewire and digital gastrointestinal fluoroscopy, where we deepened the catheter intubation, and further compared the effects of DIT with the Traditional Intubation Technique (TIT) on the short-term clinical outcomes of 183 patients. …”
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Tailoring the Ablative Strategy for Atrial Fibrillation: A State-of-the-Art Review by Zefferino Palamà, Martina Nesti, Antonio Gianluca Robles, Antonio Scarà, Silvio Romano, Elena Cavarretta, Maria Penco, Pietro Delise, Mariano Rillo, Leonardo Calò, Luigi Sciarra

“…Among the many methods proposed, recently the use of high-density mapping and multipolar catheters seems of particular benefit in order to clarify the arrhythmia mechanisms. …”
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Cost of Intravenous Analgesia for the Management of Acute Pain in the Emergency Department is Substantial in the United States by Pamela P. Palmer, Judith A. Walker, Asad E. Patanwala, Carin A. Hagberg, John A. House

“…Of these 7.3 million encounters, 4.3 million (58%) did not lead to hospital admission of the patient and, therefore, the patient may have only required an IV catheter for opioid administration. **Conclusions:** IV opioid use in the ED is indicated for moderate-to-severe pain but is associated with significant costs. …”
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Incidence, Outcomes, and Factors Associated with Intra-Abdominal Hypertension and Primary Abdominal Compartment Syndrome in Abdominopelvic Injury Patients by Amonpon Kanlerd, Krissada Nakornchai, Karikarn Auksornchart, Warapan Watkwaw

“…The bladder pressure was recorded every 4 hours until the urethral catheter was removed. Data of age, gender, weight, height, body mass index, injury mechanisms, initial vital signs, imaging, laboratory data, blood component requirements, abdominal organs involved, treatments including surgery and intervention radiology, abbreviated injury scale (AIS) and injury severity score (ISS), length of ICU stays, and results of treatment were all analyzed. …”
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Principales enfermedades que afectan el cultivo de la caña de azúcar en Ecuador by Hipólito Israel Pérez Iglesias, Irán Rodriguez Delgado, Rigoberto Miguel García Batista

“…La mejor medida de control para erradicar estas enfermedades es la utilización de cultivares resistentes, como la ECU-01, ECU-02, ECU-03 y ECU-04, empleo de semilla categorizada para realizar las nuevas plantaciones comerciales, la desinfección de las herramientas usadas en campo, principalmente el machete, utilizando una solución de formol al 1% o amonio cuaternario, otra medida no menos importante es el control de pulgones que sirven como vectores de varias enfermedades, además de mantener una vigilancia fitosanitaria permanente. …”
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Failure of Urological Implants in Spinal Cord Injury Patients due to Infection, Malfunction, and Implants Becoming Obsolete due to Medical Progress and Age-Related Changes in Human... by Subramanian Vaidyanathan, Bakul Soni, Gurpreet Singh, Peter Hughes, Fahed Selmi, Paul Mansour

“…This patient was therefore established on urethral catheter drainage. Later, infection with Staphylococcus aureus around the receiver block necessitated its removal. …”
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Early referral to nephrological care improves long-term survival and hospitalization after dialysis initiation, independent of optimal dialysis start – a call for harmonization of... by Mathias Haarhaus, Lavinia O. Bratescu, Nicolae Pana, Emanuela M. Gemene, Eliana M. Silva, Carla Alexandra R. Santos Araujo, Fernando Macario

“…At dialysis start, ER patients had higher hemoglobin, phosphate, and albumin levels and started dialysis less often via a central dialysis catheter (p < 0.001 for each). Logistic regression analysis demonstrated an independent lower risk for frequent hospitalizations for ER patients (odds ratio 0.22 (95% confidence interval 0.1–0.485), p < 0.001), and Cox regression analysis revealed an improved survival (hazard ratio 0.540 (95% confidence interval 0.325–0.899), p = 0.02), both independent of optimal dialysis start. …”
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The biodegradation of low-density polyethylene by Bacillus species by Felicia E. Uwakwe, Tobias I.N. Ezejiofor, Ernest A.A. Anyalogbu, Toochukwu E. Ogbulie

“…The ability of the microbial isolates to degrade polyethylene (table water sachets) was determined using microbial growth measurement in liquid medium (Optical Density (OD600)), disappearance and introduction of functional groups (Fourier Transform Infrared spectroscopy (FTIR) and weight loss analysis measured after sixty (60) days of incubation in mineral salt vitamin media. …”
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Retrograde Percutaneous Coronary Intervention in a Case of Takayasu Arteritis with Left Main Coronary Artery Chronic Total Occlusion by Prathap Kumar, Blessvin Jino, Stalin Roy, Manu Rajendran

“…Her coronary angiogram showed total occlusion of the left main coronary artery (LMCA) ostium and atretic LIMA graft. Since the guiding catheter could not engage the LMCA, a retrograde approach was planned. …”
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Perioperative nursing management of transcatheter edge-to-edge repair (经导管二尖瓣缘对缘修复术围手术期护理) by LIU Yuan (刘苑), LAI Jianqing (赖间清), DING Fei (丁菲), HUANG Huifen (黄惠芬)

“…The comprehensive interventions including enhanced recovery after surgery, respiratory exercise, pain control, catheter maintenance and standard health education before discharge were carried out to relieve symptoms of heart failure, improve self-care ability and quality of life of patients after transcatheter edge-to-edge repair. …”
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Defining New Research Questions and Protocols in the Field of Traumatic Brain Injury through Public Engagement: Preliminary Results and Review of the Literature by Shumaila Hasan, Aswin Chari, Mario Ganau, Chris Uff

“…To gauge acceptance of this, and as per the guidelines set out by the National Research Ethics Service, we conducted a survey of TBI and non-TBI patients admitted to our Trauma ward and their families. 100 responses were collected between December 2017 and July 2018, incorporating two redesigns in response to patient feedback. 75.0% of respondents said that they would consent to a brain biopsy performed at the time of insertion of an intracranial pressure (ICP) bolt. 7.0% replied negatively and 18.0% did not know. 70.0% would consent to insertion of a jugular bulb catheter to obtain paired intracranial venous samples and peripheral samples for analysis of biomarkers. …”
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