Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus by Maofei Zhu, Maofei Zhu, Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Junfeng Li, Silin Chen, Lin Li, Lin Li, Lin Li

“…Therefore, a deeper understanding of the therapeutic targets and the mechanisms underlying its occurrence and development is of great importance for early diagnosis, identification of potential therapeutic agents and improvement of the prognosis for patients.MethodsFirstly, the dataset of SCCE was downloaded from the GEO database and GEO2R tool was employed for the analysis of differentially expressed genes (DEGs). …”
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Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa by Katrien F.M. Bracké, Laura Monteiro Rente Dias, Marisha N. Meijer, Cathelijne P.M. Steegers, Laurinde F. den Heijer, Tess van der Harst, Marjolein H.G. Dremmen, Meike W. Vernooij, Gwen C. Dieleman, Tonya White

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Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T by Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner

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Modifiable Risk Factors Including Self-Perceived Stress for Breast Cancer in Hong Kong: A Case-Control Study of 10 757 Subject by Winnie Yeo, Lok-Wa Yuen, Kelvin Kam-Fai Tsoi, Emily Ying-Yang Chan, Carol C Kwok, Inda Soong, Ting-Ying Ng, Joanne Chiu, Miranda Chan, Sharon Wing-Wai Chan, Ting-Ting Wong, Yolanda Ho-Yan Chan, Lawrence Pui-Ki Li, Chun-Chung Yau, Wai-Ka Hung, Polly Suk-Yee Cheung

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Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traitsResearch in context by Lennart Riemann, Rodrigo Gutierrez, Ivan Odak, Joana Barros-Martins, Lennart M. Roesner, Ximena Leon Lara, Christine Falk, Thomas F. Schulz, Gesine Hansen, Thomas Werfel, Reinhold Förster, Berislav Bošnjak, Felix Jenniches, Norman Klopp, Till Robin Lesker, Martin Stangel

“…Data were analyzed using unsupervised clustering and multi-dataset integration approaches. Findings: We studied 97 innate and adaptive immune cell populations, revealing intricate age- and sex-related changes in the elderly immune system. …”
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Inflammatory Gene Signature Identified by Machine Algorithms Reveals Novel Biomarkers of Coronary Artery Disease by Liu X, Zhang Y, Wang Y, Xu Y, Xia W, Liu R, Xu S

“…This study aims to investigate the immune responses of peripheral blood mononuclear cells (PBMCs) in CAD and to identify novel signature genes and biomarkers using machine learning algorithms.Methods: The GSE113079 dataset was analyzed and differentially expressed genes (DEGs) were identified between CAD and normal samples. …”
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Optimization of Key Parameters for Coal Seam L-CO₂ Phase Transition Blasting Based on Response Surface Methodology by Xuanping Gong, Xiaoyu Cheng, Cheng Cheng, Quangui Li, Jizhao Xu, Yu Wang

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Investigating the effect of incident intensity on single-junction GaAs PV cells conversion efficiency at different temperatures by Junyue Zhang, Shunhua Wu, Jiachen Liu, Weizhou Huang, Lei Ling, Qingkai Meng, Rui Zhang, Lang Chen, Jiachen Zhang, Zhenfu Wang, Te Li

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Does age still matter? An age-group comparison of self-efficacy, initial interest and performance when learning bystander resuscitation in secondary schools

“…Results: A total of 365 questionnaires and 189 manikin recordings formed the complete dataset. No differences were found between age groups for self-efficacy, outcome expectancies and interest (p > 0.05). …”
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Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment by Kai Zhang, Xiaoxia Liu, Siyu Huang, Xinrui Liu, Meiqi Zhao, Chao Xue, Shijun Xia, Jianzeng Dong, Yu Kong, Changsheng Ma

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Predictors of Functional and Quality of Life Outcomes following Deep Brain Stimulation Surgery in Parkinson’s Disease Patients: Disease, Patient, and Surgical Factors by Hesham Abboud, Gencer Genc, Nicolas R. Thompson, Srivadee Oravivattanakul, Faisal Alsallom, Dennys Reyes, Kathy Wilson, Russell Cerejo, Xin Xin Yu, Darlene Floden, Anwar Ahmed, Michal Gostkowski, Ayman Ezzeldin, Hazem Marouf, Ossama Y. Mansour, Andre Machado, Hubert H. Fernandez

“…There were 130 patients in the dataset. Preoperative and postoperative UPDRS II and EQ-5D were available for 45 patients, PGIS for 67 patients, and CGIS for 116 patients. …”
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Beta-Blockers After PCI for Stable Coronary Artery Disease and Preserved Left Ventricular Ejection Fraction by Safi U. Khan, MD, MS, Usman Ali Akbar, MD, Muhammad Shahzeb Khan, MD, Kershaw V. Patel, MD, Amna Nadeem, MBBS, Samarth Thakkar, MD, Hassaan B. Arshad, MD, Salim S. Virani, MD, PhD, Khurram Nasir, MD, MPH, Sachin S. Goel, MD, Alpesh R. Shah, MD, William Zoghbi, MD, Neal S. Kleiman, MD

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Identification of the optimal candidates to benefit from surgery and chemotherapy among elderly female breast cancer patients with bone metastases by Yuchen Hu, Junfeng Tang, Xiaofeng Liu, Yusheng Sun, Baojun Gong, Qing Gao

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Dietary calcium intake in primary hyperparathyroidism and in its normocalcemic variant: a case-control study by Nicolò Bisceglia, Nicolò Bisceglia, Matteo Malagrinò, Matteo Malagrinò, Anna Piazza, Anna Piazza, Giulia Vandi, Giulia Vandi, Andrea Repaci, Uberto Pagotto, Uberto Pagotto, Guido Zavatta, Guido Zavatta

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SO₂ emissions derived from TROPOMI observations over India using a flux-divergence method with variable lifetimes by Y. Chen, Y. Chen, R. J. van der A, J. Ding, H. Eskes, J. E. Williams, N. Theys, A. Tsikerdekis, P. F. Levelt, P. F. Levelt, P. F. Levelt

“…We present a monthly SO<span class="inline-formula">₂</span> emission inventory for India covering December 2018 to November 2023 based on the Tropospheric Monitoring Instrument (TROPOMI) Level-2 COBRA SO<span class="inline-formula">₂</span> dataset, using an improved flux-divergence method and estimated local SO<span class="inline-formula">₂</span> lifetime, which includes both its chemical loss and dry deposition. …”
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Brain transcriptome analysis of snakehead (Channa argus) under starvation and satiation conditions and identification of differentially expressed gene response to feeding regulatio... by Xiao-yan Jin, Xiu-mei Chen, Gui-liang Guo, Li Sun, Xue-qin Wu, Yun-jie Lin, Xiao-tian Niu, Yi-di Kong, Min Li, Gui-qin Wang

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Agricultural Drought Assessment using Remote Sensing Data (Case study: Tuyserkan County) by Maedeh Malmir, Kamran Shayesteh, Iman Pazhouhan

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Integrating multi‐omics features enables non‐invasive early diagnosis and treatment response prediction of diffuse large B‐cell lymphoma by Weilong Zhang, Bangquan Ye, Yang Song, Ping Yang, Wenzhe Si, Hairong Jing, Fan Yang, Dan Yuan, Zhihong Wu, Jiahao Lyu, Kang Peng, Xu Zhang, Lingli Wang, Yan Li, Yan Liu, Chaoling Wu, Xiaoyu Hao, Yuqi Zhang, Wenxin Qi, Jing Wang, Fei Dong, Zijian Zhao, Hongmei Jing, Yanzhao Li

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Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

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First aid intervention in the adult population: the Yorkshire Health Study and its implications for first aid education

“…Conclusion: Despite the limitations of this study, analysis of this dataset provides a profile of self-defined first aiders in Yorkshire, UK. …”
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