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29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses
Published 2022-01-01“…We performed a database mining on 102 transcriptomic datasets for the expressions of 29 m6A-RNA methylation (epitranscriptomic) regulators (m6A-RMRs) in 41 diseases and cancers and made significant findings: (1) a few m6A-RMRs were upregulated; and most m6A-RMRs were downregulated in sepsis, acute respiratory distress syndrome, shock, and trauma; (2) half of 29 m6A-RMRs were downregulated in atherosclerosis; (3) inflammatory bowel disease and rheumatoid arthritis modulated m6A-RMRs more than lupus and psoriasis; (4) some organ failures shared eight upregulated m6A-RMRs; end-stage renal failure (ESRF) downregulated 85% of m6A-RMRs; (5) Middle-East respiratory syndrome coronavirus infections modulated m6A-RMRs the most among viral infections; (6) proinflammatory oxPAPC modulated m6A-RMRs more than DAMP stimulation including LPS and oxLDL; (7) upregulated m6A-RMRs were more than downregulated m6A-RMRs in cancer types; five types of cancers upregulated ≥10 m6A-RMRs; (8) proinflammatory M1 macrophages upregulated seven m6A-RMRs; (9) 86% of m6A-RMRs were differentially expressed in the six clusters of CD4+Foxp3+ immunosuppressive Treg, and 8 out of 12 Treg signatures regulated m6A-RMRs; (10) immune checkpoint receptors TIM3, TIGIT, PD-L2, and CTLA4 modulated m6A-RMRs, and inhibition of CD40 upregulated m6A-RMRs; (11) cytokines and interferons modulated m6A-RMRs; (12) NF-κB and JAK/STAT pathways upregulated more than downregulated m6A-RMRs whereas TP53, PTEN, and APC did the opposite; (13) methionine-homocysteine-methyl cycle enzyme Mthfd1 downregulated more than upregulated m6A-RMRs; (14) m6A writer RBM15 and one m6A eraser FTO, H3K4 methyltransferase MLL1, and DNA methyltransferase, DNMT1, regulated m6A-RMRs; and (15) 40 out of 165 ROS regulators were modulated by m6A eraser FTO and two m6A writers METTL3 and WTAP. …”
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EMS3D-KITTI: Synthetic 3D dataset in KITTI format with a fair distribution of Emergency Medical Services vehicles for autodrive AI model trainingZenodo
Published 2025-02-01“…However, the need for large, precisely labelled datasets limits the detection of specialized and less common objects, such as Emergency Medical Service (EMS) and law enforcement vehicles. …”
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Improving Image Quality and Controllability in Speed + Angular Velocity to Image Generation Through Synthetic Data for Driving Simulator Generation
Published 2025-01-01Subjects: “…Synthetic dataset…”
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Possibility of the Use of Public Microarray Database for Identifying Significant Genes Associated with Oral Squamous Cell Carcinoma
Published 2012-03-01Subjects: “…combined dataset…”
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A Clinical Data Analysis Based Diagnostic Systems for Heart Disease Prediction Using Ensemble Method
Published 2023-12-01Subjects: Get full text
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Improving doublet cell removal efficiency through multiple algorithm runs
Published 2025-01-01Subjects: Get full text
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Advancing Wildlife Protection: Mask R-CNN for Rail Track Identification and Unwanted Object Detection
Published 2023-01-01Subjects: Get full text
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Data on battery health and performance: Analysing Samsung INR21700-50E cells with advanced feature engineering
Published 2025-04-01Subjects: “…Battery dataset…”
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Evaluation of the Impact of Morphological Differences on Scale Effects in Green Tide Area Estimation
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Deteksi Dini Gangguan Jaringan Distributed Denial Of Service (DDOS) Menggunakan Metode Shannon Entropy Pada Software Defined Network (SDN)
Published 2024-07-01Subjects: “…deteksi dini, Software Defined Networking, teori informasi, distributed denial of service, dataset, lalu lintas.…”
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USING MULTIPLE LINEAR REGRESSIONS TO DERIVE CROPLAND AND PASTURE PROPORTION MAPS IN ROMANIA
Published 2015-12-01Subjects: “…geospatial datasets…”
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Deep learning for object recognition: A comprehensive review of models and algorithms
Published 2025-12-01Subjects: Get full text
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Computer Vision-Based Patched and Unpatched Pothole Classification Using Machine Learning Approach Optimized by Forensic-Based Investigation Metaheuristic
Published 2021-01-01“…To establish the hybrid FBI-SVC framework, an image dataset consisting of 600 samples has been collected. …”
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